The document summarizes a study analyzing medical performance evaluation data for relicensure purposes. It discusses:
1) The General Medical Council in the UK requiring doctors to demonstrate they remain fit to practice through regular evaluations.
2) A project analyzing questionnaires completed by patients and colleagues to assess doctors' performance as part of the relicensure process.
3) The objectives of the study, which included examining the reliability and validity of the questionnaires, operational issues in collecting data, and how to analyze the data to identify doctors needing further review.
Lecture on Professionalism in Medicine, prepared and presented by Dr. Mohamed Alrukban and Dr. Ghaiath Hussein for 4th year medical students in the Medical Ethics Course on Monday Febraury 5, 2012.
Lecture on Professionalism in Medicine, prepared and presented by Dr. Mohamed Alrukban and Dr. Ghaiath Hussein for 4th year medical students in the Medical Ethics Course on Monday Febraury 5, 2012.
R&D Directions Webcast June Final[1]cmowen0206
Review a webcast presentation from experts from Vince and Associates Clinical Research, MidLands IRB, and Kendle for three presentations that delve into various aspects of clinical trial patient recruitment, from the perspectives of two prominent CROs and an AAHRPP-accredited independent review board. The presentations for this webinar are:
Phase I Patient Population Trials: Feasibility, Recruitment and Long-term Confinement
Speaker: Dr. Bradley Vince, D.O., Vince and Associates Clinical Research
Beyond Paper: Using Data-Driven Expertise to Enhance Patient Recruitment
Speaker: Jeffrey M. Zucker, Senior Director and Global Head, Patient Recruitment, Kendle
IRB Considerations in Proof-of-Concept Trials
Speaker: Kathy Chase, Pharm.D., IRB chair, MidLands IRB; Director, Provider Services, Cardinal Health - Pharmacy Solutions
R&D Directions Webcast June Final[1]cmowen0206
Review webcast presentation from MidLands IRB, Vince and Associates Clinical Research, and Kendle for three presentations that delve into various aspects of clinical trial patient recruitment, from the perspectives of two prominent CROs and an AAHRPP-accredited independent review board. The presentations for this webinar are:
IRB Considerations in Proof-of-Concept Trials
Speaker: Kathy Chase, Pharm.D., IRB chair, MidLands IRB; Director, Provider Services, Cardinal Health - Pharmacy Solutions
Phase I Patient Population Trials: Feasibility, Recruitment and Long-term Confinement
Speaker: Dr. Bradley Vince, D.O., Vince and Associates Clinical Research
Beyond Paper: Using Data-Driven Expertise to Enhance Patient Recruitment
Speaker: Jeffrey M. Zucker, Senior Director and Global Head, Patient Recruitment, Kendle
Some types of studies require unblinded personnel at the site and a matching unblinded monitoring and study management team. This presentation provides a little background on blinding and then reviews best practices for unblinding.
Feasibility Solutions to Clinical Trial Nightmaresjbarag
Slow patient recruitment and poor retention cause recurrent nightmares and perpetual problems often resulting in missing recruitment milestones. The cost of these delays represents hundreds of thousands of dollars for drug and device developers. By recognizing this issue, early detailed feasibility can provide planning and contingency solutions that are focused on reducing the impact of delayed recruitment. Furthermore understanding what motivates investigators and patients to actively participate in clinical studies and how patient recruitment strategies and materials can support all stakeholders to complete studies on time are critical aspects of clinical study delivery planning.
During this presentation, an experienced Premier Research feasibility and patient recruitment specialist, reviewed feasibility approaches to address protocol evaluation as well as addressed influences on country selection, site distribution and patient recruitment strategies to provide for more effective clinical trial planning and conduct.
For more information, go to http://www.premier-research.com.
