Which statement is true with regards to acetylation of histones? Deacetylases remove acetyl groups and increase transcription Acetyl groups stabilize histones The addition of acetyl, methyl, or phosphate groups to histones stimulates transcription Acetyltransferase are enzymes that add acetyl groups Solution Acetyltransferase are the enzymes that add an acetyl group. Acetyltransferase for example Histone acetyltransferases transefer acetyl group onto lysine amino acids on histone proteins. This relaxes the otherwise tightly condensed chromatin and opens up for transcription..