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Copyright © 2013 QuintilesCopyright © 2013 Quintiles
2014 Wells Fargo
Healthcare Conference
June 17, 2014
NYSE: Q
2
Forward Looking Statements and
Use of Non-GAAP Financial Measures
This presentation contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933,
as amended and Section 21E of the Securities Exchange Act of 1934, as amended. Such forward-looking statements
reflect, among other things, the Company’s current expectations and anticipated results of operations, all of which are
subject to known and unknown risks, uncertainties and other factors that may cause actual results, performance or
achievements, market trends or industry results to differ materially from those expressed or implied by such forward-
looking statements. Therefore, any statements contained herein that are not statements of historical fact may be
forward-looking statements and should be evaluated as such. Without limiting the foregoing, the words “anticipates,”
“believes,” “estimates,” “expects,” “intends,” “may,” “plans,” “projects,” “should,” “guidance,” “targets,” “will” and the
negative thereof and similar words and expressions are intended to identify forward-looking statements. Actual results
may differ materially from the Company’s expectations due to a number of factors, including that most of the
Company’s contracts may be terminated on short notice, the Company may be unable to maintain large customer
contracts or to enter into new contracts, the Company may under-price its contracts, overrun its cost estimates, or fail to
receive approval for or experience delays in documenting change orders; the historical indications of the relationship of
backlog to revenues may not be indicative of their future relationship, the complex and changing regulatory and
international environments in which the Company operates, the Company may be unable to successfully identify,
acquire and integrate businesses, the Company’s substantial indebtedness, and other risks more fully set forth in the
Company's filings with the SEC, including the Company’s annual report on Form 10-K for the fiscal year ended
December 31, 2013, filed with the SEC on February 13, 2014, as such factors may be amended or updated from time
to time in the Company’s periodic filings with the SEC, which are accessible on the SEC's website at www.sec.gov.
Unless legally required the Company assumes no obligation to update any forward-looking statement after the date of
this presentation, whether as a result of new information, future developments or otherwise.
This presentation includes financial measures not prepared in accordance with accounting principles generally
accepted in the United States (“GAAP”). Management believes that these non-GAAP financial measures provide useful
supplemental information to management and investors regarding the underlying performance of the Company’s
business operations and are more indicative of core operating results as they exclude certain items whose fluctuations
from period-to-period do not necessarily correspond to changes in the core operations of the Company’s
business. Investors and potential investors are encouraged to review the reconciliations of the non-GAAP financial
measures to their most directly comparable GAAP measures attached to this presentation.
3
Enterprise Vision and Strategy
Quintiles
Vision
We bring people and
knowledge together for a
healthier world
Our Customer Promise
Improve your
probability of success“
“
Excellence at
Global People,
Process &
Technology
Scientific,
Therapeutic & Rx
Experience
Quantitative
& Analytical
Expertise
Profitable growth at above
market rates
Lead with investments
that leverage our scale
and differentiate us
(Science, Technology,
Global Workforce)
World-class customer
relationship management
and offerings that provide
value to customers
Drive Productivity,
Delivery and Quality, and
measure our success
Top-quality leadership
development and a high-
performance workforce
Our Strategic Agenda
Biopharma Product
Development
Clinical
Services
Differentiated
Offerings
New
Markets
Integrated
Healthcare Services
Commercial
Services
Differentiated
Offerings
New
Markets
4
Stability and Long-term Momentum
Backlog and Book-to-Bill(1,4)
(1) See appendix slide 15 for reconciliation of Service Revenues to Adjusted Service Revenues
(2) See slide 16 for reconciliation of Net Income to Adjusted EBITDA
Adjusted Service Revenues(1)
’10 – ’13 CAGR = 8.3%
