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Third Quarter Fiscal 2012
Earnings Conference Call
                 Sept. 6, 2012




                 www.nordion.com
Caution on Forward Looking Statements



This presentation contains forward-looking statements, within the meaning of applicable securities laws, including under
applicable Canadian securities laws and the “safe harbor” provisions of the United States Private Securities Litigation Reform Act
of 1995. These statements can be identified by expressions of belief, expectation or intention, as well as those statements that are
not historical fact. The words “may”, “will”, “could”, “should”, “would”, “outlook”, “believe”, “plan”, “anticipate”, “estimate”, “project”,
“expect”, “intend”, “indicate”, “forecast”, “objective”, “optimistic”, and similar words and expressions are also intended to identify
forward-looking statements. Forward-looking statements are necessarily based on estimates and assumptions made by us in light
of our experience and our perception of historical trends, current conditions and expected future developments, as well as other
factors that we believe are appropriate in the circumstances, but which are inherently subject to significant business, political,
economic and competitive uncertainties and contingencies. Known and unknown factors could cause actual results to differ
materially from those projected in the forward-looking statements. Accordingly, this presentation is subject to the disclaimer and
qualified by the assumptions, qualifications and risk factors referred to in our 2011 Annual Information Form (AIF). Factors that
could cause actual results or events to differ materially from current expectations include, but are not limited to, fluctuations in
supply and demand, pricing pressures and rising costs, changes in currency and exchange rates and potential adverse
developments in new and pending legal proceedings or regulatory investigations, as well as the risk factors which are described
in section 5 of our 2011 AIF and in our other filings with the Canadian provincial securities commissions and the US Securities
and Exchange Commission, and our success in anticipating and managing those risks. We caution readers not to place undue
reliance on the Company’s forward-looking statements, as a number of factors could cause our actual results, performance or
achievements to differ materially from the beliefs, plans, objectives, expectations, anticipations, estimates and intentions
expressed in such forward-looking statements. The Company does not assume any obligation to update or revise any forward-
looking statements, whether written or oral, that may be made from time to time by us or on our behalf, except as required by
applicable law.




                                                                                                                                               2
Non GAAP Information



To supplement the financial measures prepared in accordance with generally accepted accounting principles (GAAP), the
company uses non-GAAP financial measures such as adjusted net income and adjusted earnings per share. Non-GAAP financial
measures exclude certain items, such as restructuring charges and recovery, change in fair value of embedded derivatives, AECL
arbitration and legal fees, loss and gains on sales of investments, loss or gains on discontinued operations, and tax effects on
adjusted items. Management uses non-GAAP financial measures internally for strategic decision making, forecasting future
results and evaluating current performance. By disclosing non-GAAP financial measures, management intends to provide
investors with a meaningful, consistent comparison of the company's core operating results and trends for the periods presented.
Non-GAAP financial measures are not prepared in accordance with GAAP. Therefore, the information is not necessarily
comparable to other companies and should be considered as a supplement to, not a substitute for, or superior to, the
corresponding measures calculated in accordance with GAAP.




                                                                                                                                   3
Third Quarter Fiscal 2012
Earnings Conference Call
                      Steve West
            Chief Executive Officer
                     Sept. 6, 2012




                      www.nordion.com
Q3 2012 Results
        Targeted Therapies        Sterilization Technologies        Medical Isotopes


     Segmented Revenue                                         Segmented Earnings*
     (US$ millions)                                            (US$ millions)
80                                                        25

70
                                                          20
60

50           32.1                    32.1                                                            14.4
                                                          15           15.3
40

                                                          10
30
             21.4                    19.7
20                                                                                                   5.3
                                                           5            4.8
10
             13.3                    15.3
                                                                                                     3.6
                                                                        2.1
 0                                                         0
            2011                    2012                               2011                          2012
                             Q3                                                        Q3
                                                               * Excludes corporate segmented loss          5
Arbitration Timeline
   February 2006-                             May 16, 2008 -
   Nordion exchanged all of its ownership     AECL and the Government of
   rights and obligations in the MAPLE        Canada announced their intention
   Facilities for a new 40 year long term     to discontinue the MAPLE project     October 21, 2011 -           September 10, 2012 -
   supply of isotopes to be produced in the   without prior notice to or           Ongoing arbitration with     Nordion to announce
   now AECL-owned MAPLE Facilities.           consultation with MDS                AECL schedule extended.      arbitration panel decision




1998-                                                   July 2008 -                                 May 25, 2012 -
MDS entered into an agreement with AECL                 Nordion served AECL with a notice of        Final arguments completed.
for the design, development and                         arbitration proceedings seeking an
construction of two new nuclear reactors                order to compel AECL to fulfill its
and processing facility, known as the                   contractual obligations.
MAPLE project.




