2. Emphysema
• Is characterized by abnormal permanent
enlargement of air spaces distal to the
terminal bronchiole
• Accompanied by destruction of the airspace
walls in the absence of obvious fibrosis
3. • surgery palliate emphysema Severe
Emphysema Refractory to Medical Treatment
1.Bullectomy with giant bullae
2.LVRS ( lung volume reduction surgery) diffuse
emphysema without bullae
3.lung transplantation Pt with Alpha1 anti-trypsin
deficiency
5. • INCREASED WORK OF BREATHING & DYSPNOEA
• Non functional volume occupying area of lung
• Increased dispensability
• ( REMAIN pathologically inflated throughout breathing cycle)
• Destruction of lung tissue
• Loss of elastic recoil
LVRS IMPROVED
V/QMISMATCH & RELIEVE
SYMPTOMS
6. Ideal candidates for LVRS
• marked hyperinflation
• significant regions of severe destruction with
other distinct areas of more well-preserved
lung parenchyma
(areas to be removed “target areas”
contrast CT or nuclear medicine perfusion scans)
7.
8.
9. Methods of surgery
• Median Sternotomy
• Bilateral VATS in the supine patient
(buttressed or unbuttressed staplers)
NETT National Emphysema Treatment Trial
(pt benefit for LVRS)
• Bronchoscopic LVRS ( VENT trial –
Endobronchial Valve for Emphysema Palliation
Trial)