This document provides a detailed overview of migrating from Globus Connect Server version 4 (GCS v4) to version 5 (GCS v5), highlighting key differences in features, management interfaces, and user authentication methods. It outlines the migration process, including the tools and steps necessary to ensure a seamless transition with minimal downtime while preserving existing configurations and UUIDs. Additionally, it discusses best practices for optimizing file transfer performance and supporting non-POSIX storage systems.