                                                                                                                                             6
Internal Investigation


• Discovered through the Company’s own internal review as part of
  Nordion’s compliance program

• Voluntarily disclosed this issue to regulatory and enforcement
  authorities

• Ceased payments to and terminated our contractual arrangements
  with the affected foreign supplier




                                                                    7
Targeted Therapies: TheraSphere®


• 13% year-over-year                                                            • Growth of ~15%
  revenue growth                                                                  compared to F2011




                                                                 2012 OUTLOOK
                            Q3 RESULTS
• Drove new account                                                             • Continue to drive
  growth in key                                                                   market education,
  markets                                                                         training, sales
• TheraSphere                                                                     growth
  demonstrated                                                                  • Continue to assess
  promising results in                                                            and expand IO
  investigator initiated                                                          portfolio
  independent trials




                                         STRATEGY

                             Establish a leadership position in the
                           emerging interventional oncology (IO) market
                                                                                                      8
Sterilization Technologies


• $32.1 million in                                                                           • Segment revenue
  revenues                                                                                     expected to be ~10%




                                                                              2012 OUTLOOK
                                                                                               lower than F2011
                            Q3 RESULTS
• Supply agreements
  representing two-thirds                                                                    • Co-60 revenue is
  of our 2012 Co-60                                                                            expected to be
  volumes                                                                                      significantly higher in
• Signed multi-year                                                                            the second half of 2012
  supply agreement in                                                                          compared with the first
  June with Japan                                                                              half
  Radioisotope
  Association




                                                    STRATEGY

                                         Maintain the value and selectively
                                           invest in growth opportunities
                                                                                                                  9
Medical Isotopes



• $19.7 million in                                                                           • Solidify long-term




                                                                              2012 OUTLOOK
  revenues                                                                                     supply
• NRU one-month             Q3 RESULTS                                                       • Opportunistically
  planned shutdown as                                                                          grow our customer
  well as unplanned                                                                            base for Medical
  supply interruptions in                                                                      Isotopes as potential
  Q2 and Q3 impacted                                                                           new customers
  revenues                                                                                     continue to diversify
• Nordion is an                                                                                their supply
  important player in the
  medical isotopes
  supply chain – vital to
  physicians and
  patients around the
  world
                                                   STRATEGY


                                         Optimize the value of the business
                                                                                                                    10
Third Quarter Fiscal 2012
Earnings Conference Call
                       Peter Dans
            Chief Financial Officer
                     Sept. 6, 2012




                     www.nordion.com
Q3 2012 Financial Performance

                                                        Segmented Revenue
                                                           (US$ millions)
CONSOLIDATED RESULTS                               80
                                                   70
                                                   60
• Revenue of $67.1 million                         50        32.1          32.1
                                                   40
• GAAP net income of $12.3 million                 30
                                                             21.4          19.7
                                                   20
• Adjusted net income of $15.5 million             10                      15.3
                                                             13.3
                                                    0
                                                            2011           2012
                                                                     Q3


                                                        Segmented Earnings*
SEGMENT RESULTS                                            (US$ millions)
                                                   25
• 13% revenue growth in TheraSphere                20
                                                                           14.4
• Co-60 shipments in Q3 higher than first          15        15.3

  half of fiscal 2012                              10
                                                                            5.3
                                                    5
• NRU shutdowns impacting volumes for                        4.8
                                                                            3.6
                                                    0        2.1
  Mo-99                                                     2011           2012
                                                                     Q3
                                            Targeted           Sterilization
                                                                                  Medical Isotopes
                                            Therapies          Technologies
                                            * Excludes corporate segmented loss            12
Strong Balance Sheet



