SlideShare a Scribd company logo
1 of 45
Download to read offline
Dr Sunita Sharma,
Professor & Head, Dept Of Pathology,
LHMC, New Delhi
Case 1
• 50 yr female
• C/O low grade fever,
cough and weakness
-one month
• O/E No organomegaly
Hb 10.3 g/dl
RBC 5.37x106/µl
MCV 64.2 fl
MCH 19.2 pg
RDW 20.7%
Retic 1.5%
TLC 8.5x103/µl
Platelet count 149x103/µl
P/S in 10X & 40X
P/S in 100X
What is your probable diagnosis?
What are the further tests required ?
} 8 yr old, male
} Chief complaints:
◦ Fever for 10 days
◦ Pallor
◦ Jaundice
◦ passage of black colored urine
} On examination : febrile, mild hepatomegaly
Clinical Diagnosis?
CBC
Hb 7 g/dl
RBC 2.3x106/µl
Hematocrit 16.9%
MCV 79.3 fl
MCH 32.9 pg
MCHC 41.4 g/dl
RDW 18.1%
TLC 24.9 x103 µl
Platelet 520 x103 µl
Corrected reticulocyte count 3.0 %
Possible diagnosis??
• Serum bilirubin-5mg/dl (Indirect-4,
Direct-1)
• LDH-1625 U/L ,
• Urea: 101 mg/dl,
• Creatinine: 1.6mg/dl
• Urine: oliguria, cola coloured
Urine m/e
Direct antiglobulin test: Positive
(polyspecific)
Direct antiglobulin test: IgG - Negative
(monospecific) IgM – Negative
C3 - Positive
What is your diagnosis?
What additional test?
• A 1.5 yr old male child presented in 2018
with complaints of
- palpable mass in left upper abdomen,
- fever, cough and vomiting
• On examination:
_ pallor
- hepatosplenomegaly (2cm & 6 cm below
costal margin),
• No H/O bleeding, petechiae
Case 3
Clinical Diagnosis: ?
• CBC : Hb- 6.7 g/dl,
• TLC- 8.9x 103/μL,
• Platelet count- 180x103/μL
• Corrected Reticulocyte count - 3.89%
• S. Bilirubin: 1.1mg/dl
• Coombs’ test: Negative
• Osmotic fragility test: No tail of fragile cells
• Sickling Test: Negative
• Hb High Performance Liquid
Chromatography (Child & Parents) : Within
normal limit
What is your probable diagnosis?
What further test is required ?
He was intermittently transfused, however he had persistent
anaemia, thrombocytopenia and increasing splenic size
Bone marrow studies were advised to exclude myelofibrosis
What is your final diagnosis?
What further test is required ?
Ø A 7 year old female presented with high fever (102.4 F
) with chills & cough – for 5 days
Ø No hepatosplenomegaly
Ø CBC: Hb : 8.2 g/dl, TLC :,9600/Cu.mm, Platelet count
:1, 79,000/cu.mm, MCV : 80.2 fl, rest unremarkable
Ø DLC : P 51 L 40 E 01 M 08
Ø Chest x-ray –Lower lobe consolidation-Right lung
Ø Past history : Four similar episodes in the last two
years
What is your diagnosis?
What are the other inclusions seen
in leucocytes?
Dr M.C. Sharma,
Professor, Dept Of Pathology,
AIIMS, New Delhi.
} 29 year male
} Perianal growth
} Retrovirus positive
LCA
HMB45
} A 50-year-male
} Follow up case of CLL
} Generalized lymph adenopathy & Tonsillar
growth after one year
21-24279
Biopsy from Tonsil
CD3 CD20
CD5 CD23
} A 18- year- male
} Resident of Iraq
} Anterior mediastinal mass
} Post operative chemotherapy
S 2557-21
} A 18- year- male
} Resident of Iraq
} Anterior mediastinal mass
} Post operative chemotherapy
} After 6 months developed cervical
lympadenopathy
15138
LCA
SALL4
} 55 year female
} Pulmonary lesions
} Cervical lymphadenopathy
CD3
EBBR
CD20
CD138
THANK YOU

