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Speculative LAB Building


    basic design approach for
             Energy
               and
           Environment
1.
1 Introduction
 A design approach for a speculative LAB building to
 optimize the green component related to MEP and
 associated architectural components

 2 Alternatives (slides 55-64) are also included to give
 some flexibility on first cost and fast track construction
                                               construction.
1.1
1 1 Building Layout

 The building layout is basically a combination of
 office and open LAB with an approximate 50/50%
 ratio.

 5-Storey Building with 1000 m2 (GFA) per floor
1.2
1 2 Building Base Assumptions
 LAB load is 150 W/m2 all inclusive (except envelope load).
 Office area is Conference Room intense (load shifting)
 Max Energy Intensity
  Biological Lab = 2500MJ/m2
  Office = 500MJ/m2
1.3
1 3 Life Cycle Costing
  A major impact on life cycle costing will be the
  Electrical Tariff and hours of operation and
                                  p
  corporate policy on Total Cost of Ownership
  and Life Cycle p
             y period to be included.
1.4
1 4 BOD Assumptions
              BOD            Office    LAB

                    Min                 4
        ACH                  code
                    Max                 6

                    Min       20       20
       T in C
                    Max       26       26

                    Min       30       30
       RH (%)
                    Max       60       60



    Selection for ACB on 26 C & 50 %
3.
3 Design Approach Overview
 Active Chilled Beams with Primary AHU on Roof
 A ti Chill d B         ith P i            R f
 Office Roof AHU with Total Energy Wheel (Sensible & Latent)
 High Temperature Chilled Water (14 C for AHU @ 16 C for ACB)
 Closed Circuit Cooling Tower with Free Cooling Option or Hybrid
 Cooling Tower.
        g
 LAB Roof AHU with sensible HR only. Alternatively 3 A wheel for
 non Fume Hood Exhaust
 Chiller with VFD
 Others
3.1
3 1 HVAC Design Approach - Primary Air

 Primary AHU – Office with Total Energy Wheel (if
 sufficient return airflow is available based on
 pressurization scheme)   )
3.1
3 1 HVAC Design Approach – Primary Air
 Primary AHU – LAB (Heat Pipe should be controllable type)




 Heat pipe control is achieved through the use of multiple solenoid valves Only
                                                                    valves.
 recommended if light load does exist occasionally that would require re-heat
 otherwise.
3.1
3 1 HVAC Design Approach – Primary Air
Primary AHU – LAB (Optional) 3A wheel with molecular sieve desiccant coating for non Fume Hood/BSC
and other special LAB Exhaust)

     Independently certified wheel performance.
     Equal latent and sensible heat transfer
                                    transfer.
     Highest effectiveness for given size equipment.
     Virtually no cross-contamination (independently certified to be less than 0.04 percent).
     Field adjustable purge section.
     Wheel independently certified to pass NFPA 90A requirements for flame spread and smoke generation
     based upon ASTM E84 fire test method.

Molecular sieve heat wheels have been installed in many laboratory facilities from a multiple-story medical
research f ilit to an animal virology laboratory to hospitals. Cooling requirements h
       h facility t     i l i l       l b t      t h it l C li             i     t have b
                                                                                        been reduced by h lf
                                                                                               d d b half
and heating and humidification requirements by more than two-thirds

NEED TO SEPARATE FUME HOOD AND GENERAL LAB EXHAUST – BENEFITS WOULD BE
HUGE
3.1
3 1 HVAC Design Approach – Primary Air

 Primary LAB AHU – Energy Recovery (evaluate bypass
 benefits/penalty as it relates to added fan energy and
 energy recovery @ outside air conditions)  )
3.
3 HVAC Design Approach – Primary Air

 Primary AHU – LAB Exhaust
3.2
3 2 Design Approach – Lab/Office HVAC

 Interior Zone Cooling with Active Chilled Beams (2-Pipe
 and 2-way discharge)
3.2
3 2 Design Approach – LAB Office HVAC

 Perimeter Option 1 Zone Cooling-Heating with 4-pipe Fan
 Terminals with integrated Slot Diffusers
    Perimeter slot that automatically changes the air discharge pattern to the correct position for
   heating and cooling, and allows 100% of the supply air to be utilized in either application. Auto-
   changeover of air direction from cooling to heating can achieve room set-point significantly faster
   than typical systems
                systems.
3.2
3 2 Design Approach – LAB Office HVAC

 Perimeter Option 2 Active Chilled Beams 4-Pipe
     One Way Discharge
3.2
3 2 Design Approach – LAB Office HVAC

 Perimeter Option 3 Trench Convection Heaters
     Fully Glazed Curtain Wall
3.2
3 2 Design Approach – LAB Office HVAC