R&D Directions Webcast June Final[1]cmowen0206
Review a webcast presentation from experts from Vince and Associates Clinical Research, MidLands IRB, and Kendle for three presentations that delve into various aspects of clinical trial patient recruitment, from the perspectives of two prominent CROs and an AAHRPP-accredited independent review board. The presentations for this webinar are:
Phase I Patient Population Trials: Feasibility, Recruitment and Long-term Confinement
Speaker: Dr. Bradley Vince, D.O., Vince and Associates Clinical Research
Beyond Paper: Using Data-Driven Expertise to Enhance Patient Recruitment
Speaker: Jeffrey M. Zucker, Senior Director and Global Head, Patient Recruitment, Kendle
IRB Considerations in Proof-of-Concept Trials
Speaker: Kathy Chase, Pharm.D., IRB chair, MidLands IRB; Director, Provider Services, Cardinal Health - Pharmacy Solutions
R&D Directions Webcast June Final[1]cmowen0206
Review webcast presentation from MidLands IRB, Vince and Associates Clinical Research, and Kendle for three presentations that delve into various aspects of clinical trial patient recruitment, from the perspectives of two prominent CROs and an AAHRPP-accredited independent review board. The presentations for this webinar are:
IRB Considerations in Proof-of-Concept Trials
Speaker: Kathy Chase, Pharm.D., IRB chair, MidLands IRB; Director, Provider Services, Cardinal Health - Pharmacy Solutions
Phase I Patient Population Trials: Feasibility, Recruitment and Long-term Confinement
Speaker: Dr. Bradley Vince, D.O., Vince and Associates Clinical Research
Beyond Paper: Using Data-Driven Expertise to Enhance Patient Recruitment
Speaker: Jeffrey M. Zucker, Senior Director and Global Head, Patient Recruitment, Kendle
Some types of studies require unblinded personnel at the site and a matching unblinded monitoring and study management team. This presentation provides a little background on blinding and then reviews best practices for unblinding.
Feasibility Solutions to Clinical Trial Nightmaresjbarag
Slow patient recruitment and poor retention cause recurrent nightmares and perpetual problems often resulting in missing recruitment milestones. The cost of these delays represents hundreds of thousands of dollars for drug and device developers. By recognizing this issue, early detailed feasibility can provide planning and contingency solutions that are focused on reducing the impact of delayed recruitment. Furthermore understanding what motivates investigators and patients to actively participate in clinical studies and how patient recruitment strategies and materials can support all stakeholders to complete studies on time are critical aspects of clinical study delivery planning.
During this presentation, an experienced Premier Research feasibility and patient recruitment specialist, reviewed feasibility approaches to address protocol evaluation as well as addressed influences on country selection, site distribution and patient recruitment strategies to provide for more effective clinical trial planning and conduct.
For more information, go to http://www.premier-research.com.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
Follow us on: Pinterest
Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stockrebeccabio
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stock
Telegram: bmksupplier
signal: +85264872720
threema: TUD4A6YC
You can contact me on Telegram or Threema
Communicate promptly and reply
Free of customs clearance, Double Clearance 100% pass delivery to USA, Canada, Spain, Germany, Netherland, Poland, Italy, Sweden, UK, Czech Republic, Australia, Mexico, Russia, Ukraine, Kazakhstan.Door to door service
Hot Selling Organic intermediates
Factory Supply Best Quality Pmk Oil CAS 28578–16–7 PMK Powder in Stock
Analysing medical performance evaluation data for relicensure purposes
1. Analysing medical
performance evaluation
data for relicensure
purposes
Ajit Narayanan
School of Computing and Mathematical
Sciences
Auckland University of Technology
1
2. Background
• In 1998 the General Medical Council (GMC),
which registers and regulates doctors practising
in the United Kingdom, determined that “all
doctors should be prepared to demonstrate at
regular intervals that they remain up to date and
fit to practise”
• Shortly afterwards, GMC proposed that
participation in such a process should become a
condition of continued registration
(“relicensure”/revalidation) of 200,000 doctors in
the UK
• GMC attracted by the use of questionnaires 2
completed by patients and colleagues as a
3. Overview of project
• Limited published evidence available regarding the
reliability, validity and effectiveness of relicensure
processes in the medical domain
• The overall aim was to conduct a large scale survey
of doctors undertaking multi-source feedback (MSF)
using the GMC patient and colleague questionnaires
• Between 1999 and 2003, GMC investigated various
questionnaires („tools‟) for use in MSF
• Preliminary work undertaken by Leeds University
Medical Education Unit (Sue Kilminster, Godfrey Pell,
Trudie Roberts: „Patient and Colleague
Questionnaires: Validation Report to the GMC,‟ May
2005)
3
4. Objectives of feasibility
project (2005-2011)
• In 2005, GMC commissioned the
Peninsula Medical School and an
independent survey company, CFEP, to
trial the tools with doctors in general
practice and then more widely across
different specialties.
