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SPIRULINA – AN EXCELLENT
    FUNCTIONAL FOOD

   Dr.K.K.Janardhanan, Ph.D, FNSE, FNABS
                  Professor
        Amala Cancer Research Centre
       Thrissur – 680 555, Kerala, India
         kkjanardhanan@yahoo.com
According to World Health Organization
(WHO) Spirulina is an interesting food rich in
iron and protein which can be administered
to children without risk. WHO also declared it
 as the best food for future.
What is spirulina?
                                It is a blue-green
                              algae
                                It is a simple, one-
                              celled form of algae that
                              thrives in warm, alkaline
                              fresh-water bodies
                                The name "spirulina" is
                              derived from the Latin
                              word for "helix" or "spiral
Produced from two species of cyanobacteria
Arthospira platensis & Arthospira maxicana
History of Spirulina
A German Algae scientist, Dr.Darwin discovered
the existence of the spiral shaped algae and
named it Spirulina



               Dr. Clement of France in 1962 found that the
               Ganimou/Kanembu people living around Lake Chades
               in Africa had stronger bodies than other civilized
               people at that time, despite poor living conditions
               and limited resources.
               Ganimou people   eat a blue green algae found
               floating on the lake's surface. This algae was
               spirulina.
Why Spirulina is known as food of the future




 Spirulina is being developed as the "food of the future"
 because of its amazing ability to synthesize high-quality
 concentrated food more efficiently than any other algae.

 Spirulina contains 65 to 71 percent complete protein, with all
 essential amino acids in perfect balance.
Spirulina won “the best natural food " award
                      in west Germany's International Food Expo.
                      The United Nations has conducted a 5-year
                      toxicology study on Spirulina and found it to
                      be completely non-toxic!




National Aeronautics Space Administration (NASA)
Scientists from USA tested and found that 1 kg
of Spirulina is nutritionally equal to 1,000 kg of
assorted Vegetables & Fruits.
Active ingredients of Spirulina
                                                      Vitamins
        Minerals & Trace elements B1, B2, B3, B6, B12,                     Natural Pigments
            Fe, Mg, Ca, K, Se, etc.            E, K, H and others        Phytocyanin, Chlorophyll,
               in colloidal form                                        Xanthophyll,Beta Carotenes


 Essential fatty acids, like                    8%
gamma-linoleic acid (GLA)        Fa
                                   ts
                                        (5
                                           -   8%
                                                  )

                               Carbohydrates
                                   (15%)                     Proteins
                                                                               Essential
                                                             (60-75%)
                                                                              Amino Acids
        Polysaccharides
           Glycogen
Nutritional value of Spirulina
Spirulina is a highly digestible food, containing 60 to 70% of
protein, without cholesterol and provides all the essential amino
acids, which is a rarity among plant foods.

World's highest beta carotene food- ten times more concentrated
than carrots. It reduces long term health risks and supports body's
defense.

Gamma Linoleic Acid (GLA)- essential fatty acid, important for
healthy bones, normal brain function, growth and development,
stimulation of skin and hair growth and regulation of metabolism
such as lipid
Vitamin B-12 and B Complex- essential for healthy nerves and tissue,
especially for vegetarians.

Minerals & Trace elements-Spirulina is rich in iron, magnesium and
trace minerals, and is easier to absorb than iron supplements.

Unusual phytonutrients - for health and cleansing. Green
(chlorophyll), blue (phycocyanin) and orange (carotenoids) colors
collect the sun's energy and power growth. Chlorophyll is a natural
cleanser and is often referred to as nature's green magic.
Protein         60-63%        3 times higher than beef, fish, or pork;
                              6 times higher than eggs;
                              2 times higher than soybeans
Minerals        7-13%         Including Calcium, Potassium, Magnesium,
                              Zinc and Phosphorus
Fibre           8-10%         4 times higher than flour and corn
Vitamin B12     0.2-0.3mg     3-4 times higher than animal liver

Beta Carotene   140-330mg     5 times higher than carrots,
                              40 times higher than Spinach
Carbohydrate    15-25%

