We suggest that unless considerable attention is made to strengthening the essential scientific discipline of Bio Statistical Programming Services, the value of our health research investment, in terms of better health and lives saved, is endangered.
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Biostatistics is a critical subject in current health data research – pubrica
1. BIOSTATISTICS IS A
CRITICAL SUBJECT IN
CURRENT HEALTH
DATA RESEARCH
An Academic presentation by
Dr. Nancy Agnes, Head, Technical Operations, Pubrica
Group: www.pubrica.com
Email: sales@pubrica.com
3. Introduction
The National Health and Medical Research Council
(NHMRC) of Australia spends over $800 million per
year on medical and public health research, most of
which is dependent on accurate data analysis and
interpretation.
We suggest that unless considerable attention is
made to strengthening the essential scientific
discipline of Bio Statistical Programming Services, the
value of our health research investment, in terms of
better health and lives saved, is endangered.
4. This danger is exacerbated by the development of research opportunities
provided by the significant data age, which quickly increases the availability
and scale of new data, needing a better grasp of statistical concerns and
computational tools.
Concerns about Australia’s biostatistical underpinnings were expressed in a
statement released by the International Society of Biostatistics.
5.
6. THE PROBLEM
In the presence of unpredictability and uncertainty, statistical reasoning
offers the theoretical foundation for extracting information from data.
Most experimental research in public health and clinical care relies on
biostatistical input on everything from study design to data analysis and
reporting, with the best studies combining biostatistical information on
everything from study design to data analysis and recording.
7. Clinical biostatistics programming service approaches are at the
foundation of essential public health research disciplines, including
epidemiology and health services research, a function that reflects the
discipline’s basic character.
On the other hand, bioinformatics and computational biology are vital
emerging areas in data-intensive biomedical research that are anchored
by statistical principles and methodologies and components highly
informed by other basic disciplines like computer science and
mathematics.
8. “These issues [of poor study design, conduct, and analysis] are often
related to misuse of statistical methods, which is exacerbated by
inadequate training in methods,” according to a recent review of the scale
of waste and ineffectiveness in health research, echoing similar
observations made more than two decades earlier.
Importantly, biostatistics, as a subdiscipline of clinical case report
statistical service (perhaps the first “data science “5), is a recognized
scientific discipline in its own right, rather than a collection of procedures
that must be applied appropriately.
9. Not only does good biostatistical work include an understanding of
mathematics, probability, and causes of bias, which underpin statistical
theory and methodologies, but it also necessitates (and increasingly)
substantial technological capabilities, such as computers.
To develop these abilities and the understanding required to conceptualize
issues and traverse the difficult seas between real-world health challenges
and complicated methodologies, in-depth training is essential.
According to a recent analysis, most physicians struggle to complete such
training. A superficial comprehension of statistics can readily lead to
improper behaviour and be criticized.
10. Recognition of biostatistics as an academic field, essential to the
intellectual architecture of the larger research enterprise, is required for the
development of biostatistics as a core subject within educational health
and medical research.
This necessitates systems that support biostatistical work at all levels, from
nonspecialists like physicians through master’s level biostatistics graduates
and doctorate students, postdoctoral researchers, and research leaders in
biostatistical methods.
Necessary steps
11. ·The requirement for academic effort across this spectrum is common in
other fields of science, but it is sometimes overlooked in biostatistics due to
a propensity to treat the subject as merely a toolset of procedures rather
than a growing scientific discipline.
Medical Biostatistical Programming Service comprises a long process that
includes mathematical derivations and conceptualizations, simulation
studies, thorough case studies, and the translation of newly created
methodologies for use by other researchers.
12. ·The development of marginal structural models, which enabled the
appropriate handling of time-dependent confounding in treatment
decisions based on CD4 cell count levels that are themselves affected by
treatment, was critical in the wave of research into antiretrovirals for the
treatment of human immunodeficiency virus infection.
The training of future biostatistical leaders must also include experience in
methodological research.
13. Other countries have recognized the critical role of biostatistics in health
and medical research. Many major universities in the United States have
biostatistics departments established in the 1970s thanks to financing from
the National Institutes of Health for biostatistical research training
programmes, with a call for a renewed effort to expand biostatistical
training programmes in 2006.
THE INTERNATIONAL
SITUATION AND AUSTRALIA’S
POSITION
14. In a similar vein, the Medical Research Council in the United Kingdom has
long supported a national centre in biostatistical methodology — the
Medical Research Council’s Biostatistics Unit — and many methodology
hubs whose core research agenda is the statistical methodology, which
has been funded since 2009.
Similar to Europe and the United States, Australia has never invested
systematically in developing biostatistics, either in universities or industry.
15. Inappropriately, there is no simple fix for the issues raised, but we feel the
following initiatives are necessary to enhance and promote the biostatistics field
in Australia
Universities and research institutes must foster the development of
organizational structures with a critical mass of academic biostatisticians
working in methodology and collaborating with health researchers, as well as
training opportunities and career development for biostatisticians;
Biostatistics Clinical trial Research Services and advanced training must keep
pace with the dramatic changes in the data science landscape to ensure that
graduates have the necessary breadth of knowledge.
POTENTIAL SOLUTIONS
16. Pubrica’s team of researchers and authors create scientific and medical
research articles that practitioners and authors may use as a valuable
resource. Pubrica medical writers may assist you in writing and editing the
introduction by alerting the reader to any flaws or gaps in the selected
study field.
Our professionals understand the framework that follows the broad topic,
problem, and background and then move on to a more specific topic to
establish the hypothesis.
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