Immunity to parasitic infections

3. Toxoplasma
Schistosoma
Trypanosoma
One of the biggest
challenges posed to the
immune response by
most parasites is their
complicated life cycle,
leading to changes in
antigenic structure and
location over time.
Therefore,
the most effective
immune response will
depend on the type of
organism, the location of
the
infection, and the life
cycle stage of the
parasite.

16. The response includes an IgE humoral
component (top) and a cell-mediated
component involving CD4 T cells
(bottom).
C = complement;
ECF = eosinophil chemotactic factor;
NCF = neutrophil chemotactic factor;
PAF = platelet-activating factor.