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ANATOMY OF
ESOPHAGUS
AND
PHYSIOLOGY
OF
SWALLOWING
ANATOMY OF ESOPHAGUS
– C6 TO T11
– Total length of 25 cm
– Esophagus is the narrowest region of Digestive tract
– Has 3 constrictions
– 15 cm from the incissors
– 23 cm
– 40 cm
Esophageal wall
– 4 layers
– Mucosa
– Submucosa
– Muscularis propria
– Upper 1/3 striated
– Lower 1/3 smooth
– Adventitia
Nerve supply of Esophagus
– Straited muscle is supplied by recurrent laryngeal nerve.
– Smooth muscle is supplied by parasympathetic fibres from the vagus.
– They form two plexus
– Myenteric plexus and Messners plexus.
– Sympathetic supply comes from Cardiac plexus.
Afferent fibres for temperature sentivity is carried along these same fibres.
Blood supply
– Cervical esophagus- inferior Thyroid artery and left subclavian artery.
– Thoracic part has segmental supply from descending aorta and branches of
bronchial and intercostal arteries.
– Abdominal part is supplied by left gastric artery and left phrenic artery.
– Venous drainage is to both systemic as well as portal venous system.
– Lymphatic supply:
Cervical Part drains to lower deep cervical and paratracheal
Thoracic part drains into Posterior mediastinal and Tracheobronchial
group of lymph nodes
Abdominal part drains into left gastric nodes
Relationships of Esophagus
Physiology of Swallowing
– Eating and swallowing are complex behaviors that include volitional and
reflexive activities involving more than 30 nerves and muscles
– The basic musculature of swallowing controls the jaw, the tongue, the degree of
constriction and length of the pharynx and closure of the laryngeal inlet
THE SEQUENCE OF EVENTS IN
THE NORMAL SWALLOW
– 1. Oral
– 2. Pharyngeal
– 3. Oesophageal
ORAL PHASE
– Food is readied for swallowing by reducing and mixing it with saliva by the
muscles of the jaw and oral cavity.
– Again divided into two
– Preparatory phase
– Oral phase proper
Oral Preparatory Phase of the
Swallow
– The food is manipulated (masticated if a solid) into a cohesive unit (referred to as a
bolus) in preparation for the remaining phases of the swallow
– Food is chewed and mixed with saliva to form a bolus
– Bolus is positioned on the tongue for transport
– “Chipmunk Swallow or Pocketing”, when a large bolus is partially held in the cheeks
and the patient then swallows several times to clear the oral cavity-food left in the
cheek is a sign of weak musculature
Oral phase proper
– The food is moved back through the mouth with a front-to-back squeezing
action
– Performed primarily by the tongue
PHARYNGEAL PHASE
– As the bolus is moved back by the tongue to enter the pharynx, a sequence of
events is initiated that ensures that the airways are protected during bolus
transport
– Firstly, diaphragmatic contraction is inhibited making simultaneous breathing
and swallowing impossible under normal circumstances. At the same time, the
soft palate is elevated to ensure a sphincteric closure of the nasopharynx.
– Finally, the vocal cords start to close to protect the airways.
ESOPHAGEAL PHASE:
– The cricopharyngeus relaxes
– The bolus passes through the sphincter and moves along the oesophagus by
peristalsis
Neural control
– Neural control of the complex activity of healthy swallowing involves a number of
different regions of the central nervous system (CNS).
– Consists mainly 4 components
1. The efferent nervous system (motor nerve fibres- Cranial nerve and Ansa cervicalis)
2. The afferent nervous system (Sensory nerve fibres- Cranial Nerve)
3. The Midbrain and cerebral synaptic nerve fibres that connects to swallowing centres
4. The paired swallowing centres in brainstem
Afferent
Nerve
Fibres
Brainstem
swallowing
centre
Cerebral
cortex
centre
Efferent
nerve fibres
– The major sensory stimuli needed to elicit swallowing are thought to originate
from the fauces, pharynx, and posterior larynx
Brain stem swallow Centers
– The swallow centers are not discrete focal areas, but consist of ill-defined broad
zones.
– Located lateral to the midline and ventral to the caudal portion of the fourth
ventricle, which incorporate the nucleus tractus solitarius (NTS) and the
ventromedial reticular formation (VMRF).
RESPIRATION AND SWALLOWING
– Respiration and swallowing are inextricably linked as they use the same
structures and thus the two processes must be finely coordinated
– Swallowing tends to occur during the expiration phase of respiration. Expiration
occurs after 80–100 percent of healthy swallows. This is likely to be a protective
mechanism: material left in the laryngeal vestibule post swallow will be moved
to the pharynx rather than sucked into the lungs.
–
TESTING OF ESOPHAGUS
Radiological Evaluation
Pathological findings
Killian–Jamieson diverticula
and pouches
– NOT TO BE CONFUSED WITH KILLIANS DEHISENCE
– The Killian –Jamieson space is a triangular area of weakness in the upper
anterolateral cervical esophagus.
– The Killian –Jamieson space is bounded superiorly by the inferior border of the
cricopharyngeus, anteriorly by the cricoid cartilage, and inferomedially by the
suspensory ligament of the esophagus.
– Transient – pouches
– Permanent- Diverticula
Cervical Esophageal Web
• Predominantly from the anterior wall
• 3 –8% of patients who undergo upper gastrointestinal
barium studies and in 16% of patients at autopsy
A web appears on barium studies as a radiolucent bar in the
barium pool.
