Nuclear Factor-Kappa B (NFkB) is a protein complex that regulates transcription of DNA and is activated during infections like tuberculosis. The study found that inhibiting NFkB activation in human macrophages decreased the survival of Mycobacterium tuberculosis bacteria inside the macrophages. Experiments showed that when NFkB was blocked, the macrophages could better control the M. tuberculosis infection.
Nuclear Factor-Kappa B (NFkB) is a protein complex that regulates transcription of DNA and is activated during infections like tuberculosis. The study found that inhibiting NFkB activation in human macrophages decreased the survival of Mycobacterium tuberculosis bacteria inside the macrophages. Experiments showed that when NFkB was blocked, the macrophages could better control the M. tuberculosis infection.