• Are the MSF tools (patient
questionnaire, colleague questionnaire)
fit for purpose?
• Do the tools provide a first level 4
5. Specific objectives
• What are statistical properties of questionnaires in
terms of reliability and validity?
• What are operational issues involved in collecting
patient and colleague data?
• Once we have the data, how can we use it to help
identify doctors for further scrutiny?
• Overall, GMC/PMS/CFEP project deals with:
• how to collect the data
• how to analyse the data
• My role was one of the statistical consultants to the 5
GMC/PMS/CFEP project
6. Less than Don‟t
Poor
satisfactory
Satisfactory Good Very good
know
5 point Lickert
1 Clinical knowledge
2 Diagnosis
scale
Colleague
3 Clinical decision making questionnaire
4
Treatment
5
(including practical procedures)
Prescribing
questions
6 Medical record keeping
7
Recognising and working within
limitations 14 core questions
8
Keeping knowledge and skills up to
date
9
Reviewing and reflecting on own
performance on specific
10 Teaching (students, trainees, others) aspects of
11 Supervising colleagues
12
Commitment to care and wellbeing of
patients
professionalism
13
Communication with patients and
relatives
14 Working effectively with colleagues 4 global
15 Effective time management
Strongly
Disagree Neutral Agree
Strongly Don‟t
assessments
disagree agree know
16
I am confident that this doctor
respects patient confidentiality
17
I am confident that this doctor is
honest and trustworthy 1 summative
I am confident that this doctor‟s
18 performance is not impaired by ill
health
question (binary)
19 I am confident that this doctor is fit to practise medicine
Yes
No
Don‟t know
6
7. 4
How good was your doctor today at each of the following? (Please tick one box in each line)
Less than Does not
Poor Satisfactory Good Very good
satisfactory apply
a Being polite
Patient
b Making you feel at ease
questionnair
c Listening to you
e questions
d Assessing your medical condition
e Explaining your condition and treatment
f
Involving you in decisions about your
treatment
7 core
g Providing or arranging treatment for you
questions on
5 Please decide how strongly you agree or disagree with the following statements by ticking one box
in each line.
professionalis
Strongl
y Disagr
Neutral Agree
Strongl
y
Does not m
disagre ee apply
agree
e
I am confident that this doctor
a will keep information about me
confidential
2 global
b
I am confident that this doctor is
honest and trustworthy assessments
2 summative
6 I am confident about this doctor’s ability to provide care
Yes
No
assessments
(binary) 7
7 I would be completely happy to see this doctor again
Yes
No
8. Survey methods 1 (3rd cycle)
• Doctors from eleven sites in England and
Wales took part in the survey between Spring
2008 and September 2010.
• These included four acute hospital trusts, one
mental health trust, four primary care
organisations and one independent sector
(non-NHS) organisation
• Also, an anaesthetics department at a
university hospital NHS Trust contributed to
the main survey work.
8
9. Survey methods 2
• For most doctors, clinic receptionists or supporting
administrative staff were asked to distribute a PQ
pack to 45 consecutive patients (or carers) who are
consulting with the doctor.
• Doctors were requested to complete and return the
contact details (whenever possible including emails)
for 20 colleagues who were able to comment on their
practice.
• Normally, approximately half of those nominated
should be medical colleagues and the remainder
non-medical colleagues (e.g. nurses, allied health
professionals, administrative or managerial staff). 9
10. Third cycle (2010)
• 1065 doctors participated in both PQ
and CQ
• 908 doctors returned 22 or more PQ
responses (29284 PQs, mean 32.3 PQs
per doctor, median 36)
• 1050 doctors returned 8 or more CQ
responses (17012 CQs, mean 16.2 CQ
per doctor, median 17).
• 751 doctors provided sufficient returns
10
on both CQ and PQ
11. Reliability
• Cronbach α = 0.94 for CQ
• Cronbach α = 0.896 for PQ
• Other measures indicate that
questionnaires are highly reliable in that
respondents agreed on how to interpret
the items and how to use the scales to
assign ratings to subjects
11
12. Results for PQ
Left table: Unaggregated (raw patient scores)
Right table: Aggregated (patient scores when aggregated 12
by
doctor they are responding to)
14. Problem
•The mean scores for doctors (aggregated level) are
very high
•How does one identify potential under-performers
given the high ratings provided by raters?
