Isidro Salusky, MD “Writing the NIH K Award”
Distinguished Professor of Pediatrics at UCLA
Chief, Division of Pediatric Nephrology
Director, Clinical Translational Research Center
Associate Dean of Clinical Research
UCLA CTSI K Workshop - February 4, 2016
Learn to navigate through the possible career development awards (CDAs) available to you and which you should target.
Carol M. Mangione, MD, MSPH
Barbara A. Levey MD & Gerald S. Levey MD Endowed Chair
Professor of Medicine and Public Health at UCLA
Associate Director, UCLA Clinical and Translational Science Institute
Leader, Research Education, Training and Career Development Program
UCLA CTSI KL2 Award, New NIH Guidelines on Rigor & TransparencyUCLA CTSI
Explanation of the UCLA CTSI KL2 Award and the NIH guidelines. Provided by the UCLA Clinical and Translational Science Institute. More information is available at https://ctsi.ucla.edu/education/pages/kprogram
Presenter:
Mitchell D. Wong, MD, PhD
Professor of Medicine at UCLA
Executive Co-Director, Specialty Training and Advanced Research (STAR) Program
Director, UCLA CTSI KL2 Program
Learn to navigate through the possible K Awards / Career Development Awards (CDAs) available to you and which you should target. Provided by UCLA Clinical and Translational Science Institute.
Presenter:
Carol M. Mangione, MD, MSPH
Barbara A. Levey MD & Gerald S. Levey MD Endowed Chair
Professor of Medicine and Public Health at UCLA
Associate Director, UCLA Clinical and Translational Science Institute
Leader, UCLA CTSI Workforce Development
Presentation date: February 09, 2017
Writing the NIH K Award
Isidro B. Salusky, MD
Distinguished Professor of Pediatrics at UCLA
Chief, Division of Pediatric Nephrology
Director, Clinical Translational Research Center
Associate Dean of Clinical Research
Mitchell Wong, M.D. Ph.D.
Professor of Medicine
Executive Vice Chair for Research Training in the Department of Medicine.
Director of the CTSI KL2 Program,
Executive co-Director of the UCLA Specialty Training and Advanced Research (STAR) Program,
Co-Director of the UCLA NRSA Primary Care Fellowship
UCLA CTSI KL2 Award, New NIH Guidelines on Rigor & TransparencyUCLA CTSI
Explanation of the UCLA CTSI KL2 Award and the new NIH guidelines on Rigor & Premise.
Mitchell D. Wong, MD, PhD
Professor of Medicine at UCLA
Executive Co-Director, Specialty Training and Advanced Research (STAR) Program
Director, UCLA CTSI KL2 Program
Presentation date: February 09, 2017
Writing the NIH K Award (SF 424): K08-K23 Applications & Individual CDAsUCLA CTSI
Presented by:
Isidro B. Salusky, MD
Distinguished Professor of Pediatrics at UCLA
Chief, Division of Pediatric Nephrology
Director, Clinical Translational Research Center
Associate Dean of Clinical Research
Presentation from: February 09, 2017
UCLA CTSI K Workshop - February 4, 2016
Learn to navigate through the possible career development awards (CDAs) available to you and which you should target.
Carol M. Mangione, MD, MSPH
Barbara A. Levey MD & Gerald S. Levey MD Endowed Chair
Professor of Medicine and Public Health at UCLA
Associate Director, UCLA Clinical and Translational Science Institute
Leader, Research Education, Training and Career Development Program
UCLA CTSI KL2 Award, New NIH Guidelines on Rigor & TransparencyUCLA CTSI
Explanation of the UCLA CTSI KL2 Award and the NIH guidelines. Provided by the UCLA Clinical and Translational Science Institute. More information is available at https://ctsi.ucla.edu/education/pages/kprogram
Presenter:
Mitchell D. Wong, MD, PhD
Professor of Medicine at UCLA
Executive Co-Director, Specialty Training and Advanced Research (STAR) Program
Director, UCLA CTSI KL2 Program
Learn to navigate through the possible K Awards / Career Development Awards (CDAs) available to you and which you should target. Provided by UCLA Clinical and Translational Science Institute.
Presenter:
Carol M. Mangione, MD, MSPH
Barbara A. Levey MD & Gerald S. Levey MD Endowed Chair
Professor of Medicine and Public Health at UCLA
Associate Director, UCLA Clinical and Translational Science Institute
Leader, UCLA CTSI Workforce Development
Presentation date: February 09, 2017
Writing the NIH K Award
Isidro B. Salusky, MD
Distinguished Professor of Pediatrics at UCLA
Chief, Division of Pediatric Nephrology
Director, Clinical Translational Research Center
Associate Dean of Clinical Research
Mitchell Wong, M.D. Ph.D.
Professor of Medicine
Executive Vice Chair for Research Training in the Department of Medicine.
Director of the CTSI KL2 Program,
Executive co-Director of the UCLA Specialty Training and Advanced Research (STAR) Program,
Co-Director of the UCLA NRSA Primary Care Fellowship
UCLA CTSI KL2 Award, New NIH Guidelines on Rigor & TransparencyUCLA CTSI
Explanation of the UCLA CTSI KL2 Award and the new NIH guidelines on Rigor & Premise.
Mitchell D. Wong, MD, PhD
Professor of Medicine at UCLA
Executive Co-Director, Specialty Training and Advanced Research (STAR) Program
Director, UCLA CTSI KL2 Program
Presentation date: February 09, 2017
Writing the NIH K Award (SF 424): K08-K23 Applications & Individual CDAsUCLA CTSI
Presented by:
Isidro B. Salusky, MD
Distinguished Professor of Pediatrics at UCLA
Chief, Division of Pediatric Nephrology
Director, Clinical Translational Research Center
Associate Dean of Clinical Research
Presentation from: February 09, 2017
UCLA CTSI K Workshop
Learn to navigate through the possible career development awards (CDAs) available to you and which you should target.