Lipid           6-8%
Chlorophyll     1000-2000mg   More than 20 times higher than wheatgrass
Calcium         130mg         10 times higher than milk

iron            33mg          65 times higher than spinach, 30 times higher
                              than beef, 5 times higher than soy beans
Vitamin   Spirulina     Other source        Possible problems resulting from
                  (6g)                                  insufficient Vitamins
Beta-           12mg        28 bottle of milk Infections, Lack of smell sense
Carotene                    550 pcs apples    Acne, Dermatitis, Eczema
Pro-Vitamin A
B1              0.24mg      16 pcs sardines   Insomnia, Muscle pain, Memory
                            8 bowls of rice   impairment, Acne, Eczema,Reduced
                                              immune resistance, Heart problems
B2              0.24mg      4 whole           Cataracts,Deteriorated vision, Insomnia,
                            potatoes          Stomatitis, Rough and dry skin, Growth
                                              retardation, Eczema, Vaginal itching
B3              1.02mg      8 pcs lemons      Nervousness, Dermatitis

B6              43.2ug      90g bread         Heart diseases, Insomnia, Stomatitis,
                            4 pcs Asparagus Rough and dry skin, Nervousness,
                                              Eczema, Dermatiti
B12             7.2ug       4 pcs eel         Pernicious, Anemia, Ageing fatigue,
                            240g cheese       Menstruation problems
Nutritional value of Spirulina – a comparison
Protein Content



                  Cheese-24.9%



 Peanut-25.8 %                      Milk-3.75 %
                   Spirulina-65 %




 Egg-12.58 %       Chicken 21.39%   Soya-15 %
Beta carotene
    content


                  Apple -110 kg



                                      Green Pea - 5 kg
  Carrot-164g
                 6g Spirulina- 12mg




Cabbage-37kg                            Tomato – 3 kg
                  Chicken – 5.6 kg
Spirulina is an Alkaline food
There are two main types of food: acidic food and alkaline food.
Acidic food - meat, fish, prawns, chicken, bread and flour
Alkaline food - vegetables, milk, seaweeds, fruits and egg white.

Dr. Ragnar Berg of United States - "Everyday's meal should have the
proper proportion of 20% acidic food and 80% alkaline food.“
Medicinal properties of Spirulina

Spirulina offers remarkable health benefits for multiple
reasons. It is rich in iron and protein and also beta
carotene that can overcome eye problems caused by
Vitamin A deficiency. The protein and B-Vitamin
complex makes a major nutritional improvement. It is
an excellent source for essential fatty acid, Gamma
linolic acid (GLA), except for mother’s milk, that helps
to regulate the entire hormone system. Spirulina also
increases breast milk by stimulating lactiferous glands.
Spirulina - A powerful Antioxidant

Spirulina is exceptionally rich in antioxidants that neutralize free-
radicals.

Spirulina contains beta-carotene, tocopherols and phenolic acids,
which are proven to exhibit antioxidant properties.

Phycocyanin is able to scavenge the very dangerous hydroxy radical
and inhibit the oxidation of lipids in the liver and kidneys.

A study demonstrated 71 % antioxidant capacity for the group
taking the Spirulina extract and 54% for the group that did not,
indicating strong antioxidant protection (Miranda.,1998., Brazilian Journal
of Medical and Biological Research).
Spirulina Prevents Cancer

Spirulina has been found useful in cancer prevention.The anti-
mutagenic effect of Spirulina is beneficial in cancer protection and
treatment. Experimental studies have demonstrated its profound
effect on oral cancer. Spirulina was found to reverse oral
leukoplakia in tobacco chewers in Kerala. Complete regression was
observed in 45% of the treated people with a dose of 1g/day for
12 months.
Calcium spirulan isolated from Spirulina platensis, reduced the lung
metastasis of B16-BL6 melanoma cells by inhibiting the tumor
invasion of basement membrane (Mishima et al., 1998., Clinical &
Experimental Metastasis).
Prevent heart damage caused by chemotherapy using Doxorubicin,
without interfering to its anti-tumor activity (Khan et al., 2005.,
Phytotherapy Research)
Spirulina is Cardioprotective

Spirulina is cholesterol free.

Reduces the level of serum LDL (bad cholesterol) and raises HDL
(good cholesterol).