•Since there are so few doctors who receive an adverse
rating on the summative items of CQ and PQ, the task
is to find patterns in the aggregated patient and
colleague scores that identify doctors for possible
further scrutiny and separate such doctors from those
who do not require further scrutiny.
•Also, it may be important to identify doctors whose 14
performance does not warrant placing them in the
15. Standards-based approach
• Even one standard deviation from the mean can result in a
score above the maximum possible (e.g. mean of 4.85 with
standard deviation of ±0.2 on a scale 1-5), so what is the
meaning of standard deviation in this context?
• Also, falling three standard deviations below the mean
may result in a doctor still obtaining a score that means
‘good’ (e.g. average 4.85 – 3*0.2=4.25).
• Data normalisation may lead to the accusation that, if the
questionnaires are highly reliable statistically, data is being
massaged for the political purpose of identifying doctors
for further scrutiny when, in fact, the original scores
indicate no cause for concern.
• Z-scores are representations of raw scores in terms of
standard deviations from the mean 15
16. Z-scores
ID item1 Item2 Item3 Item4 Item5 zitem1 zitem2 zitem3 zitem4 zitem5 below-1.96stds below -1std
1 3.78 3.50 3.67 3.78 3.60 -2.16 -2.26 -1.65 -1.27 -0.83 2 4
2 4.38 4.25 3.88 3.57 4.43 -0.31 -0.34 -1.12 -1.72 0.40 0 2
3 4.40 4.40 4.50 5.00 4.40 -0.23 0.04 0.46 1.36 0.35 0 0
4 4.58 4.56 4.53 4.50 4.44 0.32 0.46 0.54 0.28 0.41 0 0
5 4.79 4.63 4.59 4.33 4.71 0.97 0.61 0.69 -0.08 0.81 0 0
6 4.39 4.56 4.33 4.43 4.53 -0.27 0.46 0.04 0.13 0.55 0 0
7 4.75 4.75 4.75 4.60 4.64 0.85 0.93 1.10 0.50 0.70 0 0
8 4.42 4.08 3.93 4.00 3.92 -0.18 -0.79 -0.99 -0.79 -0.36 0 0
9 4.33 4.27 4.17 4.54 4.46 -0.44 -0.29 -0.38 0.37 0.44 0 0
10 4.94 4.85 4.83 4.93 2.50 1.45 1.18 1.31 1.22 -2.47 1 1
Synthetic database of 10 doctors with aggregated means
across 5 items (item1-item5), together with standardised z
scores for these items (zitem1-zitem5, where z represents
the standard deviation from the mean for that item). The
final two columns indicate the number of items below −1.96
standard deviations and below minus one standard
deviation from the mean, respectively. The original raw
scores of raters (Likert scale range 1-5) are not shown 16
17. Cluster analysis
• Cluster analysis explores and mines
data with the purpose of categorising
different samples into groups (clusters)
such that the degree of association
between two samples is maximal if they
belong to the same cluster and minimal
otherwise.
17
18. Meaning of clusters
• Ideally, all cases within a cluster have
maximum similarity while cases across
different clusters have a high degree of
dissimilarity
• Cases within a cluster have more in
common with each other than they do
with cases in other clusters.
18
19. Simple clustering example
Gene 1 Gene 2 Gene 3 Gene 4 Gene 5
0 1 0 0 0 Imagine that we have
Patient
1
4 patients and their
measurement on five
0 0 1 1 1 genes. Are there any
Patient
2 natural groupings
1 1 0 0 1
among these patients
Patient depending on their
3
gene profiles?
