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Jen's mother called you in the
clinic telling you that her 18 years
old son is mentally ill.
she ask for your opinion regarding
his odd behavior and thoughts ,
she add that jens stop going to
school because of his illness.
Obsessive-Compulsive Disorder
                  By:
         dr. A.fattah Alsaud
Obsessive-Compulsive Disorder

                               Criteria:
 • obsessive-compulsive disorder is described
   as recurring obsessions or•Subjective (from inside)
                                compulsions
   severe enough to be time consuming or It is
                               •Silly (pt. recog. That
                               untrue)
   cause marked distress or significant
   impairment                  •Unpleasant,
 • An obsession is a recurrent and to resist
                               •Desire intrusive
   thought, feeling, idea, or sensation
 • A compulsion is a conscious, standardized,
   recurring pattern of behavior, such as
   counting, checking, or avoiding.
Some thing in the mind can be:
• Some thing in the mind which is
                     •Idea (thoughts)
  repetitive & keeps coming, usu.
                     •Image (e.g. someone naked,
  Unpleasant & distressing,Pt. try hard to
                     not halluc. )
  resist them but theyImpulse (urge) to do some
                     • keeps coming.
                        thing.
EPIDEMIOLOGY

• The lifetime prevalence estimated at 2 to
  3 %.
• 10 % of outpatients in psychiatric clinics.
• Among adults, men and women are
  equally likely to be affected, but among
  adolescents, boys are more commonly
  affected than are girls.
• Age of onset : 2/3 below age of 25 yrs.
common co morbid psychiatric
diagnoses:
 •   major depressive disorder about 67 %,
 •   social phobia about 25 %,
 •   alcohol use disorders,
 •   specific phobia,
 •   panic disorder,
 •   eating disorders
ETIOLOGY

• Biological Factors
  – Neurotransmitters
     • serotenergic drugs ( decrease serotonin )
     • Neuroimmunology (PANDAS)
  – Brain-Imaging Studies (PET SCAN, MRI
    study)
  – Genetics (twin study, runs in family)
Obsess ional personality
• Behavioral   Factors :
                    feature
  – learning theory   •Exx. Doubt & cautions
                  •Perfectionism
• Personality Factors (personality Dx.)
                  •Over consciousness
• Psychodynamic Factors
                      •Inflexibility & stubbornness
Diagnostic Criteria for
    Obsessive-Compulsive Disorder
A. Either obsessions or compulsions:
• Obsessions as defined by (1), (2), (3), and (4) :
     1. recurrent and persistent thoughts, impulses, or images that are
        experienced, at some time during the disturbance, as intrusive and
        inappropriate and that cause marked anxiety or distress.
     2. the thoughts, impulses, or images are not simply excessive worries
        about real-life problems.
     3. the person attempts to ignore or suppress such thoughts, impulses, or
        images, or to neutralize them with some other thought or action.
     4. the person recognizes that the obsessional thoughts, impulses, or
        images are a product of his or her own mind (not imposed from without
        as in thought insertion(.
•   Compulsions as defined by (1) and (2( :
     1. repetitive behaviors (eg, handwashing, ordering, checking) or mental
        acts (eg, praying, counting, repeating words silently) that the person feels
        driven to perform in response to an obsession, or according to rules that
        must be applied rigidly.
     2. the behaviors or mental acts are aimed at preventing or reducing
        distress or preventing some dreaded event or situation; however, these
        behaviors or mental acts either are not connected in a realistic way with
        what they are designed to neutralize or prevent, or are clearly excessive.
• B. At some point during the course of the
  disorder, the person has recognized that the
  obsessions or compulsions are excessive or
  unreasonable. Note: this does not apply to
  children.
• C. The obsessions or compulsions cause
  marked distress; are time-consuming (take
  more than an hour a day); or significantly
  interfere with the person's normal routine,
  occupational (or academic) functioning, or
  usual social activities or relationships.
• D. If another Axis I disorder is present, the content of
  the obsessions or compulsions is not restricted to it
  (eg, preoccupation with food in the presence of an
  eating disorder; hair pulling in the presence of
  trichotillomania; concern with appearance in the
  presence of body dysmorphic disorder; preoccupation
  with drugs in the presence of a substance use
  disorder; preoccupation with having a serious illness in
  the presence of hypochondriasis; preoccupation with
  sexual urges or fantasies in the presence of a
  paraphilia; or guilty ruminations in the presence of
  major depressive disorder).
• E. The disturbance is not due to the direct effects of a
  substance (eg, a drug of abuse, a medication) or a
  general medical condition.
CLINICAL FEATURES

