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Dr. M. A. Quazi
M.Pharm, Ph. D.
Resins
1
• Benzoin
2
• Guggul
3 • Ginger
4
• Asafoetida
5 • Colophony
6
• Myrrh
Contents
 any natural or synthetic organic compound consisting of a
noncrystalline or viscous liquid substance.
 Natural resins are typically fusible and flammable organic
substances that are transparent or translucent and are yellowish
to brown in colour.
 They are formed in plant secretions and are soluble in various
organic liquids but not in water.
 Resin formation occurs as a result of injury to the bark from
wind, fire, lightning, or other cause.
Introduction
 Synonyms:
 Gum Benjamin; Benzoinum; Benzoin; Luban (Hindi)
 Biological Source:
 Benzoin is obtained from the incised stem of Styrax benzoin,
Styrax paralleloneurus, Styrax tonkinensis, belonging to
family Styraceae.
 Geographical Source
 The trees are found in Sumatra, Malacca, Malaya, Java, and
Borneo.
Benzoin
 Cultivation & Collection
 In Sumatra the seeds are sown in rice fields.
 The rice plants provide protection to benzoin plants
during first year.
 After harvesting of the rice crop the trees are allowed to
grow.
 When they are 7 years old, three triangular wounds are
made in a vertical row.
 Tapping consists of making in each trunk three lines of
incisions which are gradually lengthened.
 The first secretion is very sticky and is rejected.
 A single tree yields about 10 kg of resin per year and is
completely exhausted by the 19th year of its life.
 Sumatra benzoin occurs in brittle masses consisting of
opaque, whitish, or reddish tears embedded in a
translucent, reddish-brown or greyish-brown, resinous
matrix.
 Odour, agreeable and balsamic,
 taste, slightly acrid.

 Chemical Constituents
 Sumatra Benzoin consists of free balsamic acid
(cinnamic and benzoic acids) (25%) and their esters.
 Uses
 Sumatra Benzoin possesses expectorant, antiseptic,
carminative, stimulant, and diuretic properties. It is
used in cosmetic lotions, perfumery
 Synonyms:
 Gumgugul, Salai-gogil.
 Biological Source:
 Guggal is a gumresin obtained by incision of the bark
of Commiphora mukul belonging to family Burseraceae.
 Geographical Source
 The tree is a small, thorny plant distributed throughout India.
 Each plant yields about one kilogram of the product, which is
collected in cold season.
Guggul
 Guggal occurs as viscid, brown tears; or in fragment
pieces, mixed with stem, piece of bark; golden yellow
to brown in colour.
 With water it forms a milk emulsion.
 It has a balsamic odour
 taste is bitter, aromatic.
 Guggal contains gum (32%), essential oil (1.45%),
 sterols (guggulsterols I to VI, β-sitosterol,
cholesterol, Z- and E-guggulsterone),
 sugars (sucrose, fructose),
 amino acids, α-camphorene, cembrene,
 flavonoids (quercetin and its glycosides),
 ellagic acid, myricyl alcohol, etc.
 Guggal significantly lowers serum triglycerides and
cholesterol as well as LDL and VLDL cholesterols
 is astringent, aritirheumatic, antiseptic, expectorant,
aphrodisiac, demulcent, and emmenagogue.
 Synonyms:
 Rhizoma zingiberis, Zingibere. Adrak
 Biological Source:
 Ginger consists of the dried rhizomes of the Zingiber
officinale belonging to family Zingiberaceae..
 Oleo resin
 Geographical Source
 It is mainly cultivated in West Indies, Nigeria, Jamaica, India,
Japan, and Africa.
Ginger
 Dark Brown
 Aromatic, Pungent
 Viscous liquid
 Cultivation and Collection
 Rhizomes (Fingers)
 Loamy soil
 Well drained soil
 Percolation
 Ginger contains 1 to 2% volatile oil, 5 to 8% pungent
resinous mass and starch.
 Uses
 Sore throat, hoarseness, and loss of voice are benefited
by chewing a piece of ginger.
 Ginger is used as an antiemetic, spasmolytic, aromatic
stimulant, carminative, condiment, and flavouring
agent.
 Synonyms:
 Devil’s dung; food of the gods; asafoda; asant; hing (Hindi).
 Biological Source:
 Asafoetida is an oleo-gum resin obtained as an exudation by
incision of the decapitated rhizome and roots
of Ferula asafoetida , F. foetida, F. rubricaulis , and
some other species of Ferula, belonging to family Apiaceae..
 Geographical Source
 The plant grows in Iran, Turkestan and Afghanistan (Karam
and Chagai districts).