 Humidification – Option 1
     Ultrasonic (additional advantage of adiabatic cooling effect if high internal
    load exists that requires cooling during humidification). Electric Energy
                                             humidification)
    consumption = 7% of electric steam
3.2
3 2 Design Approach – LAB Office HVAC

 Humidification – Option 2
    Electric Steam
3.2
3 2 Design Approach – LAB Office HVAC

 Humidification – Option 3
    Gas to Steam
3.2
3 2 Design Approach – LAB Office HVAC

   Heating – Option 1 (if no central hot water or steam is
   available)

Gas or Oil Fired
3.2
3 2 Design Approach – LAB Office HVAC

 Heating – Option 2 (if no central hot water or steam is available)

    Air to Water Heat Pumps (can also be stand-by for cooling in case of 1 Chiller out of order).
    Normally heating will not be an issue in the LAB (except warm-up after shut-down)
3.2 Design Approach – Fume Hood Options
        g pp                     p

      Option                          CAV                               VAV                             HP

                                                           Variable Air Volume (VAV) Fume      High Performance Low
       Type                 Conventional Fume Hood
                                                                            Hood                    Flow Fume Hood

                                                                                               0.2/0.3m/s (40/60fpm)
                                                             0.5m/s (100fpm) @ all sash             457mm (18") sash
                        0.5m/s (100fpm) @ full open sash
Working Principle
                                      position
                                                                   positions with help of             opening using
                                                                sophisticated control system
                                                                                                        ad a ced
                                                                                                        advanced
                                                                                                   aerodynamic designs
    Initial cost                      Low                               High                          Medium

  Running Cost                     Very High                            Low                             Low
Ease of installation,
   commissioning and                 Easy                             Difficult                         Easy
      maintenance
3.2
3 2 Design Approach – Fume Hood Options

 LAB Option 1: CAV Bypass
3.2
3 2 Design Approach – Fume Hood Options

 LAB Option 2: VAV
3.2
3 2 Design Approach – LAB Office HVAC

 LAB Option 3: High Performance Hood (CAV
 recommended for LCC)
3.2
3 2 Design Approach – LAB Office HVAC

 LAB Biological Safety Cabinets (BSC)
    The design of the BSC exhaust system must consider the static pressure of the cabinet with
    dynamic filter loading over time. This static pressure value, generally assumed to be twice the
    initial pressure drop for the new (unloaded) HEPA filters provides for a reasonable life of the
                                                          filters,
    HEPA filter(s). Therefore, the initial balance point for the exhaust is set at twice the initial
    pressure drop that is actually required.
    The same exhaust air system can be used for laboratories, chemical fume hoods, and BSCs.
    This provides an energy-efficient cost-effective installation of back-up exhaust fans. Exhaust for
                       energy-efficient,                                                fans
    these cabinets may be singly vented or manifolded with other biological safety cabinets.
    However, when biological safety cabinets are ducted into manifolded constant-volume or VAV
    systems, the cabinets must be isolated from system airflow fluctuations and static pressure
    changes.
3.2
3 2 Design Approach – LAB Office HVAC

 LAB Biological Safety Cabinets (BSC)
3.2
3 2 Design Approach – LAB Office HVAC

 LAB Clean Benches
3.2
3 2 Design Approach – LAB Office HVAC

 LAB Glove Boxes
3.3
3 3 Design Approach – Solar Radiation


 East-West Side
    Up to 50% Electro-chromic Windows
       SHGC (tinted): 0.09
       U-Value: 1.6 w/m2 K
       VT: 62%
3.3
3 3 Design Approach – Solar Radiation
 North-South Side (recommended as “long” side)
                                   long
    glazing unit combines two optically clear films internally suspended between two lites of
    clear, tinted or reflective glass to create three insulating air spaces. This results in the
    highest glazing unit R-values (between R-4 0 and 7 1) without reliance on inert gas fills
                                               R-4.0     7.1)                                fills.




                           eliminates perimeter
                                   heating
                                   h i
3.3
3 3 Design Approach – Solar Radiation


 South Side
    Architecturally integrated design options (examples)
       Overhangs & Setbacks
       Vertical fins
       Exterior Blinds
3.4
3 4 Design Approach - Roof
 Roof (Extensive Type)
   Green Roof
      U-Value: 0.2 / 2
      U V l 0 2 w/m2 K
3.5
3 5 Design Approach - Cooling
                      Part Load Selection                      COP
Chiller COP           Chilled Water Leaving             14 C
                      Condenser entering water          32 C
  Chillers with VFD                              100%          7.01
                                                               7 01
  (2 x 500 kW         Part Load
                                                 50%           7.69
  indicative)         Chilled Water Leaving             14 C
                      Condenser entering water          28 C
  COP: 7 to 15                                   100%          8.28
                      Part Load
  Condenser water                                50%           9.69

  reset               Chilled Water Leaving             14 C
                      Condenser entering water          24 C
                                                 100%          9.91
                      Part Load
                                                 50%           12.77
                      Chilled Water Leaving             14 C
                      Condenser entering water          20 C
                                                 100%          10.44
                      Part Load
                                                 50%           15.85
COP