Adjusted EBITDA(2)
’10 – ’13 CAGR = 9.7%
Net New Business
’10 – ’13 CAGR = 11.3%
$Millions
$Millions
$Millions
$3,552
$4,044
$4,501
$4,899
0
1,000
2,000
3,000
4,000
5,000
2010 2011 2012 2013
$2,997
$3,295
$3,692
$3,808
0
1,000
2,000
3,000
4,000
2010 2011 2012 2013
$463
$490
$544
$612
0
100
200
300
400
500
600
700
2010 2011 2012 2013
$Millions
$7,115
$7,973
$8,705
$9,855
1.19x 1.23x 1.22x
1.29x
0.00x
0.50x
1.00x
1.50x
2.00x
0
2,500
5,000
7,500
10,000
2010 2011 2012 2013
(3) Margin is defined as Adjusted EBITDA divided by Adjusted Service Revenues as shown on slide 16
(4) Book-to-bill calculated as NNB divided by Adjusted Service Revenues
15.4% 14.9% 14.7% 16.1%Margin
(3)
Consistent Gains Underpinned with a Low Customer Concentration
5
Continued Momentum in 2014
Financial Results - Three Months Ended March 31, 2014
O T H E R H I G H L I G H T S
1.27x Book-to-bill ratio
- 1.30x in Product Development
- 1.15x in Integrated Healthcare
Services
$741mm Cash and cash equivalents
(1) See appendix slide 19
57.8% Adjusted Net Income growth
140 bps Adjusted Income from Operations
margin(1) expansion
$10.1bn Total Backlog
Seven sequential quarters of net
new business exceeding $1.0bn
$1.3bn
F I N A N C I A L H I G H L I G H T S
Constant Currency Revenue(1)
- 8.6% in Product Development
-7.9% in Integrated Healthcare Services
-Second sequential billion dollar service
revenue quarter
8.4%
38.8% Diluted Adjusted EPS growth
6
$93bn Product Development Market(1)
Attractive and Growing Market
~$200bn addressable market with growth of 5% - 8% per year from 2013 - 2016
 $51bn Addressable Phase I-IV Clinical
 $19bn Outsourced Phase I-IV Clinical ~37%
 Outsourced Market penetration is estimated to increase by
200-300 basis points per year approaching 47% outsourced
in 2017
 The central lab market growth rate is estimated at 4.5% -
5% from 2013 – 2016 with an increase in test complexity
$94bn(1,2) Integrated Healthcare Services Market
 $16bn Outsourced ~17%
 Market penetration is estimated to increase by 150-200
basis points per year
 Broad customer interest in variabalizing cost
 New product launches are expected to increase with the
recent increase in NMEs; 27 in ‘13, 39 in ‘12, and 30 in ‘11
(1) Based on Company estimates
(2) Includes market access, reimbursement, observational studies, comparative effectiveness research, health economics & outcomes research, and commercial consulting
(3) Segment Income from Operations
Approval
Phase I Phase II Phase III Healthcare
Delivery
Product Development
Commercial
Product Development Services
(93% of Operating Profit) (3)
Integrated Healthcare Services (“IHS”)
(7% of Operating Profit) (3)
Phase
IV
Late Phase
Interventional
Project Management & Clinical Monitoring
Clinical Trial Support (Central Lab, Biostatistics, Data
Management, Technology, etc.)
Product Development Consulting (Strategic Planning & Design)
Commercial Focused Services
Late Phase / Observational
Other
Healthcare
Solutions
Consulting, Market Access
7
Evolving Biopharma Landscape
Growth, inefficiency and complexity play to Quintiles’ strength
Higher NME
Approvals
Larger
Pipelines
R&D
Spending
Increasing
Outsourcing
Penetration
Personalized
Medicine
Increasing
Trial
Complexity R&D spending grew
~1.5%4 in 2013 and is
forecasted to grow
0%-2% through 20163
1 M. Allison, Reinventing clinical trials, Nature Biotechnology 30, no 1 (2012): 41-49; Median procedures calculated on a three year basis: 2000-2003 and 2008-2011 .
2 Decision Resources, November 2013.
3 Based on Company estimates. 4EvaluatePharma. 5 www.fda.gov. 6PharmaProjects, January 2014.
Outsourcing is increasing
by ~2 percentage points
each year3
The median number of procedures
per trial increased by 57% between
2003 and 20111
4,0606 drugs in the
Phase I-III pipeline in
2013, a 19% increase
over 2008
FDA approved 27 NMEs in 2013, 39 in
2012, and 30 in 2011. From 2006-2010, the
average number of approvals was 225
Over 3,000 ongoing clinical
trials involve a biomarker or
predictive diagnostic
2
Industry
Growth
R&D
Complexity
Biopharma restructurings
Trial Design Regulatory Market Access Commercial Pathways Scientific DepthMedical Expertise
8
Deep Customer Relationships
Largest Backlog in Industry Providing Consistency, Sustainability
and Diversification
These Relationships Provide Durable Performance Today And Position Quintiles For
Increases In Addressable Market Share
Worked with all top 20 biopharma companies in each of last 11 years
All of our top 25 key customers worked with both Quintiles segments: PD and IHS