More Related Content

What's hot

BCC4: Jon Gatward on Liver Transplantation
BCC4: Jon Gatward on Liver TransplantationBCC4: Jon Gatward on Liver Transplantation
BCC4: Jon Gatward on Liver TransplantationSMACC Conference
 
Complications of chronic liver disease
Complications of chronic liver diseaseComplications of chronic liver disease
Complications of chronic liver diseaseSayed Zaki
 
Proteinuria dr onu em
Proteinuria   dr onu emProteinuria   dr onu em
Proteinuria dr onu emOnu Emmanuel
 
albumin use in SBP patients
albumin use in SBP patientsalbumin use in SBP patients
albumin use in SBP patientsHemat Elgohary
 
Grand rounds presentation lauren ritchey updated last
Grand rounds presentation lauren ritchey updated lastGrand rounds presentation lauren ritchey updated last
Grand rounds presentation lauren ritchey updated lastLaur7114
 
Case presentation 222
Case presentation  222Case presentation  222
Case presentation 222FarragBahbah
 
Sample collection, Preservation and its Estimation
Sample collection, Preservation and its EstimationSample collection, Preservation and its Estimation
Sample collection, Preservation and its EstimationMD Abdul Haleem
 
STUDY OF ASCITIC FLUID FOR DIAGNOSIS OF SPONTANEOUS BACTERIAL PERITONITIS (SB...
STUDY OF ASCITIC FLUID FOR DIAGNOSIS OF SPONTANEOUS BACTERIAL PERITONITIS (SB...STUDY OF ASCITIC FLUID FOR DIAGNOSIS OF SPONTANEOUS BACTERIAL PERITONITIS (SB...
STUDY OF ASCITIC FLUID FOR DIAGNOSIS OF SPONTANEOUS BACTERIAL PERITONITIS (SB...Earthjournal Publisher
 
Adrenal insufficiency
Adrenal insufficiencyAdrenal insufficiency
Adrenal insufficiencyJin-Yi Hsu
 
03 laboratory tests part 1
03 laboratory tests part 103 laboratory tests part 1
03 laboratory tests part 1jhonee balmeo
 

What's hot (20)

BCC4: Jon Gatward on Liver Transplantation
BCC4: Jon Gatward on Liver TransplantationBCC4: Jon Gatward on Liver Transplantation
BCC4: Jon Gatward on Liver Transplantation
 
Complications of chronic liver disease
Complications of chronic liver diseaseComplications of chronic liver disease
Complications of chronic liver disease
 
Proteinuria dr onu em
Proteinuria   dr onu emProteinuria   dr onu em
Proteinuria dr onu em
 
Hematologic emergency
Hematologic emergencyHematologic emergency
Hematologic emergency
 
albumin use in SBP patients
albumin use in SBP patientsalbumin use in SBP patients
albumin use in SBP patients
 
Plasma exchange in neurologic disease
Plasma exchange in neurologic diseasePlasma exchange in neurologic disease
Plasma exchange in neurologic disease
 
Immobilization Hypercalemia
Immobilization HypercalemiaImmobilization Hypercalemia
Immobilization Hypercalemia
 
Grand rounds presentation lauren ritchey updated last
Grand rounds presentation lauren ritchey updated lastGrand rounds presentation lauren ritchey updated last
Grand rounds presentation lauren ritchey updated last
 
Case presentation 222
Case presentation  222Case presentation  222
Case presentation 222
 
Sample collection, Preservation and its Estimation
Sample collection, Preservation and its EstimationSample collection, Preservation and its Estimation
Sample collection, Preservation and its Estimation
 
Gi bleed
Gi bleedGi bleed
Gi bleed
 
Hematuria - causes and evaluation
Hematuria - causes and evaluationHematuria - causes and evaluation
Hematuria - causes and evaluation
 
Clinical laboratory
Clinical laboratoryClinical laboratory
Clinical laboratory
 
Noon conference kaylee park
Noon conference kaylee parkNoon conference kaylee park
Noon conference kaylee park
 
Catastrophic APLA
Catastrophic APLACatastrophic APLA
Catastrophic APLA
 
STUDY OF ASCITIC FLUID FOR DIAGNOSIS OF SPONTANEOUS BACTERIAL PERITONITIS (SB...
STUDY OF ASCITIC FLUID FOR DIAGNOSIS OF SPONTANEOUS BACTERIAL PERITONITIS (SB...STUDY OF ASCITIC FLUID FOR DIAGNOSIS OF SPONTANEOUS BACTERIAL PERITONITIS (SB...
STUDY OF ASCITIC FLUID FOR DIAGNOSIS OF SPONTANEOUS BACTERIAL PERITONITIS (SB...
 