                                   14 C
                                                Basis of   Typical Screw @
                                                Design             6
                                   32 C

                                  100%           7.01           5.34         0.76

                                   50%           7.69           7.68         1.00


3.5
3 5 Design Approach - Cooling      14 C
                                                    COP


                                            Basis of        Typical
                                   28 C     Design         Screw @ 6

                                  100%           8.28           6.12         0.74


Chiller COP Comparison             50%           9.69

                                                    COP
                                                                7.75          0.8




(
(recommendation to run             14 C
                                                Basis f
                                                B i of     Typical S
                                                           T i l Screw @


Chillers in parallel is more
                                                Design             6
                                   24 C

                                  100%           9.91           7.00         0.71

efficient than using one large
                    g        g     50%           12.77          7.83         0.61



Chiller – compare 1 x 100 and      14 C
                                          COP




2 x 50%.
                                                Basis of   Typical Screw @
                                                Design             6
                                   20 C

                                  100%           10.44          8.03         0.77

                                   50%           15.85           7.9         0.49


                                 Screw Chiller is water cooled
                                 flooded type. Air Cooled Chiller
                                 COP will have a 0.4 to 0.6 factor
3.6
3 6 Design Approach – Cooling

Free Cooling
  Closed Circuit Cooling Tower. Free Cooling can be enabled at 12-
  14 C WB. That is an additional benefit of HT Chilled Water Design
3.6
3 6 Design Approach – Cooling

Cooling Tower – Option 1 – Closed Circuit
  Cooling Tower with VFD Free cooling operation without the need for an
  intermediate heat exchanger: Chiller turned off
  Dry operation: Conserve water and treatment chemicals, prevent icing and plume
3.6
3 6 Design Approach – Cooling

Cooling Tower – Option 2 - Hybrid
  Cooling Tower with VFD Free cooling operation without the need for an
  intermediate heat exchanger: Chiller turned off (Need to check load profile as it
  relates to ambient to ensure dry operation meets load at any given ambient in
  addition to increased Primary Air Capacity of ACB).
                               y         p y            )
      Combined operation
      Adiabatic operation
      Dry
      D operation
                ti
3.6
3 6 Design Approach – Cooling

Cooling Tower – Option 2 - Hybrid
3.7
3 7 Design Approach – Fans & Motors

HVAC COP
  Vane Axial Fans with VFD
  @ 85%
  Premium Efficiency Motors
3.8
3 8 Design Approach - Interior Options

  Interior Partitions (daylight)
     Montage panels fitted with fluted glass make natural
     daylight accessible to more than 90% of employees.
3.8
3 8 Design Approach – Interior Options

  Interior Partitions – Conference Rooms
     E Glass™ panels mounted in hollow frame extrusions
     to visually and audibly isolate the conference rooms
     from the lobby or perimeter
3.8
3 8 Design Approach – Interior Options

  Daylight
3.9
3 9 Design Approach - Noise

 Noise
  Approach
    - Envelope by others
    - No sound creating components (fans/pumps etc) in
      building except Perimeter Fan Terminals
    - Proper duct design (sizing, sound attenuation/regeneration)
                         (sizing
    - Interior Design
3.10
3 10 Design Approach – Control Optimization

 Controls Optimization
    - Supply Air Reset in airside “free cooling” season Possible
                                    free cooling season.
      down to 10 C with ACB is an additional benefit of ACB.
      Primary air capacity will double at 10 C (basically a free
      cooling effect)
3.10
3 10 Design Approach – Control Optimization

 Controls Optimization
    - Condenser Water Reset (4-5 C above WB) Important for
                                                WB).
      VDF Chiller to achieve maximum efficiency benefits. On
      Standard Chillers there will be limits on how low to reset
      (minimum lift).
3.10
3 10 Design Approach – Control Optimization

 Controls Optimization
    - Chilled Water Reset (up to 16 C)
3.11
3 11 Design Approach – Electrical

 Power Factor Design
    - VFD Screw Chiller can have factory installed Power Factor
      Correction Capacitor (0.95)
3.12
3 12 Design Approach – Lighting

 Lighting
    - See Supplement 1
3.12
3 12 Design Approach – Water Conservation

 Typical Usage in LABS        Office
3.12
3 12 Design Approach – Water Conservation

 Laboratory Equipment Water Use
    Use closed-loop cooling water for equipment cooling instead of open-loop
                  p       g            q p            g             p      p
    (once through).

