Ns11 Limbic System

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NS11
Lecture 11 of 63 in the Neuroscience Module

"Limbic System" [Anatomy]

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Ns11 Limbic System

  1. 1. Limbic System Dr. Skantha Kandiah MBA, MSc (NUI), MB BCh BAO (NUI), LRCP & SI Senior Lecturer in Anatomy and Lecturer in Healthcare Management RCSI
  2. 2. Limbic System <ul><li>Cingulate gyrus </li></ul><ul><li>Hippocampus </li></ul><ul><li>Fornix </li></ul><ul><li>Mamillary bodies </li></ul><ul><li>Septal nuclei </li></ul><ul><li>Amygdala </li></ul>
  3. 7. FORNIX <ul><li>CONNECTS MAMMILLARY BODIES TO HIPPOCAMPUS </li></ul><ul><li>Efferent fibres from hippocampus form fimbria </li></ul>
  4. 9. <ul><li>NUCLEUS ACCUMBENS </li></ul><ul><ul><li>Stimulation – sense of well-being </li></ul></ul><ul><ul><li>Connection to basal nuclei – </li></ul></ul><ul><ul><ul><li>motor expression of emotion? </li></ul></ul></ul><ul><ul><li>SEPTAL AREA – stimulation – sensation like orgasm </li></ul></ul><ul><ul><ul><li>Destruction of septal area -- rage </li></ul></ul></ul>
  5. 10. AMYGDALA <ul><li>At tip of tail of caudate nucleus and anterior horn of lateral ventricle </li></ul><ul><li>Fear – important for survival </li></ul><ul><li>? Overactivity – rage </li></ul><ul><li>? Role in phobias </li></ul><ul><li>Bilateral ablation – timidity, hypersexuality. </li></ul>
  6. 12. HIPPOCAMPUS <ul><li>IMPORTANT FOR MEMORY </li></ul><ul><li>3 layers of cells (allocortex) </li></ul><ul><li>Alzheimer’s disease </li></ul><ul><ul><li>General cortical degeneration </li></ul></ul><ul><ul><li>Hippocampal degeneration (bilateral) – cannot form new memories </li></ul></ul><ul><ul><li>Frontal degeneration – inappropriate behaviour, later -= attention and motivation deficit </li></ul></ul>

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