$100mm+ service revenues from at least 8 customers in each of past 6 years
~65% of service revenues outside of US
~51% of 2013 net new business from outside the Top 20 Pharma
< 10% of revenues from largest customer – diverse customer base
Worked with over 500 biopharma customers
C-Level access and relationships
9
> Depth and breadth of service offerings
enabled the win of 2 sole provider deals
in 2013
Leader of innovative models
The Leader in BioPharma Services
Why We Win = Enhanced Value for Customers
• Clearly differentiated service offerings
> Improving probability of success
> Provided services to develop or commercialize
top 50 best selling biopharmaceutical and
biologic products from 2012
• Deepest medical and therapeutic,
statistical, and quantitative expertise in the
industry
> 950 medical doctors and 900 Ph.D.’s
> 14 therapeutic centers of excellence
• Personalized medicine
> Solutions include the integration of biomarkers
and genomics, with novel genomic pre-
profiling
• Focused on real-world cost effectiveness
> Portfolio prioritization and market access
consulting capabilities
> 80+ risk-based monitoring trials across
20,000+ sites
> ~3,200 employees in Global Delivery
Network
> Award winning technology
Leader in remote (risk-based) monitoring
> Implemented > 350 patient registries and
post approval programs
Leader in real-world data
Leader in adaptive trial design
10
Product Development
• Core Segment representing 77% of Consolidated
Service Revenues and 93% of Segment Income from
Operations(1)
• Market leader in Product Development services
> #1 in Clinical Development / #2 in Central Lab
• Diversified customer portfolio across BioPharma
segments with tailored segment solutions
• Integrated offerings across services and platforms
• Proactive Business Development
> 1.30 book-to-bill ratio - highest in five sequential quarters
> Strong RFP volumes
> Evolution of integrated end to end partnership models
> Strong wins across Large, Mid-size and Emerging
Pharma
Ph - I Ph - II Ph - III Ph-IIIB & IV
Product Development Services
Technology and Informatics
Deep Science, Therapeutic, &
Regulatory Expertise
Globally Harmonized Best in
Class Processes
Novel Approaches to
Development
Global Workforce
(1) For full year 2013.
Accelerating pipelines using science, technology and global delivery
11
Integrated Healthcare Services
• IHS Segment represents 23% of Consolidated
Service Revenues and 7% of Segment Income
from Operations(1)
• IHS includes market leading solutions
> One of the leading outsourced global contract
pharmaceutical sales organization
> One of the leading observational services organizations
• Convergence within Healthcare
> IHS solutions are aligned to capitalize on the evolving
convergence of patient, payer and provider, solutions to
leverage evidence-based insights into commercial
strategies to provide an integrated approach
• Thought Leadership in consulting and
observational research
• Three consecutive quarters of strong net new
business
Integrated Healthcare Services
Offerings
Commercial Services:
• Contract Sales
• Market Entry / Market Exit
• Integrated Channel Management
• Patient Engagement Services
• Market Access & Commercialization
Consulting
• Medical Education
Real-World and Late Phase Research:
• Observational Studies
• Product and Disease Registries
• Comparative Effectiveness Studies
Other Healthcare Solutions
• Encore
Integrated Healthcare Services
Phase II & III Commercial Healthcare Delivery
> 60mm
De-identified patient
records
> 9mm
Patients enrolled in
registries
> 450
Clinical Educators
> 120
Launched products in
US
~ 100%
Field based resources trained
on compliance programs
Communications & Engagement
Services:
• Digital Patient Services
• Brand & Scientific Communications
(1) For full year 2013.
Improving the probability of commercial success
12
Encore
Real World Evidence Provides Improved Outcomes
Rationale
• Enhances provider relationships and access to population health market
• Adds EMR and meaningful use capabilities
• Natural supplement to Real World Late Phase business
• Creates opportunity for future product & service offerings
The Business
• Experienced and proven management team
• A leader in the EMR implementation and optimization with advisory consulting capabilities and emerging
analytics capabilities in hospital quality metrics
• Deep relationships with leading providers such as Tenet Healthcare, Carolinas Healthcare System, Carilion
