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VITAMIN A DEFICIENCIES
Hassan Raza
BS Food Science and Technology
Govt. College University,
Faisalabad, Punjab, Pakistan
OUTLINES 1
o Introduction
o History
o Sources
o Deficiency
o Prevalence
o Causes
o Management
o Conclusion
o References
INTRODUCTION 2
o Group of unsaturated organic compound
o Retinol, retinal, retinoic acid, carotenoids, beta carotene
o Multiple function
Tanumihardjo SA (2011).
HISTORY 3
o 1816 by Magendie
o 1912 by Frederick Gowland Hopkins
o 1917 by Elmer McCollum, Lafayette Mendel, Thomas
Burr Osborne
o 1920 name given vitamin A
.
Semba RD (2012).
4
o 1919, Herry Steenbock
o 1931 Paul Karrer
o 1947 David Adriaan van Dorp and Jozef Ferdinand
Arens
.
Wolf, George (2001)
SOURCES 5
o Milk & milk product
o Vegetables
o Naturally occurring
o Meat
SOURCES 7
source Amount provided
carrot 835 μg/100g
Cod liver oil 30000 μg/100g
Beef, fish liver 6500 μg/100g
Sweet potatoes 961 μg/100g
8
Butter 684 μg
Spinach 469 μg/100g
Milk 28 μg/100g
Egg 140 μg/100g
Mango 38 μg/100g
apricot 96 μg/100g
DEFICIENCY 9
o Poor countries
o Rare in developed countries
o Nyctalopia
o Xerophthalmia
o Keratomalacia
o Complete blindness
o Birth defects
o High infection rate
NYCTALOPIA 10
o Greek word
o Difficulty or impossibility to see in low light
o Insufficient adaptation
Quesnel, NM; Lovasik, JV; Ferremi, C; Boileau, M; Ieraci, C (Jun 2004).
XEROPHTHALMIA 11
o Greek word
o Dry eyes
o Lack of tears
o Retinoic acid
Solans, R.; Bosch, J.A.; Galofre, P.; others (2001)
KERATOMALACIA 12
o Epithelial surface
o Un known metabolism
o Loss of goblet cells
Schwartz, Robert (2013).
PREVALENCE 13
o One third under five years
o 670,000 children annually
o 250,000-500,000 developing countries
o Southeast Asia
o Africa
National Institute of Health. 2008.
CAUSES 14
o Iron deficiency
o Malnutrition
o Alcohol consumption
o Liver toxicity
o Hyper urination
http://www.vitaminsall.com
LABORATORY TEST 15
o Serum vitamin A test
o Normal range 20-43 μg/dl
o Corneal culture
MANAGEMENT/TREATMENT 16
o Animal products
o Yellow orange and dark green vegetables
o Fortification
o Supplements
o I.M or I.V solution
CONCLUSION 17
o Vitamin A is important for number of vital body
functions
o Low in take or life style may cause deficiency
o Sever deficiency can cause high mortality rate
o Can be mange by the use of vitamin A rich diet
REFERENCES 18
o Tanumihardjo SA (2011). "Vitamin A: biomarkers of nutrition for
development". The American Journal of Clinical Nutrition
o Semba RD (2012). "On the 'Disco very' of Vitamin A". Annals of Nutrition &
Metabolism
o Wolf, George (2001). "Discovery of Vitamin A". Encyclopedia of Life Sciences.
o http://www.nal.usda.gov/fnic/foodcomp/search
o Quesnel, NM; Lovasik, JV; Ferremi, C; Boileau, M; Ieraci, C (Jun 2004).
"Laser in situ keratomileusis for myopia and the contrast sensitivity function.".
Journal of cataract and refractive surgery
o Solans, R.; Bosch, J.A.; Galofre, P.; others (2001), Salivary and lacrimal gland
dysfunction (sicca syndrome) after radioiodine therapy., Journal of Nuclear
Medicine
19
o Schwartz, Robert. "Dermatologic manifestations of Vitamin A deficiency".
Medscape. Retrieved 13 June 2013
o Office of Dietary Supplements. Vitamin A". National Institute of Health.
Retrieved 8 April 2008
o http://www.vitaminsall.com
Vitamin a deficiences

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Vitamin a deficiences

  • 1.
