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The GAVI Alliance

Iain Simpson


The Power of Vaccines
London, May 18th 2012
GAVI has supported countries in preventing
more than 5.5 million future deaths




Source: These estimates and projections are produced by the WHO Department of Immunization, Vaccines
and Biologicals, based on the most up-to-date data and models available as of 30 September 2011.
*Polio estimate includes deaths averted by vitamin A supplements supported by GAVI.

                                                             Basic facts about GAVI
                                                                     DATE
A strong platform




Source: WHO/UNICEF, UN population division

                                             Basic facts about GAVI
                                                     DATE
Causes of child deaths in low-income
countries




Source: WHO, World Health Statistics 2011

                                            Basic facts about GAVI
                                                    DATE
Children immunised with pneumococcal and
rotavirus vaccines




Source: WHO-UNICEF coverage estimates for 1980-2010, as of July 2011. Coverage projections
for 2011-2012, as of September 2011. World Population Prospects, the 2010 revision. New York,
United Nations, 2010 (surviving infants).

                                                               Basic facts about GAVI
                                                                       DATE
Increased competition reduces vaccine price
Price decline of pentavalent vaccine and number of manufacturers
from which vaccines were procured in each year




Source: UNICEF Supply Division, 2012   Basic facts about GAVI
                                               DATE
Tiered pricing
2011 prices per dose




Source: UNICEF Supply Division; CDC   Basic facts about GAVI
                                              DATE
Increasing number of GAVI vaccine suppliers
based in emerging markets




Source: UNICEF Supply Division, 2011   Basic facts about GAVI
                                               DATE
Human papillomavirus (HPV)


 The cause of cervical cancer, which kills
  over 270,000 women every year
 85% of deaths are in developing countries
 Vaccines can protect against the HPV types
  causing 70% of cervical cancer cases
 GAVI is working with partners to reduce
  prices and prepare for introduction in GAVI-
  eligible countries



                      Basic facts about GAVI
                              DATE
Malaria


 Caused about 780,000 deaths in 2009,
  mainly among children in Africa
 First vaccine could be recommended for
  use by WHO in 2015
 GAVI continues to monitor the development
  of malaria vaccine
 GAVI will be instrumental in ensuring
  vaccines are available and accessible to the
  developing world


                     Basic facts about GAVI
                             DATE
Over 19 million children still unimmunised
Global number of under-five children unimmunised with 3 doses of DTP




Source: WHO/UNICEF coverage estimates
2010 revision. July 2011

                                        Basic facts about GAVI
                                                DATE
Impact 2011–2015
 GAVI can prevent 3.9 million future deaths between 2011 and 2015




Source: GAVI Alliance Strategic Demand Forecast
version 2.0 and Long Range Cost and Impact Model
                                                   Basic facts about GAVI
                                                           DATE
Thank you




                                     GAVI/10/Ricci Shryock




            Basic facts about GAVI
                    DATE
Basic facts about GAVI
        DATE

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The GAVI Alliance

  • 1. The GAVI Alliance Iain Simpson The Power of Vaccines London, May 18th 2012
  • 2. GAVI has supported countries in preventing more than 5.5 million future deaths Source: These estimates and projections are produced by the WHO Department of Immunization, Vaccines and Biologicals, based on the most up-to-date data and models available as of 30 September 2011. *Polio estimate includes deaths averted by vitamin A supplements supported by GAVI. Basic facts about GAVI DATE
  • 3. A strong platform Source: WHO/UNICEF, UN population division Basic facts about GAVI DATE
  • 4. Causes of child deaths in low-income countries Source: WHO, World Health Statistics 2011 Basic facts about GAVI DATE
  • 5. Children immunised with pneumococcal and rotavirus vaccines Source: WHO-UNICEF coverage estimates for 1980-2010, as of July 2011. Coverage projections for 2011-2012, as of September 2011. World Population Prospects, the 2010 revision. New York, United Nations, 2010 (surviving infants). Basic facts about GAVI DATE
  • 6. Increased competition reduces vaccine price Price decline of pentavalent vaccine and number of manufacturers from which vaccines were procured in each year Source: UNICEF Supply Division, 2012 Basic facts about GAVI DATE
  • 7. Tiered pricing 2011 prices per dose Source: UNICEF Supply Division; CDC Basic facts about GAVI DATE
  • 8. Increasing number of GAVI vaccine suppliers based in emerging markets Source: UNICEF Supply Division, 2011 Basic facts about GAVI DATE
  • 9. Human papillomavirus (HPV)  The cause of cervical cancer, which kills over 270,000 women every year  85% of deaths are in developing countries  Vaccines can protect against the HPV types causing 70% of cervical cancer cases  GAVI is working with partners to reduce prices and prepare for introduction in GAVI- eligible countries Basic facts about GAVI DATE
  • 10. Malaria  Caused about 780,000 deaths in 2009, mainly among children in Africa  First vaccine could be recommended for use by WHO in 2015  GAVI continues to monitor the development of malaria vaccine  GAVI will be instrumental in ensuring vaccines are available and accessible to the developing world Basic facts about GAVI DATE
  • 11. Over 19 million children still unimmunised Global number of under-five children unimmunised with 3 doses of DTP Source: WHO/UNICEF coverage estimates 2010 revision. July 2011 Basic facts about GAVI DATE
  • 12. Impact 2011–2015 GAVI can prevent 3.9 million future deaths between 2011 and 2015 Source: GAVI Alliance Strategic Demand Forecast version 2.0 and Long Range Cost and Impact Model Basic facts about GAVI DATE
  • 13. Thank you GAVI/10/Ricci Shryock Basic facts about GAVI DATE
  • 14. Basic facts about GAVI DATE