5-HT Melatonin Dopamine Noradrenaline Adrenaline

1. STUDY MATERIAL
ON
Amino Acid Metabolism
Presented By:
Ms. Sayali Dilip Powar
(M. Pharm )
Department of Pharmaceutical Chemistry,
@ Tatyasaheb Kore College of Pharmacy,
Warananagar3/24/2020 1
Significance of Biological Substances

2. Significance of biological substances:
5-HT
Melatonin
Dopamine
Noradrenaline
Adrenaline
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3. 5-HT
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5-hydroxytryptamine receptors or 5-
HT receptors or serotonin receptors
Serotonin receptors mediate both central and
peripheral control on numerous
physiological functions such as sleep/wake
cycle, thermoregulation, food intake,
locomotion, sexual behavior, gastrointestinal
motility, blood coagulation, and cardiovascular
homeostasis.

4. Melatonin
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Melatonin, a derivative of the amino acid
tryptophan
It is produced in humans other mammals,
birds, reptiles, and amphibians.
 In humans, melatonin plays an
important role in the regulation of sleep
cycles

5. Dopamine
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Dopamine- an important neurotransmitter in
the CNS, regulates various physiological and
pathological processes in the body
It functions both as a hormone and
a neurotransmitter, and plays several
important roles in the brain and body.

6. Adrenaline & Noradrenaline
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