    Use non-potable water sources.
        non potable

    Use vacuum pumps instead of aspirator fittings at cold-water faucets. One
    way to discourage this is to specify the use of non-threaded faucets, unless
                                                                 faucets
    threaded faucets are required for other laboratory functions
3.12
3 12 Design Approach – Water Conservation

 Process Water Efficiency
    Treat process wastewater so that is can be down-cycled for use
                                               down cycled
    in cooling towers, etc (example AHU condensate)

    Work with scientists and researchers to modify process to
    reduce water use (if feasible and does not interfere with
    science).
3.12
3 12 Design Approach – Water Conservation

 Process Water Efficiency
      Autoclave
        Autoclaves use the steam of water to sterilize and heat-treat laboratory
        equipment in many labs. To produce the steam, water is raised to extremely high
        temperatures. This leftover water is condensed at very high temperatures.
        However, water cannot be discharged at 80C. Thus, chilled water should be used
        to mix with the hot water so the final water temperature is at 50 C. Chilled water
        should not run continuously through the system, regardless of whether or not the
        autoclave was on and producing hot water. The system should be designed and
        programmed so that the chilled water only enters when needed.
3.12
3 12 Design Approach – Water Conservation

 Process Water Efficiency
    Reverse Osmosis
        Reverse Osmosis (R.O.) water is used f many llaboratory experiments. T
        R        O       i (R O ) t i          d for         b t           i    t To
        make the R.O. water, each laboratory that has its own R.O. water system is very
        water intensive. The R.O. purification process is very wasteful; for every liter of
        R.O.
        R O water made 9 more liters are wasted To conserve water the system can
                    made,                    wasted.               water,
        be looped so that the discarded water is recycled back into the machine, and
        processed again.
        Another R.O. related conservation effort can be to use the discarded water as
        non-potable water in other laboratories. Uses for non-potable water include the
        taps within the laboratories or as cooling water for the autoclaves. This water can
        also used to flush toilets.
3.12
3 12 Design Approach – Water Conservation

 Plumbing Fixtures
    Low Flow Fixtures
3.12
3 12 Design Approach – Water Conservation

 Others
    See Supplement 5
4.
4 Design Approach – Next Steps

Customer to confirm period to be considered for TCO evaluation
Finalize Envelope Load
Finalize Plug-Load Summary. Customer to advise diversity to be used based
on their previous experience.
Finalize Min-Max Load profile for each room (zone)
Operating hours to be provided by customer in addition to any N+1
requirements.
Perform TCO calculation for the Basic Design Approach (including Energy
Modeling to include load profile as it relates to ambient DB and WB
             incl de                                             WB.
Review Value Engineering Options (example: deleting Green Roof, EC windows
etc)
Review Alternative Systems options
                            options.
5.
5 Design Approach – Alternate 1 – Office & LAB

 Digital Hybrid System   or   Variable Refrigerant Systems
     DHS (64 HP max)            VRV (54 HP max)
5.
5 Design Approach – Alternate 1 – Office & LAB

   Digital Hybrid System or Variable Refrigerant Systems
    Cassette units were feasible (draft) and ducted units were air
      distribution is critical for rooms with high loads (CR’s and LAB
      Areas)
5.
5 Design Approach – Alternate 1 – Office & LAB

   Digital Hybrid System or Variable Refrigerant Systems
    Optional Heat Recovery (3 pipe) (suitable for LAB with high internal
      load and adjacent office with perimeter heating load)
5.
5 Design Approach – Alternate 1 – Office & LAB

   Digital Hybrid System vs. Variable Refrigerant Systems
    Efficiency comparison (based on manufacturer of DHS - no
       guarantee by the author of this document in its accuracy).
5.
5 Design Approach – Alternate 1 Option 1
                              1-

DHS or VRV with separate DOAS System. Packaged Heat Pump
Rooftop with Hot Gas Reheat for dehumidification and 0 return
Air. Only recommended if light load does exist occasionally that
would require re-heat otherwise.