Hepatology 101
Hepatology 101Hepatology 101
Hepatology 101
 
Adrenal insufficiency
Adrenal insufficiencyAdrenal insufficiency
Adrenal insufficiency
 
Common liver problems for extern
Common liver problems for externCommon liver problems for extern
Common liver problems for extern
 
03 laboratory tests part 1
03 laboratory tests part 103 laboratory tests part 1
03 laboratory tests part 1
 

Similar to Slide Seminar OTPGP.pdf

Dr mohammed alkoddousi case
Dr mohammed alkoddousi   caseDr mohammed alkoddousi   case
Dr mohammed alkoddousi caseFarragBahbah
 
11. a case study on chronic alcoholic liver disease
11. a case study on chronic alcoholic liver disease11. a case study on chronic alcoholic liver disease
11. a case study on chronic alcoholic liver diseaseDr. Ajita Sadhukhan
 
Nephrotic syndrome.pptx
Nephrotic syndrome.pptxNephrotic syndrome.pptx
Nephrotic syndrome.pptxAklimaMotaleb1
 
Dr ahmed alkodousi case
Dr ahmed alkodousi   caseDr ahmed alkodousi   case
Dr ahmed alkodousi caseFarragBahbah
 
Renal cell carcinoma after kidney transplantation 2017
Renal cell carcinoma after kidney transplantation 2017Renal cell carcinoma after kidney transplantation 2017
Renal cell carcinoma after kidney transplantation 2017CHAKEN MANIYAN
 
a case presentation of SLE
a case presentation of SLEa case presentation of SLE
a case presentation of SLETanveer Fahim
 
RETROPERITONEAL TERATOMA
RETROPERITONEAL TERATOMARETROPERITONEAL TERATOMA
RETROPERITONEAL TERATOMAcaptullash
 
Dr ibrahim alawaad case
Dr ibrahim alawaad   caseDr ibrahim alawaad   case
Dr ibrahim alawaad caseFarragBahbah
 
Fistula recto vaginal infection perspective
Fistula recto vaginal   infection perspectiveFistula recto vaginal   infection perspective
Fistula recto vaginal infection perspectiveSoroy Lardo
 
MLT Clinical Case Study
MLT Clinical Case StudyMLT Clinical Case Study
MLT Clinical Case StudyAnneka Pierzga
 
Hemophagocytic Lymphohistiocytosis - HLH
Hemophagocytic Lymphohistiocytosis - HLHHemophagocytic Lymphohistiocytosis - HLH
Hemophagocytic Lymphohistiocytosis - HLHJedrek Wosik, MD
 
Dr ahmed shabaan case
Dr ahmed shabaan   caseDr ahmed shabaan   case
Dr ahmed shabaan caseFarragBahbah
 
Dr ibrahim alnaggar case
Dr ibrahim alnaggar   caseDr ibrahim alnaggar   case
Dr ibrahim alnaggar caseFarragBahbah
 
Celiac common presentation of a uncommon disease saved with date
Celiac common presentation of a uncommon disease  saved with dateCeliac common presentation of a uncommon disease  saved with date
Celiac common presentation of a uncommon disease saved with dateMuhammad Arshad
 
Case presentation dr yossef
Case presentation dr yossefCase presentation dr yossef
Case presentation dr yossefFarragBahbah
 

Similar to Slide Seminar OTPGP.pdf (20)

Ibrahim
IbrahimIbrahim
Ibrahim
 
CHARES.pptx
CHARES.pptxCHARES.pptx
CHARES.pptx
 
Dr mohammed alkoddousi case
Dr mohammed alkoddousi   caseDr mohammed alkoddousi   case
Dr mohammed alkoddousi case
 
