3. Definition
• The process in which glucose is broken down
to produce energy.
• It produces two molecules of pyruvate, ATP,
NADH and water.
• The process takes place in the cytosol of the
cell
4. Steps
• Two phases :
A. Energy investment phase
Preparatory phase (first 5 steps).
B. Energy yielding phase
Energy payoff phase (second 5 steps)
5. Transfers a phosphoryl group from ATP onto the
glucose to form G6P.
>Requires ATP
converts G6P to F6P
6. phosphorylates F6P on C1, yielding FBP.
Requires ATP
cleaves the 6-carbon FBP into 2 different
3-carbon molecules.
9. Steps 6–10: 2nd Half of Glycolysis
catalyzes the phosphorylation and oxidation of
GA yielding 1,3-biphosphoglycerate (1,3-BPG).
converts 1,3-BPG to 3-phosphoglycerate (3PG).
Produces ATP.
10. onverts 3PG to 2-phosphoglycerate (2PG) .
by transferring the functional group
phosphate from C3 to C2.
2PG to phosphoenolpyruvate (PEP).
11. converts PEP to pyruvate (Pyr),
releasing a large amount of
energy, which is used to
drive the synthesis of ATP.
> Produces ATP