• many people manage to keep their
  symptoms secret
• Patients with obsessive-compulsive
  disorder often go to physicians other
  than psychiatrists (e.g. pt. visit derma
  clinic for complication of exx cleaning).
• Precipitance: about 50 to 70 percent of
  patients occurs after a stressful event
  ( puperty, menstruation, marriage,
  examination, death of close relative)
• Course: (episodic or chronic)
• Usu. Compulsions is 2ry to obsessions.
• The most common pattern is an
  obsession of contamination, followed by
  washing or accompanied by compulsive
  avoidance of the presumably
  contaminated object.
• The second most common pattern is an
  obsession of doubt, followed by a
  compulsion of checking.
• the third is intrusive obsessional
  thoughts without a compulsion.
• The fourth is the need for symmetry or
  precision, which can lead to a
  compulsion of slowness.
Obsessions

(N = 200)
• Contamination        45%
• Pathological doubt   42%
• Need for symmetry 31%
• Aggressive       28%
• Sexual      26%
• Other       13%
• Multiple obsessions 60%
Compulsions

 (N = 200)
• Checking 63%
• Washing 50%
• Counting 36%
• Need to ask or confess   31%
• Symmetry and precision   28%
• Hoarding 18%
• Multiple comparisons     48%
prognosis

 • About 20 to 30 percent of patients have
   significant improvement in their
   symptoms,
 • 40 to 50 percent have moderate
   improvement,
 • The remaining 20 to 40 percent of
   patients either remain ill or have a
   worsening of their symptoms.
DIFFERENTIAL DIAGNOSIS

• Nl. Preoccupation : e.g. one preoccupied
  about exams.
• Depression
• SCZ (e.g.: delusion, well be accepted by the
  pt. with out resistence).
• Tic Dx. : (involuntary movement )here there is
  no resistance to it,
• Obsessional personality: here the one is not
  distressed by his acts & will not try to resist
  them.
Treatment

• Psychotherapy :
   – Supportive : let the pt. talk about his problem, reassure,
     explain & advice .
   – CBT
   – Behavioral therapy: exposure & response prevention.
• Pharmacotherapy:
   – Minor tranquilizer (anxioletics)
   – Antidepressants :
       • TCA ( clomepramine)
       • SSRI ( paroxetin)
• ECT ( for depression )
• Psychosurgery: cingulotomy ( disconnect fronto-
  thalamic connection to decrease distress & anxiety
  with obsessions )
Thank You
Case:

• Jens is German and 18 years old. He
  stopped going to high school because of
  his illness.
Problem

• When he was almost 15 years old, Jen's
  parents noticed that after his newspaper
  and magazine delivery rounds, Jens
  would wash his hands more and more
  often and for a longer and longer time.
  Eventually he ended up spending more
  than an hour under the shower. When
  asked about it, Jens told his parents that
  he felt as if he were being contaminated
  by a popular women's magazine.
• He also feared that through contact with
  boys from less academic schools, he
  might become like them—"common,
  slimy, impulsive, aggressive, and
  stupid." Because he was afraid that he
  might be touched by such schoolboys in
  the bus, he insisted that his mother take
  him to school every day by car.
• Jens soon came to regard the walls,
  furniture, and other objects in his
  parents' home as contaminated by their
  less educated visitors. Only his own
  room, where no one else was allowed,
  seemed uninfected. He soon came to
  regard entire streets, buildings, shops,
  and playgrounds as contaminated, and
  he often went out of his way to avoid
  passing these places.
• He gave up his beloved tennis and also
  stopped playing on the football team. He
  spent almost all of his spare time in his room
  with the blinds down, sitting for hours in his
  chair doing nothing. He even refused to put
  on his washed and ironed clothing unless his
  mother had washed and ironed it under his
  supervision. In the end he could no longer
  read newspapers and magazines and could
  no longer touch his school books. He soon
  became a complete failure at school because
  he could no longer follow the lessons and no
  longer did any school work.
• Worst of all were his evening rituals in
  the shower, where he spent hours using
  several bottles of shower gel. He would
  clean his fingernails until they bled, and
  his skin became chapped and sore.
  When his parents tried to prevent him
  from showering excessively, he became
  aggressive.
• To their desperate attempts to make him
  realize that his fear of contamination and
  his endless washing were devoid of any
  realistic foundation, he constantly
  responded, "I know it's nonsense, but I
  just have to do it; I can't help it." He was
  often quite desperate and unhappy
  about his situation and kept crying about
  it.
History.

