PPT is about atherosclerosis and its development.

2.  Understand the course of events that lead to
atherosclerosis.

3.  Almost 18 million people die
each year from CVD.
 WHO data from 2017

4.  Also known as hardening of the arteries, is
caused primarily by the damage to the delicate
endothelium of an artery followed by an
inflammatory response, plaques(yellowish
fatty substance) build up on the inside of
arteries.

5.  Plaques are most likely to form in the arteries
of neck(carotid art.) and heart(coronary art.).

7.  1. Damage of inner wall (high blood pressure or
chemicals in cigarette)
 2. Inflammatory response begins, WBC arrive
 3. Cholesterol deposited , makes atheroma
 4. Fibrous tissue and calcium ions, harden it
changing into hardened plaque.
 5. Blood vessels become less elastic and
narrower.

9.  Because of the high pressure, artery bulges and
the wall becomes more sensitive to pressure,
known as aneurysm.

10.  This can lead to severe damage in a number
of organs:
 1. Kidneys – by testing protein in urine we
can find it
 2. Eyes – can cause blindness
 3. Brain – can cause stroke

11.  2 common examples are:
 1. Angina – coronary artery partially blocked
 2. Myocardial infarction (Heart attack) -
coronary artery fully blocked

13.  Options for angina treatment include:
 Lifestyle changes
 Medications (Ex.: aspirin)
 Angioplasty and stenting
 Open-heart surgery (coronary bypass surgery)

14.  A clot that gets
stuck in a
coronary artery
is known as a
coronary
thrombosis.

15.  Common heart attack symptoms include:
 Chest pain that may feel like pressure, tightness, pain,
squeezing or aching
 Pain or discomfort that spreads to the shoulder, arm,
back, neck, jaw, teeth or sometimes the upper belly
 Cold sweat
 Fatigue
 Heartburn or indigestion
 Lightheadedness or sudden dizziness
 Nausea
 Shortness of breath