June 2016
Professor in Personalized Healthcare
Head Radboud Center for Proteomics, Glycomics
and Metabolomics
Coordinator Radboud Technology CentersProf Alain van Gool
alain.vangool@radboudumc.nl
• Nijmegen, The Netherlands
• Mission: “To have a significant impact on healthcare”
• Strategic focus on Personalized Healthcare through
“the patient as partner”
• Core activities:
• Patient care
• Research
• Education
• 11.000 colleagues
• 52 departments
• 3.300 students
• 1.000 beds
Radboud university medical center
2
Radboud campus:
- Radboudumc
- Radboud University
- Hogeschool Arnhem Nijmegen
- Max Planck Institute
- Multiple companies
Patient
Radboud
Personalized Healthcare
A significant impact
on healthcare
Molecule
Population
3
Research themes and institutes
www.radboudumc.nl/Research/Themes/Pages/default.aspx
4
Orientation across the spectrum
from molecule to man to population
Orientationacross
thespectrumofdiseases
PI
Research Theme
TechnologyCenter
Research support by Technology
5
Radboudumc Technology Infrastructure
Get organised:
1. What technological expertise do we have and should we have ?
2. How should we organise this ?
3. How will we communicate this ?
6
6
External role
Internal role
• Knowledge hub for technological expertise
• Maximise use of available technical capabilities and knowledge (‘duurzaamheid’)
• Advise scientists with technological expertise
• Advise management on strategic investments and opportunities
• Drive innovations by working with each other, research theme’s and Valorisation
• Easy access to Radboudumc’s technological expertise
• Represent Radboudumc as one in external technology networks
• Increase funding (grants, contract research)
Internal / external role
Radboudumc Technology Centers
7
7
Technology Platforms UMC St Radboud
(Potential)
Technology
Platforms
Genomics
RPC
CMBI
PRIME
MIC
CDL
CRCN
Radboud
BiobankMalaria lab
Flow
cytometry
TR&CT
TNU
MITeC
PDRC
December 2013
8
Inventory phase
8
Radboudumc Technology Centers
Genomics
Bioinformatics Animal
studies
Flow
cytometry
Translational
neuroscience
Image-guided
treatment
Imaging
Microscopy
Biobank
Data
stewardship
Proteomics
Glycomics
Metabolomics
Radboudumc
Technology
Centers
GMP products
Clinical
trials
January 2014
9
Repositioning phase
9
Radboudumc Technology Centers
Improving phase
10
Feb-Oct 2014
10
Radboudumc Technology Centers
Improving phase
11
Feb-Oct 2014
11
www.radboudumc.nl/research/technologycenters
Genomics
Bioinformatics
Animal
studies
Stem
cells
Translational
neuroscience
Image-guided
treatment
Imaging
Microscopy
Biobank
Health
economics
Mass
Spectrometry
Radboudumc
Technology
Centers
Investigational
products
Clinical
studies
EHR-based
research
Statistics
Human
performance
Data
stewardship
Molecule
Flow
cytometry
12
Implementation phase
Nov 2014 -
Opening Radboud Research Facilities, 2nd Oct 2014
Point of contact: Alain van Gool
About 250 dedicated people working in 18 Technology Centers, ~1600 users (internal, external), ~140 consortia
www.radboudumc.nl/research/technologycenters/
13
Genomics
Bioinformatics
Animal
studies
Stem
cells
Translational
neuroscience
Image-guided
treatment
Imaging
Microscopy
Biobank
Health
economics
Mass
Spectrometry
Radboudumc
Technology
Centers
Investigational
products
Clinical
trials
EHR-based
research
Statistics
Human
physiology
Data
stewardship
Molecule
Flow
cytometry
About 250 dedicated people working in 18 Technology Centers, ~1600 users (internal, external), ~140 consortia
www.radboudumc.nl/research/technologycenters/
• Proteins
• Metabolites
• Drugs
• PK-PD
• Preclinical
• Clinical
• Behavioural
• Preclinical
• Animal facility
• Systematic review
• Cell analysis
• Sorting
• Pediatric
• Adult
• Phase 1, 2, 3, 4
• Vaccines
• Pharmaceutics
• Cyclotron
• Radio-isotopes
• Malaria parasites
• Management
• Analysis
• Sharing
• Cloud computing
• DNA
• RNA
• Internal
• External
• Early HTA
• Evidence-based
surgery
• Field lab
• Statistics
• Biological
• Structural
• Preclinical
• Clinical• Economic
viability
• Decision
analysis
• Experimental design
• Biostatistical advice
• Electronic Health Records
• Big Data
• Best practice
• In vivo
• Functional
diagnostics
• iPSC
• Organoids
14
Visibility
• Logo
• Key figures
• Website
• Leaflets
• Lectures
Combination of
• Science
• Business
• Innovation
• Impact in healthwww.radboudumc.nl/research/technologycenters/
(1H2015: 1.900 unique visitors, 26.000 page views)
Working together on the Radboud campus
(Spin-out)
companies
16
Radboud Research Facilities
• Shared facilities across Radboud campus, also made part of Gelderland facilities
• Initiated by funding 6.2M Eur Gelderland + 6.2M Eur Radboud University/ Radboudumc
www.ru.nl/radboudresearchfacilities/
17
Working with other networks
Region, nation, Europe, world
18
Next steps
• Collaboration
• Organisation of individual RTC’s
• Interactions/collaborations/cross-selling between RTC’s
• Research themes – Technology centers
• Networks
• Local/regional/national/international
• Support
• Cash, kind
19

2016 06 Radboud Technology Centers

  • 1.
