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MEDULLA SPINALIS
Muh.Iqbal Basri
Department of Anatomy
Hasanuddin University
1
The Spinal Cord
Position
 Lies in vertebral canal
 Continuous above with medulla
oblongata at level of foramen
magnum
 Ends below at lower border of
L1 in adult; at birth at level of
L3
 Ascensus medulla
2
External features
 A long cylindrical structure and
slightly flattened anteroposteriorly,
 Conus medullaris
 Filum terminale
 Cauda equina
 Two enlargements (intumescentia)
Cervical enlargement :
corresponds to the C4 to the T1
segments
Lumbosacral enlargement :
corresponds to the L2 to the S3
segments
3
4
5
Fissure and sulci
 Anterior median fissure
 Posterior median sulcus
 Anterolateral sulcus - anterior (motor) roots emerge serially
 Posterolateral sulcus - posterior (sensory) roots enter spinal cord,
each bear a spinal ganglion which constitutes the first cell-station of
the sensory nerves
6
7
8
9
10
11
12
13
Relationship of segments
of spinal cord to vertebrae
 A portion of the cord that gives
rise to a pair of spinal nerve
constitutes a segment.
 There are 31 segments
8 cervical
12 thoracic
5 lumbar
5 sacral
1 coccygeal
14
Relationship of segments of spinal cord to vertebrae
Spinal segments Vertebral levels (spines)
Upper cervical region (C1~C4) = C1 ~ C4
Lower cervical and upper thoracic
region (C5~T4)
— 1 = C4 ~ T3
Middle thoracic region (T5~T8) — 2 = T3 ~ T6
Lower thoracic region (T9~T12) — 3 = T6 ~ T9
Lumber segments = T10 ~ T12
Sacral and coccygeal segments = L1
15
Internal structures
 Central canal
 Gray matter
 Anterior horn (column)
 Posterior horn (column)
 Intermediate zone
 Lateral horn (column)
 Anterior gray commissures
 Posterior gray commissures
 White matter
 Anterior funiculus
 lateral funiculus
 Posterior funiculus
 Anterior white commisure
16
Posterior horn (column):
 Marginal layer
 Substantia gelatinosa
 Nucleus proprius
 Nucleus thoraccus
in segments C8~L3
17
Intermediate zone
 Intermediolateral nucleus
(lateral horn or column): lies in
segments T1~L3, containing
sympathetic preganglionic
neurons
 Sacral parasympathetic
nucleus: lies in segments S2~S4,
containing parasympathetic
preganglionic neurons
 Intermediomedial nucleus : for
sensation of viscera
18
Anterior horn (column): contain motor
neurons
 Three kinds of neuron
 α-motor neuron: larger multipolar
neuron, innervates extrafusal fibers of
skeletal m., producing contraction of m.
 γ-motor neuron: smaller neuron,
innervates intrafusal fibers regulating
muscular tonus
 Renshaw’s cell: negative feedback
mechanism
 Two groups of nuclei
 Medial nuclear group: present in most
segments of spinal cord, innervating axial
muscles
 Lateral nuclear group: present only in
cervical and lumbosacral enlargements,
innervating limb muscles
19
Rexed’s lamina
 posterior horn is formed
by lamina toⅠ Ⅵ ;
 Intermediate zone
corresponding to
lamina Ⅶ ;
 Anterior horn is
composed laminae Ⅷ
and Ⅸ ;
 lamina is the grayⅩ
matter surrounding the
central canal.
