Mise-en-scene refers to everything that appears on screen and includes 6 key areas: colour, costume, props, set/location, blocking/performance, and lighting. The document provides examples of how these elements are used to convey meaning and create mood through characters' clothing, backgrounds, objects, and lighting techniques like high key and low key. Costumes, for instance, can suggest a character's social class and personality, while lighting can make an image appear more dramatic with shadows or lighter for comedy genres. Mise-en-scene allows filmmakers to visually tell stories through intentional design of what appears on screen.