Biology is Technology
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Martine's personal experience and projections as to the interchangeability of biology and technology. These experiences span translating natural navigational skills into technological capabilities via satellite systems, and expressing natural communication via the electronic voices of satellite radio. Failures of biology and shown to be fixable with technology performing biological functions. Consciousness itself, purportedly a uniquely human trait is also shown to be technologically replicable.3
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Biology is Technology
- 1. Biology is Technology Martine Rothblatt mar@unither.com New York City, 23 June 2016 Martine Rothblatt of unither.com 1
- 2. Biology & Technology • BIOLOGY: Something that increases negative entropy by streaming order onto itself • TECHNOLOGY: Something that increases negative entropy pursuant to intent • INTENT: Simulation, Selection & Satisfaction of alternative realities • ERGO: Biology, used with intent, is Technology • ERGO: Self-Replicative Technology, is Biology Martine Rothblatt of unither.com 2
- 3. Schrödinger Model Environment -Intent (No Sim) + Intent (Sim) +/- Intent (+/- Sim) Negative Entropy Biology Technology Humanity Martine Rothblatt of unither.com 3
- 4. My Technologies Were Extensions of My Biology Martine Rothblatt of unither.com 4
- 5. My Negative Entropy Simulated, Selected & Satisfied Other Realities Martine Rothblatt of unither.com 5
- 6. The Technology Self-Replicated With Biology Martine Rothblatt of unither.com 6
- 7. Failure of Biology Fixed With Biology As Technology 7Martine Rothblatt of unither.com
- 8. Intention is Darwinian Variation & Selection At Hyper-Speed Martine Rothblatt of unither.com 8
- 9. End-Stage Organ Failure Cries Out for Technological Biology Martine Rothblatt of unither.com 9
- 10. Practical Step 1: Save the 80% of BDD Lungs That Are Trashed Today Martine Rothblatt of unither.com 10
- 11. 103 104 105 2015 2020 2025 2030 EVLP XENO REGEN SELF-GEN IPS cell re-differentiation 3d scaffold printing 106 Martine Rothblatt of unither.com 11
- 12. 12Martine Rothblatt of unither.com
- 13. Intention Is Not Limited to Today’s Brains Martine Rothblatt of unither.com 13
- 14. Martine Rothblatt of unither.com 14 Consciousness is to Brains as Flight Is to Birds: Similar Functions Arise From Diverse Forms
- 15. Souls Emerge From Minds & Mindfiles, As Technology Emerges From Biology Martine Rothblatt of unither.com 15
- 16. THAT WHICH IS EMERGENT RESHAPES THAT FROM WHICH IT EMERGED, i.e., PROGENY INTEGRATES PEDIGREE Synthetic Biology = most salient tool at hand, for making, changing, savingMartine Rothblatt of unither.com 16
- 17. SYNTH BIOLOGY IS AS OLD AS: > HOW MAN MADE DOGS; > HOW WOMAN MADE GRAINS; AND AS NEW AS > HOW BIOTECH MADE MEDS; > HOW WE’LL MAKE ORGANS. BIO-XP 3200Martine Rothblatt of unither.com 17
- 18. IF DNA REARRANGING DIDN’T EXIST, WE WOULDN’T EXIST & IF WE DON’T ACCELERATE DNA EDITING, MANY OF US 10 BILLION MAY NOT Martine Rothblatt of unither.com 18
- 19. BIOLOGY CAN SEEM WEIRDTECH, BUT WEIRD IS NOT UNETHICAL • UTILITY MUST EXCEED YUCKINESS, • WHICH IS EASY WHEN BIOLOGY AS TECHNOLOGY IS: > LIFE-SAVING > OR SIMPLY MORE CONVENIENT THAN DISGUSTING Martine Rothblatt of unither.com 19
- 20. SUMMARY • INTENTIONAL USE OF BIOLOGY BECOMES TECHNOLOGY • I’VE USED IT TO SPREAD SATELLITE RADIO & HELP THOUSANDS MANAGE THEIR DISEASES • I’M USING IT TO CREATE AN UNLIMITED SUPPLY OF TRANSPLANTABLE ORGANS • IT WOULD BE STUPID TO ABJURE NATURE’S GREATEST INVENTION SINCE CHEMISTRY Martine Rothblatt of unither.com 20
Editor's Notes
- Our first product is called Remodulin, approved for subcutaneous delivery. This product revolutionized the delivery of prostacyclin therapy, making continuous infusion for the first time consistent with an active lifestyle – something very important in a disease that strikes young women and men.
- I cannot begin to tell you the trials and tribulations. I found a molecule that just worked in de-oxygenated arteries, but it was locked up in a freezer at a giant pharmaceutical company. The company refused to develop it because the disease was too rare for them to make money off of. When I finally bought it out of the company, there was no way to create more than a a couple of grams of it at a time, because it was such an unstable molecule. When I finally found a chemist who could make enough of it to use in clinical trials, there was no way to give it to patients because it only lasted a half-hour, so the patients would need it pumped into their body 24/7 for every day of their life. When I found a way to do that unobtrusively, and consistent with a pretty normal life, the clinical trial missed a statistical requirement for FDA approval by 1% point. It was love, baby, love of our daughter, that carried us through all of these trials and tribulations.
- I questioned authority that the problem was not enough organ donors, because 40% of Americans carried organ donor cards but barely one person in a hundred who needed a lung transplant could get on the waiting list. Have 2x or 3x as many organ donors would not solve the problem oftransplantable lungs.
- As a first step, I decided to try to save the thousands of lungs that are donated and not even used. Indeed, I learned that 4 out of 5 lungs donated were being thrown away because they looked too bad by the time a transplant surgeon looked at them. So, we funded the invention of a new technology called Ex Vivo Lung Perfusion, or EVLP. This technology is a machine that works like an artificial body to give a donated but unuseable lung a chance to be restored so that it is good for transplantation. Here is a video of how it works. VIDEO PLAY. Over 400 lives have now been saved with this technology. The people with these artificially restored lungs have the same outcomes as people whose organs come directly from a donor.
- A three times larger facility, if limited to PAH, would be needed to solve all lung transplant needs of people of people with PAH who are excluded from the transplant list. The Ewing Cole design shown here would accommodate 3000 lung pairs per year, and cover about 30 acres including waste treatment areas. Such a facility would most likely be used to triple America’s ability to provide transplants for many end-stage lung diseases – from Pulmonary Hypertension to Pulmonary Fibrosis, and from Cystic Fibrosis to Emphysema.
- If you would like more color on any of these topics, especially about the purpose of biotechnology being to step-by-step defeat death, then I encourage you to either download or buy my book Virtually Human, or to stream or DVD my movie The Singularity Is Near with Ray Kurzweil, Pauley Perrette of Navy NCIS, and Tony Robbins. Thanks so much, and have a great day!