       SOLID CASH AND LIQUIDITY POSITION
    REFLECTED IN NOTABLE FINANCIAL ASSETS:



    Cash & cash                AECL note               Deferred
    equivalents                receivable              tax asset




  $81.9 $2.3 $76.7
                  $US millions (as of July 31, 2012)               13
Outlook

2012 FINANCIAL OUTLOOK
HIGHLIGHTS
• TheraSphere, Cobalt-60 and Moly 99 are
  expected to:
    – Contribute about 80% of our revenues
    – Greater than 90% of our segment gross
      margins




                                              14
Third Quarter Fiscal 2012
Earnings Conference Call
                 Sept. 6, 2012




                 www.nordion.com

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Nordion Third Quarter Fiscal 2012 Earnings Conference Call

  • 1. Third Quarter Fiscal 2012 Earnings Conference Call Sept. 6, 2012 www.nordion.com
  • 2. Caution on Forward Looking Statements This presentation contains forward-looking statements, within the meaning of applicable securities laws, including under applicable Canadian securities laws and the “safe harbor” provisions of the United States Private Securities Litigation Reform Act of 1995. These statements can be identified by expressions of belief, expectation or intention, as well as those statements that are not historical fact. The words “may”, “will”, “could”, “should”, “would”, “outlook”, “believe”, “plan”, “anticipate”, “estimate”, “project”, “expect”, “intend”, “indicate”, “forecast”, “objective”, “optimistic”, and similar words and expressions are also intended to identify forward-looking statements. Forward-looking statements are necessarily based on estimates and assumptions made by us in light of our experience and our perception of historical trends, current conditions and expected future developments, as well as other factors that we believe are appropriate in the circumstances, but which are inherently subject to significant business, political, economic and competitive uncertainties and contingencies. Known and unknown factors could cause actual results to differ materially from those projected in the forward-looking statements. Accordingly, this presentation is subject to the disclaimer and qualified by the assumptions, qualifications and risk factors referred to in our 2011 Annual Information Form (AIF). Factors that could cause actual results or events to differ materially from current expectations include, but are not limited to, fluctuations in supply and demand, pricing pressures and rising costs, changes in currency and exchange rates and potential adverse developments in new and pending legal proceedings or regulatory investigations, as well as the risk factors which are described in section 5 of our 2011 AIF and in our other filings with the Canadian provincial securities commissions and the US Securities and Exchange Commission, and our success in anticipating and managing those risks. We caution readers not to place undue reliance on the Company’s forward-looking statements, as a number of factors could cause our actual results, performance or achievements to differ materially from the beliefs, plans, objectives, expectations, anticipations, estimates and intentions expressed in such forward-looking statements. The Company does not assume any obligation to update or revise any forward- looking statements, whether written or oral, that may be made from time to time by us or on our behalf, except as required by applicable law. 2
  • 3. Non GAAP Information To supplement the financial measures prepared in accordance with generally accepted accounting principles (GAAP), the company uses non-GAAP financial measures such as adjusted net income and adjusted earnings per share. Non-GAAP financial measures exclude certain items, such as restructuring charges and recovery, change in fair value of embedded derivatives, AECL arbitration and legal fees, loss and gains on sales of investments, loss or gains on discontinued operations, and tax effects on adjusted items. Management uses non-GAAP financial measures internally for strategic decision making, forecasting future results and evaluating current performance. By disclosing non-GAAP financial measures, management intends to provide investors with a meaningful, consistent comparison of the company's core operating results and trends for the periods presented. Non-GAAP financial measures are not prepared in accordance with GAAP. Therefore, the information is not necessarily comparable to other companies and should be considered as a supplement to, not a substitute for, or superior to, the corresponding measures calculated in accordance with GAAP. 3