20
Important Subdivision of Spinal Cord Gray Matter
Region Lamina Nucleus
Posterior horn Ⅰ Marginal layer
Ⅱ Substantia gelatinosa
Ⅲ, Ⅳ Nucleus proprius
Intermediate zone Ⅶ Nucleus thoracicus (C8~L3)
Ⅶ Intermediolateral nucleus (T1~L3)
Ⅶ Sacral parasympathetic nucleus (S2~S4)
Ⅶ Intermediomedial nucleus
Anterior horn Ⅸ Motor neuron
21
White matter
White matter contains three kinds of fibers:
ascending, descending, and fasciculus proprius
22
Ascending tracts
Fasciculus cuneatus
Fasciculus gracilis
Posterior spinocerebellar tract
Anterior spinocerebellar tract
Spinothalamic tract
23
24
25
Ascending tracts
Tract Site of origin Funiculus Termination Function
Fasciculus
gracilis
Spinal ganglia
below segment
T5
Posterior Gracile
nucleus
Convey
proprioceptive
and fine touch
sensation of
trunk and limbsFasciculus
cuneatus
Spinal ganglia
above segment
T4
Cuneate
nucleus
Posterior
spinocerebellar
Homolateral
nucleus
thoracicus
Lateral Cerebellum Unconscious
proprioception
from lower limb
and lower
portion of trunkAnterior
spinocerebellar
Contralateral
Laminae
Ⅴ~Ⅶ
Spinothalamic Laminae ,Ⅰ
Ⅳ~Ⅶ
Lateral
and
anterior
Dorsal
thalamus
Pain,
temperature and
simple touch
sensation of
trunk and limbs
26
Descending tracts
Lateral corticospinal tract
Anterior corticospinal tract
Rubrospinal tract
Vestibulospinal tract
Reticulospinal tract
Medial longitudinal fasciculusTectospinal tract
Fasciculus proprius
27
28
Descending tracts
Tract Site of origin Funiculus Termination Function
Lateral
corticospinal
Cerebral cortex Lateral Laminae
Ⅳ~Ⅸ
anterior
horn
Voluntary movement
Anterior
corticospinal
Cerebral cortex Anterior
Rubrospinal Red nucleus Lateral Laminae
Ⅶ~Ⅶ
Excitatory of flexors
Vestibulospinal Homolateral
vestibular
nuclei
Anterior Laminae
Ⅶ~Ⅷ
Excitatory of extensors
Reticulospinal Reticular
formation
Anterior
and lateral
Laminae
Ⅶ~Ⅷ
Voluntary movement
Medial
longitudinal
fasciculus
Vestibular
nuclei
Anterior Laminae
Ⅶ~Ⅷ
Coordinate neck with eye
movement
Tectospinal Superior
colliculus
Anterior Laminae
Ⅵ~Ⅷ
Fasciculus
proprius
Spinal cord Anterior,
lateral and
posterior
Spinal cord Intrinsic reflex
mechanism of spinal cord
29
30
Main functions of spinal cord
 Conduction of excitations
 Reflex activity
31
32
TABLE : TRACTUS ASCENDENS, DESCENDENS and
ASCENDENS+DESCENDENS
FUNICULUS ASCENDENS DESCENDENS ASCENDENS+DE
SCENDENS
ANTERIOR
1. Tractus
Spinothalamicus
Anterior
1. Tractus
Corticospinalis
Anterior
2. Tractus
Vestibulospinalis
3. Tractus
Reticulospinalis
4. Tractus
Tectospinalis
1. Fasciculus
Proprius Anterior
2. Fasciculus
Septomarginalis
Anterior
33
TABLE : TRACTUS ASCENDENS, DESCENDENS and
ASCENDENS+DESCENDENS
FUNICULUS ASCENDENS DESCENDENS ASCENDENS+DE
SCENDENS
LATERALIS
1. Tractus
Spinocerebellari
s Ventralis
2. Tractus
Spinocerebellari
s Dorsalis
3. Tractus
Spinothalamicus
Lateralis
4. Tractus
Spinotectalis
1. Tractus
Corticospinalis
Lateralis
2. Tractus
Olivospinalis
1. Fasciculus
Propius Lateralis
34
TABLE : TRACTUS ASCENDENS, DESCENDENS dan
ASCENDENS+DESCENDENS
FUNICULUS ASCENDENS DESCENDENS ASCENDENS+DE
SCENDENS
POSTERIOR
1. Fasciculus
Gracilis
2. Fasciculus
Cuneatus
1. Fasciculus
Propius
Posterior
2. Fasciculus
Interfascicularis
Propius (a,b,c,d)
35
Keterangan :
A = Coma Schultze
B = Tractus Septomarginalis (T bawah)
C = Area Ovalis Flechsig (L)
D = Trigonum Philipe Gombault (S)
36
 TRACTUS/FASCICULUS
1. Tractus Spinothalamicus Anterior (touch + press)
2. Tractus Spinothalamicus Lateralis (pain + thermal)
3. Tractus Spinocerebellaris Ant/Ventral (muscle
tones+ tendo)
4. Tractus Spinocerebellaris Post/Dorsal (muscle
tones+ tendo)
5. Tractus Corticospinalis Ant/Lat (motoric)
