The Rule of 72 provides an easy way to estimate how long it will take an investment to double in value based on the annual interest rate. The rule states that the interest rate multiplied by the number of years invested should equal 72. To calculate the time to double, divide 72 by the annual interest rate. To calculate the rate needed to double in a given time, divide 72 by that number of years. The rule is an approximation that becomes less accurate at higher interest rates.