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Surgery for Emphysema
Dr. K Khaing Saw Lwin
Emphysema
• Is characterized by abnormal permanent
enlargement of air spaces distal to the
terminal bronchiole
• Accompanied by destruction of the airspace
walls in the absence of obvious fibrosis
• surgery  palliate emphysema  Severe
Emphysema Refractory to Medical Treatment
1.Bullectomy  with giant bullae
2.LVRS ( lung volume reduction surgery) diffuse
emphysema without bullae
3.lung transplantation Pt with Alpha1 anti-trypsin
deficiency
LUNG VOLUME REDUCTION
SURGERY
• INCREASED WORK OF BREATHING & DYSPNOEA
• Non functional volume occupying area of lung
• Increased dispensability
• ( REMAIN pathologically inflated throughout breathing cycle)
• Destruction of lung tissue
• Loss of elastic recoil
LVRS  IMPROVED
V/QMISMATCH & RELIEVE
SYMPTOMS
Ideal candidates for LVRS
• marked hyperinflation
• significant regions of severe destruction with
other distinct areas of more well-preserved
lung parenchyma
(areas to be removed “target areas”
contrast CT or nuclear medicine perfusion scans)
Methods of surgery
• Median Sternotomy
• Bilateral VATS in the supine patient
(buttressed or unbuttressed staplers)
NETT  National Emphysema Treatment Trial
(pt benefit for LVRS)
• Bronchoscopic LVRS ( VENT trial –
Endobronchial Valve for Emphysema Palliation
Trial)
Dyspnoea Survival
Heterogeneous Low exercise capacity + +
Heterogeneous High exercise capacity +
Homogeneous Low exercise capacity +
Homogeneous High exercise capacity -
• Adult Chest Surgery 2nd Edition
• Sabiston and Spencer Surgery of Chest ,9th
edition
THANK YOU

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Surgery for Emphysema

  • 1. Surgery for Emphysema Dr. K Khaing Saw Lwin
  • 2. Emphysema • Is characterized by abnormal permanent enlargement of air spaces distal to the terminal bronchiole • Accompanied by destruction of the airspace walls in the absence of obvious fibrosis
  • 3. • surgery  palliate emphysema  Severe Emphysema Refractory to Medical Treatment 1.Bullectomy  with giant bullae 2.LVRS ( lung volume reduction surgery) diffuse emphysema without bullae 3.lung transplantation Pt with Alpha1 anti-trypsin deficiency
  • 5. • INCREASED WORK OF BREATHING & DYSPNOEA • Non functional volume occupying area of lung • Increased dispensability • ( REMAIN pathologically inflated throughout breathing cycle) • Destruction of lung tissue • Loss of elastic recoil LVRS  IMPROVED V/QMISMATCH & RELIEVE SYMPTOMS
  • 6. Ideal candidates for LVRS • marked hyperinflation • significant regions of severe destruction with other distinct areas of more well-preserved lung parenchyma (areas to be removed “target areas” contrast CT or nuclear medicine perfusion scans)
  • 7.
  • 8.
  • 9. Methods of surgery • Median Sternotomy • Bilateral VATS in the supine patient (buttressed or unbuttressed staplers) NETT  National Emphysema Treatment Trial (pt benefit for LVRS) • Bronchoscopic LVRS ( VENT trial – Endobronchial Valve for Emphysema Palliation Trial)
  • 10. Dyspnoea Survival Heterogeneous Low exercise capacity + + Heterogeneous High exercise capacity + Homogeneous Low exercise capacity + Homogeneous High exercise capacity -
  • 11. • Adult Chest Surgery 2nd Edition • Sabiston and Spencer Surgery of Chest ,9th edition