Clinic
• 250 consultants
Integration
• Operating unit with Integrated Healthcare Services segment
Transaction
• Announced May 12, 2014
• Capability enhancing transaction
13
Quintiles
An Attractive Investment
Market leader in
Product Development
services
Deep and diverse customer
relationships with no customer
contributing 10% or more of revenues
Serve an attractive and
growing market
Geographically
diversified revenue base
Strong free
cash flow
First mover advantage with Clinical
Development Informatics technology
in the CRO industry
Forward looking revenue visibility
from largest backlog in industry
Best in industry operating margins
with a consistent focus on process
and productivity leverage
Long-term consistent
financial performance
14
Appendix
15
Adjusted Service Revenues
Reconciliation
Adjusted Service Revenues Reconciliation
Year Ended December 31
(In Thousands) 2013 2012 2011 2010
Non-GAAP Adjusted Service Revenues:
GAAP Service Revenues as Reported $3,808,340 $3,692,298 $3,294,966 $3,060,950
Deconsolidation of PharmaBio -– – – (64,198)
Adjusted Service Revenues $3,808,340 $3,692,298 $3,294,966 $2,996,752
16
Adjusted EBITDA Reconciliation
Adjusted EBITDA Reconciliation
Year Ended December 31
(In Thousands) 2013 2012 2011 2010
Non-GAAP Adjusted EBITDA:
GAAP Net Income as Reported $226,027 $176,631 $240,327 $165,255
Interest Expense, Net 119,571 131,304 105,126 137,631
Income Tax Expense 95,965 93,364 15,105 77,582
Depreciation and Amortization 107,504 98,288 92,004 84,217
Restructuring Costs 14,071 18,741 22,116 22,928
Impairment Charges – – 12,295 2,844
Incremental Share-based Compensation Expense – 13,637 2,553 –
Bonus Paid to Certain Holders of Stock Options – 11,308 10,992 –
Management Fees 27,694 5,309 5,213 5,159
Loss on Extinguishment of Debt 19,831 1,275 46,377 –
Other (Income) Expense, Net (185) (3,572) 9,073 15,647
Equity in Losses (Earnings) from Unconsolidated Affiliates 1,124 (2,567) (70,757) (1,110)
Deconsolidation of PharmaBio – – – (47,393)
Adjusted EBITDA $611,602 $543,718 $490,424 $462,760
% of Adjusted Service Revenues 16.1% 14.7% 14.9% 15.4%
17
Adjusted Net Income Reconciliation
Adjusted Net Income Reconciliation
Year Ended December 31
(In Thousands) 2013 2012 2011 2010
Non-GAAP Adjusted Net Income:
GAAP Net Income as Reported $226,027 $176,631 $240,327 $165,255
Net (Income) Loss Attributable to Noncontrolling Interests 564 915 1,445 (4,659)
Restructuring Costs 14,071 18,741 22,116 22,928
Impairment Charges – – 12,295 2,844
Incremental Share-based Compensation Expense – 13,637 2,553 –
Bonus Paid to Certain Holders of Stock Options – 11,308 10,992 –
Management Fees 27,694 5,309 5,213 5,159
Loss on Extinguishment of Debt 19,831 1,275 46,377 –
Interest Rate Swap Termination Fee – – 11,630 –
Gain on Sale of Business Assets – – (74,880) –
Deconsolidation of PharmaBio – – – (28,979)
Tax Effect of Non-GAAP Adjustments (22,304) (18,885) (21,063) (752)
Other Income tax Adjustments 3,057 – (66,000) –
Adjusted Net Income $268,940 $208,931 $191,005 $161,796
% of Adjusted Service Revenues 7.1% 5.7% 5.8% 5.4%
18
Income Statement
GAAP – Non-GAAP Reconciliation
Three Months Ended March 31
(millions of dollars)
Selling,
General and
Administrative
Income
from
Operations
Net Income
Attributable
to Quintiles
Selling,
General and
Administrative
Income
from
Operations
Net Income
Attributable
to Quintiles
As Reported $ 219.2 $ 141.3 $ 90.2 $ 199.3 $ 115.2 $ 48.3
Adjustments
Restructuring Costs - 1.0 1.0 - 1.9 1.9
Management Fees - - - (1.3) 1.3 1.3
Tax Effect of Adjustments - - (0.3) - - (1.2)
Other Income Tax Adjusments - - - - - 7.3
Adjusted Non-GAAP Basis $ 219.2 $ 142.3 $ 90.9 $ 198.0 $ 118.4 $ 57.6
% of Service Revenues 21.8% 14.2% 9.0% 21.4% 12.8% 6.2%
2014 2013
1Represents the Company’s change in its permanent reinvestment assertion during 2Q 2013 retroactively applied to1Q 2013 for the new
estimated annual effective income tax rate.
1
19
Constant Currency Reconciliation
Service Revenues and Income from Operations
Service revenues exchange impact equals the current period service revenues for foreign currency denominated contracts recalculated at the
prior period exchange rates less the current period service revenues, while the exchange rate impacts on expenses equals the current period
expenses recalculated at the prior period exchange rates less the current period expenses at actual rates.
The segment detail presented above excludes general corporate and unallocated expenses and restructuring costs.
