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GOOD
MORNI
NG
PREPAREDBY:
MS. MARUTHU. G,
M.Sc., (N),
DEPARTMENT OF PSYCHIATRY
14 December 2017MHC, TVPM
4
Alcohol &
drugs are a
Major Public
Health
Problem
ABUSE:
IT REFERS TO MALADAPTIVE
PATTERN OF SUBSTANCE USE THAT
IMPAIRS HEALTH IN A BROAD SENSE.
DEPENDENCE:
IT REFERS TO CERTAIN
PHYSILOGICAL AND
PSYCHOLOGICAL PHENOMENA
INDUCED BY THE REPEATED TAKING
OF SUBSTANCE.
TOLERANCE:
IT IS A STATE IN WHICH AFTER
REPEATED ADMINISTRATION, A DRUG
PRODUCES A DECREASED EFFECT,
ON INCREASING DOSES ARE
REQUIRED TO PRODUCE THE SAME
EFFECT.
INTOXICATION:
A PHYSICAL AND MENTAL
STATE OF EXHILARATION AND
EMOTIONAL FRENZY OR LETHARGY
AND STUPOR.
WITHDRAWAL STATE:
A GROUP OF SIGNS AND SYMPTOMS
RECURRING WHEN A ADDICTIVE
SUBSTANCES IS REDUCED IN AMOUNT
OR WITHDRAWN, WHICH LAST FOR A
LIMITED TIME. THE NATURE OF THE
WITHDRAWAL STATE IS RELATED TO THE
CLASS OF SUBSTANCE USED.
CO-DEPENDENCY:
CO-DEPENDENCY REFERS TO AN
UNCONSCIOUS ADDICTION TO ANOTHER
PERSON’S ABNORMAL BEHAVIOUR
- WEKESSER, 1994
SUBSTANCE – RELATED DISORDER :
“A substance – related disorder is a
condition ( such as intoxication, harmful
use / abuse , dependence, withdrawal, and
psychoses or amnesia associated with the
use of substance ) associated with
substance abuse, often involving
maladaptive behaviours over a long
period of time”.
- Wikipedia
CLASSIFICATION:
-- SUBSTANCE USE DISORDERS
(SUD)
-- SUBSTANCE - INDUCED
DISORDERS (SID)
-
It include
- substance abuse
- substance dependence
 “Substance abuse is a maladaptive
pattern of substance use manifested by
recurrent and significant adverse
consequences related to repeated use of
the substance”
 Substance dependence refers to
certain physiological and psychological
phenomena induced by the repeated
taking of a substance.
 Substance induced disorders
include medical conditions that can be
directly attributed to the use of a
substance.
Intoxication
Withdrawal
Delirium
Dementia
Amnesia
Psychosis
Mood disorders
Anxiety disorders
Sexual dysfunction
Sleep disorders
Alcohol
Amphetamines
and related
substances
Caffeine
Cannabis
Cocaine
Hallucinogens
Inhalants
Nicotine
Opioids
Phencyclidine
(PLP) and related
substances
Sedatives,
hypnotics, or
anxiolytics.
20
ALCOHOL DEPENDENCE
Alcoholism refers to the
use of alcoholic beverages to
the point of causing damage to
the individual, society or both.
14 December
2017
MHC, TVPM
22
 BIOLOGICAL FACTORS
 BEHAVIOURAL THEORIES
 PSYCHOLOGICAL & INTERPERSONAL
FACTORS
 SOCIAL FACTORS
 EASY AVAILABILITY
 PSYCHIATRIC DISORDER
I. EXPERIMENTAL
II. RECREATIONAL
III. RELAXATIONAL
IV. COMPULSIVE
I. PRE – ALCOHOLIC PHASE
II. THE EARLY ALCOHOLIC OR
PRODROMAL PHASE
III. THE CRUCIAL PHASE
IV. THE CHRONIC PHASE
ACUTE INTOXICATION
WITHDRAWAL SYNDROME
14 December 2017MHC, TVPM
32
Complications
14 December
2017
MHC, TVPM
33
Family
 Marital disharmony, separations,
divorces, spouse abuse, child
abuse
 In wife- anxiety and depression
 In children- aggression, anxiety,
poor school performance.