Spirulina cause a significant change in vascular tone by increasing
the synthesis and release of nitric oxide and by decreasing the
synthesis and release of a vasoconstricting substance from the
endothelial cells.
• Spirulina was found to lower cholesterol. Clinical
  studies have shown that thirty healthy men with
  high cholesterol, mild hypertension and
  hyperlipidemia after eating Spirulina for eight
  weeks were found to have lower cholesterol,
  triglycerides and low density lipoprotein (LDL).
  The findings concluded that antioxidants such as
  beta carotene, vitamin C and E, selenium etc
  present in Spirulina offer significant protection
  against cardiovascular diseases
Dietetic therapy with Spirulina for
                  hyperlipemia

Higher total cholesterol levels or neutral fat levels increases blood
viscosity and adheres to vascular walls.


Dietetic therapy - decreasing the consumption of animal proteins, fat,
salt and sugar and increasing their intake of dietary fiber.

Phosphatidyl inositol, a compound lipid existing in Spirulina, was
effective in controlling total cholesterol, LDL cholesterol and neutral
fat levels.
Dietetic therapy with Spirulina for liver
                diseases

The basic treatment for liver diseases consists of rest treatment and
nutritional treatment to protect and repair the liver.

A diet high in protein and vitamins is generally indicated in these
patients in order to improve liver function.

Spirulina which is abundant in vitamins and minerals is one of the
optimum nutritional supplements to improve liver function and protect
the liver.
Dietetic therapy with Spirulina for
                 diabetes mellitus
Diabetes mellitus is a metabolic disease in which carbohydrate
utilization is reduced and blood glucose level is extremely high.
Untreated diabetes mellitus show various symptoms complicated with
diabetic nephropathy, diabetic neuropathy and diabetic retinopathy.
The basic treatment consists of the daily control of blood glucose levels
and calorie control by dietetic therapy.
These patients are required to reduce their food intake and to
supplement balanced amounts of necessary nutrients and dietary fiber.
These conflicting demands are fulfilled only by Spirulina which contains
protein and trace elements abundantly. (Clinical test performed by Chiba
Hygienic College; Literature No.44, 273-277, 1991)
Spirulina is Anti-Viral




Aqueous extracts of Spirulina inhibit the replication of the HIV-1 virus in
human T-cells of the immune system, mononuclear blood cells and
 Langerhans cells of the pancreas.
Japanese scientists discovered an anti-viral compound in Spirulina called
Calcium Spirulan
Calcium Spirulan was found to be active against numerous viruses, including
influenza, herpes, and HIV.
Spirulina for Anemia
One table spoon of Spirulina a day can eliminate iron
deficiency, the most common reason for anemia.
Spirulina is the most digestible protein food,
especially of significant importance to malnourished
people. The health benefits of Spirulina have made it
an excellent food for rapid recovery of children from
malnutrition related diseases.
Spirulina for malnutrition




     Baby saved from malnutrition by spirulina,before and after
                      in Togo, West Africa.
Spirulina is recommended for nursing mothers. For newborns,
malnutrition is often caused by a lack of mother’s milk, the mother
herself often being ill. Spirulina given to the mother helps a return to
lactation and the babies rapidly gain weight.
Spirulina for Athletes




Athletes need extra nutrition.
Spirulina contains GLA which is known to stimulate prostaglandins, master
hormones which regulate every cell of the body, including heart, skin,
circulation and musculature. Correct prostaglandin levels are necessary for
good health and performance.

World Class and Olympic athletes in China and Cuba use spirulina to improve
performance.
Spirulina reducing Pre-menstrual syndrome
                      (PMS)
Studies show women with more severe PMS have unusually low levels
of certain nutrients, so many health experts urge a nutritional
approach.

Three key factors increase the severity of PMS – poor nutrition, lack
of exercise and stress.

Many clinics recommend foods or supplements rich in B-complex,
magnesium, zinc, beta carotene, GLA and other vitamins, minerals and
herbs. By containing many of these nutrients, spirulina is useful in a
PMS reducing plan, and several PMS supplements contain spirulina.
• Spirulina is used as slimming agent in USA. The
  phenylalanine present in Spirulina is said to
  signal the brain to stop hunger pangs leading to
  reduction in food uptake.
• Spirulina is used in balms and anti-wrinkle
  creams. It helps in skin metabolism, cell
  regeneration and skin secretion. Spirulina is
  used in Japan as a safe bio-lipstick and eyeliner.
TAKE HOME MESSAGE

WHO in 1992 declared “Spirulina is a high quality food product,
rich in iron and protein, safe to consume and an excellent
nutrient supplement for children”.

