2) Biological aspects of the teratogen effects- Describe the congenita.docx
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2) Biological aspects of the teratogen effects: Describe the congenital defects, disorders, adverse health outcomes, or neurobehavioral deficits associated with prenatal exposure to the teratogen. What organs or tissues are mostly affected? What are the most sensitive periods of prenatal development for the types of defects/outcomes described above? b. For one of the defects or adverse outcomes described above, describe a potential underlying biological mechanism for the teratogenic effects during development (usually these data come from animal studies). Be specific in your description of the biological mechanism (e.g. death of cells in a certain part of the brain leading to severe intellectual disability, decrease in nutrient transport across the placenta leading to very low birth weight, etc) .
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REFERENCES/READING
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Laureate Education, Inc. (Executive Producer). (2012d).
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Readings
Huether, S. E., & McCance, K. L. (2012).
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The document provides an overview of developmental psychology and the genetic and environmental influences on human development from conception through adulthood. It discusses genetic foundations including DNA, genes, alleles, and patterns of inheritance. It also examines environmental contexts such as family, socioeconomic status, and prenatal influences including teratogens. Key stages of prenatal development and characteristics of newborns are outlined.
Teratogen-Mutagen.ppt
This document discusses teratogenesis and mutagenesis. It defines teratology as the study of abnormalities in embryos and the agents that cause birth defects. Some effects of teratogens include limb reduction, organ absence or reduction in size, failure of structures to fuse, and developmental syndromes involving multiple anomalies. Teratogens can act by interfering with DNA replication, inhibiting enzymes, or causing oxidative stress. The principles of teratology are that susceptibility varies by species, developmental stage, and dose. Recognized teratogens include thalidomide, alcohol, vitamin A, and diethylstilbestrol. Mutagenesis involves spontaneous or induced genetic mutations from chemicals or radiation that can be passed to offspring or cause cancer
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Teratogens by Suyash Garg
Masters of science in Zoology from IGNTU Amarkantak M.P.
The technological advers on to the environment
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Chapter 2 biological foundations
1. Human development begins with fertilization and progresses through prenatal development stages including germinal, embryonic and fetal periods.
2. During these periods the major body systems and organs develop from the three primary germ layers as the embryo and fetus grow in the womb.
3. Prenatal development is influenced by genetic and environmental factors like nutrition, stress, maternal age and teratogens which can impact development and potentially cause birth defects or complications.
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NURS 6501:
To prepare:
Review this week’s media presentation with Dr. Terry Buttaro. Reflect on the importance of developing an in-depth understanding of pathophysiology.
Select a disorder from the following list:
Adrenal insufficiency (Addison’s disease)
Atherosclerosis
Cholelithiasis (gallstones)
Colon cancer
Cystic fibrosis
Hemophilia
Nephrolithiasis (kidney stones)
Osteoporosis
Parkinson’s disease
Tuberculosis
Select one of the following patient factors: genetics, gender, ethnicity, age, or behavior. Reflect on how that factor might impact your selected disorder, as well as potential associated alterations and symptoms.
Identify the pathophysiology of the associated alterations, including the normal and altered cellular function. Consider both intra- and extra-cellular changes that occur.
Post a 1 page discussion paper on a brief description of a patient scenario involving the disorder and the factor you selected. Explain how the factor might impact your selected disorder, as well as potential associated alterations and symptoms. Finally, explain the pathophysiology of the associated alterations, including changes in cellular function.
REFERENCES/READING
Media
Laureate Education, Inc. (Executive Producer). (2012d).
Introduction to advanced pathophysiology
. Baltimore, MD: Author.
Readings
Huether, S. E., & McCance, K. L. (2012).
Understanding pathophysiology
(Laureate custom ed.). St. Louis, MO: Mosby
Chapter 1, “Cellular Biology”, Chapter 2, “Genes and Genetic Diseases,
Chapter 3, “Altered Cellular and Tissue Biology”
.
Final coaching on coping with internet addiction counsellor s tool (1)
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