  • 2. VITAMIN A DEFICIENCIES Hassan Raza BS Food Science and Technology Govt. College University, Faisalabad, Punjab, Pakistan
  • 3. OUTLINES 1 o Introduction o History o Sources o Deficiency o Prevalence o Causes o Management o Conclusion o References
  • 4. INTRODUCTION 2 o Group of unsaturated organic compound o Retinol, retinal, retinoic acid, carotenoids, beta carotene o Multiple function Tanumihardjo SA (2011).
  • 5. HISTORY 3 o 1816 by Magendie o 1912 by Frederick Gowland Hopkins o 1917 by Elmer McCollum, Lafayette Mendel, Thomas Burr Osborne o 1920 name given vitamin A . Semba RD (2012).
  • 6. 4 o 1919, Herry Steenbock o 1931 Paul Karrer o 1947 David Adriaan van Dorp and Jozef Ferdinand Arens . Wolf, George (2001)
  • 7. SOURCES 5 o Milk & milk product o Vegetables o Naturally occurring o Meat
  • 8.
  • 9. SOURCES 7 source Amount provided carrot 835 μg/100g Cod liver oil 30000 μg/100g Beef, fish liver 6500 μg/100g Sweet potatoes 961 μg/100g
  • 10. 8 Butter 684 μg Spinach 469 μg/100g Milk 28 μg/100g Egg 140 μg/100g Mango 38 μg/100g apricot 96 μg/100g
  • 11. DEFICIENCY 9 o Poor countries o Rare in developed countries o Nyctalopia o Xerophthalmia o Keratomalacia o Complete blindness o Birth defects o High infection rate
  • 12. NYCTALOPIA 10 o Greek word o Difficulty or impossibility to see in low light o Insufficient adaptation Quesnel, NM; Lovasik, JV; Ferremi, C; Boileau, M; Ieraci, C (Jun 2004).
  • 13. XEROPHTHALMIA 11 o Greek word o Dry eyes o Lack of tears o Retinoic acid Solans, R.; Bosch, J.A.; Galofre, P.; others (2001)
  • 14. KERATOMALACIA 12 o Epithelial surface o Un known metabolism o Loss of goblet cells Schwartz, Robert (2013).
  • 15. PREVALENCE 13 o One third under five years o 670,000 children annually o 250,000-500,000 developing countries o Southeast Asia o Africa National Institute of Health. 2008.
  • 16. CAUSES 14 o Iron deficiency o Malnutrition o Alcohol consumption o Liver toxicity o Hyper urination http://www.vitaminsall.com
  • 17. LABORATORY TEST 15 o Serum vitamin A test o Normal range 20-43 μg/dl o Corneal culture
  • 18. MANAGEMENT/TREATMENT 16 o Animal products o Yellow orange and dark green vegetables o Fortification o Supplements o I.M or I.V solution
  • 19. CONCLUSION 17 o Vitamin A is important for number of vital body functions o Low in take or life style may cause deficiency o Sever deficiency can cause high mortality rate o Can be mange by the use of vitamin A rich diet
  • 20. REFERENCES 18 o Tanumihardjo SA (2011). "Vitamin A: biomarkers of nutrition for development". The American Journal of Clinical Nutrition o Semba RD (2012). "On the 'Disco very' of Vitamin A". Annals of Nutrition & Metabolism o Wolf, George (2001). "Discovery of Vitamin A". Encyclopedia of Life Sciences. o http://www.nal.usda.gov/fnic/foodcomp/search o Quesnel, NM; Lovasik, JV; Ferremi, C; Boileau, M; Ieraci, C (Jun 2004). "Laser in situ keratomileusis for myopia and the contrast sensitivity function.". Journal of cataract and refractive surgery o Solans, R.; Bosch, J.A.; Galofre, P.; others (2001), Salivary and lacrimal gland dysfunction (sicca syndrome) after radioiodine therapy., Journal of Nuclear Medicine
  • 21. 19 o Schwartz, Robert. "Dermatologic manifestations of Vitamin A deficiency". Medscape. Retrieved 13 June 2013 o Office of Dietary Supplements. Vitamin A". National Institute of Health. Retrieved 8 April 2008 o http://www.vitaminsall.com