Emma Gibbons conducted a study of indoor air quality in three modern office buildings in London. Continuous and passive monitoring was used to measure concentrations of pollutants like NO2 and PM2.5 both indoors and outdoors over periods of at least six months. The results showed outdoor pollutant levels were generally higher but indoor levels still exceeded WHO guidelines. Mechanically ventilated buildings with filtration had lower indoor PM2.5 levels. Potential mitigation strategies identified included improving outdoor air quality, optimizing building design and ventilation, and using air cleaning technologies. Next steps include further monitoring, analyzing results, and investigating smart ventilation and filtration options.
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Air monitoring legislation is getting stricter. At the beginning of 2018, France made air monitoring mandatory in schools and daycares and the EU top court issued one last warning to the UK, Poland and seven other member states to respect air pollutant limits. Clearly, air monitoring is at the table now and organizations are under pressure to monitor air pollutants continuously.
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B&ES Indoor Air Quality Group Meeting - RIBA LondonCamfil UK
The Building and Environmental Services Association Indoor Air Quality group was called to address increasing concern in the health implications of being exposed to poor indoor air quality.
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Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
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Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
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Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
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PRESENTATION ABOUT PRINCIPLE OF COSMATIC EVALUATION
12.15 Indoor air quality monitoring study in modern offices.pdf
1. Indoor air quality study in
modern office buildings
Emma Gibbons
October 2023
INSTITUTE FOR ENVIRONMENTAL DESIGN & ENGINEERING
Work has been supported by CIBSE, and the Engineering and
Physical Sciences Research Council (EPSRC).
Supervisors: Dr Marcella Ucci, Dr Sam Stamp
3. 01 Introduction
“Air Pollution is the top environmental risk to human health in the UK, and the fourth greatest threat to
public health after cancer, heart disease and obesity.” - Defra, Clean Air Strategy, 2019.
Public Health England, Guidance; Health matters: air pollution, Published 14 November 2018
https://www.gov.uk/government/publications/health-matters-air-pollution/health-matters-air-pollution
Indoor sources of air pollution
4. Research gaps
There is limited research into indoor
air pollutant concentrations and ingress
of ambient air pollution in city centre
offices.
Aim of study:
Understand how office buildings can be designed and operated
to reduce ingress of ambient air pollution, and what impact
building ventilation can have on indoor pollutant concentrations.
5. Case study building selection criteria:
• Buildings which are primarily offices.
• Buildings where the ventilation strategy of the
building is understood.
• Willingness of stakeholders (facility or building
managers) to be involved in the study.
• Buildings with different ventilation strategies.
• Buildings where monitoring can be carried out
indoors and outdoors simultaneously, for an
extended period (6 months plus).
02 Case study buildings
6. Case study building 1
• Six-storey office building in central London.
• Fully mechanically ventilated with no openable
windows.
• Air intake and air handling units (AHUs) located
at roof level.
• Air supplied to internal zones via active chilled
beams located in the ceilings.
• Building is located within an AQMA, declared
due to exceedances of PM10 (24-hr) and NO2
(annual) air quality objectives.
7. Case study building 2
• Ground floor office in central London.
• Fully mechanically ventilated with no
openable windows.
• Leaky façade.
• Air intake and air handling units (AHUs)
are located at basement level.
• Building is located within an AQMA,
declared due to exceedances of PM10
(24-hr) and NO2 (1-hr and annual) air
quality objectives.
8. Case study building 3
• Eight-storey office building in London.
• Naturally ventilated with openable
windows.
• Recently refurbished.
• Building is located within an AQMA,
declared due to exceedances of PM10
(24-hr) and NO2 (1-hr and annual) air
quality objectives.
9. • 22 air pollutants, plus comfort
parameters.
• Measurements using diffusive
(passive) sampling & continuous
monitoring methods.
• Continuous monitors co-located with
reference instruments prior to install.
• Continuous measurements taken
with 5 min averaging period.
• Discussions and semi-structured
interviews held with building teams.
03 Methodology
11. Monitoring locations
• First case study building - 30 monitoring locations (13 continuous and 17 passive)
• Second case study building - 11 monitoring locations (5 continuous and 6 passive)
• Third case study building - 16 monitoring locations (5 continuous and 11 passive)
• Measurements taken indoors and outdoors simultaneously, at a height representative
of exposure (indoors) at ground level, roof level and at air inlet locations (outdoors).
13. Outdoor NO2 concentrations higher than indoors, but
concentrations at all locations are greater than long-term WHO
guideline value of 10µg/m3.
Passive NO2 – Case study building 1
Increased winter-time NO2 concentrations,
observed indoors and outdoors.
14. Outdoor NO2 concentrations higher than indoors, but indoor concs still
higher than WHO guideline value.
Passive NO2 – Case study building 2
Increased winter-time NO2 concentrations
all locations.
15. Outdoor NO2 concentrations higher than indoors, and indoor
concentrations lower than in the mechanically ventilated buildings.
Passive NO2 – Case study building 3
Increased winter-time NO2 concentrations
at outdoor locations, but not indoors.
16. • Measured PM2.5 concentrations outdoors are higher than indoors.
• Positive impact of the in-line particulate filters in the mechanically ventilated building.
Continuous PM2.5 – Case study building 1
17. • Measured PM2.5 concentrations outdoors are higher than indoors – effective filtration.
• Leaky building shows increase in concentrations overnight.
Continuous PM2.5 – Case study building 2
Average PM2.5
concentration
(µg/m3) at all
monitoring
locations
Average PM2.5
concentration
(µg/m3) at indoor
locations
18. Potential mitigation strategies
Source control
• Building managers have less influence over outdoor pollutants.
• Some cities are doing more to improve ambient air pollution.
Building design
• Consideration of ventilation and AQ early in design phase e.g. location
of air intakes, ventilation style and set up, integrated filtration.
Smart ventilation
• Closing windows on high-pollution days can reduce occupant exposure
(Dutton et al., 2013, and Martins and Carrilho da Graça, 2018).
• Mechanical systems set to operate during certain time periods, avoiding
peak pollution events.
Air cleaning technologies
• Stand-alone units, such as air purifiers.
• In-line filters in mechanical systems.
• Carbon filters can reduce indoor concentrations of NO2, and filter
efficiency can be around 70-90% (Ginestet and Pugnet, 2006).
19. Present and
disseminate
findings
Air quality
monitoring in
further case
study buildings
Review
possible
mitigation
strategies
Continue to
analyse data
from case study
buildings
06 Next steps
Possible mitigation strategies to investigate: smart ventilation / air cleaning technologies.
Do you work in or know of a building which has hybrid ventilation,
CO2 controlled ventilation or NO2 filtration?
Are you looking to implement any mitigation strategies to improve indoor air quality?
20. Thank you, any questions?
Emma Gibbons, BSc (Hons), CEnv, MIAQM, MIEnvSc, PIEMA
The Bartlett School of Environment, Energy and Resources
UCL Institute for Environmental Design and Engineering
Email: emma.gibbons.20@ucl.ac.uk
INSTITUTE FOR ENVIRONMENTAL DESIGN & ENGINEERING