PLoS ONE is the largest open access scientific mega journal published by the Public Library of Science. It uses an innovative editorial process that objectively evaluates scientific validity rather than perceived importance. Since launching in 2006, PLoS ONE has grown rapidly and now publishes over 10,000 articles per year, accounting for around 1.5% of the scientific literature. The success of PLoS ONE has led many major publishers to launch similar open access mega journals that aim to dominate entire fields through large volumes of publications.