Over 200 scientific studies have demonstrated potential health
benefits of Spirulina.


To maintain your good health and longevity, use spirulina, nature's
gift of superfood to mankind.
Dr.k.k.janardhanan spirulina

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Dr.k.k.janardhanan spirulina

  • 1. SPIRULINA – AN EXCELLENT FUNCTIONAL FOOD Dr.K.K.Janardhanan, Ph.D, FNSE, FNABS Professor Amala Cancer Research Centre Thrissur – 680 555, Kerala, India kkjanardhanan@yahoo.com
  • 2. According to World Health Organization (WHO) Spirulina is an interesting food rich in iron and protein which can be administered to children without risk. WHO also declared it as the best food for future.
  • 3. What is spirulina? It is a blue-green algae It is a simple, one- celled form of algae that thrives in warm, alkaline fresh-water bodies The name "spirulina" is derived from the Latin word for "helix" or "spiral Produced from two species of cyanobacteria Arthospira platensis & Arthospira maxicana
  • 4. History of Spirulina A German Algae scientist, Dr.Darwin discovered the existence of the spiral shaped algae and named it Spirulina Dr. Clement of France in 1962 found that the Ganimou/Kanembu people living around Lake Chades in Africa had stronger bodies than other civilized people at that time, despite poor living conditions and limited resources. Ganimou people eat a blue green algae found floating on the lake's surface. This algae was spirulina.
  • 5. Why Spirulina is known as food of the future Spirulina is being developed as the "food of the future" because of its amazing ability to synthesize high-quality concentrated food more efficiently than any other algae. Spirulina contains 65 to 71 percent complete protein, with all essential amino acids in perfect balance.
  • 6. Spirulina won “the best natural food " award in west Germany's International Food Expo. The United Nations has conducted a 5-year toxicology study on Spirulina and found it to be completely non-toxic! National Aeronautics Space Administration (NASA) Scientists from USA tested and found that 1 kg of Spirulina is nutritionally equal to 1,000 kg of assorted Vegetables & Fruits.
  • 7. Active ingredients of Spirulina Vitamins Minerals & Trace elements B1, B2, B3, B6, B12, Natural Pigments Fe, Mg, Ca, K, Se, etc. E, K, H and others Phytocyanin, Chlorophyll, in colloidal form Xanthophyll,Beta Carotenes Essential fatty acids, like 8% gamma-linoleic acid (GLA) Fa ts (5 - 8% ) Carbohydrates (15%) Proteins Essential (60-75%) Amino Acids Polysaccharides Glycogen
  • 8. Nutritional value of Spirulina Spirulina is a highly digestible food, containing 60 to 70% of protein, without cholesterol and provides all the essential amino acids, which is a rarity among plant foods. World's highest beta carotene food- ten times more concentrated than carrots. It reduces long term health risks and supports body's defense. Gamma Linoleic Acid (GLA)- essential fatty acid, important for healthy bones, normal brain function, growth and development, stimulation of skin and hair growth and regulation of metabolism such as lipid
  • 9. Vitamin B-12 and B Complex- essential for healthy nerves and tissue, especially for vegetarians. Minerals & Trace elements-Spirulina is rich in iron, magnesium and trace minerals, and is easier to absorb than iron supplements. Unusual phytonutrients - for health and cleansing. Green (chlorophyll), blue (phycocyanin) and orange (carotenoids) colors collect the sun's energy and power growth. Chlorophyll is a natural cleanser and is often referred to as nature's green magic.
  • 10. Protein 60-63% 3 times higher than beef, fish, or pork; 6 times higher than eggs; 2 times higher than soybeans Minerals 7-13% Including Calcium, Potassium, Magnesium, Zinc and Phosphorus Fibre 8-10% 4 times higher than flour and corn Vitamin B12 0.2-0.3mg 3-4 times higher than animal liver Beta Carotene 140-330mg 5 times higher than carrots, 40 times higher than Spinach Carbohydrate 15-25% Lipid 6-8% Chlorophyll 1000-2000mg More than 20 times higher than wheatgrass Calcium 130mg 10 times higher than milk iron 33mg 65 times higher than spinach, 30 times higher than beef, 5 times higher than soy beans