                                                Radial flow Diffusers
5.
5 Design Approach – Alternate 1 – Option 2

DHS or VRV with separate DOAS System for LAB and Office
combined. Packaged Heat Pump Rooftop with Wheel for total &
sensible recovery. Only recommended if clean exhaust is not more
than 50%



Max 30,000 m3/h
5.
5 Design Approach – Alternate 1 – Option 3

DHS or VRV with separate DOAS System for LAB and Office
combined. Packaged Heat Pump Rooftop with Wheel for total &
sensible recovery. Only recommended if clean exhaust is not more
than 25%



Max 15,000 m3/h
5.
5 Design Approach – Alternate 1

DOAS Control
Office/ Conference Rooms: Co2     LAB: VAV
5.
5 Design Approach – Alternate 1

Energy Recovery – Office only (with option 1 separate LAB unit)
 Office/ Conference Rooms DOAS Unit with Total Energy Wheel if
   air balance (supply : exhaust) does warrant such feature.
6.
6 Design Approach – Alternate 2

Air Cooled Chiller to replace Water Cooled System in Slides 30 -
35 optional with VFD
Thank You for your Attention

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Energy & Environmental Design Approach Speculative Lab Building

  • 1. Speculative LAB Building basic design approach for Energy and Environment
  • 2. 1. 1 Introduction A design approach for a speculative LAB building to optimize the green component related to MEP and associated architectural components 2 Alternatives (slides 55-64) are also included to give some flexibility on first cost and fast track construction construction.
  • 3. 1.1 1 1 Building Layout The building layout is basically a combination of office and open LAB with an approximate 50/50% ratio. 5-Storey Building with 1000 m2 (GFA) per floor
  • 4. 1.2 1 2 Building Base Assumptions LAB load is 150 W/m2 all inclusive (except envelope load). Office area is Conference Room intense (load shifting) Max Energy Intensity Biological Lab = 2500MJ/m2 Office = 500MJ/m2
  • 5. 1.3 1 3 Life Cycle Costing A major impact on life cycle costing will be the Electrical Tariff and hours of operation and p corporate policy on Total Cost of Ownership and Life Cycle p y period to be included.
  • 6. 1.4 1 4 BOD Assumptions BOD Office LAB Min 4 ACH code Max 6 Min 20 20 T in C Max 26 26 Min 30 30 RH (%) Max 60 60 Selection for ACB on 26 C & 50 %
  • 7. 3. 3 Design Approach Overview Active Chilled Beams with Primary AHU on Roof A ti Chill d B ith P i R f Office Roof AHU with Total Energy Wheel (Sensible & Latent) High Temperature Chilled Water (14 C for AHU @ 16 C for ACB) Closed Circuit Cooling Tower with Free Cooling Option or Hybrid Cooling Tower. g LAB Roof AHU with sensible HR only. Alternatively 3 A wheel for non Fume Hood Exhaust Chiller with VFD Others
  • 8. 3.1 3 1 HVAC Design Approach - Primary Air Primary AHU – Office with Total Energy Wheel (if sufficient return airflow is available based on pressurization scheme) )
  • 9. 3.1 3 1 HVAC Design Approach – Primary Air Primary AHU – LAB (Heat Pipe should be controllable type) Heat pipe control is achieved through the use of multiple solenoid valves Only valves. recommended if light load does exist occasionally that would require re-heat otherwise.
  • 10. 3.1 3 1 HVAC Design Approach – Primary Air Primary AHU – LAB (Optional) 3A wheel with molecular sieve desiccant coating for non Fume Hood/BSC and other special LAB Exhaust) Independently certified wheel performance. Equal latent and sensible heat transfer transfer. Highest effectiveness for given size equipment. Virtually no cross-contamination (independently certified to be less than 0.04 percent). Field adjustable purge section. Wheel independently certified to pass NFPA 90A requirements for flame spread and smoke generation based upon ASTM E84 fire test method. Molecular sieve heat wheels have been installed in many laboratory facilities from a multiple-story medical research f ilit to an animal virology laboratory to hospitals. Cooling requirements h h facility t i l i l l b t t h it l C li i t have b been reduced by h lf d d b half and heating and humidification requirements by more than two-thirds NEED TO SEPARATE FUME HOOD AND GENERAL LAB EXHAUST – BENEFITS WOULD BE HUGE
  • 11. 3.1 3 1 HVAC Design Approach – Primary Air Primary LAB AHU – Energy Recovery (evaluate bypass benefits/penalty as it relates to added fan energy and energy recovery @ outside air conditions) )
  • 12. 3. 3 HVAC Design Approach – Primary Air Primary AHU – LAB Exhaust
  • 13. 3.2 3 2 Design Approach – Lab/Office HVAC Interior Zone Cooling with Active Chilled Beams (2-Pipe and 2-way discharge)