11. a case study on chronic alcoholic liver disease
11. a case study on chronic alcoholic liver disease11. a case study on chronic alcoholic liver disease
11. a case study on chronic alcoholic liver disease
 
Nephrotic syndrome.pptx
Nephrotic syndrome.pptxNephrotic syndrome.pptx
Nephrotic syndrome.pptx
 
Dr ahmed alkodousi case
Dr ahmed alkodousi   caseDr ahmed alkodousi   case
Dr ahmed alkodousi case
 
Renal cell carcinoma after kidney transplantation 2017
Renal cell carcinoma after kidney transplantation 2017Renal cell carcinoma after kidney transplantation 2017
Renal cell carcinoma after kidney transplantation 2017
 
a case presentation of SLE
a case presentation of SLEa case presentation of SLE
a case presentation of SLE
 
RETROPERITONEAL TERATOMA
RETROPERITONEAL TERATOMARETROPERITONEAL TERATOMA
RETROPERITONEAL TERATOMA
 
Dr ibrahim alawaad case
Dr ibrahim alawaad   caseDr ibrahim alawaad   case
Dr ibrahim alawaad case
 
CPC
CPCCPC
CPC
 
Fistula recto vaginal infection perspective
Fistula recto vaginal   infection perspectiveFistula recto vaginal   infection perspective
Fistula recto vaginal infection perspective
 
Dr eslam osama case
Dr eslam osama   caseDr eslam osama   case
Dr eslam osama case
 
MLT Clinical Case Study
MLT Clinical Case StudyMLT Clinical Case Study
MLT Clinical Case Study
 
Hemophagocytic Lymphohistiocytosis - HLH
Hemophagocytic Lymphohistiocytosis - HLHHemophagocytic Lymphohistiocytosis - HLH
Hemophagocytic Lymphohistiocytosis - HLH
 
Dr ahmed shabaan case
Dr ahmed shabaan   caseDr ahmed shabaan   case
Dr ahmed shabaan case
 
Dr ibrahim alnaggar case
Dr ibrahim alnaggar   caseDr ibrahim alnaggar   case
Dr ibrahim alnaggar case
 
Celiac common presentation of a uncommon disease saved with date
Celiac common presentation of a uncommon disease  saved with dateCeliac common presentation of a uncommon disease  saved with date
Celiac common presentation of a uncommon disease saved with date
 
Charts.pptx
Charts.pptxCharts.pptx
Charts.pptx
 
Case presentation dr yossef
Case presentation dr yossefCase presentation dr yossef
Case presentation dr yossef
 

Recently uploaded

Jeremy Casson - An Architectural and Historical Journey Around Europe
Jeremy Casson - An Architectural and Historical Journey Around EuropeJeremy Casson - An Architectural and Historical Journey Around Europe
Jeremy Casson - An Architectural and Historical Journey Around EuropeJeremy Casson
 
SHIVNA SAHITYIKI APRIL JUNE 2024 Magazine
SHIVNA SAHITYIKI APRIL JUNE 2024 MagazineSHIVNA SAHITYIKI APRIL JUNE 2024 Magazine
SHIVNA SAHITYIKI APRIL JUNE 2024 MagazineShivna Prakashan
 
Roadrunner Lodge, Motel/Residence, Tucumcari NM
Roadrunner Lodge, Motel/Residence, Tucumcari NMRoadrunner Lodge, Motel/Residence, Tucumcari NM
Roadrunner Lodge, Motel/Residence, Tucumcari NMroute66connected
 
Deconstructing Gendered Language; Feminist World-Making 2024
Deconstructing Gendered Language; Feminist World-Making 2024Deconstructing Gendered Language; Feminist World-Making 2024
Deconstructing Gendered Language; Feminist World-Making 2024samlnance
 
FULL ENJOY - 9953040155 Call Girls in Mahipalpur | Delhi
FULL ENJOY - 9953040155 Call Girls in Mahipalpur | DelhiFULL ENJOY - 9953040155 Call Girls in Mahipalpur | Delhi
FULL ENJOY - 9953040155 Call Girls in Mahipalpur | DelhiMalviyaNagarCallGirl
 