Asafoetida
 Collection
 The plant is a perennial branching, 3 m high herb
possessing large schizogeneous ducts and lysigenous
cavities containing milky liquid. Upon exudation and
drying of the liquid, Asafoetida is obtained.
 For the collection of the drug the upper part of the root
is laid bare and the stem cut off close to the crown in
March–April.
 Removal of the exudation and exposure of fresh
surface proceeds until the root is exhausted.
 Asafoetida occurs as a soft solid mass or irregular
lumps or ‘tears’, sometimes almost semiliquid.
 Tears are rounded or flattened and about 5–30 mm in
diameter,
 grayish-white or dull yellow or reddish brown in
colour.
 Asafoetida has a strong garlic-like (alliaceous) odour
and a bitter, acrid and alliaceous taste.
 Asafoetida contains volatile oil (4–20%), resin (40–
65%), and gum (25%).
 Chemical Tests
 On trituration with water it produces a milky emulsion.
 The drug (0.5 g) is boiled with hydrochloric acid (5 ml)
for sometime. It is filtered and ammonia is added to the
filtrate. A blue fluorescence is obtained.
 To the fractured surface add 50% nitric acid. Green colour
is produced.
 To the fractured surface of the drug, add sulphuric acid (1
drop). A red colour is obtained which changes to violet on
washing with water.
 Uses
 Asafoetida is used as carminative, expectorant, antispas-
modic, and laxative
 Synonyms:
 Rosin, yellow resin; Abietic anhydride; colophony resin;
amber resin; resin; coloponium.
 Biological Source:
 Colophony is a solid residue left after distilling off the volatile
oil from the oleoresin obtained from Pinus palustris (long leaf
pine) and other species of Pinus such as P. pinaster, P.
halepensis, P. massoniana, P. tabuliformis, P.
carribacea ., belonging to family Pinaceae.
 Geographical Source
 The genus Pinus is widely found in United States, France,
Italy, Portugal, Spain, Greece, New Zealand, China, India
(Himalayan region)
Colophony
 Colophony occurs as translucent, hard, shiny, sharp,
pale yellow to amber fragments,
 fracture brittle at ordinary temperature,
 burns with smoky flame,
 slight turpentine-like odour and taste,
 melts readily on heating, density 1.07–1.09.
 It is insoluble in water but freely soluble in alcohol,
benzene, ether, glacial acetic acid, oils, carbon
disulphide, and alkali solutions.
 Colophony contains resin acids (about 90%), resenes,
and fatty acid esters. Of the resin acids about 90% are
isomeric α-, β-, and γ-abietic acids; the other 10% is a
mixture of dihydroabietic
 To a solution of powdered resin (0.1 g) in acetic acid
(10 ml) one drop of conc. Sulphuric acid is added in
a test tube. A purple colour, readily changing to
violet, is formed.

 2. To a petroleum ether solution of powdered
Colophony twice its volume of dilute solution of
copper acetate is shaken. The colour of the
petroleum ether layer changes to emerald-green due
to formation of copper salt of abietic acid.
 Colophony is used as stiffening agent in ointments,
adhesives, plasters and cerates and as a diuretic in
veterinary medicine.
 Commercially it is used to manufacture varnishes,
printing inks, cements, soap, sealing wax, wood
polishes, floor coverings, paper, plastics, fireworks, tree
wax, rosin oil, and for water proofing cardboard.
 Synonyms:
 Gum-resin Myrrh; Gum Myrrh; Arabian or Somali Myrrh;
Myrrha.
 Biological Source:
 Myrrh is an oleo gum-resin obtained from the stem
of Commiphora molmol or C. abyssinica or other species of
Commiphora, belonging to family Burscraceae.
 Geographical Source
 It grows in Arabian pennisula, Ethiopia, Nubia, and Somal-
iland.
Myrrh
 Myrrh contains resin (25–40%), gum (57–61%), and
volatile oil (7–17%).
 Large portion of the resin is ether-soluble
containing α-, β-, and γ-commiphoric acids, resenes,
the esters of another resin acid and two phenolic
compounds.
 The volatile oil is a mixture of cuminic aldehyde,
eugenol, cresol, pinene, limonene, dipentene, and two
sesquiterpenes.
 The disagreeable odour of the oil is due to mainly the
disulphide.
 Chemical Tests
 A yellow brown emulsion is produced on trituration
with water.
 Ethereal solution of Myrrh turns red on treatment
with bromine vapours. The solution becomes purple
with nitric acid.
 Myrrh is used as carminative and in incense and
perfumes. It has local stimulant and antiseptic
properties and is utilized in tooth powder and as mouth
wash. Topically it is astringent to mucous membranes.