(millions of dollars)
Consolidated Actual
Exchange
Impact Constant Actual
Exchange
Impact Constant
Service Revenues 1,005.3$ (0.5)$ 1,005.8$ 8.4% 0.0% 8.4%
Income from Operations 141.3$ 10.2$ 131.1$ 22.7% 8.9% 13.8%
Adjusted Income from Operations 142.3$ 10.2$ 132.1$ 20.2% 8.6% 11.6%
Adjusted Income from Operations Margin 14.2% 13.1%
Product Development
Service Revenues 770.8$ 3.7$ 767.1$ 9.1% 0.5% 8.6%
Income from Operations 160.6$ 11.0$ 149.6$ 21.1% 8.3% 12.8%
Income from Operations Margin 20.8% 19.5%
Integrated Healthcare Services
Service Revenues 234.5$ (4.2)$ 238.7$ 6.0% (1.9%) 7.9%
Income from Operations 9.0$ (0.9)$ 9.9$ 43.2% (13.1%) 56.3%
Income from Operations Margin 3.8% 4.1%
Three Months Ended March 31 Year on Year Growth

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2014 Wells Fargo Healthcare Conference

  • 1. Copyright © 2013 QuintilesCopyright © 2013 Quintiles 2014 Wells Fargo Healthcare Conference June 17, 2014 NYSE: Q
  • 2. 2 Forward Looking Statements and Use of Non-GAAP Financial Measures This presentation contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended and Section 21E of the Securities Exchange Act of 1934, as amended. Such forward-looking statements reflect, among other things, the Company’s current expectations and anticipated results of operations, all of which are subject to known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements, market trends or industry results to differ materially from those expressed or implied by such forward- looking statements. Therefore, any statements contained herein that are not statements of historical fact may be forward-looking statements and should be evaluated as such. Without limiting the foregoing, the words “anticipates,” “believes,” “estimates,” “expects,” “intends,” “may,” “plans,” “projects,” “should,” “guidance,” “targets,” “will” and the negative thereof and similar words and expressions are intended to identify forward-looking statements. Actual results may differ materially from the Company’s expectations due to a number of factors, including that most of the Company’s contracts may be terminated on short notice, the Company may be unable to maintain large customer contracts or to enter into new contracts, the Company may under-price its contracts, overrun its cost estimates, or fail to receive approval for or experience delays in documenting change orders; the historical indications of the relationship of backlog to revenues may not be indicative of their future relationship, the complex and changing regulatory and international environments in which the Company operates, the Company may be unable to successfully identify, acquire and integrate businesses, the Company’s substantial indebtedness, and other risks more fully set forth in the Company's filings with the SEC, including the Company’s annual report on Form 10-K for the fiscal year ended December 31, 2013, filed with the SEC on February 13, 2014, as such factors may be amended or updated from time to time in the Company’s periodic filings with the SEC, which are accessible on the SEC's website at www.sec.gov. Unless legally required the Company assumes no obligation to update any forward-looking statement after the date of this presentation, whether as a result of new information, future developments or otherwise. This presentation includes financial measures not prepared in accordance with accounting principles generally accepted in the United States (“GAAP”). Management believes that these non-GAAP financial measures provide useful supplemental information to management and investors regarding the underlying performance of the Company’s business operations and are more indicative of core operating results as they exclude certain items whose fluctuations from period-to-period do not necessarily correspond to changes in the core operations of the Company’s business. Investors and potential investors are encouraged to review the reconciliations of the non-GAAP financial measures to their most directly comparable GAAP measures attached to this presentation.
  • 3. 3 Enterprise Vision and Strategy Quintiles Vision We bring people and knowledge together for a healthier world Our Customer Promise Improve your probability of success“ “ Excellence at Global People, Process & Technology Scientific, Therapeutic & Rx Experience Quantitative & Analytical Expertise Profitable growth at above market rates Lead with investments that leverage our scale and differentiate us (Science, Technology, Global Workforce) World-class customer relationship management and offerings that provide value to customers Drive Productivity, Delivery and Quality, and measure our success Top-quality leadership development and a high- performance workforce Our Strategic Agenda Biopharma Product Development Clinical Services Differentiated Offerings New Markets Integrated Healthcare Services Commercial Services Differentiated Offerings New Markets