50% - Dysphagia
Jet phenomenon

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Anatomy of esophagus and physiology of swallowing

  • 2. ANATOMY OF ESOPHAGUS – C6 TO T11 – Total length of 25 cm – Esophagus is the narrowest region of Digestive tract – Has 3 constrictions – 15 cm from the incissors – 23 cm – 40 cm
  • 3. Esophageal wall – 4 layers – Mucosa – Submucosa – Muscularis propria – Upper 1/3 striated – Lower 1/3 smooth – Adventitia
  • 4. Nerve supply of Esophagus – Straited muscle is supplied by recurrent laryngeal nerve. – Smooth muscle is supplied by parasympathetic fibres from the vagus. – They form two plexus – Myenteric plexus and Messners plexus. – Sympathetic supply comes from Cardiac plexus. Afferent fibres for temperature sentivity is carried along these same fibres.
  • 5. Blood supply – Cervical esophagus- inferior Thyroid artery and left subclavian artery. – Thoracic part has segmental supply from descending aorta and branches of bronchial and intercostal arteries. – Abdominal part is supplied by left gastric artery and left phrenic artery. – Venous drainage is to both systemic as well as portal venous system.
  • 6. – Lymphatic supply: Cervical Part drains to lower deep cervical and paratracheal Thoracic part drains into Posterior mediastinal and Tracheobronchial group of lymph nodes Abdominal part drains into left gastric nodes
  • 8. Physiology of Swallowing – Eating and swallowing are complex behaviors that include volitional and reflexive activities involving more than 30 nerves and muscles – The basic musculature of swallowing controls the jaw, the tongue, the degree of constriction and length of the pharynx and closure of the laryngeal inlet
  • 9. THE SEQUENCE OF EVENTS IN THE NORMAL SWALLOW – 1. Oral – 2. Pharyngeal – 3. Oesophageal
  • 10. ORAL PHASE – Food is readied for swallowing by reducing and mixing it with saliva by the muscles of the jaw and oral cavity. – Again divided into two – Preparatory phase – Oral phase proper
  • 11. Oral Preparatory Phase of the Swallow – The food is manipulated (masticated if a solid) into a cohesive unit (referred to as a bolus) in preparation for the remaining phases of the swallow – Food is chewed and mixed with saliva to form a bolus – Bolus is positioned on the tongue for transport – “Chipmunk Swallow or Pocketing”, when a large bolus is partially held in the cheeks and the patient then swallows several times to clear the oral cavity-food left in the cheek is a sign of weak musculature
  • 12.
  • 13. Oral phase proper – The food is moved back through the mouth with a front-to-back squeezing action – Performed primarily by the tongue
  • 14.
  • 15. PHARYNGEAL PHASE – As the bolus is moved back by the tongue to enter the pharynx, a sequence of events is initiated that ensures that the airways are protected during bolus transport – Firstly, diaphragmatic contraction is inhibited making simultaneous breathing and swallowing impossible under normal circumstances. At the same time, the soft palate is elevated to ensure a sphincteric closure of the nasopharynx. – Finally, the vocal cords start to close to protect the airways.
  • 16.
  • 17. ESOPHAGEAL PHASE: – The cricopharyngeus relaxes – The bolus passes through the sphincter and moves along the oesophagus by peristalsis
  • 18. Neural control – Neural control of the complex activity of healthy swallowing involves a number of different regions of the central nervous system (CNS). – Consists mainly 4 components 1. The efferent nervous system (motor nerve fibres- Cranial nerve and Ansa cervicalis) 2. The afferent nervous system (Sensory nerve fibres- Cranial Nerve) 3. The Midbrain and cerebral synaptic nerve fibres that connects to swallowing centres 4. The paired swallowing centres in brainstem
  • 20.
  • 21. – The major sensory stimuli needed to elicit swallowing are thought to originate from the fauces, pharynx, and posterior larynx
  • 22. Brain stem swallow Centers – The swallow centers are not discrete focal areas, but consist of ill-defined broad zones. – Located lateral to the midline and ventral to the caudal portion of the fourth ventricle, which incorporate the nucleus tractus solitarius (NTS) and the ventromedial reticular formation (VMRF).
  • 23. RESPIRATION AND SWALLOWING – Respiration and swallowing are inextricably linked as they use the same structures and thus the two processes must be finely coordinated – Swallowing tends to occur during the expiration phase of respiration. Expiration occurs after 80–100 percent of healthy swallows. This is likely to be a protective mechanism: material left in the laryngeal vestibule post swallow will be moved to the pharynx rather than sucked into the lungs. –
  • 27.
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  • 30.
  • 31. Killian–Jamieson diverticula and pouches – NOT TO BE CONFUSED WITH KILLIANS DEHISENCE – The Killian –Jamieson space is a triangular area of weakness in the upper anterolateral cervical esophagus. – The Killian –Jamieson space is bounded superiorly by the inferior border of the cricopharyngeus, anteriorly by the cricoid cartilage, and inferomedially by the suspensory ligament of the esophagus.
  • 32. – Transient – pouches – Permanent- Diverticula
  • 33.
  • 34.
  • 35. Cervical Esophageal Web • Predominantly from the anterior wall • 3 –8% of patients who undergo upper gastrointestinal barium studies and in 16% of patients at autopsy A web appears on barium studies as a radiolucent bar in the barium pool. 50% - Dysphagia Jet phenomenon