Helminthic infections are caused by parasitic worms. Successful parasites live in and obtain nutrients from the host without killing it. The severity of disease depends on the parasite burden and host immune response. Parasites enter through ingestion, arthropod bites, or skin/mucous membrane penetration. Some parasites must migrate within the host to complete their lifecycle, but non-human parasites in humans often become dead-end infections. Mechanisms of evading the immune response include antigenic variation, intracellular infection, encystation, and camouflage. Tissue damage results from direct destruction, hypersensitivity reactions, or eosinophilia during migration. Helminths are classified as nematodes, trematodes