  • 4. 4 Stability and Long-term Momentum Backlog and Book-to-Bill(1,4) (1) See appendix slide 15 for reconciliation of Service Revenues to Adjusted Service Revenues (2) See slide 16 for reconciliation of Net Income to Adjusted EBITDA Adjusted Service Revenues(1) ’10 – ’13 CAGR = 8.3% Adjusted EBITDA(2) ’10 – ’13 CAGR = 9.7% Net New Business ’10 – ’13 CAGR = 11.3% $Millions $Millions $Millions $3,552 $4,044 $4,501 $4,899 0 1,000 2,000 3,000 4,000 5,000 2010 2011 2012 2013 $2,997 $3,295 $3,692 $3,808 0 1,000 2,000 3,000 4,000 2010 2011 2012 2013 $463 $490 $544 $612 0 100 200 300 400 500 600 700 2010 2011 2012 2013 $Millions $7,115 $7,973 $8,705 $9,855 1.19x 1.23x 1.22x 1.29x 0.00x 0.50x 1.00x 1.50x 2.00x 0 2,500 5,000 7,500 10,000 2010 2011 2012 2013 (3) Margin is defined as Adjusted EBITDA divided by Adjusted Service Revenues as shown on slide 16 (4) Book-to-bill calculated as NNB divided by Adjusted Service Revenues 15.4% 14.9% 14.7% 16.1%Margin (3) Consistent Gains Underpinned with a Low Customer Concentration
  • 5. 5 Continued Momentum in 2014 Financial Results - Three Months Ended March 31, 2014 O T H E R H I G H L I G H T S 1.27x Book-to-bill ratio - 1.30x in Product Development - 1.15x in Integrated Healthcare Services $741mm Cash and cash equivalents (1) See appendix slide 19 57.8% Adjusted Net Income growth 140 bps Adjusted Income from Operations margin(1) expansion $10.1bn Total Backlog Seven sequential quarters of net new business exceeding $1.0bn $1.3bn F I N A N C I A L H I G H L I G H T S Constant Currency Revenue(1) - 8.6% in Product Development -7.9% in Integrated Healthcare Services -Second sequential billion dollar service revenue quarter 8.4% 38.8% Diluted Adjusted EPS growth
  • 6. 6 $93bn Product Development Market(1) Attractive and Growing Market ~$200bn addressable market with growth of 5% - 8% per year from 2013 - 2016  $51bn Addressable Phase I-IV Clinical  $19bn Outsourced Phase I-IV Clinical ~37%  Outsourced Market penetration is estimated to increase by 200-300 basis points per year approaching 47% outsourced in 2017  The central lab market growth rate is estimated at 4.5% - 5% from 2013 – 2016 with an increase in test complexity $94bn(1,2) Integrated Healthcare Services Market  $16bn Outsourced ~17%  Market penetration is estimated to increase by 150-200 basis points per year  Broad customer interest in variabalizing cost  New product launches are expected to increase with the recent increase in NMEs; 27 in ‘13, 39 in ‘12, and 30 in ‘11 (1) Based on Company estimates (2) Includes market access, reimbursement, observational studies, comparative effectiveness research, health economics & outcomes research, and commercial consulting (3) Segment Income from Operations Approval Phase I Phase II Phase III Healthcare Delivery Product Development Commercial Product Development Services (93% of Operating Profit) (3) Integrated Healthcare Services (“IHS”) (7% of Operating Profit) (3) Phase IV Late Phase Interventional Project Management & Clinical Monitoring Clinical Trial Support (Central Lab, Biostatistics, Data Management, Technology, etc.) Product Development Consulting (Strategic Planning & Design) Commercial Focused Services Late Phase / Observational Other Healthcare Solutions Consulting, Market Access
  • 7. 7 Evolving Biopharma Landscape Growth, inefficiency and complexity play to Quintiles’ strength Higher NME Approvals Larger Pipelines R&D Spending Increasing Outsourcing Penetration Personalized Medicine Increasing Trial Complexity R&D spending grew ~1.5%4 in 2013 and is forecasted to grow 0%-2% through 20163 1 M. Allison, Reinventing clinical trials, Nature Biotechnology 30, no 1 (2012): 41-49; Median procedures calculated on a three year basis: 2000-2003 and 2008-2011 . 2 Decision Resources, November 2013. 3 Based on Company estimates. 4EvaluatePharma. 5 www.fda.gov. 6PharmaProjects, January 2014. Outsourcing is increasing by ~2 percentage points each year3 The median number of procedures per trial increased by 57% between 2003 and 20111 4,0606 drugs in the Phase I-III pipeline in 2013, a 19% increase over 2008 FDA approved 27 NMEs in 2013, 39 in 2012, and 30 in 2011. From 2006-2010, the average number of approvals was 225 Over 3,000 ongoing clinical trials involve a biomarker or predictive diagnostic 2 Industry Growth R&D Complexity Biopharma restructurings Trial Design Regulatory Market Access Commercial Pathways Scientific DepthMedical Expertise
  • 8. 8 Deep Customer Relationships Largest Backlog in Industry Providing Consistency, Sustainability and Diversification These Relationships Provide Durable Performance Today And Position Quintiles For Increases In Addressable Market Share Worked with all top 20 biopharma companies in each of last 11 years All of our top 25 key customers worked with both Quintiles segments: PD and IHS $100mm+ service revenues from at least 8 customers in each of past 6 years ~65% of service revenues outside of US ~51% of 2013 net new business from outside the Top 20 Pharma < 10% of revenues from largest customer – diverse customer base Worked with over 500 biopharma customers C-Level access and relationships
