1. Nonproliferation & Verification — 25 Points Part A . What are the key factors that have motivated the development of biological weapons by states since its inception? What are the key factors that have led states to abandon biological weapon programs since the BWC came into effect? Explain why the verification protocol for the BWC collapsed in 2001. Explain why the U.S. opposed the protocol even to this day, after several presidents and their administrations have come and gone? Use historical and contemporary examples to support you argument. Part B . No new states have been added to public lists of countries with probable or knowledge of biological weapons programs in recent years. Since all of you have written that the BWC has "no teeth," to what do you attribute the restraint in biological weapons proliferation among states? Do you expect it to continue? Be sure to discuss the potential roles of strategy, science, arms control and norms in such decisions. 2. Policy & Intelligence — 25 Points Part A . What are the challenges faced by intelligence agencies including, but not limited to, inspection regimes in collecting and analyzing information about biological weapons programs conducted by states and by terrorist groups? Use historical and contemporary examples to support your analysis. Propose two recommendations for how the United States could improve its intelligence on biological warfare or bioterrorism programs. Part B . What are the three most important lessons learned relating to science, medicine, public health, law enforcement and homeland security from the use of biological agents by the Rajneesh cult in The Dalles, a small town in Oregon in 1984? To what extent do you believe current biodefense strategies, programs and policies reflect these lessons? 3. Terrorism — 35 Points Part A . In 2008, the Commission on the Prevention of Mass Destruction Proliferation and Terrorism wrote that, "Given the high level of know-how needed to use disease as a weapon to cause mass casualties, the United States should be less concerned that terrorists will become biologists and far more concerned that biologists will become terrorists." Explain with all the passion you can muster why you agree or disagree with that assessment. Part B. Compare the potential for a large-scale terrorist attack on the Washington D.C. Metro Transit system using (i) anthrax spores, (ii) sarin gas and (iii) a conventional suicide attack. What are the pros and cons of choosing one specific agent over another from the perspective of a terrorist group? Discuss each agent, how it works within the attack scenario and how first responders attempt to counter the attack. Part C . What would a non-state actor require to (i) obtain and (ii) successfully use the weapons described above in Part B? Are there significant differences between chemical and biological agents that could affect the level of difficulty for successful acquisition and use? ...