  • 14. 3.2 3 2 Design Approach – LAB Office HVAC Perimeter Option 1 Zone Cooling-Heating with 4-pipe Fan Terminals with integrated Slot Diffusers Perimeter slot that automatically changes the air discharge pattern to the correct position for heating and cooling, and allows 100% of the supply air to be utilized in either application. Auto- changeover of air direction from cooling to heating can achieve room set-point significantly faster than typical systems systems.
  • 15. 3.2 3 2 Design Approach – LAB Office HVAC Perimeter Option 2 Active Chilled Beams 4-Pipe One Way Discharge
  • 16. 3.2 3 2 Design Approach – LAB Office HVAC Perimeter Option 3 Trench Convection Heaters Fully Glazed Curtain Wall
  • 17. 3.2 3 2 Design Approach – LAB Office HVAC Humidification – Option 1 Ultrasonic (additional advantage of adiabatic cooling effect if high internal load exists that requires cooling during humidification). Electric Energy humidification) consumption = 7% of electric steam
  • 18. 3.2 3 2 Design Approach – LAB Office HVAC Humidification – Option 2 Electric Steam
  • 19. 3.2 3 2 Design Approach – LAB Office HVAC Humidification – Option 3 Gas to Steam
  • 20. 3.2 3 2 Design Approach – LAB Office HVAC Heating – Option 1 (if no central hot water or steam is available) Gas or Oil Fired
  • 21. 3.2 3 2 Design Approach – LAB Office HVAC Heating – Option 2 (if no central hot water or steam is available) Air to Water Heat Pumps (can also be stand-by for cooling in case of 1 Chiller out of order). Normally heating will not be an issue in the LAB (except warm-up after shut-down)
  • 22. 3.2 Design Approach – Fume Hood Options g pp p Option CAV VAV HP Variable Air Volume (VAV) Fume High Performance Low Type Conventional Fume Hood Hood Flow Fume Hood 0.2/0.3m/s (40/60fpm) 0.5m/s (100fpm) @ all sash 457mm (18") sash 0.5m/s (100fpm) @ full open sash Working Principle position positions with help of opening using sophisticated control system ad a ced advanced aerodynamic designs Initial cost Low High Medium Running Cost Very High Low Low Ease of installation, commissioning and Easy Difficult Easy maintenance
  • 23. 3.2 3 2 Design Approach – Fume Hood Options LAB Option 1: CAV Bypass
  • 24. 3.2 3 2 Design Approach – Fume Hood Options LAB Option 2: VAV
  • 25. 3.2 3 2 Design Approach – LAB Office HVAC LAB Option 3: High Performance Hood (CAV recommended for LCC)
  • 26. 3.2 3 2 Design Approach – LAB Office HVAC LAB Biological Safety Cabinets (BSC) The design of the BSC exhaust system must consider the static pressure of the cabinet with dynamic filter loading over time. This static pressure value, generally assumed to be twice the initial pressure drop for the new (unloaded) HEPA filters provides for a reasonable life of the filters, HEPA filter(s). Therefore, the initial balance point for the exhaust is set at twice the initial pressure drop that is actually required. The same exhaust air system can be used for laboratories, chemical fume hoods, and BSCs. This provides an energy-efficient cost-effective installation of back-up exhaust fans. Exhaust for energy-efficient, fans these cabinets may be singly vented or manifolded with other biological safety cabinets. However, when biological safety cabinets are ducted into manifolded constant-volume or VAV systems, the cabinets must be isolated from system airflow fluctuations and static pressure changes.
  • 27. 3.2 3 2 Design Approach – LAB Office HVAC LAB Biological Safety Cabinets (BSC)
  • 28. 3.2 3 2 Design Approach – LAB Office HVAC LAB Clean Benches
  • 29. 3.2 3 2 Design Approach – LAB Office HVAC LAB Glove Boxes
  • 30. 3.3 3 3 Design Approach – Solar Radiation East-West Side Up to 50% Electro-chromic Windows SHGC (tinted): 0.09 U-Value: 1.6 w/m2 K VT: 62%
  • 31. 3.3 3 3 Design Approach – Solar Radiation North-South Side (recommended as “long” side) long glazing unit combines two optically clear films internally suspended between two lites of clear, tinted or reflective glass to create three insulating air spaces. This results in the highest glazing unit R-values (between R-4 0 and 7 1) without reliance on inert gas fills R-4.0 7.1) fills. eliminates perimeter heating h i
  • 32. 3.3 3 3 Design Approach – Solar Radiation South Side Architecturally integrated design options (examples) Overhangs & Setbacks Vertical fins Exterior Blinds
  • 33. 3.4 3 4 Design Approach - Roof Roof (Extensive Type) Green Roof U-Value: 0.2 / 2 U V l 0 2 w/m2 K