Social
 unable to marry, Social isolation,
loss of hobbies, interests and
creativity
14 December
2017
MHC, TVPM
34
Sexual dysfunction
 Infertility
 Impotence,  sexual desire
Work
Intoxication during work,
absences, sick leave, 
illnesses, arguments, aggression,
crime, sleeping at work, quarrels,
unreliability.
14 December
2017
MHC, TVPM
35
Financial
 Debts, taking advances
Legal
 Murder, assaults, drunken driving,
shop lifting, sexual offences.
Accidents
 At home, office, work place, fire,
drowning, road traffic accidents.
14 December 2017
MHC, TVPM
36
Medical Management for
alcoholism
14 December 2017MHC, TVPM
37
C A G E - for alcohol dependence
Cut down alcohol ?
Annoyed when discussed ?
Guilt about drinking ?
Eye opening drinking ?
14 December 2017MHC, TVPM
38
DIAGNOSIS:
Examination of the patient
History
Physical examination
Time last dose was taken
Lab tests for LFT, Blood picture,
Blood sugar
Examination for withdrawal
symptoms.
TREATMENT
DETOXIFICATION ALCOHOL
DEPENDANCE
 AIM : SYMPTOMATIC MANAGEMENT
 DRUG OF CHOICE : BENZODIAZEPINES
CHLORDIAZEPOXIDE
DIAZEPAM
VITAMIN SUPPLEMENT
(THIAMINE 100 mg)
 CARE OF DEHYDRATION
 ALCOHOL DETERRENT THERAPY
DISULFIRAM
 BEHAVIOUR THERAPY
14 December 2017
MHC, TVPM
43
VENTLATION
INTERPRETATIONRE-EDUCATION
 GROUP THERAPY
ALCOHOLIC
ANONYMOUS -
 AVERSION THERAPY :
IT INVOLVES THE USE OF A DAILY DOSE
OF DISULFRUM TO PREVENT COMPULSIVE
DRINKING
 MECHANISM OF ACTION
 DOSE – 250 – 500 mg/day
 DURATION
 CONTRAINDICATION
 TAKE CONSENT
 ATLEAST 12 hrs
ELAPSED
 INSTRUCTIONS
 Pt. SHOULD BE
WARNED AGAINST
INGESTION
 ADVICES
 AVOID CNS
DEPRESSANTS
 AVOID DRIVING
 PATIENT SHOULD BR WARNED ABOUT
DISULFIRAM ALCOHOL REACTION
 CARRY IDENTIFICATION CARD
 FOLLOW – UP
 ANTI – CARVING AGENTS
 OTHER MEDICATIONS
 THREE MAJOR COMPONENTS OF
REHABILITATION :
a) Continued efforts to increase &
maintain high levels of motivation for
abstinence
b) Work to help patient readjust to a
lifestyle free of alcohol
c) Relapse prevention
14 December
2017
MHC, TVPM
52
 Awareness among
professionals
 Early identification
 History taking- tactful,
confidential, in privacy,
without degrading patient
Distribution:
* Alcohol – 42%
* Opium – 20%
* Heroin – 13%
* Cannabis – 6.2%
* Others – 1.8%
the majority of drug addicts are aged
between 16 and 30 years.
 Prevalence low.