Carol M. Mangione, MD, MSPH
Barbara A. Levey MD & Gerald S. Levey MD Endowed Chair
Professor of Medicine and Public Health at UCLA
Associate Director, UCLA Clinical and Translational Science Institute
Leader, UCLA CTSI Workforce Development
Presentation date: February 09, 2017
Navigating the NIH K Award Process (July 2015)UCLA CTSI
Carol M. Mangione, MD, MSPH
Barbara A. Levey MD & Gerald S. Levey MD Endowed Chair
Professor of Medicine and Public Health at UCLA
Associate Director, UCLA Clinical and Translational Science Institute
Program Leader, Research Education, Training and Career Development Program (CTSI-ED)
Grant Proposals (SF 424): K08-K23 Applications and Individual CDAsUCLA CTSI
UCLA CTSI K Workshop - February 4, 2016
Isidro B. Salusky, MD
Distinguished Professor of Pediatrics at UCLA Chief, Division of Pediatric Nephrology
Director, Clinical Translational Research Center
Associate Dean of Clinical Research
"NIH Electronic Grant Proposals (SF 424) – K23 and K08 Individual Career Develop Awards"
Isidro Salusky, MD
Distinguished Professor of Pediatrics
Division Chief, Pediatric Nephrology
Director, UCLA CTSI Clinical Translational Research Center
Associate Dean for Clinical Research
Navigating the NIH K Award Process (July 25, 2013)UCLA CTSI
Navigating the NIH K Award Process
Carol Mangione, MD, MSPH
Barbara A. Levey MD & Gerald S. Levey MD Endowed Chair
Professor of Medicine and Public Health at UCLA
Associate Director, UCLA Clinical and Translational Science Institute
Program Leader, Research Education, Training and Career Development Program
UCLA CTSI K Workshop - February 4, 2016
Mariko Ishimori, MD
Associate Health Sciences Clinical Professor of Medicine
Cedars-Sinai Medical Center CTSI Associate Leader UCLA Clinical & Translational Science Institute
Considerations in Applying for a K99 Award: the NIH "Pathway to Independence"...UCLA CTSI
Considerations in Applying for a K99 Award: the NIH "Pathway to Independence"
Presented by:
Christopher Evans, PhD
Professor of Psychiatry and Biobehavioral Sciences at UCLA
Director, Brain Research Institute
Presentation date: February 09, 2017
K99/R00 Awards - Pathways to IndependenceUCLA CTSI
UCLA CTSI K Workshop - February 4, 2016* (*updated Feb 1, 2017)
Christopher Evans, PhD
Professor of Psychiatry and Biobehavioral Sciences at UCLA
Director, Brain Research Institute
Carol Mangione, MD, MSPH “Navigating the NIH K Award Process”UCLA CTSI
Carol Mangione, MD, MSPH “Navigating the NIH K Award Process”
Barbara A. Levey MD & Gerald S. Levey MD Endowed Chair
Professor of Medicine and Public Health at UCLA
Associate Director, UCLA Clinical and Translational Science Institute
Program Leader, Research Education, Training and Career Development Program
Navigating the NIH K Award Process (2021)UCLA CTSI
Navigating the NIH K Award Process
Presented by Carol M. Mangione, MD, MSPH
Barbara A. Levey MD & Gerald S. Levey MD Endowed Chair
Professor of Medicine and Public Health at UCLA
Chief, Division of General Internal Medicine and Health Services Research
Associate Director, UCLA CTSI
Leader, UCLA CTSI Workforce Development
UCLA CTSI KL2 Resources
Presented by Mitchell D. Wong, MD, PhD
Professor of Medicine at UCLA
Executive Co-Director, Specialty Training and Advanced Research (STAR) Program
Director, UCLA CTSI KL2 Program
K99/R00 Awards - Pathways to IndependenceUCLA CTSI
Dr. Evans provides considerations in applying for a K99 Award. Provided by the UCLA Clinical and Translational Science Institute. More information at https://ctsi.ucla.edu/education/pages/edtools and https://ctsi.ucla.edu/education/pages/kprogram
Presenter:
Christopher Evans, PhD
Professor of Psychiatry and Biobehavioral Sciences at UCLA
Director, Brain Research Institute
UC Research Exchange (UC ReX) & Los Angeles Data Repository (LADR) UCLA CTSI
Learn more about the clinical data set tools, LADR and UC ReX available to UCLA CTSI, its partners and other UCs.
Marianne Zachariah
Administrator, Informatics Program
UCLA Clinical and Translational Science Institute
NIH Electronic Grant Proposals (SF 424)
K 08 - K - 23 Grant Applications
Individual Career Development Awards
Isidro B. Salusky, MD
Distinguished Professor of Pediatrics
Division Chief, Pediatric Nephrology
Director, Clinical Translational Research Center
Associate Dean for Clinical Research
David Geffen School of Medicine at UCLA
A Tactical Approach to Writing Your Grant Application (2020)UCLA CTSI
William Parks, PhD
Professor of Medicine at Cedars-Sinai Medical Center and UCLA
Associate Dean for Graduate Research Education
Scientific Director, Women’s Guild Lung Institute
Navigating the NIH K Award Process
Carol Mangione, MD, MSPH
Barbara A. Levey MD & Gerald S. Levey MD Endowed Chair
Professor of Medicine and Public Health at UCLA
Associate Director, UCLA Clinical and Translational Science Institute
Program Leader, Research Education, Training and Career Development Program
NIH Grant Proposals (SF 424): K08 - K23 Applications and Individual Career De...UCLA CTSI
Learn about NIH Grant Proposals (SF 424). Dr. Salusky discusses K08 - K23 applications and Individual Career Development Awards. Provided by the UCLA Clinical and Translational Science Institute. More information on K /CDA awards can be found at https://ctsi.ucla.edu/education/pages/edtools.
Presenter:
Isidro B. Salusky, MD
Distinguished Professor of Pediatrics at UCLA
Chief, Division of Pediatric Nephrology
Director, Clinical Translational Research Center
Associate Dean of Clinical Research
UCLA CTSI K Workshop
Learn to navigate through the possible career development awards (CDAs) available to you and which you should target.