Aminabad @ Book Call Girls in Lucknow - 450+ Call Girl Cash Payment 🍵 8923113...
Aminabad @ Book Call Girls in Lucknow - 450+ Call Girl Cash Payment 🍵 8923113...Aminabad @ Book Call Girls in Lucknow - 450+ Call Girl Cash Payment 🍵 8923113...
Aminabad @ Book Call Girls in Lucknow - 450+ Call Girl Cash Payment 🍵 8923113...akbard9823
 
Gomti Nagar & High Profile Call Girls in Lucknow (Adult Only) 8923113531 Esc...
Gomti Nagar & High Profile Call Girls in Lucknow  (Adult Only) 8923113531 Esc...Gomti Nagar & High Profile Call Girls in Lucknow  (Adult Only) 8923113531 Esc...
Gomti Nagar & High Profile Call Girls in Lucknow (Adult Only) 8923113531 Esc...gurkirankumar98700
 
FULL ENJOY - 9953040155 Call Girls in Uttam Nagar | Delhi
FULL ENJOY - 9953040155 Call Girls in Uttam Nagar | DelhiFULL ENJOY - 9953040155 Call Girls in Uttam Nagar | Delhi
FULL ENJOY - 9953040155 Call Girls in Uttam Nagar | DelhiMalviyaNagarCallGirl
 
Charbagh / best call girls in Lucknow - Book 🥤 8923113531 🪗 Call Girls Availa...
Charbagh / best call girls in Lucknow - Book 🥤 8923113531 🪗 Call Girls Availa...Charbagh / best call girls in Lucknow - Book 🥤 8923113531 🪗 Call Girls Availa...
Charbagh / best call girls in Lucknow - Book 🥤 8923113531 🪗 Call Girls Availa...gurkirankumar98700
 
FULL ENJOY - 9953040155 Call Girls in Burari | Delhi
FULL ENJOY - 9953040155 Call Girls in Burari | DelhiFULL ENJOY - 9953040155 Call Girls in Burari | Delhi
FULL ENJOY - 9953040155 Call Girls in Burari | DelhiMalviyaNagarCallGirl
 
Call Girl Service In Dubai #$# O56521286O #$# Dubai Call Girls
Call Girl Service In Dubai #$# O56521286O #$# Dubai Call GirlsCall Girl Service In Dubai #$# O56521286O #$# Dubai Call Girls
Call Girl Service In Dubai #$# O56521286O #$# Dubai Call Girlsparisharma5056
 
Hazratganj / Call Girl in Lucknow - Phone 🫗 8923113531 ☛ Escorts Service at 6...
Hazratganj / Call Girl in Lucknow - Phone 🫗 8923113531 ☛ Escorts Service at 6...Hazratganj / Call Girl in Lucknow - Phone 🫗 8923113531 ☛ Escorts Service at 6...
Hazratganj / Call Girl in Lucknow - Phone 🫗 8923113531 ☛ Escorts Service at 6...akbard9823
 
FULL ENJOY - 9953040155 Call Girls in Old Rajendra Nagar | Delhi
FULL ENJOY - 9953040155 Call Girls in Old Rajendra Nagar | DelhiFULL ENJOY - 9953040155 Call Girls in Old Rajendra Nagar | Delhi
FULL ENJOY - 9953040155 Call Girls in Old Rajendra Nagar | DelhiMalviyaNagarCallGirl
 
Call Girl in Bur Dubai O5286O4116 Indian Call Girls in Bur Dubai By VIP Bur D...
Call Girl in Bur Dubai O5286O4116 Indian Call Girls in Bur Dubai By VIP Bur D...Call Girl in Bur Dubai O5286O4116 Indian Call Girls in Bur Dubai By VIP Bur D...
Call Girl in Bur Dubai O5286O4116 Indian Call Girls in Bur Dubai By VIP Bur D...dajasot375
 
FULL ENJOY - 9953040155 Call Girls in Laxmi Nagar | Delhi
FULL ENJOY - 9953040155 Call Girls in Laxmi Nagar | DelhiFULL ENJOY - 9953040155 Call Girls in Laxmi Nagar | Delhi
FULL ENJOY - 9953040155 Call Girls in Laxmi Nagar | DelhiMalviyaNagarCallGirl
 
