1 pts Which of the following is true? M1 macrophages are produced when activated T cells secrete Il. 4 and/or IL13. Alternatively activated macrophages carry out the bulk of phagocytosis seen in chronic inflammation. Lymphocytes are one of the main sources of IL6, which is one of the most important factors that cause chronic inftammation. Macrophages with abundant cytoplasm that resemble epithelium cells and often times fuse are the hallmark for acute inflammation. The wheal- and-flare reaction is caused predominantly by the action of eosinophils..