Carol M. Mangione, MD, MSPH
Barbara A. Levey MD & Gerald S. Levey MD Endowed Chair
Professor of Medicine and Public Health at UCLA
Associate Director, UCLA Clinical and Translational Science Institute
Leader, UCLA CTSI Workforce Development
Presentation date: February 09, 2017
Navigating the NIH K Award Process (July 2015)UCLA CTSI
Carol M. Mangione, MD, MSPH
Barbara A. Levey MD & Gerald S. Levey MD Endowed Chair
Professor of Medicine and Public Health at UCLA
Associate Director, UCLA Clinical and Translational Science Institute
Program Leader, Research Education, Training and Career Development Program (CTSI-ED)
Grant Proposals (SF 424): K08-K23 Applications and Individual CDAsUCLA CTSI
UCLA CTSI K Workshop - February 4, 2016
Isidro B. Salusky, MD
Distinguished Professor of Pediatrics at UCLA Chief, Division of Pediatric Nephrology
Director, Clinical Translational Research Center
Associate Dean of Clinical Research
"NIH Electronic Grant Proposals (SF 424) – K23 and K08 Individual Career Develop Awards"
Isidro Salusky, MD
Distinguished Professor of Pediatrics
Division Chief, Pediatric Nephrology
Director, UCLA CTSI Clinical Translational Research Center
Associate Dean for Clinical Research
Navigating the NIH K Award Process (July 25, 2013)UCLA CTSI
Navigating the NIH K Award Process
Carol Mangione, MD, MSPH
Barbara A. Levey MD & Gerald S. Levey MD Endowed Chair
Professor of Medicine and Public Health at UCLA
Associate Director, UCLA Clinical and Translational Science Institute
Program Leader, Research Education, Training and Career Development Program
UCLA CTSI K Workshop - February 4, 2016
Mariko Ishimori, MD
Associate Health Sciences Clinical Professor of Medicine
Cedars-Sinai Medical Center CTSI Associate Leader UCLA Clinical & Translational Science Institute
Considerations in Applying for a K99 Award: the NIH "Pathway to Independence"...UCLA CTSI
Considerations in Applying for a K99 Award: the NIH "Pathway to Independence"
Presented by:
Christopher Evans, PhD
Professor of Psychiatry and Biobehavioral Sciences at UCLA
Director, Brain Research Institute
Presentation date: February 09, 2017
K99/R00 Awards - Pathways to IndependenceUCLA CTSI
UCLA CTSI K Workshop - February 4, 2016* (*updated Feb 1, 2017)
Christopher Evans, PhD
Professor of Psychiatry and Biobehavioral Sciences at UCLA
Director, Brain Research Institute
Carol Mangione, MD, MSPH “Navigating the NIH K Award Process”UCLA CTSI
Carol Mangione, MD, MSPH “Navigating the NIH K Award Process”
Barbara A. Levey MD & Gerald S. Levey MD Endowed Chair
Professor of Medicine and Public Health at UCLA
Associate Director, UCLA Clinical and Translational Science Institute
Program Leader, Research Education, Training and Career Development Program
Navigating the NIH K Award Process (2021)UCLA CTSI
Navigating the NIH K Award Process
Presented by Carol M. Mangione, MD, MSPH
Barbara A. Levey MD & Gerald S. Levey MD Endowed Chair
Professor of Medicine and Public Health at UCLA
Chief, Division of General Internal Medicine and Health Services Research
Associate Director, UCLA CTSI
Leader, UCLA CTSI Workforce Development
UCLA CTSI KL2 Resources
Presented by Mitchell D. Wong, MD, PhD
Professor of Medicine at UCLA
Executive Co-Director, Specialty Training and Advanced Research (STAR) Program
Director, UCLA CTSI KL2 Program
K99/R00 Awards - Pathways to IndependenceUCLA CTSI
Dr. Evans provides considerations in applying for a K99 Award. Provided by the UCLA Clinical and Translational Science Institute. More information at https://ctsi.ucla.edu/education/pages/edtools and https://ctsi.ucla.edu/education/pages/kprogram
Presenter:
Christopher Evans, PhD
Professor of Psychiatry and Biobehavioral Sciences at UCLA
Director, Brain Research Institute
UC Research Exchange (UC ReX) & Los Angeles Data Repository (LADR) UCLA CTSI
Learn more about the clinical data set tools, LADR and UC ReX available to UCLA CTSI, its partners and other UCs.
Marianne Zachariah
Administrator, Informatics Program
UCLA Clinical and Translational Science Institute
NIH Electronic Grant Proposals (SF 424)
K 08 - K - 23 Grant Applications
Individual Career Development Awards
Isidro B. Salusky, MD
Distinguished Professor of Pediatrics
Division Chief, Pediatric Nephrology
Director, Clinical Translational Research Center
Associate Dean for Clinical Research
David Geffen School of Medicine at UCLA
A Tactical Approach to Writing Your Grant Application (2020)UCLA CTSI
William Parks, PhD
Professor of Medicine at Cedars-Sinai Medical Center and UCLA
Associate Dean for Graduate Research Education
Scientific Director, Women’s Guild Lung Institute
Navigating the NIH K Award Process
Carol Mangione, MD, MSPH
Barbara A. Levey MD & Gerald S. Levey MD Endowed Chair
Professor of Medicine and Public Health at UCLA
Associate Director, UCLA Clinical and Translational Science Institute
Program Leader, Research Education, Training and Career Development Program
NIH Grant Proposals (SF 424): K08 - K23 Applications and Individual Career De...UCLA CTSI
Learn about NIH Grant Proposals (SF 424). Dr. Salusky discusses K08 - K23 applications and Individual Career Development Awards. Provided by the UCLA Clinical and Translational Science Institute. More information on K /CDA awards can be found at https://ctsi.ucla.edu/education/pages/edtools.