RAK Call Girls Service # 971559085003 # Call Girl Service In RAK
RAK Call Girls Service # 971559085003 # Call Girl Service In RAKRAK Call Girls Service # 971559085003 # Call Girl Service In RAK
RAK Call Girls Service # 971559085003 # Call Girl Service In RAKedwardsara83
 
Bridge Fight Board by Daniel Johnson dtjohnsonart.com
Bridge Fight Board by Daniel Johnson dtjohnsonart.comBridge Fight Board by Daniel Johnson dtjohnsonart.com
Bridge Fight Board by Daniel Johnson dtjohnsonart.comthephillipta
 
Bur Dubai Call Girls O58993O4O2 Call Girls in Bur Dubai
Bur Dubai Call Girls O58993O4O2 Call Girls in Bur DubaiBur Dubai Call Girls O58993O4O2 Call Girls in Bur Dubai
Bur Dubai Call Girls O58993O4O2 Call Girls in Bur Dubaidajasot375
 
FULL ENJOY - 9953040155 Call Girls in Shahdara | Delhi
FULL ENJOY - 9953040155 Call Girls in Shahdara | DelhiFULL ENJOY - 9953040155 Call Girls in Shahdara | Delhi
FULL ENJOY - 9953040155 Call Girls in Shahdara | DelhiMalviyaNagarCallGirl
 

Recently uploaded (20)

Jeremy Casson - An Architectural and Historical Journey Around Europe
Jeremy Casson - An Architectural and Historical Journey Around EuropeJeremy Casson - An Architectural and Historical Journey Around Europe
Jeremy Casson - An Architectural and Historical Journey Around Europe
 
SHIVNA SAHITYIKI APRIL JUNE 2024 Magazine
SHIVNA SAHITYIKI APRIL JUNE 2024 MagazineSHIVNA SAHITYIKI APRIL JUNE 2024 Magazine
SHIVNA SAHITYIKI APRIL JUNE 2024 Magazine
 
Roadrunner Lodge, Motel/Residence, Tucumcari NM
Roadrunner Lodge, Motel/Residence, Tucumcari NMRoadrunner Lodge, Motel/Residence, Tucumcari NM
Roadrunner Lodge, Motel/Residence, Tucumcari NM
 
Deconstructing Gendered Language; Feminist World-Making 2024
Deconstructing Gendered Language; Feminist World-Making 2024Deconstructing Gendered Language; Feminist World-Making 2024
Deconstructing Gendered Language; Feminist World-Making 2024
 
Bur Dubai Call Girls # 971504361175 # Call Girls In Bur Dubai || (UAE)
Bur Dubai Call Girls # 971504361175 # Call Girls In Bur Dubai || (UAE)Bur Dubai Call Girls # 971504361175 # Call Girls In Bur Dubai || (UAE)
Bur Dubai Call Girls # 971504361175 # Call Girls In Bur Dubai || (UAE)
 
FULL ENJOY - 9953040155 Call Girls in Mahipalpur | Delhi
FULL ENJOY - 9953040155 Call Girls in Mahipalpur | DelhiFULL ENJOY - 9953040155 Call Girls in Mahipalpur | Delhi
FULL ENJOY - 9953040155 Call Girls in Mahipalpur | Delhi
 
Aminabad @ Book Call Girls in Lucknow - 450+ Call Girl Cash Payment 🍵 8923113...
Aminabad @ Book Call Girls in Lucknow - 450+ Call Girl Cash Payment 🍵 8923113...Aminabad @ Book Call Girls in Lucknow - 450+ Call Girl Cash Payment 🍵 8923113...
Aminabad @ Book Call Girls in Lucknow - 450+ Call Girl Cash Payment 🍵 8923113...
 
Gomti Nagar & High Profile Call Girls in Lucknow (Adult Only) 8923113531 Esc...
Gomti Nagar & High Profile Call Girls in Lucknow  (Adult Only) 8923113531 Esc...Gomti Nagar & High Profile Call Girls in Lucknow  (Adult Only) 8923113531 Esc...
Gomti Nagar & High Profile Call Girls in Lucknow (Adult Only) 8923113531 Esc...
 