  • 9. 9 > Depth and breadth of service offerings enabled the win of 2 sole provider deals in 2013 Leader of innovative models The Leader in BioPharma Services Why We Win = Enhanced Value for Customers • Clearly differentiated service offerings > Improving probability of success > Provided services to develop or commercialize top 50 best selling biopharmaceutical and biologic products from 2012 • Deepest medical and therapeutic, statistical, and quantitative expertise in the industry > 950 medical doctors and 900 Ph.D.’s > 14 therapeutic centers of excellence • Personalized medicine > Solutions include the integration of biomarkers and genomics, with novel genomic pre- profiling • Focused on real-world cost effectiveness > Portfolio prioritization and market access consulting capabilities > 80+ risk-based monitoring trials across 20,000+ sites > ~3,200 employees in Global Delivery Network > Award winning technology Leader in remote (risk-based) monitoring > Implemented > 350 patient registries and post approval programs Leader in real-world data Leader in adaptive trial design
  • 10. 10 Product Development • Core Segment representing 77% of Consolidated Service Revenues and 93% of Segment Income from Operations(1) • Market leader in Product Development services > #1 in Clinical Development / #2 in Central Lab • Diversified customer portfolio across BioPharma segments with tailored segment solutions • Integrated offerings across services and platforms • Proactive Business Development > 1.30 book-to-bill ratio - highest in five sequential quarters > Strong RFP volumes > Evolution of integrated end to end partnership models > Strong wins across Large, Mid-size and Emerging Pharma Ph - I Ph - II Ph - III Ph-IIIB & IV Product Development Services Technology and Informatics Deep Science, Therapeutic, & Regulatory Expertise Globally Harmonized Best in Class Processes Novel Approaches to Development Global Workforce (1) For full year 2013. Accelerating pipelines using science, technology and global delivery
  • 11. 11 Integrated Healthcare Services • IHS Segment represents 23% of Consolidated Service Revenues and 7% of Segment Income from Operations(1) • IHS includes market leading solutions > One of the leading outsourced global contract pharmaceutical sales organization > One of the leading observational services organizations • Convergence within Healthcare > IHS solutions are aligned to capitalize on the evolving convergence of patient, payer and provider, solutions to leverage evidence-based insights into commercial strategies to provide an integrated approach • Thought Leadership in consulting and observational research • Three consecutive quarters of strong net new business Integrated Healthcare Services Offerings Commercial Services: • Contract Sales • Market Entry / Market Exit • Integrated Channel Management • Patient Engagement Services • Market Access & Commercialization Consulting • Medical Education Real-World and Late Phase Research: • Observational Studies • Product and Disease Registries • Comparative Effectiveness Studies Other Healthcare Solutions • Encore Integrated Healthcare Services Phase II & III Commercial Healthcare Delivery > 60mm De-identified patient records > 9mm Patients enrolled in registries > 450 Clinical Educators > 120 Launched products in US ~ 100% Field based resources trained on compliance programs Communications & Engagement Services: • Digital Patient Services • Brand & Scientific Communications (1) For full year 2013. Improving the probability of commercial success
  • 12. 12 Encore Real World Evidence Provides Improved Outcomes Rationale • Enhances provider relationships and access to population health market • Adds EMR and meaningful use capabilities • Natural supplement to Real World Late Phase business • Creates opportunity for future product & service offerings The Business • Experienced and proven management team • A leader in the EMR implementation and optimization with advisory consulting capabilities and emerging analytics capabilities in hospital quality metrics • Deep relationships with leading providers such as Tenet Healthcare, Carolinas Healthcare System, Carilion Clinic • 250 consultants Integration • Operating unit with Integrated Healthcare Services segment Transaction • Announced May 12, 2014 • Capability enhancing transaction