Presenter:
Isidro B. Salusky, MD
Distinguished Professor of Pediatrics at UCLA
Chief, Division of Pediatric Nephrology
Director, Clinical Translational Research Center
Associate Dean of Clinical Research
"Perspectives from the NIH Study Section"
Keith C. Norris, MD, FASN, FACP
Professor and Executive VP for Research and Health Affairs, Charles R. Drew University
Assistant Dean for Clinical and Translational Science, UCLA
Perspectives from the NIH Study Section
Keith C. Norris, MD, FASN, FACP
Professor and Executive VP for Research and Health Affairs, Charles R. Drew University
Assistant Dean for Clinical and Translational Science, UCLA
Finalizing and Reviewing the Health Research Proposal_Ashok.pptxAshok Pandey
To acquaint the participants with health research process, and
To enhance knowledge and skill of the participants for the development of health research proposal.
Protocol writing is a critical step in clinical research that involves developing a detailed plan or protocol for conducting a clinical trial. The protocol serves as a roadmap for the study, outlining the objectives, methodology, participant eligibility criteria, data collection procedures, and analysis plan. Here are key considerations when writing a protocol in clinical research:
Study Objectives and Research Questions: Clearly define the primary and secondary objectives of the study. State the research questions or hypotheses that the study aims to answer. This sets the foundation for the study design and data analysis plan.
Study Design: Describe the study design, such as randomized controlled trial (RCT), observational study, or non-inferiority trial. Specify the study phases (if applicable) and the allocation of study participants to different arms or groups. Justify the chosen design and explain how it aligns with the research objectives.
Participant Selection and Eligibility Criteria: Define the inclusion and exclusion criteria for participant selection. These criteria should be specific and relevant to the study population. Consider factors such as age, gender, medical history, disease severity, and previous treatments.
Interventions and Procedures: Describe the study interventions or treatments in detail. Specify the dosage, administration route, duration, and frequency of interventions. Document the study procedures, including data collection methods, laboratory tests, imaging techniques, and follow-up visits.
Sample Size and Power Calculation: Provide a rationale for the sample size estimation. Explain the statistical power calculation, specifying the desired effect size, significance level, and power. Justify the selected values and ensure that the sample size is sufficient to detect the intended effect or difference.
Data Collection and Management: Detail the data collection methods, including the use of case report forms (CRFs), electronic data capture (EDC) systems, or other data collection tools. Specify the variables to be collected, their measurement scales, and any scoring systems or questionnaires to be used. Describe the data management processes, data quality control procedures, and methods for ensuring data integrity.
Statistical Analysis Plan: Outline the statistical analyses that will be performed on the collected data. Describe the primary and secondary endpoints, statistical tests, and methods for handling missing data and outliers. Specify any interim analyses, subgroup analyses, or sensitivity analyses that will be conducted.
Ethical Considerations: Address ethical aspects, such as informed consent procedures, protection of participant confidentiality, and compliance with ethical guidelines and regulations. Discuss any potential risks and benefits to participants and how they will be mitigated. Outline the process for obtaining ethical approvals and reporting adverse events.
Create a detailed, integrated project charter to address a healt.docxvictorring
Create a detailed, integrated project charter to address a healthcare gap, need, or improvement at your practicum site.
Introduction
In NHS-FPX8040, you prepared a preliminary project charter. At that time, you may not have secured your practicum site or preceptor yet. Now that these are in place, in this course you will delve more deeply into creating a project charter appropriate for your practicum site’s needs. You may be able to use some of the project charter work you did in the previous course. At the same time, you may find you need to completely retool your work as it may no longer be appropriate for your practicum site. This is the changing nature of doctoral projects. As we learn more information, doctoral projects change. Your ability to manage this ambiguity and change will be critical to your successfully completing your doctoral program.
In this assessment, you will create a detailed, integrated project charter to address a healthcare gap, need, or improvement at your practicum site. You will need to obtain input from your practicum site about how you can help to meet their needs. After submitting your project charter, you will receive your faculty member’s feedback on your charter’s alignment with department objectives, academic rigor, coherency, and readiness for Institutional Review Board (IRB) submission.
Demonstration of Proficiency
By successfully completing this assessment, you will demonstrate your proficiency in the course competencies through the following assessment scoring guide criteria:
Competency 1: Create a project charter to address a clinical or organizational problem or take advantage of an opportunity for improvement within a health care setting.
Clearly describe the people who will be involved in and affected by a project.
Clearly describe an overview of all aspects of a project plan.
Clearly describe the strengths, weaknesses, opportunities, and threats related to a project plan.
Clearly describe the ethical considerations, constraints, external dependencies, and communication strategy of a project plan.
Clearly describe the outcome measures related to a project plan.
Clearly describe the data collection procedures related to a project plan.
Describe a project that could, within 8 to 12 weeks, produce a meaningful, sustainable change in practice or process that can be empirically evaluated, with minimal or no risk to participants or the organization.
Synthesize scholarly, authoritative evidence supporting each part of the project charter.
Competency 4: Address assessment purpose in a well-organized text, incorporating appropriate evidence and tone in grammatically sound sentences.
Write clearly and coherently, using communication style and vocabulary appropriate for scholarly work.
Correctly reference and cite scholarly and/or authoritative sources.
Preparation
To successfully prepare for this assessment, you will need to:
Ensure that your project aligns with your pract.
What Next: When You are not Funded on the First Round - 2023UCLA CTSI
CTSI R Workshop: What Next: When You are not Funded on the First Round.
Scott G. Filler, MD
Professor of Medicine at Lundquist Institute/Harbor-UCLA and UCLA
Leader, CTSI Pilot Translational and Clinical Studies Program
Co-Leader, CTSI KL2 Institutional Development Core
How to Write the “Specific Aims” Section - 2023UCLA CTSI
CTSI R Workshop: How to Write the “Specific Aims” Section of a Grant Application.
Tannaz Moin, MD, MBA, MSHS
Associate Professor of Medicine at UCLA
AssociateDirector, UCLA Specialty Training and Advanced Research (STAR) Program
How to Structure the “Approach” Section (Basic Science)UCLA CTSI
CTSI R Workshop: How to Structure the “Approach” Section of a Grant Application
Scott G. Filler, MD
Professor of Medicine at Lundquist Institute/Harbor-UCLA and UCLA
Leader, CTSI Pilot Translational and Clinical Studies Program
Co-Leader, CTSI KL2 Institutional Development Core
How to Craft the "Significance” & "Innovation" [Filler] - 2023UCLA CTSI
CTSI R Workshop: How to Craft the "Significance” & "Innovation" Sections of a Grant Application.