  • 34. 3.5 3 5 Design Approach - Cooling Part Load Selection COP Chiller COP Chilled Water Leaving 14 C Condenser entering water 32 C Chillers with VFD 100% 7.01 7 01 (2 x 500 kW Part Load 50% 7.69 indicative) Chilled Water Leaving 14 C Condenser entering water 28 C COP: 7 to 15 100% 8.28 Part Load Condenser water 50% 9.69 reset Chilled Water Leaving 14 C Condenser entering water 24 C 100% 9.91 Part Load 50% 12.77 Chilled Water Leaving 14 C Condenser entering water 20 C 100% 10.44 Part Load 50% 15.85
  • 35. COP 14 C Basis of Typical Screw @ Design 6 32 C 100% 7.01 5.34 0.76 50% 7.69 7.68 1.00 3.5 3 5 Design Approach - Cooling 14 C COP Basis of Typical 28 C Design Screw @ 6 100% 8.28 6.12 0.74 Chiller COP Comparison 50% 9.69 COP 7.75 0.8 ( (recommendation to run 14 C Basis f B i of Typical S T i l Screw @ Chillers in parallel is more Design 6 24 C 100% 9.91 7.00 0.71 efficient than using one large g g 50% 12.77 7.83 0.61 Chiller – compare 1 x 100 and 14 C COP 2 x 50%. Basis of Typical Screw @ Design 6 20 C 100% 10.44 8.03 0.77 50% 15.85 7.9 0.49 Screw Chiller is water cooled flooded type. Air Cooled Chiller COP will have a 0.4 to 0.6 factor
  • 36. 3.6 3 6 Design Approach – Cooling Free Cooling Closed Circuit Cooling Tower. Free Cooling can be enabled at 12- 14 C WB. That is an additional benefit of HT Chilled Water Design
  • 37. 3.6 3 6 Design Approach – Cooling Cooling Tower – Option 1 – Closed Circuit Cooling Tower with VFD Free cooling operation without the need for an intermediate heat exchanger: Chiller turned off Dry operation: Conserve water and treatment chemicals, prevent icing and plume
  • 38. 3.6 3 6 Design Approach – Cooling Cooling Tower – Option 2 - Hybrid Cooling Tower with VFD Free cooling operation without the need for an intermediate heat exchanger: Chiller turned off (Need to check load profile as it relates to ambient to ensure dry operation meets load at any given ambient in addition to increased Primary Air Capacity of ACB). y p y ) Combined operation Adiabatic operation Dry D operation ti
  • 39. 3.6 3 6 Design Approach – Cooling Cooling Tower – Option 2 - Hybrid
  • 40. 3.7 3 7 Design Approach – Fans & Motors HVAC COP Vane Axial Fans with VFD @ 85% Premium Efficiency Motors
  • 41. 3.8 3 8 Design Approach - Interior Options Interior Partitions (daylight) Montage panels fitted with fluted glass make natural daylight accessible to more than 90% of employees.
  • 42. 3.8 3 8 Design Approach – Interior Options Interior Partitions – Conference Rooms E Glass™ panels mounted in hollow frame extrusions to visually and audibly isolate the conference rooms from the lobby or perimeter
  • 43. 3.8 3 8 Design Approach – Interior Options Daylight
  • 44. 3.9 3 9 Design Approach - Noise Noise Approach - Envelope by others - No sound creating components (fans/pumps etc) in building except Perimeter Fan Terminals - Proper duct design (sizing, sound attenuation/regeneration) (sizing - Interior Design
  • 45. 3.10 3 10 Design Approach – Control Optimization Controls Optimization - Supply Air Reset in airside “free cooling” season Possible free cooling season. down to 10 C with ACB is an additional benefit of ACB. Primary air capacity will double at 10 C (basically a free cooling effect)
  • 46. 3.10 3 10 Design Approach – Control Optimization Controls Optimization - Condenser Water Reset (4-5 C above WB) Important for WB). VDF Chiller to achieve maximum efficiency benefits. On Standard Chillers there will be limits on how low to reset (minimum lift).
  • 47. 3.10 3 10 Design Approach – Control Optimization Controls Optimization - Chilled Water Reset (up to 16 C)
  • 48. 3.11 3 11 Design Approach – Electrical Power Factor Design - VFD Screw Chiller can have factory installed Power Factor Correction Capacitor (0.95)
  • 49. 3.12 3 12 Design Approach – Lighting Lighting - See Supplement 1
  • 50. 3.12 3 12 Design Approach – Water Conservation Typical Usage in LABS Office
  • 51. 3.12 3 12 Design Approach – Water Conservation Laboratory Equipment Water Use Use closed-loop cooling water for equipment cooling instead of open-loop p g q p g p p (once through). Use non-potable water sources. non potable Use vacuum pumps instead of aspirator fittings at cold-water faucets. One way to discourage this is to specify the use of non-threaded faucets, unless faucets threaded faucets are required for other laboratory functions
  • 52. 3.12 3 12 Design Approach – Water Conservation Process Water Efficiency Treat process wastewater so that is can be down-cycled for use down cycled in cooling towers, etc (example AHU condensate) Work with scientists and researchers to modify process to reduce water use (if feasible and does not interfere with science).