6. Fasciculus Cuneatus
7. Fasciculus Gracilis
37
(position, movement,
discrimination,vibration)
38
39

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Medulla spinalis (2)

  • 1. MEDULLA SPINALIS Muh.Iqbal Basri Department of Anatomy Hasanuddin University 1
  • 2. The Spinal Cord Position  Lies in vertebral canal  Continuous above with medulla oblongata at level of foramen magnum  Ends below at lower border of L1 in adult; at birth at level of L3  Ascensus medulla 2
  • 3. External features  A long cylindrical structure and slightly flattened anteroposteriorly,  Conus medullaris  Filum terminale  Cauda equina  Two enlargements (intumescentia) Cervical enlargement : corresponds to the C4 to the T1 segments Lumbosacral enlargement : corresponds to the L2 to the S3 segments 3
  • 4. 4
  • 5. 5
  • 6. Fissure and sulci  Anterior median fissure  Posterior median sulcus  Anterolateral sulcus - anterior (motor) roots emerge serially  Posterolateral sulcus - posterior (sensory) roots enter spinal cord, each bear a spinal ganglion which constitutes the first cell-station of the sensory nerves 6
  • 7. 7
  • 8. 8
  • 9. 9
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  • 13. 13
  • 14. Relationship of segments of spinal cord to vertebrae  A portion of the cord that gives rise to a pair of spinal nerve constitutes a segment.  There are 31 segments 8 cervical 12 thoracic 5 lumbar 5 sacral 1 coccygeal 14
  • 15. Relationship of segments of spinal cord to vertebrae Spinal segments Vertebral levels (spines) Upper cervical region (C1~C4) = C1 ~ C4 Lower cervical and upper thoracic region (C5~T4) — 1 = C4 ~ T3 Middle thoracic region (T5~T8) — 2 = T3 ~ T6 Lower thoracic region (T9~T12) — 3 = T6 ~ T9 Lumber segments = T10 ~ T12 Sacral and coccygeal segments = L1 15
  • 16. Internal structures  Central canal  Gray matter  Anterior horn (column)  Posterior horn (column)  Intermediate zone  Lateral horn (column)  Anterior gray commissures  Posterior gray commissures  White matter  Anterior funiculus  lateral funiculus  Posterior funiculus  Anterior white commisure 16
  • 17. Posterior horn (column):  Marginal layer  Substantia gelatinosa  Nucleus proprius  Nucleus thoraccus in segments C8~L3 17
  • 18. Intermediate zone  Intermediolateral nucleus (lateral horn or column): lies in segments T1~L3, containing sympathetic preganglionic neurons  Sacral parasympathetic nucleus: lies in segments S2~S4, containing parasympathetic preganglionic neurons  Intermediomedial nucleus : for sensation of viscera 18
  • 19. Anterior horn (column): contain motor neurons  Three kinds of neuron  α-motor neuron: larger multipolar neuron, innervates extrafusal fibers of skeletal m., producing contraction of m.  γ-motor neuron: smaller neuron, innervates intrafusal fibers regulating muscular tonus  Renshaw’s cell: negative feedback mechanism  Two groups of nuclei  Medial nuclear group: present in most segments of spinal cord, innervating axial muscles  Lateral nuclear group: present only in cervical and lumbosacral enlargements, innervating limb muscles 19
  • 20. Rexed’s lamina  posterior horn is formed by lamina toⅠ Ⅵ ;  Intermediate zone corresponding to lamina Ⅶ ;  Anterior horn is composed laminae Ⅷ and Ⅸ ;  lamina is the grayⅩ matter surrounding the central canal. 20
  • 21. Important Subdivision of Spinal Cord Gray Matter Region Lamina Nucleus Posterior horn Ⅰ Marginal layer Ⅱ Substantia gelatinosa Ⅲ, Ⅳ Nucleus proprius Intermediate zone Ⅶ Nucleus thoracicus (C8~L3) Ⅶ Intermediolateral nucleus (T1~L3) Ⅶ Sacral parasympathetic nucleus (S2~S4) Ⅶ Intermediomedial nucleus Anterior horn Ⅸ Motor neuron 21