  • 13. 13 Quintiles An Attractive Investment Market leader in Product Development services Deep and diverse customer relationships with no customer contributing 10% or more of revenues Serve an attractive and growing market Geographically diversified revenue base Strong free cash flow First mover advantage with Clinical Development Informatics technology in the CRO industry Forward looking revenue visibility from largest backlog in industry Best in industry operating margins with a consistent focus on process and productivity leverage Long-term consistent financial performance
  • 15. 15 Adjusted Service Revenues Reconciliation Adjusted Service Revenues Reconciliation Year Ended December 31 (In Thousands) 2013 2012 2011 2010 Non-GAAP Adjusted Service Revenues: GAAP Service Revenues as Reported $3,808,340 $3,692,298 $3,294,966 $3,060,950 Deconsolidation of PharmaBio -– – – (64,198) Adjusted Service Revenues $3,808,340 $3,692,298 $3,294,966 $2,996,752
  • 16. 16 Adjusted EBITDA Reconciliation Adjusted EBITDA Reconciliation Year Ended December 31 (In Thousands) 2013 2012 2011 2010 Non-GAAP Adjusted EBITDA: GAAP Net Income as Reported $226,027 $176,631 $240,327 $165,255 Interest Expense, Net 119,571 131,304 105,126 137,631 Income Tax Expense 95,965 93,364 15,105 77,582 Depreciation and Amortization 107,504 98,288 92,004 84,217 Restructuring Costs 14,071 18,741 22,116 22,928 Impairment Charges – – 12,295 2,844 Incremental Share-based Compensation Expense – 13,637 2,553 – Bonus Paid to Certain Holders of Stock Options – 11,308 10,992 – Management Fees 27,694 5,309 5,213 5,159 Loss on Extinguishment of Debt 19,831 1,275 46,377 – Other (Income) Expense, Net (185) (3,572) 9,073 15,647 Equity in Losses (Earnings) from Unconsolidated Affiliates 1,124 (2,567) (70,757) (1,110) Deconsolidation of PharmaBio – – – (47,393) Adjusted EBITDA $611,602 $543,718 $490,424 $462,760 % of Adjusted Service Revenues 16.1% 14.7% 14.9% 15.4%
  • 17. 17 Adjusted Net Income Reconciliation Adjusted Net Income Reconciliation Year Ended December 31 (In Thousands) 2013 2012 2011 2010 Non-GAAP Adjusted Net Income: GAAP Net Income as Reported $226,027 $176,631 $240,327 $165,255 Net (Income) Loss Attributable to Noncontrolling Interests 564 915 1,445 (4,659) Restructuring Costs 14,071 18,741 22,116 22,928 Impairment Charges – – 12,295 2,844 Incremental Share-based Compensation Expense – 13,637 2,553 – Bonus Paid to Certain Holders of Stock Options – 11,308 10,992 – Management Fees 27,694 5,309 5,213 5,159 Loss on Extinguishment of Debt 19,831 1,275 46,377 – Interest Rate Swap Termination Fee – – 11,630 – Gain on Sale of Business Assets – – (74,880) – Deconsolidation of PharmaBio – – – (28,979) Tax Effect of Non-GAAP Adjustments (22,304) (18,885) (21,063) (752) Other Income tax Adjustments 3,057 – (66,000) – Adjusted Net Income $268,940 $208,931 $191,005 $161,796 % of Adjusted Service Revenues 7.1% 5.7% 5.8% 5.4%
  • 18. 18 Income Statement GAAP – Non-GAAP Reconciliation Three Months Ended March 31 (millions of dollars) Selling, General and Administrative Income from Operations Net Income Attributable to Quintiles Selling, General and Administrative Income from Operations Net Income Attributable to Quintiles As Reported $ 219.2 $ 141.3 $ 90.2 $ 199.3 $ 115.2 $ 48.3 Adjustments Restructuring Costs - 1.0 1.0 - 1.9 1.9 Management Fees - - - (1.3) 1.3 1.3 Tax Effect of Adjustments - - (0.3) - - (1.2) Other Income Tax Adjusments - - - - - 7.3 Adjusted Non-GAAP Basis $ 219.2 $ 142.3 $ 90.9 $ 198.0 $ 118.4 $ 57.6 % of Service Revenues 21.8% 14.2% 9.0% 21.4% 12.8% 6.2% 2014 2013 1Represents the Company’s change in its permanent reinvestment assertion during 2Q 2013 retroactively applied to1Q 2013 for the new estimated annual effective income tax rate. 1
  • 19. 19 Constant Currency Reconciliation Service Revenues and Income from Operations Service revenues exchange impact equals the current period service revenues for foreign currency denominated contracts recalculated at the prior period exchange rates less the current period service revenues, while the exchange rate impacts on expenses equals the current period expenses recalculated at the prior period exchange rates less the current period expenses at actual rates. The segment detail presented above excludes general corporate and unallocated expenses and restructuring costs. (millions of dollars) Consolidated Actual Exchange Impact Constant Actual Exchange Impact Constant Service Revenues 1,005.3$ (0.5)$ 1,005.8$ 8.4% 0.0% 8.4% Income from Operations 141.3$ 10.2$ 131.1$ 22.7% 8.9% 13.8% Adjusted Income from Operations 142.3$ 10.2$ 132.1$ 20.2% 8.6% 11.6% Adjusted Income from Operations Margin 14.2% 13.1% Product Development Service Revenues 770.8$ 3.7$ 767.1$ 9.1% 0.5% 8.6% Income from Operations 160.6$ 11.0$ 149.6$ 21.1% 8.3% 12.8% Income from Operations Margin 20.8% 19.5% Integrated Healthcare Services Service Revenues 234.5$ (4.2)$ 238.7$ 6.0% (1.9%) 7.9% Income from Operations 9.0$ (0.9)$ 9.9$ 43.2% (13.1%) 56.3% Income from Operations Margin 3.8% 4.1% Three Months Ended March 31 Year on Year Growth