FULL ENJOY - 9953040155 Call Girls in Uttam Nagar | Delhi
FULL ENJOY - 9953040155 Call Girls in Uttam Nagar | DelhiFULL ENJOY - 9953040155 Call Girls in Uttam Nagar | Delhi
FULL ENJOY - 9953040155 Call Girls in Uttam Nagar | Delhi
 
Charbagh / best call girls in Lucknow - Book 🥤 8923113531 🪗 Call Girls Availa...
Charbagh / best call girls in Lucknow - Book 🥤 8923113531 🪗 Call Girls Availa...Charbagh / best call girls in Lucknow - Book 🥤 8923113531 🪗 Call Girls Availa...
Charbagh / best call girls in Lucknow - Book 🥤 8923113531 🪗 Call Girls Availa...
 
FULL ENJOY - 9953040155 Call Girls in Burari | Delhi
FULL ENJOY - 9953040155 Call Girls in Burari | DelhiFULL ENJOY - 9953040155 Call Girls in Burari | Delhi
FULL ENJOY - 9953040155 Call Girls in Burari | Delhi
 
Call Girl Service In Dubai #$# O56521286O #$# Dubai Call Girls
Call Girl Service In Dubai #$# O56521286O #$# Dubai Call GirlsCall Girl Service In Dubai #$# O56521286O #$# Dubai Call Girls
Call Girl Service In Dubai #$# O56521286O #$# Dubai Call Girls
 
Hazratganj / Call Girl in Lucknow - Phone 🫗 8923113531 ☛ Escorts Service at 6...
Hazratganj / Call Girl in Lucknow - Phone 🫗 8923113531 ☛ Escorts Service at 6...Hazratganj / Call Girl in Lucknow - Phone 🫗 8923113531 ☛ Escorts Service at 6...
Hazratganj / Call Girl in Lucknow - Phone 🫗 8923113531 ☛ Escorts Service at 6...
 
FULL ENJOY - 9953040155 Call Girls in Old Rajendra Nagar | Delhi
FULL ENJOY - 9953040155 Call Girls in Old Rajendra Nagar | DelhiFULL ENJOY - 9953040155 Call Girls in Old Rajendra Nagar | Delhi
FULL ENJOY - 9953040155 Call Girls in Old Rajendra Nagar | Delhi
 
Call Girl in Bur Dubai O5286O4116 Indian Call Girls in Bur Dubai By VIP Bur D...
Call Girl in Bur Dubai O5286O4116 Indian Call Girls in Bur Dubai By VIP Bur D...Call Girl in Bur Dubai O5286O4116 Indian Call Girls in Bur Dubai By VIP Bur D...
Call Girl in Bur Dubai O5286O4116 Indian Call Girls in Bur Dubai By VIP Bur D...
 
FULL ENJOY - 9953040155 Call Girls in Laxmi Nagar | Delhi
FULL ENJOY - 9953040155 Call Girls in Laxmi Nagar | DelhiFULL ENJOY - 9953040155 Call Girls in Laxmi Nagar | Delhi
FULL ENJOY - 9953040155 Call Girls in Laxmi Nagar | Delhi
 
RAK Call Girls Service # 971559085003 # Call Girl Service In RAK
RAK Call Girls Service # 971559085003 # Call Girl Service In RAKRAK Call Girls Service # 971559085003 # Call Girl Service In RAK
RAK Call Girls Service # 971559085003 # Call Girl Service In RAK
 
Bridge Fight Board by Daniel Johnson dtjohnsonart.com
Bridge Fight Board by Daniel Johnson dtjohnsonart.comBridge Fight Board by Daniel Johnson dtjohnsonart.com
Bridge Fight Board by Daniel Johnson dtjohnsonart.com
 
Bur Dubai Call Girls O58993O4O2 Call Girls in Bur Dubai
Bur Dubai Call Girls O58993O4O2 Call Girls in Bur DubaiBur Dubai Call Girls O58993O4O2 Call Girls in Bur Dubai
Bur Dubai Call Girls O58993O4O2 Call Girls in Bur Dubai
 
FULL ENJOY - 9953040155 Call Girls in Shahdara | Delhi
FULL ENJOY - 9953040155 Call Girls in Shahdara | DelhiFULL ENJOY - 9953040155 Call Girls in Shahdara | Delhi
FULL ENJOY - 9953040155 Call Girls in Shahdara | Delhi
 