  • 53. 3.12 3 12 Design Approach – Water Conservation Process Water Efficiency Autoclave Autoclaves use the steam of water to sterilize and heat-treat laboratory equipment in many labs. To produce the steam, water is raised to extremely high temperatures. This leftover water is condensed at very high temperatures. However, water cannot be discharged at 80C. Thus, chilled water should be used to mix with the hot water so the final water temperature is at 50 C. Chilled water should not run continuously through the system, regardless of whether or not the autoclave was on and producing hot water. The system should be designed and programmed so that the chilled water only enters when needed.
  • 54. 3.12 3 12 Design Approach – Water Conservation Process Water Efficiency Reverse Osmosis Reverse Osmosis (R.O.) water is used f many llaboratory experiments. T R O i (R O ) t i d for b t i t To make the R.O. water, each laboratory that has its own R.O. water system is very water intensive. The R.O. purification process is very wasteful; for every liter of R.O. R O water made 9 more liters are wasted To conserve water the system can made, wasted. water, be looped so that the discarded water is recycled back into the machine, and processed again. Another R.O. related conservation effort can be to use the discarded water as non-potable water in other laboratories. Uses for non-potable water include the taps within the laboratories or as cooling water for the autoclaves. This water can also used to flush toilets.
  • 55. 3.12 3 12 Design Approach – Water Conservation Plumbing Fixtures Low Flow Fixtures
  • 56. 3.12 3 12 Design Approach – Water Conservation Others See Supplement 5
  • 57. 4. 4 Design Approach – Next Steps Customer to confirm period to be considered for TCO evaluation Finalize Envelope Load Finalize Plug-Load Summary. Customer to advise diversity to be used based on their previous experience. Finalize Min-Max Load profile for each room (zone) Operating hours to be provided by customer in addition to any N+1 requirements. Perform TCO calculation for the Basic Design Approach (including Energy Modeling to include load profile as it relates to ambient DB and WB incl de WB. Review Value Engineering Options (example: deleting Green Roof, EC windows etc) Review Alternative Systems options options.
  • 58. 5. 5 Design Approach – Alternate 1 – Office & LAB Digital Hybrid System or Variable Refrigerant Systems DHS (64 HP max) VRV (54 HP max)
  • 59. 5. 5 Design Approach – Alternate 1 – Office & LAB Digital Hybrid System or Variable Refrigerant Systems Cassette units were feasible (draft) and ducted units were air distribution is critical for rooms with high loads (CR’s and LAB Areas)
  • 60. 5. 5 Design Approach – Alternate 1 – Office & LAB Digital Hybrid System or Variable Refrigerant Systems Optional Heat Recovery (3 pipe) (suitable for LAB with high internal load and adjacent office with perimeter heating load)
  • 61. 5. 5 Design Approach – Alternate 1 – Office & LAB Digital Hybrid System vs. Variable Refrigerant Systems Efficiency comparison (based on manufacturer of DHS - no guarantee by the author of this document in its accuracy).
  • 62. 5. 5 Design Approach – Alternate 1 Option 1 1- DHS or VRV with separate DOAS System. Packaged Heat Pump Rooftop with Hot Gas Reheat for dehumidification and 0 return Air. Only recommended if light load does exist occasionally that would require re-heat otherwise. Radial flow Diffusers
  • 63. 5. 5 Design Approach – Alternate 1 – Option 2 DHS or VRV with separate DOAS System for LAB and Office combined. Packaged Heat Pump Rooftop with Wheel for total & sensible recovery. Only recommended if clean exhaust is not more than 50% Max 30,000 m3/h
  • 64. 5. 5 Design Approach – Alternate 1 – Option 3 DHS or VRV with separate DOAS System for LAB and Office combined. Packaged Heat Pump Rooftop with Wheel for total & sensible recovery. Only recommended if clean exhaust is not more than 25% Max 15,000 m3/h
  • 65. 5. 5 Design Approach – Alternate 1 DOAS Control Office/ Conference Rooms: Co2 LAB: VAV
  • 66. 5. 5 Design Approach – Alternate 1 Energy Recovery – Office only (with option 1 separate LAB unit) Office/ Conference Rooms DOAS Unit with Total Energy Wheel if air balance (supply : exhaust) does warrant such feature.
  • 67. 6. 6 Design Approach – Alternate 2 Air Cooled Chiller to replace Water Cooled System in Slides 30 - 35 optional with VFD
  • 68. Thank You for your Attention