A CASE PRESENTATION ON ALCOHOLIC LIVER DISEASE

1. ALCOHOLIC LIVER DISEASE
Presented By
Hashim Syed Ali Abbas H
HT NO: 170312882029
Pharm-D 6th
Year
MESCO COLLEGE OF PHARMACY.

2. ALCOHOLOC LIVER DISEASE
• Alcoholic liver disease is damage to the liver and its
function due to alcohol abuse.
• Alcoholic liver disease occurs after years of heavy
drinking. Over time, scarring and cirrhosis can occur.
Cirrhosis is the final phase of alcoholic liver disease.
• Alcoholic liver disease does not occur in all heavy
drinkers. The chances of getting liver disease go up
the longer you have been drinking and more alcohol
you consume.

3. .
SYMPTOMS
There may be no symptoms, or symptoms may come on slowly, depending
on how well the liver is working. Symptoms tend to be worse after a period of
heavy drinking.
Early symptoms include:
•Fatigue and loss of energy
•Poor appetite and weight loss
•Nausea
•Small, red spider-like blood vessels on the skin
As liver function worsens, symptoms may include:
•Fluid buildup of the legs (edema) and in the abdomen (ascites)
•Yellow color in the skin, mucous membranes, or eyes (jaundice)
•Redness on the palms of the hands
•Confusion or problems thinking
•Pale or clay-colored stools

4. M MMUHUHUIH
Gender:
Age:
Admitted
date:
Male
55 years
13-3-2017
C/O Yellow discoloration of skin, less urination ,swelling of body, hard
stools,fatigue
O/E Conscious , icterus, pedel edema
PMH Jaundice since 1 month
SH Married, farmer, alcoholic since 3 years , smoker
date 1 2 3 4 5 6 7 8 9
pulse 80 89 88
BP(mm
hg)
110/70 120/80 120/8

5. DIAGNOSIS

6. Hematology
TEST RESULT N. VALUES
Fasting 95 70-110 mg/dl
Postprandial 140mg/dl
Serum urea 28 20-40 mg/dl
Serum creatine 0.9 0.9-1.3 mg/dl
Serum uric acid 3.5-7.2 mg/dl
Total cholesterol Up to 200 mg/dl
HDL 30-60 mg/dl
LDL Up to 100 mg/dl
Total bilurubin 31.77 0.3-1.2 mg/dl
Direct bilurubin 21 0-0.2 mg/dl
Indirect bilurubin 10 0.3-1.0 mg/dl
SGOT 226 Up to 35 IU/L
SGPT 74 Up to 45 IU/L
Troponin I
Troponin T
CK-MB
Na 132 136-145 meq/l
Test RESULT N. VALUES
Hb % 9.2 12-18g/dl
PCV 32-47 %
WBC count 9900 5000-
11000cells/cu.mm
P 71 40-75 %
L 34 20-50 %
E 0.2 1-6 %
M 2-10 %
Platelet 195000 1.5-4.5
lakhs/cu.mm
ESR 48 0-20 mm/hr
MCV 82-96 cu.mm
MCH 27-32 pg/cell

7. Test INFERENCE
albumin 2.6g/dl(3.4-5.2)
globulin 3.6(1.5-3.5g/dl)
USG abdomen Spleenomegaly, portal vein hypertension
.

8. TREATMENT

9. .
TRADE NAME GENERIC NAME DOSE R.O.A FRE
Q
INDICATION
Tab. Trental Pentoxifylline 400mg P/O tid ALD
Tab. Pantocid Pantoprazole 40 mg P/O Od PPI
Inj vit k Vit k 10mg I.V od ALD
Inj.Thiamine HCL thiamine 100 mg IV od ALD
Syp. Duphalac Lactulose 20 ml P.O Tid Constipation
Inj hepamerz L-ornithine,l
aspartate
5gm/10
ml
I.V bd Jaundice
Tab. Rifgut, rifaximine 400 mg Od ANTIBIOTIC
Tab.lasix furosemide 40mg b.d DIURETIC
• tab.ttb

10. .
• DAY 2:
CST
• DAY 3:
CST
• DAY 4:
CST

11. PREVENTION(LIFE STYLE MODIFICAION)
 What your body does not need
1. Avoid alcohol.
2. Avoid foods that contain trans fat.
3. Reduce Sodium intake.
 WHAT TO TAKE: 1. Eat foods high in potassium to offset salt
intake. Bananas, Kiwi, apricots, raisins, tomato puree, baked
or roasted potatoes, veal and nuts, will all assist in ridding the
body of excess sodium.
2. Enjoy light to moderate physical activity, such as walking,
swimming, gardening
3.Build up slowly to 30 to 60 minutes of activity, at least 4
times a week.
4. Avoid food poisoning by storing and preparing foods safely.
Wash your hands often.

12. .
• Chew on Fennel Seeds throughout the day (not to exceed 1 tsp!) to unclog
the liver. Add Turmeric to your meals . It is become a well known spice in
the medicinal world that whose powerful nutrients are known for healing
organs.
• Carbohydrates(grains, fruits and vegetables)
• Fat Healthy oils such as: Extra Virgin Olive, Canola oil, Avocado and Smart
Balance oils. Omega 3, 6 reduces the inflammation in the liver: Fish,
Walnuts, Flaxseed
• Protein: Fish (3 x’s / wk), Poultry, Lean Meat
• Salt, canned and processed foods must be limited.
• Focus on lower saturated fat choices with each meal.
• Drink 6 to 8 glasses of fluids every day.

13. .
THANK YOU