  • 11. Vitamin Spirulina Other source Possible problems resulting from (6g) insufficient Vitamins Beta- 12mg 28 bottle of milk Infections, Lack of smell sense Carotene 550 pcs apples Acne, Dermatitis, Eczema Pro-Vitamin A B1 0.24mg 16 pcs sardines Insomnia, Muscle pain, Memory 8 bowls of rice impairment, Acne, Eczema,Reduced immune resistance, Heart problems B2 0.24mg 4 whole Cataracts,Deteriorated vision, Insomnia, potatoes Stomatitis, Rough and dry skin, Growth retardation, Eczema, Vaginal itching B3 1.02mg 8 pcs lemons Nervousness, Dermatitis B6 43.2ug 90g bread Heart diseases, Insomnia, Stomatitis, 4 pcs Asparagus Rough and dry skin, Nervousness, Eczema, Dermatiti B12 7.2ug 4 pcs eel Pernicious, Anemia, Ageing fatigue, 240g cheese Menstruation problems
  • 12. Nutritional value of Spirulina – a comparison Protein Content Cheese-24.9% Peanut-25.8 % Milk-3.75 % Spirulina-65 % Egg-12.58 % Chicken 21.39% Soya-15 %
  • 13. Beta carotene content Apple -110 kg Green Pea - 5 kg Carrot-164g 6g Spirulina- 12mg Cabbage-37kg Tomato – 3 kg Chicken – 5.6 kg
  • 14. Spirulina is an Alkaline food There are two main types of food: acidic food and alkaline food. Acidic food - meat, fish, prawns, chicken, bread and flour Alkaline food - vegetables, milk, seaweeds, fruits and egg white. Dr. Ragnar Berg of United States - "Everyday's meal should have the proper proportion of 20% acidic food and 80% alkaline food.“
  • 15. Medicinal properties of Spirulina Spirulina offers remarkable health benefits for multiple reasons. It is rich in iron and protein and also beta carotene that can overcome eye problems caused by Vitamin A deficiency. The protein and B-Vitamin complex makes a major nutritional improvement. It is an excellent source for essential fatty acid, Gamma linolic acid (GLA), except for mother’s milk, that helps to regulate the entire hormone system. Spirulina also increases breast milk by stimulating lactiferous glands.
  • 16. Spirulina - A powerful Antioxidant Spirulina is exceptionally rich in antioxidants that neutralize free- radicals. Spirulina contains beta-carotene, tocopherols and phenolic acids, which are proven to exhibit antioxidant properties. Phycocyanin is able to scavenge the very dangerous hydroxy radical and inhibit the oxidation of lipids in the liver and kidneys. A study demonstrated 71 % antioxidant capacity for the group taking the Spirulina extract and 54% for the group that did not, indicating strong antioxidant protection (Miranda.,1998., Brazilian Journal of Medical and Biological Research).
  • 17. Spirulina Prevents Cancer Spirulina has been found useful in cancer prevention.The anti- mutagenic effect of Spirulina is beneficial in cancer protection and treatment. Experimental studies have demonstrated its profound effect on oral cancer. Spirulina was found to reverse oral leukoplakia in tobacco chewers in Kerala. Complete regression was observed in 45% of the treated people with a dose of 1g/day for 12 months. Calcium spirulan isolated from Spirulina platensis, reduced the lung metastasis of B16-BL6 melanoma cells by inhibiting the tumor invasion of basement membrane (Mishima et al., 1998., Clinical & Experimental Metastasis). Prevent heart damage caused by chemotherapy using Doxorubicin, without interfering to its anti-tumor activity (Khan et al., 2005., Phytotherapy Research)
  • 18. Spirulina is Cardioprotective Spirulina is cholesterol free. Reduces the level of serum LDL (bad cholesterol) and raises HDL (good cholesterol). Spirulina cause a significant change in vascular tone by increasing the synthesis and release of nitric oxide and by decreasing the synthesis and release of a vasoconstricting substance from the endothelial cells.
  • 19. • Spirulina was found to lower cholesterol. Clinical studies have shown that thirty healthy men with high cholesterol, mild hypertension and hyperlipidemia after eating Spirulina for eight weeks were found to have lower cholesterol, triglycerides and low density lipoprotein (LDL). The findings concluded that antioxidants such as beta carotene, vitamin C and E, selenium etc present in Spirulina offer significant protection against cardiovascular diseases