Scott G. Filler, MD
Professor of Medicine at Lundquist Institute/Harbor-UCLA and UCLA
Leader, CTSI Pilot Translational and Clinical Studies Program
Co-Leader, CTSI KL2 Institutional Development Core
How to Craft the "Significance” & "Innovation" - 2023UCLA CTSI
CTSI R Workshop: How to Craft the "Significance” & "Innovation" Sections of a Grant Application
William Parks, PhD
Professor of Medicine at Cedars-Sinai Medical Center and UCLA
Associate Dean for Graduate Research Education
Scientific Director, Women’s Guild Lung Institute
A Tactical Approach to Writing Your Grant Application (HSR) - 2023UCLA CTSI
CTSI R Workshop: A Tactical Approach to Writing Your Grant Application (HSR)
Tannaz Moin, MD, MBA, MSHS
Associate Professor of Medicine at UCLA
Associate Director, UCLA Specialty Training and Advanced Research (STAR) Program
A Tactical Approach to Writing Your Grant Application - 2023UCLA CTSI
CTSI R Workshop: A Tactical Approach to Writing Your Grant Application
William Parks, PhD
Professor of Medicine at Cedars-Sinai Medical Center and UCLA
Associate Dean for Graduate Research Education
Scientific Director, Women’s Guild Lung Institute
How to Write the “Specific Aims” Section of a Grant Application (Basic Scienc...UCLA CTSI
CTSI R Workshop: How to Write the “Specific Aims” Section of a Grant Application (Basic Science
Scott G. Filler, MD
Professor of Medicine at Lundquist Institute/Harbor-UCLA and UCLA
Leader, CTSI Pilot Translational and Clinical Studies Program
Co-Leader, CTSI KL2 Institutional Development Core
How to Anticipate and Plan for an R Grant Application - 2023UCLA CTSI
CTSI R Workshop: How to Anticipate and Plan for an R Grant Application.
Presented by Carol M. Mangione, MD, MSPH
Barbara A. Levey MD & Gerald S. Levey MD Endowed Chair
Chief, Division of General Internal Medicine and Health Services Research
Professor of Medicine and Public Health at UCLA
Leader, UCLA CTSI Workforce Development
NIH Loan Repayment Program (LRP) Info Session - 9/26/23UCLA CTSI
The UCLA CTSI and DGSOM Office of Physician Scientist Career Development held this webinar to provide information on the NIH Loan Repayment Program (LRP). This funding is designed to recruit and retain highly qualified health professionals into biomedical or biobehavioral research careers. The LRPs counteract financial pressure by repaying up to $50,000 annually of a researcher's qualified educational debt in return for a commitment to engage in NIH mission-relevant research.
Writing the NIH K Award – Research Plan
Presented by
Sumeet S. Chugh, MD
Price Professor and Associate Director, Smidt Heart Institute
Director, Division of Artificial Intelligence in Medicine
Cedars-Sinai Medical Center
Considerations in Applying for a K99 Award: the NIH "Pathway to Independence"...UCLA CTSI
Considerations in Applying for a K99 Award: the NIH "Pathway to Independence"
Presented by Christopher Evans, PhD
Professor of Psychiatry and Biobehavioral Sciences at UCLA
Co-Director, UCLA CTSI KL2 Program
Navigating the NIH K Award Process and Choosing Your Mentorship Team (2023)UCLA CTSI
Navigating the NIH K Award Process and Choosing Your Mentorship Team
Presented by
Carol M. Mangione, MD, MSPH
Barbara A. Levey MD & Gerald S. Levey MD Endowed Chair
Professor of Medicine and Public Health at UCLA
Chief, Division of General Internal Medicine and Health Services Research
Leader, UCLA CTSI Workforce Development
K Awards – Common Pitfalls and UCLA CTSI KL2 Resources (2023)UCLA CTSI
K Awards – Common Pitfalls and UCLA CTSI KL2 Resources
Presented by Elizabeta Nemeth, PhD
Professor of Medicine at UCLA
Director, UCLA Center for Iron Disorders
Co-Director, UCLA CTSI KL2 Program
Writing the NIH K Award – Candidate Information and Career Development Plan, ...UCLA CTSI
Writing the NIH K Award – Candidate Information and Career Development Plan,
How Reviewers Evaluate K Awards, and Common Critiques from NIH K Study Sections
Presented by O. Kenrik Duru, MD, MSHS
Professor of Medicine at UCLA
Investigator (Disparities), UCLA CTSI Special Populations
How to Anticipate and Plan for an R Grant Application. (2022)UCLA CTSI
Carol M. Mangione, MD, MSPH
Barbara A. Levey MD & Gerald S. Levey MD Endowed Chair
Chief, Division of General Internal Medicine and Health Services Research
Professor of Medicine and Public Health at UCLA
Leader, UCLA CTSI Workforce Development
K99 Award: the NIH "Pathway to Independence"UCLA CTSI
UCLA CTSI K Workshop - July 28, 2022
Considerations in Applying for a K99 Award: the NIH "Pathway to Independence" presented by Dr. Christopher Evans, PhD
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
A Strategic Approach: GenAI in EducationPeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
This Congress will not stand idly by and allow an environment hostile to Jewish students to persist. The House believes that your institution is in violation of Title VI of the Civil Rights Act, and the inability or
unwillingness to rectify this violation through action requires accountability.
Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
The House of Representatives will not countenance the use of federal funds to indoctrinate students into hateful, antisemitic, anti-American supporters of terrorism. Investigations into campus antisemitism by the Committee on Education and the Workforce and the Committee on Ways and Means have been expanded into a Congress-wide probe across all relevant jurisdictions to address this national crisis. The undersigned Committees will conduct oversight into the use of federal funds at MIT and its learning environment under authorities granted to each Committee.