0 0 1 1 0
Patient
4
19
20. Step 1: calculate pairwise coefficients –
Workings P1/P2: 1+0+0+0+0=1/5=0.2
P1/P3: 0+1+1+1+0=3/5=0.6
Gene Gene Gene Gene Gene
1 2 3 4 5 P1/P4: 1+0+0+0+1=2/5=0.4
P2/P3: 0+0+0+0+1=1/5=0.2
0 1 0 0 0
Patien
P2/P4: 1+1+1+1+0=4/5=0.8 (ranked first in this step)
t1
P3/P4: 0+0+0+0+0=0.0
0 0 1 1 1
Patien Step 2: calculate pairwise coefficients, using P2+P4 as a
t2 „superpatient‟ –
1 1 0 0 1 P1/P2+P4: 1+0+0+0+0.5=1.5/5=0.3
Patien
t3 P3/P2+P4: 0+0+0+0+0.5=0.5/5=0.1
0 0 1 1 0 P1/P3 = 0.6 (as before) (ranked first in this step)
Patien
t4 Step 3: calculate pairwise coefficients, using P2+P4 as one
superpatient and P1+P3 as the second superpatient –
P1+P3/P2+P4: 0.5+0+0+0+0.5= 1/5=0.2 (final step)
0.0 Cluster dendogram
0.2 That is, two natural groupings
0.6
occur in the data, with P2 and
P4 forming one tight group
0.8 and P1 and P3 forming
1.0
another (looser) group. 20
P2 P4 P1 P3
21. Hierarchical cluster analysis
• HCA (agglomerative) clustering first assigns each
case to its own cluster, followed by an iterative
process whereby the two most similar clusters form a
new cluster until one overall cluster results.
• Clusters that are added to each other can consist of
single cases or multiple cases.
• The output is in the form of a taxonomy or
hierarchical tree („dendogram‟).
• Cases of increasing dissimilarity are aggregated at
various levels of the tree using a rescaled metric
(typically ranging from 1-25).
21
22. Cluster dendogram for
synthetic data
Tree indicates that cases
5-7 and 4-6-9 have more
in common with each
other than with any other.
Case 1 is a clear „outlier‟
in that it is clustered last.
Case 10 is also an outlier,
but not so much as Case
1
3 natural groupings plus 22
24. Application to CQ and PQ
• The aim here is to cluster satisfactory
doctors in a group, or in groups, that are
separate from the group, or groups, of
underperforming doctors based on
similarity and dissimilarity measures
calculated from their scores on
performative questionnaire items (18 for
CQ, 9 for PQ, 27 when combined).
24
25. 9 performance items from PQ
Left: full cluster dendogram for 908 doctors
using PQ data.
Right: expansion of bottom part of tree
identifying potentially under-performing doctors,
25
according to patients
26. 18
performance
items from
CQ
Left: full cluster dendogram for 1050 doctors using
CQ data.
Right: expansion of bottom part of tree identifying
potentially under-performing doctors, according to
26
colleagues
27. 27
performanc
e items from
both PQ and
CQ
Left: Full cluster diagram for 751 doctors using
both CQ and PQ data.
Right: expansion of bottom part of tree
identifying potential under-performing doctors, 27
according to both patients and colleagues
28. Conclusions
• Both the GMC patient and colleague
questionnaires represent instruments which
would provide a reasonable basis for the
collation of evidence regarding a doctor‟s
professional performance, according to our
reliability analysis so far.
• Raters currently are very reluctant to give
adverse ratings using the summative items.
• Other methods must be found that can tease
out of the data any concerns that raters have.
28
29. Conclusions
• Even if a doctor is ranked bottom (irrespective
of ranking method used), we must be careful
to interpret MSF results in the context of the
doctor‟s setting and specialty.
• There is no absolute threshold of
performance. Instead, the identification of
doctors for potential further scrutiny should be
supported by other evidence of performance,
given the financial, personal and professional
implications.
• Several medical councils have been following 29
30. Acknowledgements
Professor John Campbell (PMS*, Academic Lead)
Dr Suzanne Richards (Academic Project Manager, PMS)
Mr Andy Dickens (Research Fellow, PMS)
Associate Professor Michael Greco (Service Development Lead,
CFEP**)
Ms Jacqueline Hill (Research Fellow, PMS)
Dr Jeremy Hobart (Reader, PMS)
Professor Geoff Norman (Consultant)
Mr Martin Roberts (Statistician, Research Fellow, PMS)
Dr Christine Wright (Research Fellow, PMS)
*PMS: Peninsula Medical School at the Universities of Exeter and
Plymouth., UK. Now called Peninsula College of Medicine and
Dentistry.
**CFEP: Based at the Innovation Centre, University of Exeter, and in
Brisbane, Australia. 30