2. Neonates
•
Major adjustments in physiology
•
First signs of congenital problems
•
At risk of serious bacterial infection
•
No baseline for normal state
•
Inexperience of parent –infant
interaction
3. Signs and symptoms
•
Less specific
– Changes to feeding, vomiting
– Behaviour, tone
– Urine and stool output
– Colour, perfusion
– Breathing, apnoea
5. Catherine
•
10 days old, born at term, normal
delivery, first child, breast fed, had
regained birth weight
•
2 days ‘off colour’, shorter feeds
•
24 hours vomiting small amounts at end
of feed
•
Fever to 38.3oC overnight
10. James
•
9 days old, born at term, normal
delivery, second child, breast fed, had
regained birth weight
•
2 days ‘off colour’, shorter feeds
•
24 hours vomiting small amounts at end
of feed
•
No fever
11. Examination
•
Airway patent
•
No respiratory distress, chest clear
•
Pink, bradycardic 80, perfusion reduced
•
Quiet, reduced response, normal tone
•
Apnoea noted responding to stimulation
•
Sepsis treatment started
12. Electrolytes
•
Na 123, K 10.33
•
Glucose 2.8
•
Lactate 3.4
•
ECG –runs of ventricular tachycardia
•
Lab results –Creatinine 133
17. Sam
•
7 days old, born at term, normal
delivery, second child, bottle fed, still
below birth weight
•
Fussy feeder, breaks off during feed
•
24 hours vomiting small amounts at end
of feed
•
No fever
18. Examination
•
Airway patent
•
Grunting, tachypnoeic, chest clear
•
Pale, tachycardic 188, perfusion
reduced, skin mottled and grey legs
•
Poorly responsive to mother, floppy
•
Apnoea noted responding to stimulation
•
Bedside blood sugar 4.6
19. Cardiac examination
•
Femoral pulses impalpable
•
BP normal in both arms and unable to
record in legs
•
No murmurs heard
•
Diagnosis of Coarctation of the aorta
•
Shock following closure of ductus
arteriosus
20. Treatment
•
Treat for sepsis
•
Fluid to support preload
•
Prostaglandin infusion to open duct
•
Intubation to avoid apnoea
•
Consider fentanyl for sedation
21. Jasmine
•
9 days old, born at term, normal
delivery, second child, bottle fed, still
below birth weight
•
Difficulty feeding
•
48 hours green vomits after each feed
•
No fever