Ascites is the pathologic accumulation of fluid within the peritoneal cavity. It is the most common complication of cirrhosis and occurs in about 50% of patient with decompensated cirrhosis in 10 years. The development of ascites denotes the transition from compensated to decompensated cirrhosis. The main symptoms of ascites are a large belly and rapid weight gain. Other symptoms include: Swelling in your ankles. Shortness of breath. Digestive issues, such as bloating, abdominal pain, loss of appetite, indigestion and constipation. Back pain. Difficulty sitting. Fatigue.