Foodborne illnesses are caused by improper food handling, preparation, or storage and can be caused by contamination from pesticides, medicines, or toxic substances. Each year in the United States, an estimated 48 million people experience foodborne illnesses, which cause around 3,000 deaths annually. Foodborne illnesses may lead to health issues like dehydration or long-term complications. Challenges to food safety include changes in food production and supply, environmental changes leading to contamination, emerging pathogens and antibiotic resistance, and rising numbers of multistate outbreaks. There are three main categories of food contamination hazards: chemical, biological, and mechanical.