  • 4. Third Quarter Fiscal 2012 Earnings Conference Call Steve West Chief Executive Officer Sept. 6, 2012 www.nordion.com
  • 5. Q3 2012 Results Targeted Therapies Sterilization Technologies Medical Isotopes Segmented Revenue Segmented Earnings* (US$ millions) (US$ millions) 80 25 70 20 60 50 32.1 32.1 14.4 15 15.3 40 10 30 21.4 19.7 20 5.3 5 4.8 10 13.3 15.3 3.6 2.1 0 0 2011 2012 2011 2012 Q3 Q3 * Excludes corporate segmented loss 5
  • 6. Arbitration Timeline February 2006- May 16, 2008 - Nordion exchanged all of its ownership AECL and the Government of rights and obligations in the MAPLE Canada announced their intention Facilities for a new 40 year long term to discontinue the MAPLE project October 21, 2011 - September 10, 2012 - supply of isotopes to be produced in the without prior notice to or Ongoing arbitration with Nordion to announce now AECL-owned MAPLE Facilities. consultation with MDS AECL schedule extended. arbitration panel decision 1998- July 2008 - May 25, 2012 - MDS entered into an agreement with AECL Nordion served AECL with a notice of Final arguments completed. for the design, development and arbitration proceedings seeking an construction of two new nuclear reactors order to compel AECL to fulfill its and processing facility, known as the contractual obligations. MAPLE project. 6
  • 7. Internal Investigation • Discovered through the Company’s own internal review as part of Nordion’s compliance program • Voluntarily disclosed this issue to regulatory and enforcement authorities • Ceased payments to and terminated our contractual arrangements with the affected foreign supplier 7
  • 8. Targeted Therapies: TheraSphere® • 13% year-over-year • Growth of ~15% revenue growth compared to F2011 2012 OUTLOOK Q3 RESULTS • Drove new account • Continue to drive growth in key market education, markets training, sales • TheraSphere growth demonstrated • Continue to assess promising results in and expand IO investigator initiated portfolio independent trials STRATEGY Establish a leadership position in the emerging interventional oncology (IO) market 8
  • 9. Sterilization Technologies • $32.1 million in • Segment revenue revenues expected to be ~10% 2012 OUTLOOK lower than F2011 Q3 RESULTS • Supply agreements representing two-thirds • Co-60 revenue is of our 2012 Co-60 expected to be volumes significantly higher in • Signed multi-year the second half of 2012 supply agreement in compared with the first June with Japan half Radioisotope Association STRATEGY Maintain the value and selectively invest in growth opportunities 9
  • 10. Medical Isotopes • $19.7 million in • Solidify long-term 2012 OUTLOOK revenues supply • NRU one-month Q3 RESULTS • Opportunistically planned shutdown as grow our customer well as unplanned base for Medical supply interruptions in Isotopes as potential Q2 and Q3 impacted new customers revenues continue to diversify • Nordion is an their supply important player in the medical isotopes supply chain – vital to physicians and patients around the world STRATEGY Optimize the value of the business 10
  • 11. Third Quarter Fiscal 2012 Earnings Conference Call Peter Dans Chief Financial Officer Sept. 6, 2012 www.nordion.com
  • 12. Q3 2012 Financial Performance Segmented Revenue (US$ millions) CONSOLIDATED RESULTS 80 70 60 • Revenue of $67.1 million 50 32.1 32.1 40 • GAAP net income of $12.3 million 30 21.4 19.7 20 • Adjusted net income of $15.5 million 10 15.3 13.3 0 2011 2012 Q3 Segmented Earnings* SEGMENT RESULTS (US$ millions) 25 • 13% revenue growth in TheraSphere 20 14.4 • Co-60 shipments in Q3 higher than first 15 15.3 half of fiscal 2012 10 5.3 5 • NRU shutdowns impacting volumes for 4.8 3.6 0 2.1 Mo-99 2011 2012 Q3 Targeted Sterilization Medical Isotopes Therapies Technologies * Excludes corporate segmented loss 12
  • 13. Strong Balance Sheet SOLID CASH AND LIQUIDITY POSITION REFLECTED IN NOTABLE FINANCIAL ASSETS: Cash & cash AECL note Deferred equivalents receivable tax asset $81.9 $2.3 $76.7 $US millions (as of July 31, 2012) 13
  • 14. Outlook 2012 FINANCIAL OUTLOOK HIGHLIGHTS • TheraSphere, Cobalt-60 and Moly 99 are expected to: – Contribute about 80% of our revenues – Greater than 90% of our segment gross margins 14
  • 15. Third Quarter Fiscal 2012 Earnings Conference Call Sept. 6, 2012 www.nordion.com