Slide Seminar OTPGP.pdf

  • 1. Dr Sunita Sharma, Professor & Head, Dept Of Pathology, LHMC, New Delhi
  • 2. Case 1 • 50 yr female • C/O low grade fever, cough and weakness -one month • O/E No organomegaly Hb 10.3 g/dl RBC 5.37x106/µl MCV 64.2 fl MCH 19.2 pg RDW 20.7% Retic 1.5% TLC 8.5x103/µl Platelet count 149x103/µl
  • 3. P/S in 10X & 40X
  • 5. What is your probable diagnosis? What are the further tests required ?
  • 6. } 8 yr old, male } Chief complaints: ◦ Fever for 10 days ◦ Pallor ◦ Jaundice ◦ passage of black colored urine } On examination : febrile, mild hepatomegaly Clinical Diagnosis?
  • 7. CBC Hb 7 g/dl RBC 2.3x106/µl Hematocrit 16.9% MCV 79.3 fl MCH 32.9 pg MCHC 41.4 g/dl RDW 18.1% TLC 24.9 x103 µl Platelet 520 x103 µl Corrected reticulocyte count 3.0 % Possible diagnosis??
  • 8.
  • 9. • Serum bilirubin-5mg/dl (Indirect-4, Direct-1) • LDH-1625 U/L , • Urea: 101 mg/dl, • Creatinine: 1.6mg/dl • Urine: oliguria, cola coloured Urine m/e
  • 10. Direct antiglobulin test: Positive (polyspecific) Direct antiglobulin test: IgG - Negative (monospecific) IgM – Negative C3 - Positive
  • 11. What is your diagnosis? What additional test?
  • 12. • A 1.5 yr old male child presented in 2018 with complaints of - palpable mass in left upper abdomen, - fever, cough and vomiting • On examination: _ pallor - hepatosplenomegaly (2cm & 6 cm below costal margin), • No H/O bleeding, petechiae Case 3 Clinical Diagnosis: ?
  • 13. • CBC : Hb- 6.7 g/dl, • TLC- 8.9x 103/μL, • Platelet count- 180x103/μL • Corrected Reticulocyte count - 3.89%
  • 14. • S. Bilirubin: 1.1mg/dl • Coombs’ test: Negative • Osmotic fragility test: No tail of fragile cells • Sickling Test: Negative • Hb High Performance Liquid Chromatography (Child & Parents) : Within normal limit
  • 15. What is your probable diagnosis? What further test is required ?
  • 16. He was intermittently transfused, however he had persistent anaemia, thrombocytopenia and increasing splenic size Bone marrow studies were advised to exclude myelofibrosis
  • 17. What is your final diagnosis? What further test is required ?
  • 18. Ø A 7 year old female presented with high fever (102.4 F ) with chills & cough – for 5 days Ø No hepatosplenomegaly Ø CBC: Hb : 8.2 g/dl, TLC :,9600/Cu.mm, Platelet count :1, 79,000/cu.mm, MCV : 80.2 fl, rest unremarkable Ø DLC : P 51 L 40 E 01 M 08 Ø Chest x-ray –Lower lobe consolidation-Right lung Ø Past history : Four similar episodes in the last two years
  • 19.
  • 20. What is your diagnosis? What are the other inclusions seen in leucocytes?
  • 21. Dr M.C. Sharma, Professor, Dept Of Pathology, AIIMS, New Delhi.
  • 22. } 29 year male } Perianal growth } Retrovirus positive
  • 23.
  • 24.
  • 26. } A 50-year-male } Follow up case of CLL } Generalized lymph adenopathy & Tonsillar growth after one year
  • 29.
  • 31. } A 18- year- male } Resident of Iraq } Anterior mediastinal mass } Post operative chemotherapy
  • 33.
  • 34.
  • 35. } A 18- year- male } Resident of Iraq } Anterior mediastinal mass } Post operative chemotherapy } After 6 months developed cervical lympadenopathy
  • 36. 15138
  • 37.
  • 39.
  • 40. } 55 year female } Pulmonary lesions } Cervical lymphadenopathy
  • 41.
  • 42.
  • 43.