• The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
• The Committee on Oversight and Accountability is investigating the sources of funding and other support flowing to groups espousing pro-Hamas propaganda and engaged in antisemitic harassment and intimidation of students. The Committee on Oversight and Accountability is the principal oversight committee of the US House of Representatives and has broad authority to investigate “any matter” at “any time” under House Rule X.
• The Committee on Ways and Means has been investigating several universities since November 15, 2023, when the Committee held a hearing entitled From Ivory Towers to Dark Corners: Investigating the Nexus Between Antisemitism, Tax-Exempt Universities, and Terror Financing. The Committee followed the hearing with letters to those institutions on January 10, 202
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdfTechSoup
In this webinar you will learn how your organization can access TechSoup's wide variety of product discount and donation programs. From hardware to software, we'll give you a tour of the tools available to help your nonprofit with productivity, collaboration, financial management, donor tracking, security, and more.
Instructions for Submissions thorugh G- Classroom.pptxJheel Barad
This presentation provides a briefing on how to upload submissions and documents in Google Classroom. It was prepared as part of an orientation for new Sainik School in-service teacher trainees. As a training officer, my goal is to ensure that you are comfortable and proficient with this essential tool for managing assignments and fostering student engagement.
Francesca Gottschalk - How can education support child empowerment.pptxEduSkills OECD
Francesca Gottschalk from the OECD’s Centre for Educational Research and Innovation presents at the Ask an Expert Webinar: How can education support child empowerment?
Macroeconomics- Movie Location
This will be used as part of your Personal Professional Portfolio once graded.
Objective:
Prepare a presentation or a paper using research, basic comparative analysis, data organization and application of economic information. You will make an informed assessment of an economic climate outside of the United States to accomplish an entertainment industry objective.
How to Make a Field invisible in Odoo 17Celine George
It is possible to hide or invisible some fields in odoo. Commonly using “invisible” attribute in the field definition to invisible the fields. This slide will show how to make a field invisible in odoo 17.
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
1. NIH Electronic Grant Proposals (SF 424)
K23 and K08
Individual Career Development Awards
Isidro B. Salusky, MD
Distinguished Professor of Pediatrics
Division Chief, Pediatric Nephrology
Program Director, UCLA CTSI Clinical Translational Research Center
2. K23: NIH Mentored Patient-Oriented
Research Career Development Award
• Used to support the career development of investigators
who are committed to a patient-oriented research agenda
• Size and duration of awards vary by proposed career
development projects and by programmatic and budgetary
specifics of participating ICs
• Candidate must devote a minimum of 9 person months (75%
of full-time professional effort) to specified research plan
• In general, candidates can request 3-5 years, depending on
individual needs to achieve research independence
• Awards are not renewable and are not transferable from one
PI to another
• All ICs utilize the K23 but prospective applicants should
contact the relevant NIH staff for IC-specific information
3. K08: NIH Mentored Clinical Scientist
Research Career Development Award
• Intensive, supervised research experience in the fields of
biomedical and behavioral research, including translational
research
• Participating ICs vary in programmatic and budgetary
specifics, and in size and duration of awards
• Candidate must devote a minimum of 9 person months (75%
of full-time professional effort) to specified research plan
• In general, candidates can request 3-5 years, depending on
individual needs to achieve research independence
• Awards are not renewable and are not transferable from one
PI to another
• Not all ICs utilize the K08 so prospective applicants should
contact the relevant NIH staff for IC-specific information on
restrictions
4. K23/K08 Application Outline
• Electronic template system (UCLA Cayuse) for online fill-in of
Cover Components and other SF 424 “form pages,” e.g.,
institutional and candidate information, other senior/key
personnel, project/performance site locations, budget data,
Checklist
• Project Summary/Abstract: Candidate, Environment, and
Research (1 page maximum, including the candidate's
immediate and long-term career goals, key elements of the
research career development plan, and description of the
research project)
• Project Narrative (Relevance Statement, 2-3 sentences, no
jargon)
• Facilities and Other Resources: Documentation of key
resources for the proposed research, training, career
development
5. K23/K08 Application Outline (cont)
• Specific Aims (1 page)
• Career Development Plan Sections: Candidate's Background,
Career Goals, and Objectives; Career Development/Training
Activities during Award Period; Training in the Responsible
Conduct of Research + Research Strategy Sections:
Significance, Innovation, Approach = 12 pages total (including
figures, tables, graphs, etc.)
• Bibliography and Literature Cited
• Human Subjects Sections: Protection of Human Subjects,
Inclusion of Women and Minorities, Targeted/Planned
Enrollment Table, Inclusion of Children
• Other Research Plan Sections: Vertebrate Animals, Select
Agent Research, Consortium/Contractual Arrangements,
Resource Sharing Plan
6. K23/K08 Application Outline (cont)
• Cover Letter (obligatory)
• Letters of Reference (minimum 3, maximum 5): due by the
application receipt deadline date
• Statements of Support from Mentor, Co-Mentors, Consultants,
Contributors
• Appendix (optional)
7. K23/K08: NIH Mentored Research
Career Development Award
SPECIAL REQUIREMENT: Mentor(s)
• Applicant must name a primary sponsor/mentor, who
together with the candidate is responsible for the planning,
direction, and execution of the career development
program.
• The mentor should be recognized as an accomplished
investigator in the proposed program and have a track
record of success in training similar investigators.
• The mentor should have sufficient independent support to
cover the costs of the proposed project in excess of the
allowable costs of this award.
• Candidates may also nominate co-mentors as appropriate
to the goals of the specified research program.
8. K23/K08: NIH Mentored Research
Career Development Award
SPECIAL REQUIREMENT: Institutional Environment
• Demonstrate your institution’s strong, well-established
record of career development activities and faculty
qualified in biomedical, behavioral, or clinical-translational
research to serve as mentors.
• Demonstrate the institution’s commitment to your
development as a productive investigator and willingness
to allow the protected time needed to complete your career
development program .
• Describe a career development program that will maximize
the use of this environment, including available facilities
and resources.
9. K23/K08 Candidate Information and Career Development Plan
Candidate’s Background
• Describe your commitment to an academic career in patient-
oriented research for the K23 OR biomedical/behavioral
research for the K08.