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Resin.ppt

  • 1. Dr. M. A. Quazi M.Pharm, Ph. D. Resins
  • 2. 1 • Benzoin 2 • Guggul 3 • Ginger 4 • Asafoetida 5 • Colophony 6 • Myrrh Contents
  • 3.  any natural or synthetic organic compound consisting of a noncrystalline or viscous liquid substance.  Natural resins are typically fusible and flammable organic substances that are transparent or translucent and are yellowish to brown in colour.  They are formed in plant secretions and are soluble in various organic liquids but not in water.  Resin formation occurs as a result of injury to the bark from wind, fire, lightning, or other cause. Introduction
  • 4.  Synonyms:  Gum Benjamin; Benzoinum; Benzoin; Luban (Hindi)  Biological Source:  Benzoin is obtained from the incised stem of Styrax benzoin, Styrax paralleloneurus, Styrax tonkinensis, belonging to family Styraceae.  Geographical Source  The trees are found in Sumatra, Malacca, Malaya, Java, and Borneo. Benzoin
  • 5.  Cultivation & Collection  In Sumatra the seeds are sown in rice fields.  The rice plants provide protection to benzoin plants during first year.  After harvesting of the rice crop the trees are allowed to grow.  When they are 7 years old, three triangular wounds are made in a vertical row.  Tapping consists of making in each trunk three lines of incisions which are gradually lengthened.  The first secretion is very sticky and is rejected.  A single tree yields about 10 kg of resin per year and is completely exhausted by the 19th year of its life.
  • 6.  Sumatra benzoin occurs in brittle masses consisting of opaque, whitish, or reddish tears embedded in a translucent, reddish-brown or greyish-brown, resinous matrix.  Odour, agreeable and balsamic,  taste, slightly acrid. 
  • 7.  Chemical Constituents  Sumatra Benzoin consists of free balsamic acid (cinnamic and benzoic acids) (25%) and their esters.
  • 8.  Uses  Sumatra Benzoin possesses expectorant, antiseptic, carminative, stimulant, and diuretic properties. It is used in cosmetic lotions, perfumery
  • 9.  Synonyms:  Gumgugul, Salai-gogil.  Biological Source:  Guggal is a gumresin obtained by incision of the bark of Commiphora mukul belonging to family Burseraceae.  Geographical Source  The tree is a small, thorny plant distributed throughout India.  Each plant yields about one kilogram of the product, which is collected in cold season. Guggul
  • 10.  Guggal occurs as viscid, brown tears; or in fragment pieces, mixed with stem, piece of bark; golden yellow to brown in colour.  With water it forms a milk emulsion.  It has a balsamic odour  taste is bitter, aromatic.
  • 11.  Guggal contains gum (32%), essential oil (1.45%),  sterols (guggulsterols I to VI, β-sitosterol, cholesterol, Z- and E-guggulsterone),  sugars (sucrose, fructose),  amino acids, α-camphorene, cembrene,  flavonoids (quercetin and its glycosides),  ellagic acid, myricyl alcohol, etc.
  • 12.
  • 13.  Guggal significantly lowers serum triglycerides and cholesterol as well as LDL and VLDL cholesterols  is astringent, aritirheumatic, antiseptic, expectorant, aphrodisiac, demulcent, and emmenagogue.
  • 14.  Synonyms:  Rhizoma zingiberis, Zingibere. Adrak  Biological Source:  Ginger consists of the dried rhizomes of the Zingiber officinale belonging to family Zingiberaceae..  Oleo resin  Geographical Source  It is mainly cultivated in West Indies, Nigeria, Jamaica, India, Japan, and Africa. Ginger
  • 15.  Dark Brown  Aromatic, Pungent  Viscous liquid  Cultivation and Collection  Rhizomes (Fingers)  Loamy soil  Well drained soil  Percolation
  • 16.  Ginger contains 1 to 2% volatile oil, 5 to 8% pungent resinous mass and starch.
  • 17.  Uses  Sore throat, hoarseness, and loss of voice are benefited by chewing a piece of ginger.  Ginger is used as an antiemetic, spasmolytic, aromatic stimulant, carminative, condiment, and flavouring agent.
  • 18.  Synonyms:  Devil’s dung; food of the gods; asafoda; asant; hing (Hindi).  Biological Source:  Asafoetida is an oleo-gum resin obtained as an exudation by incision of the decapitated rhizome and roots of Ferula asafoetida , F. foetida, F. rubricaulis , and some other species of Ferula, belonging to family Apiaceae..  Geographical Source  The plant grows in Iran, Turkestan and Afghanistan (Karam and Chagai districts). Asafoetida
  • 19.  Collection  The plant is a perennial branching, 3 m high herb possessing large schizogeneous ducts and lysigenous cavities containing milky liquid. Upon exudation and drying of the liquid, Asafoetida is obtained.  For the collection of the drug the upper part of the root is laid bare and the stem cut off close to the crown in March–April.  Removal of the exudation and exposure of fresh surface proceeds until the root is exhausted.
