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San Diego: An Eco-System for Innovation
“Go to where the puck is going, not where it has been.” – Wayne Gretzky
San Diego’s High Tech History  Series of Catalytic Events 1960 1970 1980 1990 2010 VC Funding 1985 – UCSD CONNECT and                   Qualcomm Founded 1990-93 – 63,000 Jobs Lost 1995 – New                         Boom 1978 – Hybritech  1968 - Linkabit 1963 - Salk Institute  1960 - UCSD Founded 1956 - Scripps Clinic & Research Center  1955 - General Atomics
“The great enemy of truth is very often not the lie … but the myth.” John Fitzgerald Kennedy
The Truth About San Diego No master plan A series of ‘happy accidents’  UCSD had no Business School or resident Tech Transfer when CONNECT began Simultaneous growth of research infrastructure (Salk Institute, Scripps Research Institute, etc) A region blessed with research leadership and vision Decisions were made in the 50’s which put into place the foundation for the future of San Diego
San Diego’s Transformation over the past 25 years Replaced 100,000 jobs lost in defense with 150,000 in new companies – 2/3 high wage 30,000+ employment in biotech; 25,000+ in IT; 12,000 attorneys – when started/800 Highest concentration of biotech in U.S. ,[object Object],The wireless communications capital  ,[object Object]
	Global brands: Qualcomm, Motorola, Nokia$1.3 billion research base; more than doubled $1.2 billion venture capital; increase of 8-10 fold
Access to university researchers Software Development Consulting Entrepreneurial Training & Mentorship Computer Center Accounting & Financial  Research Institute Cancer Research Institute Venture Capitalists Angel Investor Medical School Biotech Facilities Small Business Accelerators Big Pharma Collaborations Engineering School Dept. of Defense Public Relations Trade Organizations M&A Expertise Wireless Research Center Intellectual Property Lawyers Real Estate Business Plan Expertise Biotech Incubators Assistance for getting Government. Grants Corporate Investor Human Resources Presentation Skills Economic Development Agency Workforce Development Initiatives Foreign Investors
It takes a village (or rather, an ecosystem) Entrepreneurs Money Ideas & Inventions Talent Government Coaches & Mentors Trade and Industry Organizations Academia & Research Business Support Services Education &  Workforce Development Access to Global Markets   & Supply Chains Real Estate & Business Infrastructure News and Media Outlets Culture, Societal Values, Role Models,  Rule of Law
Key Conditions for Developing a Technology Cluster Research Industry Clusters Industry Clusters Innovation Intermediary Talent Money Industry Clusters
The Importance of Networks and ‘Boundary Spanners’     They facilitate access and flow of intellectual, financial, and human capital in order to: Address economic transition Capture the benefit of investments in R&D and higher education Build entrepreneurial cultures Create Jobs Help existing industries modernize Diversify economies and create sustainable and renewable wealth Develop regional and global innovation networks They break down hierarchies and allow knowledge to flow
Economic Process          Plantation          Rain Forest
What’s in the rainforest Research capabilities and capacity ,[object Object],Integrative regional and community infrastructure  ,[object Object],Significant private sector engagement Multiple and continuous collaborations and alliances Engagement of leaders and champions of innovation who are not always the usual suspects Adaptive and flexible environment  Multiple forms of investment ,[object Object],Talent development
Knowledge is the Key to Innovation
Principles and Values of Successful Innovation Systems ,[object Object]
Knowledge and creativity are the critical resources for innovation
Science and Technology innovations are global from ‘birth’
Shared definitions matter
Networks must be established which serve to breakdown social and professional hierarchies and drive lateral learning / knowledge transfer
Relationships Trust  Transaction
Mistakes ≠ Failures
Attitude = ‘Community over Company’,[object Object]
Must  be able to harness the ‘collective intelligence’ (i.e. ‘Wisdom of Crowds’)
You must teach in the manner that entrepreneurs ‘learn’
Non linear
Just in time
Peer network driven
Curious and Passionate
Companies are built by teams, not by individuals (teach teams),[object Object]
Shared Risk and Rewards…sustainability comes from creating a collective sense of ‘ownership’
The ‘Parking Lot’ principle
Commercialization is a ‘Body Contact’ sport,[object Object]
28,867 researchers work within  4 mile radius 4  Miles La Jolla Mesa Zip Codes SD Total Research Base: 38,934
The University of California is a key driver in California biotech ,[object Object]
1 in 4 Public Biotechs are within 35 miles of a UC Campus
1 in 6 Public Biotechs was founded by a UC scientists
1 in 3 California Biotechs was founded by UC scientistsSource: Industry-University Cooperative Research Program
Sources of Financial Capital ,[object Object]
Grants & Foundations
Business Angels
Institutional and Corporate Venture Capital
Public Markets,[object Object]
Venture Capital in San Diego Amgen Ventures Ampersand Ventures Athenian Ventures Avalon Capital Group Avalon Ventures Biogen Idec Domain Associates Enterprise Partners Express Ventures Forward Ventures GMT Ventures Hamilton BioVentures Hamilton Tech Capital Partners Inglewood Ventures Innocal Ventures JMI Equity Johnson & Johnson Kinovate Life Sciences Leading Ventures Mesa Verde Miramar Venture Partners ,[object Object]
Montreux Capital Partners

