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Chromosome number and karyotype
1. Think. Pair. Share:
• Do humans have the greatest number of
chromosomes per cell because we are “the
most intelligent animals on Earth?”
– Why or why not? Write your ideas down in your
notebook
– Share with a partner
– Discuss as a class
5. Be aware that
• So no… we don’t have the greatest amount of
chromosomes and the number of chromosomes
does not relate to intelligence
• Some species of organisms have the same
number of chromosomes: (48)
– Potatoes
– Plums
– Orangutan
– Gorilla
• FOR THE MOST PART each species has a
different number
6. Humans & Chromosomes
• Total of 46 individual chromosomes
– kid gets an equal amount of chromosomes from
mom & dad
• 23 from mom’s egg = 1 set = haploid (1n)
• 23 from dad’s sperm = 1 set = haploid (1n)
8. • Chromosomes come in pairs (2)
• If we know we have 46 individual
chromosomes… how many pairs do we have?
– 46 ÷ 2 = 23 pairs
• Humans have 23 pairs of chromosomes
46
individual 23 pairs
10. • Photograph shows the complete set of
chromosomes for an organism
• Photograph organizes chromosomes by pairs
– Pairs are matched together as homologous
chromosomes
– You can look at a karyotype and identify:
1. Species
2. Sex
Karyotype
12. • Sex chromosomes
– Carries genetic information: male or female
• Autosomes
– Carries genetic information: what the species
will look like
– Information for everything else the cell requires
to live
2 Types of Chromosomes
13. • 2 chromosomes (1 pair) are called sex
chromosomes
– Always the last pair, #23, in the photograph
• They determine your sex
– Female
– Male
• If you are a female you get XX (large in size)
• If you are a male you get XY (X is large but Y is
only ½ the size)
Sex Chromosomes
15. • Other 44 chromosomes (22 pairs) are called
autosomes
– Perfectly matched up
– The first 22 pairs in the photograph
• They tell us what the species will look like, and all
other information required for the cell to live
• Get 1 copy from mom, 1 copy from dad to get a
pair
– 2 copies of each autosome are called homologous
chromosomes; same size, shape and genes
Autosomes
17. Human Karyotyping
• How do you write what you see in a
karyotype of a healthy, normal male
or female? “#, sex chromosomes”
Male = 46, XY
Female = 46, XX
18. • Chromosomes are in ordered pairs
numbered 1-23
– Pairs 1 through 22 are the autosomes
– The last pair, the 23rd pair, are the sex chromosomes
(XX or XY)
• Pairs are matched up as close as possible, based
on their “bands” or “stripes” which are genes
– These are the HOMOLOGOUS chromosomes
How to read a Karyotype
19.
20.
21. • Egg carry 23 chromosomes
– 1 is an X sex chromosome
• Sperm carry 23 chromosomes
– 50:50 chance that the sex chromosome is
X or Y
Who determines the sex of the child?
Sex Determination
Males, fathers
22. KARYOTYPE LAB
• Pass out the packets.
• Go over instructions together.
• PART C in class today
– Materials on front table
23. Homework
• Section 1 review:
– Questions 1-8
– Complete sentences for all except:
• 1 and 5
Editor's Notes
Why or why not? Write your ideas down in your notebookShare with a partnerDiscuss as a class
- Have a student to come up and label this chromosome
Different kinds of organisms or living things have a different number of chromosomes specific to them, we are going to worry about us, humansPlants like a fern, Jurassic Park movies has the highest known chromosome number of any life form 1260 Dog has 78; ant has 2 chromosomesClosest relative to us, the primates (chimpanzee) has 48
Homo sapien = “wise man” Latin, using binomial nomenclature (bicycle = 2 wheels, 2 names)- Haploid = contain only 1 set of chromosomes
The chromosomes you get from each parent are randomly given to you by chance, that’s what those Punnett Squares told us…Diploid = 2 sets of chromosomes; have 2 autosomes for each homologous pair
Always come in pairs unless we have a mutation…. Then we can get 1 or 3… get diseases, deformities, or conditions
- Students might be familiar with it already if they have seen shows like this crime shows, law and order, Greys, someone has a job in a lab to make these karyotypes… use to diagnose disease, look at traits that can be inherited
What species scientific name of dog, cat, worm, flower, etc…. We are Homo sapiens - because of the banding on the chromosomes and the number of the chromosomesSex is it male or female
All of the chromosomes a normal, healthy human should have
What we look like what our species chromosomes look like (4 legs for a dog, humans get 2 arms and 2 legs)
This human karyotype shows the last pair is male with an x and y
So now we can differentiate species 4 legs, or 2 arms and 2 legs, going to have wings/feathers/fins/etc…- Homologous chromosomes= contains a gene for eye color, so will the other chromosome in the homologous pair
#, letters
Centromere = center, middle Chromatid + chromatid = chromosome held by centromere
Red = ? Sex chromosomes what sex is it? Male… how do you know?Blue = ? Autosomes #5, 8, 16, 21
What is this a karyotype of? How do you know?- female, has XX so get two Xs and they are of the same size
Females only have the X so they give an x no matter whatMales could give the X or Y… if they give the x you are a girl, if they gave the y then you are a boy- Show this on the table
Lab will be continued on ThursdayCollect student work in plastic bags w name on it