  • 22. White matter White matter contains three kinds of fibers: ascending, descending, and fasciculus proprius 22
  • 23. Ascending tracts Fasciculus cuneatus Fasciculus gracilis Posterior spinocerebellar tract Anterior spinocerebellar tract Spinothalamic tract 23
  • 24. 24
  • 25. 25
  • 26. Ascending tracts Tract Site of origin Funiculus Termination Function Fasciculus gracilis Spinal ganglia below segment T5 Posterior Gracile nucleus Convey proprioceptive and fine touch sensation of trunk and limbsFasciculus cuneatus Spinal ganglia above segment T4 Cuneate nucleus Posterior spinocerebellar Homolateral nucleus thoracicus Lateral Cerebellum Unconscious proprioception from lower limb and lower portion of trunkAnterior spinocerebellar Contralateral Laminae Ⅴ~Ⅶ Spinothalamic Laminae ,Ⅰ Ⅳ~Ⅶ Lateral and anterior Dorsal thalamus Pain, temperature and simple touch sensation of trunk and limbs 26
  • 27. Descending tracts Lateral corticospinal tract Anterior corticospinal tract Rubrospinal tract Vestibulospinal tract Reticulospinal tract Medial longitudinal fasciculusTectospinal tract Fasciculus proprius 27
  • 28. 28
  • 29. Descending tracts Tract Site of origin Funiculus Termination Function Lateral corticospinal Cerebral cortex Lateral Laminae Ⅳ~Ⅸ anterior horn Voluntary movement Anterior corticospinal Cerebral cortex Anterior Rubrospinal Red nucleus Lateral Laminae Ⅶ~Ⅶ Excitatory of flexors Vestibulospinal Homolateral vestibular nuclei Anterior Laminae Ⅶ~Ⅷ Excitatory of extensors Reticulospinal Reticular formation Anterior and lateral Laminae Ⅶ~Ⅷ Voluntary movement Medial longitudinal fasciculus Vestibular nuclei Anterior Laminae Ⅶ~Ⅷ Coordinate neck with eye movement Tectospinal Superior colliculus Anterior Laminae Ⅵ~Ⅷ Fasciculus proprius Spinal cord Anterior, lateral and posterior Spinal cord Intrinsic reflex mechanism of spinal cord 29
  • 30. 30
  • 31. Main functions of spinal cord  Conduction of excitations  Reflex activity 31
  • 32. 32
  • 33. TABLE : TRACTUS ASCENDENS, DESCENDENS and ASCENDENS+DESCENDENS FUNICULUS ASCENDENS DESCENDENS ASCENDENS+DE SCENDENS ANTERIOR 1. Tractus Spinothalamicus Anterior 1. Tractus Corticospinalis Anterior 2. Tractus Vestibulospinalis 3. Tractus Reticulospinalis 4. Tractus Tectospinalis 1. Fasciculus Proprius Anterior 2. Fasciculus Septomarginalis Anterior 33
  • 34. TABLE : TRACTUS ASCENDENS, DESCENDENS and ASCENDENS+DESCENDENS FUNICULUS ASCENDENS DESCENDENS ASCENDENS+DE SCENDENS LATERALIS 1. Tractus Spinocerebellari s Ventralis 2. Tractus Spinocerebellari s Dorsalis 3. Tractus Spinothalamicus Lateralis 4. Tractus Spinotectalis 1. Tractus Corticospinalis Lateralis 2. Tractus Olivospinalis 1. Fasciculus Propius Lateralis 34
  • 35. TABLE : TRACTUS ASCENDENS, DESCENDENS dan ASCENDENS+DESCENDENS FUNICULUS ASCENDENS DESCENDENS ASCENDENS+DE SCENDENS POSTERIOR 1. Fasciculus Gracilis 2. Fasciculus Cuneatus 1. Fasciculus Propius Posterior 2. Fasciculus Interfascicularis Propius (a,b,c,d) 35 Keterangan : A = Coma Schultze B = Tractus Septomarginalis (T bawah) C = Area Ovalis Flechsig (L) D = Trigonum Philipe Gombault (S)
  • 36. 36
  • 37.  TRACTUS/FASCICULUS 1. Tractus Spinothalamicus Anterior (touch + press) 2. Tractus Spinothalamicus Lateralis (pain + thermal) 3. Tractus Spinocerebellaris Ant/Ventral (muscle tones+ tendo) 4. Tractus Spinocerebellaris Post/Dorsal (muscle tones+ tendo) 5. Tractus Corticospinalis Ant/Lat (motoric) 6. Fasciculus Cuneatus 7. Fasciculus Gracilis 37 (position, movement, discrimination,vibration)
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  • 39. 39