 Majority of Heavy Drug users
 Health and social problems are high
14 December 2017MHC, TVPM
57
 Heroin – Brown sugar, smack
 Morphine
 Pethidine
 Buprenorphine
 Fortwin – [Pentazocine]
 Dextropropoxyphene
 Codeine
Apathy
Bradycardia
Hypotension
Respiratory depression
Subnormal temperature
Pinpoint pupils
Delayed reflexes
Thready pulse and coma can occur
 Watery eyes
 Running nose
 Yawning
 Loss of appetite
 Irritability
 Tremors
 Sweating
 Nausea
 Diarrhoea
 Insomnia
 Raised body
temperature
 Piloerection
 Anorexia
Parkinsonism
Peripheral neuropathy
Transverse myelitis
Skin infection – IV use
Thrombophlebitis
Pulmonary embolism
Endocarditis
Septicemia
AIDS, viral hepatitiis, tetanus
Involvement in criminal activities
Overdose – narcotic antagonists ex-
naloxone, naltrexone
Detoxification – methadone, clonidine,
naltrexone, buprenorphine.
Maintenance – methadone, opioid
antagonists, psychological methods like
individual psychotherapy, behaviour
therapy, group therapy, family therapy
Derived from HEMP PLANT, CANNABIS
SATIVA
The dried leaves and flowering tops are
often referred as Ganja or Marijuna
The resin in the plant is referred as hashish
Bhang is a drink made from cannabis
Cannabis is either smoked or taken in
liquid form
Mild impairment of
consciousness and
orientation
Tachycardia
A sense of floating in
the air
Euphoria
Dream like states
Flashback
phenomena
Alteration in
psychomotor
activity
Tremors
Photophobia
Lacrimation
Dry mouth
Increased
appetite
Mostly found in the first 72-96 hours
Include :
* Incresed salivation
* Hyperthermia
* Insomnia
* Decreased appetite
* Loss of weight
Transient or short lasting psychiatric
disorders such as
# Acute anxiety
# Paranoid psychosis
# Hysteria
# Hypomania
# Schizophrenia
Amotivational syndrome
Memory impairment
Supportive and
symptomatic treatment
Common street name is ‘crack’
It can be administered orally, intranasally
by smoking, or parenterally.
Pupillary dialatation
Tachycardia
Hypertension
Sweating
Nausea
Hypo manic picture
Agitation
Depression
Anorexia
Fatigue
sleepiness
Acute anxiety reaction
Uncontrolled compulsive
behaviour
Seizures
Respiratory depression
Cardiac arrhythmias
Management of intoxication: amyl
nitrite is an antidote; diazepam or
propranolol is also used
Withdrawal symptoms:
antidepressants and psychotherapy.
Amphetamines are powerful CNS
stimulants with peripheral
sympathomimetic effects.
Commonly used Amphetamines are
pemoline and methylphenidate
Insomnia
Restlessness
Irritability
Paranoid
hallucinatory
syndrome
Amphetamine
induced
psychosis
Tachycardia
Hypertension
Cardiac failure
Seizures
Tremors
Hyperpyrexia
Pupillary dilatation
Panic
Depression
Apathy
Fatigue
Hypersomnia or
insomnia
Agitation
hyperphagia
Seisures
Delirium
Arrhythmias
Aggressive
behaviour
coma
LSD is a powerful
hallucinogen and was first
synthesized in 1938
It presumably produces is
effects by acting on 5-HT
levels in brain.
A common pattern of LSD
use is ‘trip’
Perceptual changes
occurring in clear
consciousness, for example,
Depersonalization
Derealisation
Illusions
Synaesthesia's
Autonomic hyperactivity
Marked anxiety
Paranoid ideation
Impairment of judgment
Flashbacks
Complications
Anxiety
Depression
Psychosis
Visual hallucinosis
Symptomatic treatment
Antianxiety
Antidepressants
Antipsychotic medications
Commonly abused
barbiturates are
* Secobarbital
* Pentobarbital
* Amobarbital
Irritability
Lability of mood
Disinhibited behaviour
Slurring of speech
Incoordination
Attention and memory
impairment
Skin abscesses
Cellulitis
Infection
Embolism
Hypersensivity reactions
Restlessness
Tremors
Seizures
Delirium tremens
Induce vomiting
Use of activated charcoal which reduce
absorption
Symptomatic treatment
Thank You

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