  • 20. Dietetic therapy with Spirulina for hyperlipemia Higher total cholesterol levels or neutral fat levels increases blood viscosity and adheres to vascular walls. Dietetic therapy - decreasing the consumption of animal proteins, fat, salt and sugar and increasing their intake of dietary fiber. Phosphatidyl inositol, a compound lipid existing in Spirulina, was effective in controlling total cholesterol, LDL cholesterol and neutral fat levels.
  • 21. Dietetic therapy with Spirulina for liver diseases The basic treatment for liver diseases consists of rest treatment and nutritional treatment to protect and repair the liver. A diet high in protein and vitamins is generally indicated in these patients in order to improve liver function. Spirulina which is abundant in vitamins and minerals is one of the optimum nutritional supplements to improve liver function and protect the liver.
  • 22. Dietetic therapy with Spirulina for diabetes mellitus Diabetes mellitus is a metabolic disease in which carbohydrate utilization is reduced and blood glucose level is extremely high. Untreated diabetes mellitus show various symptoms complicated with diabetic nephropathy, diabetic neuropathy and diabetic retinopathy. The basic treatment consists of the daily control of blood glucose levels and calorie control by dietetic therapy. These patients are required to reduce their food intake and to supplement balanced amounts of necessary nutrients and dietary fiber. These conflicting demands are fulfilled only by Spirulina which contains protein and trace elements abundantly. (Clinical test performed by Chiba Hygienic College; Literature No.44, 273-277, 1991)
  • 23. Spirulina is Anti-Viral Aqueous extracts of Spirulina inhibit the replication of the HIV-1 virus in human T-cells of the immune system, mononuclear blood cells and Langerhans cells of the pancreas. Japanese scientists discovered an anti-viral compound in Spirulina called Calcium Spirulan Calcium Spirulan was found to be active against numerous viruses, including influenza, herpes, and HIV.
  • 24. Spirulina for Anemia One table spoon of Spirulina a day can eliminate iron deficiency, the most common reason for anemia. Spirulina is the most digestible protein food, especially of significant importance to malnourished people. The health benefits of Spirulina have made it an excellent food for rapid recovery of children from malnutrition related diseases.
  • 25. Spirulina for malnutrition Baby saved from malnutrition by spirulina,before and after in Togo, West Africa. Spirulina is recommended for nursing mothers. For newborns, malnutrition is often caused by a lack of mother’s milk, the mother herself often being ill. Spirulina given to the mother helps a return to lactation and the babies rapidly gain weight.
  • 26. Spirulina for Athletes Athletes need extra nutrition. Spirulina contains GLA which is known to stimulate prostaglandins, master hormones which regulate every cell of the body, including heart, skin, circulation and musculature. Correct prostaglandin levels are necessary for good health and performance. World Class and Olympic athletes in China and Cuba use spirulina to improve performance.
  • 27. Spirulina reducing Pre-menstrual syndrome (PMS) Studies show women with more severe PMS have unusually low levels of certain nutrients, so many health experts urge a nutritional approach. Three key factors increase the severity of PMS – poor nutrition, lack of exercise and stress. Many clinics recommend foods or supplements rich in B-complex, magnesium, zinc, beta carotene, GLA and other vitamins, minerals and herbs. By containing many of these nutrients, spirulina is useful in a PMS reducing plan, and several PMS supplements contain spirulina.
  • 28. • Spirulina is used as slimming agent in USA. The phenylalanine present in Spirulina is said to signal the brain to stop hunger pangs leading to reduction in food uptake. • Spirulina is used in balms and anti-wrinkle creams. It helps in skin metabolism, cell regeneration and skin secretion. Spirulina is used in Japan as a safe bio-lipstick and eyeliner.
  • 29. TAKE HOME MESSAGE WHO in 1992 declared “Spirulina is a high quality food product, rich in iron and protein, safe to consume and an excellent nutrient supplement for children”. Over 200 scientific studies have demonstrated potential health benefits of Spirulina. To maintain your good health and longevity, use spirulina, nature's gift of superfood to mankind.