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Answers to Questions from Asymmetric Synthesis 2020
STUDY MATERIAL FOR UG IVTH SEMSESTER: PAPER-C10T Page 1
Answers to Questions from Asymmetric Synthesis
DR. SATYAJIT DEY
Department of Chemistry : Tamralipta Mahavidyalaya
______________________________________________________________
Q. No. 1: Predict the major product(s) in each of the following reactions, paying attention
to stereochemistry.
Answer:
A)
B)
C)
D)
Answers to Questions from Asymmetric Synthesis 2020
STUDY MATERIAL FOR UG IVTH SEMSESTER: PAPER-C10T Page 2
E)
You will get similar stereo-chemical result when methyl group is replaced by phenyl
group.
Q. No. 2: Which would be the appropriate starting material for the synthesis of the given
target molecule with the stereochemistry shown? Explain with retro-synthetic analysis
and mechanism.
Answer:
______________________________________________________________
_____
Answers to Questions from Asymmetric Synthesis 2020
STUDY MATERIAL FOR UG IVTH SEMSESTER: PAPER-C10T Page 3
Q. No. 3: For each of the following molecules, do you expect to form as the major product the (Z)‐
or (E)‐enolate on reaction with lithium diisopropylamine in THF?
Answer:
A) B) C)
______________________________________________________________

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Answers to questions from asymmetric synthesis

  • 1. Answers to Questions from Asymmetric Synthesis 2020 STUDY MATERIAL FOR UG IVTH SEMSESTER: PAPER-C10T Page 1 Answers to Questions from Asymmetric Synthesis DR. SATYAJIT DEY Department of Chemistry : Tamralipta Mahavidyalaya ______________________________________________________________ Q. No. 1: Predict the major product(s) in each of the following reactions, paying attention to stereochemistry. Answer: A) B) C) D)
  • 2. Answers to Questions from Asymmetric Synthesis 2020 STUDY MATERIAL FOR UG IVTH SEMSESTER: PAPER-C10T Page 2 E) You will get similar stereo-chemical result when methyl group is replaced by phenyl group. Q. No. 2: Which would be the appropriate starting material for the synthesis of the given target molecule with the stereochemistry shown? Explain with retro-synthetic analysis and mechanism. Answer: ______________________________________________________________ _____
  • 3. Answers to Questions from Asymmetric Synthesis 2020 STUDY MATERIAL FOR UG IVTH SEMSESTER: PAPER-C10T Page 3 Q. No. 3: For each of the following molecules, do you expect to form as the major product the (Z)‐ or (E)‐enolate on reaction with lithium diisopropylamine in THF? Answer: A) B) C) ______________________________________________________________