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3. 2011 san diego connect global connect

Editor's Notes

  1. 1. Research capabilities and capacity: clusters form around a critical mass of top tier science and technology 2. Regional Infrastructure: both physical and ‘soft’. Everything from buildings and roads, to educational programs and workforce development initiatives. Including what Richard Florida calls ‘amenities of place’3. Significant private sector engagement. Innovative science based companies require multiple stakeholders who are actively involved in their path from lab to market. This includes people with domain knowledge, as well as market, business, finance, management, and other skills that will allow these companies to grow and sustain themselves. Is the private sector engaged, or do they wait for government to lead? Are they collaborative, or do they protect themselves by being secretive? It is also important that industry is engaged early in the process, pre-transaction. This market input assures these opportunities show proof of relevance, and not just proof of concept. 4. Multiple continuous collaborations and alliances: self explanatory5. Leaders and champions: not the usual suspects. Many of these people are not household names, but posess the energy, desire, and vision for what needs to be accomplished. Who are the integrative thinkers who have influence and impact?. We have observed that often, the most effective of these have lived or worked in places where the culture was evolved with respect to research and business collaboration /commercialization. As Darwin said, it is not the strongest of the species, nor the most intelligent, but the most responsive to change. This is the key. Do not build your ecosystems for perfection, but rather, for iteration and evolution. Successful communities have a continuum of capital that serves the needs of start ups and early stage research. It is important that this diverse set of financial resources work in harmony with one another. In addition, other forms of investment, including time and the sharing of personal / professional connections, as well as pro bono services of services and tangible assets be available. Finally, in order to keep these ecosystems healthy, they need talent. Not only management and leadership, but the workers who are the fuel to the engine of innovation and commerce. In that respect, a region that possesses an integrated workforce development strategy and proactive ways of constantly transferring knowledge to the workers in the field, will be the most sustainable. People are truly the ultimate technology transfer. It is also important that regions find ways to celebrate their successes in a way that is visible. This helps spur on the next generation of entrepreneurs and innovators.
  2. Access to diverse forms of financing -- seed, angel, venture, corporateBusiness planning and market intelligenceDomain experience and management “know-how”Continuing education and training for professionalsAwareness for local, regional and national issues impacting technology sectors
  3. 117 people hired full timePart-time was 64 or 250%75% are still in business50 Companies have raised almost $120 M still graduating
  4. Companies and countries from all over the world come to CONNECT to find out how we were successful and how they can replicate our success. As an example. The government of the UK commissioned by the Prime Minister studied CONNECT has advocated the creation of a CONNECT-like system in England to transform the Innovation Economy.