  • 20.  Asafoetida occurs as a soft solid mass or irregular lumps or ‘tears’, sometimes almost semiliquid.  Tears are rounded or flattened and about 5–30 mm in diameter,  grayish-white or dull yellow or reddish brown in colour.  Asafoetida has a strong garlic-like (alliaceous) odour and a bitter, acrid and alliaceous taste.
  • 21.  Asafoetida contains volatile oil (4–20%), resin (40– 65%), and gum (25%).
  • 22.  Chemical Tests  On trituration with water it produces a milky emulsion.  The drug (0.5 g) is boiled with hydrochloric acid (5 ml) for sometime. It is filtered and ammonia is added to the filtrate. A blue fluorescence is obtained.  To the fractured surface add 50% nitric acid. Green colour is produced.  To the fractured surface of the drug, add sulphuric acid (1 drop). A red colour is obtained which changes to violet on washing with water.  Uses  Asafoetida is used as carminative, expectorant, antispas- modic, and laxative
  • 23.  Synonyms:  Rosin, yellow resin; Abietic anhydride; colophony resin; amber resin; resin; coloponium.  Biological Source:  Colophony is a solid residue left after distilling off the volatile oil from the oleoresin obtained from Pinus palustris (long leaf pine) and other species of Pinus such as P. pinaster, P. halepensis, P. massoniana, P. tabuliformis, P. carribacea ., belonging to family Pinaceae.  Geographical Source  The genus Pinus is widely found in United States, France, Italy, Portugal, Spain, Greece, New Zealand, China, India (Himalayan region) Colophony
  • 24.  Colophony occurs as translucent, hard, shiny, sharp, pale yellow to amber fragments,  fracture brittle at ordinary temperature,  burns with smoky flame,  slight turpentine-like odour and taste,  melts readily on heating, density 1.07–1.09.  It is insoluble in water but freely soluble in alcohol, benzene, ether, glacial acetic acid, oils, carbon disulphide, and alkali solutions.
  • 25.  Colophony contains resin acids (about 90%), resenes, and fatty acid esters. Of the resin acids about 90% are isomeric α-, β-, and γ-abietic acids; the other 10% is a mixture of dihydroabietic
  • 26.  To a solution of powdered resin (0.1 g) in acetic acid (10 ml) one drop of conc. Sulphuric acid is added in a test tube. A purple colour, readily changing to violet, is formed.   2. To a petroleum ether solution of powdered Colophony twice its volume of dilute solution of copper acetate is shaken. The colour of the petroleum ether layer changes to emerald-green due to formation of copper salt of abietic acid.
  • 27.  Colophony is used as stiffening agent in ointments, adhesives, plasters and cerates and as a diuretic in veterinary medicine.  Commercially it is used to manufacture varnishes, printing inks, cements, soap, sealing wax, wood polishes, floor coverings, paper, plastics, fireworks, tree wax, rosin oil, and for water proofing cardboard.
  • 28.  Synonyms:  Gum-resin Myrrh; Gum Myrrh; Arabian or Somali Myrrh; Myrrha.  Biological Source:  Myrrh is an oleo gum-resin obtained from the stem of Commiphora molmol or C. abyssinica or other species of Commiphora, belonging to family Burscraceae.  Geographical Source  It grows in Arabian pennisula, Ethiopia, Nubia, and Somal- iland. Myrrh
  • 29.  Myrrh contains resin (25–40%), gum (57–61%), and volatile oil (7–17%).  Large portion of the resin is ether-soluble containing α-, β-, and γ-commiphoric acids, resenes, the esters of another resin acid and two phenolic compounds.  The volatile oil is a mixture of cuminic aldehyde, eugenol, cresol, pinene, limonene, dipentene, and two sesquiterpenes.  The disagreeable odour of the oil is due to mainly the disulphide.
  • 30.  Chemical Tests  A yellow brown emulsion is produced on trituration with water.  Ethereal solution of Myrrh turns red on treatment with bromine vapours. The solution becomes purple with nitric acid.
  • 31.  Myrrh is used as carminative and in incense and perfumes. It has local stimulant and antiseptic properties and is utilized in tooth powder and as mouth wash. Topically it is astringent to mucous membranes.