    June 2016 Professor inPersonalized Healthcare Head Radboud Center for Proteomics, Glycomics and Metabolomics Coordinator Radboud Technology CentersProf Alain van Gool alain.vangool@radboudumc.nl
  • 2.
    • Nijmegen, TheNetherlands • Mission: “To have a significant impact on healthcare” • Strategic focus on Personalized Healthcare through “the patient as partner” • Core activities: • Patient care • Research • Education • 11.000 colleagues • 52 departments • 3.300 students • 1.000 beds Radboud university medical center 2 Radboud campus: - Radboudumc - Radboud University - Hogeschool Arnhem Nijmegen - Max Planck Institute - Multiple companies
  • 3.
    Patient Radboud Personalized Healthcare A significantimpact on healthcare Molecule Population 3
  • 4.
    Research themes andinstitutes www.radboudumc.nl/Research/Themes/Pages/default.aspx 4
  • 5.
    Orientation across thespectrum from molecule to man to population Orientationacross thespectrumofdiseases PI Research Theme TechnologyCenter Research support by Technology 5
  • 6.
    Radboudumc Technology Infrastructure Getorganised: 1. What technological expertise do we have and should we have ? 2. How should we organise this ? 3. How will we communicate this ? 6 6
  • 7.
    External role Internal role •Knowledge hub for technological expertise • Maximise use of available technical capabilities and knowledge (‘duurzaamheid’) • Advise scientists with technological expertise • Advise management on strategic investments and opportunities • Drive innovations by working with each other, research theme’s and Valorisation • Easy access to Radboudumc’s technological expertise • Represent Radboudumc as one in external technology networks • Increase funding (grants, contract research) Internal / external role Radboudumc Technology Centers 7 7
  • 8.
    Technology Platforms UMCSt Radboud (Potential) Technology Platforms Genomics RPC CMBI PRIME MIC CDL CRCN Radboud BiobankMalaria lab Flow cytometry TR&CT TNU MITeC PDRC December 2013 8 Inventory phase 8
  • 9.
    Radboudumc Technology Centers Genomics BioinformaticsAnimal studies Flow cytometry Translational neuroscience Image-guided treatment Imaging Microscopy Biobank Data stewardship Proteomics Glycomics Metabolomics Radboudumc Technology Centers GMP products Clinical trials January 2014 9 Repositioning phase 9
  • 10.
  • 11.
  • 12.
  • 13.
    Opening Radboud ResearchFacilities, 2nd Oct 2014 Point of contact: Alain van Gool About 250 dedicated people working in 18 Technology Centers, ~1600 users (internal, external), ~140 consortia www.radboudumc.nl/research/technologycenters/ 13 Genomics Bioinformatics Animal studies Stem cells Translational neuroscience Image-guided treatment Imaging Microscopy Biobank Health economics Mass Spectrometry Radboudumc Technology Centers Investigational products Clinical trials EHR-based research Statistics Human physiology Data stewardship Molecule Flow cytometry
  • 14.
    About 250 dedicatedpeople working in 18 Technology Centers, ~1600 users (internal, external), ~140 consortia www.radboudumc.nl/research/technologycenters/ • Proteins • Metabolites • Drugs • PK-PD • Preclinical • Clinical • Behavioural • Preclinical • Animal facility • Systematic review • Cell analysis • Sorting • Pediatric • Adult • Phase 1, 2, 3, 4 • Vaccines • Pharmaceutics • Cyclotron • Radio-isotopes • Malaria parasites • Management • Analysis • Sharing • Cloud computing • DNA • RNA • Internal • External • Early HTA • Evidence-based surgery • Field lab • Statistics • Biological • Structural • Preclinical • Clinical• Economic viability • Decision analysis • Experimental design • Biostatistical advice • Electronic Health Records • Big Data • Best practice • In vivo • Functional diagnostics • iPSC • Organoids 14
  • 15.
    Visibility • Logo • Keyfigures • Website • Leaflets • Lectures Combination of • Science • Business • Innovation • Impact in healthwww.radboudumc.nl/research/technologycenters/ (1H2015: 1.900 unique visitors, 26.000 page views)
  • 16.
    Working together onthe Radboud campus (Spin-out) companies 16
  • 17.
    Radboud Research Facilities •Shared facilities across Radboud campus, also made part of Gelderland facilities • Initiated by funding 6.2M Eur Gelderland + 6.2M Eur Radboud University/ Radboudumc www.ru.nl/radboudresearchfacilities/ 17
  • 18.
    Working with othernetworks Region, nation, Europe, world 18
  • 19.
    Next steps • Collaboration •Organisation of individual RTC’s • Interactions/collaborations/cross-selling between RTC’s • Research themes – Technology centers • Networks • Local/regional/national/international • Support • Cash, kind 19