• Describe your professional responsibilities in the grantee
institution and elsewhere and show their relation to the
proposed activities on the career award.
• Present evidence of your ability to interact and collaborate
with other scientists.
• Describe prior training and how it relates to your objectives
and long-term career plans.
10. K23/K08 Candidate Information and Career Development Plan
Candidate’s Background (cont.)
• Describe your research efforts to this point in your research
career, including publications and prior research interests
and experience.
• Provide evidence of your potential to develop into an
independent investigator.
• Include a statement that you will commit at least 9 person-
months (75% of full-time professional effort) to the research
program and related career development activities. The
mentor or department chair must agree and provide a
statement in the application documenting that this
percentage of your time will be protected.
11. K23/K08 Candidate Information and Career Development Plan
Career Goals and Objectives
Describe a systematic plan that
(1) shows a logical progression from prior research and
training experiences to the training and research
experiences that will occur during the career award period
and then to independent investigator status
(2) justifies the need for further career development to
become an independent investigator
(3) utilizes the relevant research and educational resources
of the institution
12. K23/K08 Candidate Information and Career Development Plan
Career Development/Training Activities
• You and your mentor(s) are jointly responsible for the preparation of
the Career Development Plan. A timeline is often helpful. The
sponsor/mentor may form an advisory committee to assist with the
development of the program of study or to monitor your progress
through the career development program.
• The didactic (if any) and the research aspects of the plan must be
designed to develop the necessary knowledge and research skills in
scientific areas relevant to your career goals. You must demonstrate
you have received training or will participate in courses such as data
management, epidemiology, study design (including statistics),
hypothesis development, drug development, as well as the legal and
ethical issues associated with research on human subjects.
• Describe your professional responsibilities/activities, including other
research projects, beyond the minimum required 75% effort
commitment to the K award. Explain how these
responsibilities/activities will help ensure career progression to
achieve independence as an investigator.
13. K23/K08 Candidate Information and Career Development Plan
Training in the Responsible Conduct of Research
• Applications must include a plan to obtain instruction in the responsible
conduct of research.
• Document prior instruction in responsible conduct of research during
your current career stage (including the date of last occurrence) and
propose plans to receive instruction in responsible conduct of research.
• Such plans must address five instructional components: format, subject
matter, faculty participation, duration of instruction, and frequency of
instruction.
• The plan may include career stage-appropriate, individualized
instruction or independent scholarly activities that will enhance your
understanding of ethical issues related to your specific research
activities and the societal impact of that research.
• The role of the sponsor/mentor in responsible conduct of research
instruction must be described.
14. K23/K08 Research Plan: Specific Aims and Research Strategy
Specific Aims and Research Strategy sections follow the R01
model:
SPECIFIC AIMS (1 page)
•What do you intend to do?
RESEARCH STRATEGY (12 pages, including Career Development Plan)
Significance
•What has already been done in the field(s) and why is the proposed project
important in the context of prior work?
Innovation
•What is novel about the proposed project and how will it advance the field(s)?
Approach
•How are you going to achieve the specific aims of the project?
15. Specific Aims
• One page limit
• One paragraph introduction to the topic: Broad enough to
provide background information yet narrow enough to
provide focus for the project
• State concisely the goals of the proposed research and
summarize the expected outcome(s), including the impact
that the results of the proposed research will exert on the
research field(s) involved
• List succinctly the specific objectives of the research
proposed, e.g., to test a stated hypothesis, create a novel
design, solve a specific problem, challenge an existing
paradigm or clinical practice, address a critical barrier to
progress in the field, or develop new technology
• Focus and rewrite/hone
16. K23/K08 Research Plan: Specific Aims and Research Strategy
Specific Aims and Research Strategy sections follow the R01
model:
SPECIFIC AIMS (1 page)
•What do you intend to do?
RESEARCH STRATEGY (12 pages, including Career Development Plan)
Significance
•What has already been done in the field(s) and why is the proposed project
important in the context of prior work?
Innovation
•What is novel about the proposed project and how will it advance the field(s)?
Approach
•How are you going to achieve the specific aims of the project?
17. Research Strategy: Significance (1-2 pages)
• Explain the importance of the problem or critical
barrier to progress in the field that the proposed
project addresses.
• Explain how the proposed project will improve
scientific knowledge, technical capability, and/or
clinical practice in one or more broad fields.
• Describe how the concepts, methods, technologies,
treatments, services, or preventative interventions
that drive this field will be changed if the proposed
aims are achieved.
18. Significance
• Outline the background for the current
proposal
• Critically evaluate current knowledge
Supporting information
Conflicting information
Your own data, if available
• Identify gaps in existing knowledge that the
project will fill
• Link to specific aims or hypotheses
• Link to broader, long-term objectives
19. Significance
• Outline the background
Not a general review
Select salient features and focus on key issues
Provide perspective
Develop concepts
• Evaluate current knowledge
Consider conflicting views and acknowledge
work that has already been done
Be knowledgeable
Be diplomatic
Be precise
20. Significance
• Make the task of the reviewer easy
Develop a consistent sequence or pattern for the
discussion of the various specific aims or
hypotheses
Carry this sequence on through the Innovation
and Approach sections of the Research
Strategy
Carefully consider the placement of tables and
figures
21. Research Strategy: Innovation (1/2 to 1 pages)
• Explain how the application challenges and seeks to shift
current research or clinical practice paradigms.
• Describe any novel theoretical concepts, approaches,
methodologies, instrumentation, or interventions to be
developed or used, and any advantage over existing
methodologies, instrumentation, or interventions.
• Explain any refinements, improvements, or new
applications of theoretical concepts, approaches,
methodologies, instrumentation, or interventions.
22. Innovation
• Identify key areas where information is missing and
innovation is needed to fill knowledge gaps
Focus the attention of the reviewer
- Make it interesting
- Sell the product
Provide new information, either your own or others
Offer new perspectives
• Describe how the specific aims or hypotheses will fill
gaps in our current knowledge
• Together, Specific Aims, Significance, and Innovation
should provide an integrated and compelling
justification for the project
23. Research Strategy: Approach (5-7 pages)
• Describe the overall strategy, methodology, and analyses to be used to
accomplish the specific aims of the project. Unless addressed
separately in the Resource Sharing Plan, include how the data will be
collected, analyzed, and interpreted as well as any resource sharing
plans as appropriate.
