Ulcerative colitis is and IBD , characterized by recurring episodes of inflammation of mucosal layer of the colon. UC is result from chronic agnimandhya.

1. A CLINICAL TRIAL TO EVALUATE THE EFFFICACY OF
PICCHAVASTHI IN REDUCING SIGNS AND SYMPTOMS
OF ULCERATIVE COLITIS
SIMI RAVINDRAN
AY888

2. Introduction
• Ulcerative colitis is and IBD , characterized by
recurring episodes of inflammation of mucosal
layer of the colon. UC is result from chronic
agnimandhya.

3. Aims and Objectives
• To evaluate the efficacy of Piccha vasthi in
reducing signs and symptoms of ulcerative
colitis.
• To make an Ayurvedic conceptual basis of
Ulcerative colitis.

4. Methods
• Research approach
• Out line of the study
• Extensive literary survey
• Clinical work
• Selection of cases

5. • Study design
The present study is an pre post clinical trial
without a control group. Mayo’s scoring system
,physical examination and necessary investigation
were used for selection.
Patients in the group were given kaidaryadi kasaya
for seven days along with astakshari gulika 125
grams bd. After that picchavasthi were conducted
on yoga Vasti protocol. totally 12 patients were
included in the study.

6. STUDY DESIGN
Inclusion Criteria
• Ulcerative colitis patients
diagnosed by colonoscopy
and biopsy
• Age between 18-60 years
• Both sex are included
• Patient willing to participate
Exclusion criteria
• Diseases other than
ulcerative colitis
• Age below 18 yrs and above
60 yrs
• Other severe debilitating
diseases
• Patients not willing for the
study
•

7. • Assessment were conducted before piccha vasthi,
immediately after vasthi ,15 days after vasthi,30 days
after vasthi.The result were recorded in specific
proforma and the efficacy was compared by statistical
analysis
• Reason for selecting study design
Ulcerative colitis is a disease with
relapse and remission and most of the patients were
under steroidal medications. Ulcerative colitis patients
seeking for Ayurvedic treatment were less compared
to other disease. Study were preliminary.so I took open
clinical trial for the study

8. • Time and duration of the study
The total period of the study was 18 months.For each patient
,thestudy period was 4 weeks with follow up.
• Treatment schedule
Patient were selected after satisfiying
the inclusion criteria.They were admitted in the IPsection .
after selecting the patients ,the investigator collected the base
linde data and periodic assessments After deepana and
pachana picchavasthi were administered in a yoga vasthi
protocol. Before administering vasthi assessment were taken,
immediately after yoga vasthi,15 days after vasthi and 4 weeks
after vasthi assessment were taken .

9. Ingredients

10. Contents and Quantity of
picchavasthi
• Makshika-120 ml
• Saindava-5 gm
• Yastimadu , Tagara-15 gm each
• Madhuyastyadi taila-120 ml
• Maha tiktaka grutha-120 ml
• Salmali putapaka mixed with
milk-240 ml
Anuvasana vasthi
• Madhuyastyadi thylam-240 ml

11. Results
• Considering the symptom increase
frequency of bowel, the treatments
highly significant with P<01 immediately
after Vasthi and after follow up period.
• Considering the symptom diarrhea, the
treatment is highly significant with P<01
immediately after vasthi and after follow
up period
• Considering the symptom anorexia the
treatment is highly significant with P<01
immediately after Vasthi and after follow
up period

12. • Considering the ulcerations in the rectum, the
treatment is highly significant with P<01
immediately after vasthi
• Retention time of Vasthi in increasing
statistically because of getting bala to gudha
and pakvasaya after vasthi.

14. • Alternative hypothesis is
significantly satisfied
• Nidhana khataka play a
vital role –ahara and vihara
• Ahara paaka ,dhathu
parinama and
dhathuposhana are the
main process derranged
ulcerative colitis.
• awareness ,and good
practice of pathyapathya
playes a vital role
•Passage of blood with
stool
•Passage of mucus with
stool
•Diarrhea
•Abdominal distention
•Anorexia
•Abdominal cramps
•Increase in hematological
values of Hb
Highly significant :

15. Acknowledgements
• I take this opportunity to sincerely thank
Dr.G.Vinodkumar(Rtd HOD, Dpt of PK, GAVC Tvm)
and Dr. Shantakumari.P.K who stood as a pillar
behind me through out the study duration.