• Discuss potential problems, alternative strategies, and benchmarks for
success anticipated to achieve the aims.
• If the project is in the early stages of development, describe any
strategy to establish feasibility, and address the management of any
high-risk aspects of the proposed work.
• Point out any procedures, situations, or materials that may be
hazardous to personnel and precautions to be exercised. A full
discussion on the use of select agents should be included in the Select
Agents Research section of the application.
24. Approach
• Describe the work to be done to
Address each specific aim
Test each hypothesis
• Outline how each study or experiment will
address the specific aims or hypotheses
described previously
25. Approach
• Organization is important
• Follow a logical sequence
• Describe methods to be used
General (overview)
- Study design
- Lab procedures
- Statistical procedures
- Justify
Specific studies or experiments
- Technical / methodological issues
- Document
26. Approach
General Methods
• Clinical project
Measurement instruments
Study population
Recruitment
Longitudinal follow-up
• Laboratory project
Cell or tissue culture methods
Specific analytical procedures
• Precision and accuracy of methods
• Previous experience
27. Approach
Experimental Procedures
• Describe experiments in sufficient detail
How they are done
Data to be obtained
How data are analyzed
Results expected
Conclusions reached
- Expected findings
- Unexpected findings
- Alternative interpretations
- Additional studies
• Relate results and interpretation to specific
aims / hypotheses
28. Approach
Experimental Procedures
• To address Specific Aim #1
Experiment #1
Experiment #2
• To address Specific Aim #2
Experiment #3
Experiment #4
Experiment #5
30. New Application - Key Issues
• Can this person do the work?
Proven methods
Technical expertise
Resources available
Study population
- Access
- Follow-up
Background and experience
Publications
Collaborators
31. K23/K08 Research Plan: Specific Aims and Research Strategy
• Propose a research project that is consistent with your level of
research development and objectives of your career
development. The research description should demonstrate not
only the quality of your research thus far but also the novelty,
significance, creativity, and approach, as well as your ability to
carry out the research.
• While the focus of the K23 award is patient-oriented research,
complementary laboratory research directly related to patient-
oriented research may be proposed in the application, thereby
providing an opportunity for a career development experience
in translational research.
• The application must also describe the relationship between
your mentor’s research and your proposed research plan.
• If more than one mentor is proposed, their respective areas of
expertise and responsibility should be described.
32. K23/K08 Statements of Support
Statements by Mentor and Any Co-Mentors
•The application must include a statement from the mentor, providing
(1) information on his/her research qualifications and previous experience
as a research supervisor
(2) a plan that describes the nature of the direct supervision and mentoring
that will occur during the proposed award period, as aligned with the
Research Strategy
(3) a plan for your career progression to move from the mentored stage to
independent research investigator status during the project period of the
award, including identification of aspects of the proposed research that you
will be able to take into your independent position
(4) a plan for monitoring your research, publications, and progression
toward independence
(5) documentation of the availability of sufficient research support and
facilities for high-quality research
(6) description of courses, seminars, and opportunities for interaction with
other scientists and trainees, including training in career skills such as grant
writing and effective presentations
33. K23/K08 Statements of Support
Statements by Mentor and Any Co-Mentors (cont.)
•Similar information must be provided by any co-mentor (s). If more than one
co-mentor is proposed, the respective areas of expertise and responsibility of
each should be described. Co-mentors should clearly describe how they will
coordinate the mentoring of the candidate. If any of the co-mentors are not
located at the home institution, a statement regarding the modes and
frequency of communication with you should be provided.
•The primary mentor must agree to provide annual evaluations of your
progress as required in the annual progress report.
34. K23/K08 Statements of Support
Statement by Consultants and/or Contributors
• Signed statements must be provided by each
consultant/collaborator, confirming participation in the
project and describing their specific roles.
• Collaborators and consultants do not need to provide
biographical sketches, but each must clearly document
appropriate expertise in the proposed areas of
consulting/collaboration.
• Collaborators/consultants are generally not directly
involved in the development of the career of the
candidate as an independent investigator.
35. K23/K08 Cover Letter (Obligatory)
• Cover letter is only for internal use and will not be
shared with peer reviewers
• Must include the list of referees, with their names,
department affiliations, and institutions
• Also include the following information:
1. Application title.
2. Funding Opportunity (PA or RFA) title of the
NIH initiative
3. Request of an assignment (referral) to a
particular awarding component(s) or Scientific
Review Group (SRG)
4. List of individuals (e.g., competitors) who
should not review your application and why
5. Disciplines involved, if multidisciplinary
36. K23/K08 Letters of Reference
• Electronic submission of reference letters is a separate process
from submitting an application electronically. Reference letters
are submitted directly by the referees through the eRA
Commons; must be submitted NO LATER THAN application
submission due date.
• You must arrange to have at least 3 (but no more than 5) letters
of reference submitted on your behalf. The letters should be
from well-established scientists (referees) and should address
your qualifications and competence as well as your potential for
becoming an independent investigator. These letters should be
from individuals not directly involved in the application, but
who are familiar with your educational background, training,
and interests.
• Applications that are missing the required letters of reference
may be delayed in the review process or not accepted.
37. Essential Steps in
Patient-Oriented Research
• Identification of an appropriate topic
• Choosing the appropriate study design
• Definition of variables to be measured
• Designing a data form or questionnaire
• Data management and quality
techniques
• Analytic strategies
• Appropriate MENTOR
38. CRITERIA FOR GOOD
RESEARCH QUESTION
• Feasible Ethical
- Adequate number of subjects
- Adequate technical expertise
- Affordable in time and money
• Interesting Relevant
- To the investigator
• Novel
- Confirms or refutes previous findings
- Provides new findings
- Extends previous findings
39. MENTOR
• Experience
• Availability
• Interest to work
• Adequate resources: grant support
• The choice of one or two senior scientists is the
single most important decision