 • Jens grew up as the second of four children. The
   father was an architect, and the mother worked as a
   librarian. His birth and childhood were quite normal.
   From infancy Jens was always very well behaved,
   orderly, and helpful. At school he was ambitious, and
   his grades were above average. He always kept his
   room clean and tidy and did not want playmates to
   come and make it untidy. At about the age of 13 he
   grew a lot in height, and at the age of 14 he was
   already more than 1.8 m tall, with the physical
   appearance of a young man. Before his illness he was
   very keen on sports, especially tennis, football, and
   cycling.
• His 49-year-old father came from a family of
  professional soldiers, with a very strict and
  efficiency-oriented upbringing, and his 50-
  year-old mother came from a similar family
  and had always made very high demands on
  herself. A cousin of the father was reported to
  suffer from a severe compulsion neurosis, but
  otherwise there was no information about
  psychiatric disorders in the family.
Findings

 • On referral Jens appeared shy and
   reticent, with apparent difficulties in
   talking about himself and particularly
   about his emotions. He was aware that
   his obsessions and compulsions were
   his own ideas or impulses and that they
   were nonsensical. Initially he had tried to
   resist them, but eventually he realized
   that he simply could not do it.
• In the beginning giving in to the impulses
  relieved his tensions, but later on it
  became a torture. There was no
  evidence of hallucinatory experiences or
  delusional ideas. His speech was
  normal, and no catatonic features were
  observed. Throughout the interview he
  appeared mildly depressed. No cognitive
  deficiencies were detected, and he was
  fully oriented in all respects.
DISCUSSION

• Jens meets the criteria for an obsessive-compulsive
  disorder with mixed obsessional thoughts and acts.
  For several years he experienced obsessions of
  contamination and compulsions of washing that were
  repetitive and unpleasant, causing severe distress and
  interference with social and individual functioning. He
  acknowledged that the obsessions and compulsions
  originated from his own mind and that they were
  unreasonable. He had initially tried to resist his
  compulsions, but eventually he had to give in to them.
  There is no evidence of primary schizophrenic or
  affective disorders.
• A few depressive symptoms are
  mentioned, but not enough to meet the
  criteria of a depressive episode, and
  such symptoms obviously appear
  secondary to his obsessive-compulsive
  disorder. Exaggerated personality traits
  of an anancastic nature are described,
  but they are not sufficient to meet the
  criteria for a personality disorder, which
  his young age will also hardly allow.
Thanks

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Ocd

  • 1. Jen's mother called you in the clinic telling you that her 18 years old son is mentally ill. she ask for your opinion regarding his odd behavior and thoughts , she add that jens stop going to school because of his illness.
  • 2. Obsessive-Compulsive Disorder By: dr. A.fattah Alsaud
  • 3. Obsessive-Compulsive Disorder Criteria: • obsessive-compulsive disorder is described as recurring obsessions or•Subjective (from inside) compulsions severe enough to be time consuming or It is •Silly (pt. recog. That untrue) cause marked distress or significant impairment •Unpleasant, • An obsession is a recurrent and to resist •Desire intrusive thought, feeling, idea, or sensation • A compulsion is a conscious, standardized, recurring pattern of behavior, such as counting, checking, or avoiding.
  • 4. Some thing in the mind can be: • Some thing in the mind which is •Idea (thoughts) repetitive & keeps coming, usu. •Image (e.g. someone naked, Unpleasant & distressing,Pt. try hard to not halluc. ) resist them but theyImpulse (urge) to do some • keeps coming. thing.
  • 5. EPIDEMIOLOGY • The lifetime prevalence estimated at 2 to 3 %. • 10 % of outpatients in psychiatric clinics. • Among adults, men and women are equally likely to be affected, but among adolescents, boys are more commonly affected than are girls. • Age of onset : 2/3 below age of 25 yrs.
  • 6. common co morbid psychiatric diagnoses: • major depressive disorder about 67 %, • social phobia about 25 %, • alcohol use disorders, • specific phobia, • panic disorder, • eating disorders
  • 7. ETIOLOGY • Biological Factors – Neurotransmitters • serotenergic drugs ( decrease serotonin ) • Neuroimmunology (PANDAS) – Brain-Imaging Studies (PET SCAN, MRI study) – Genetics (twin study, runs in family)
  • 8. Obsess ional personality • Behavioral Factors : feature – learning theory •Exx. Doubt & cautions •Perfectionism • Personality Factors (personality Dx.) •Over consciousness • Psychodynamic Factors •Inflexibility & stubbornness
  • 9. Diagnostic Criteria for Obsessive-Compulsive Disorder A. Either obsessions or compulsions: • Obsessions as defined by (1), (2), (3), and (4) : 1. recurrent and persistent thoughts, impulses, or images that are experienced, at some time during the disturbance, as intrusive and inappropriate and that cause marked anxiety or distress. 2. the thoughts, impulses, or images are not simply excessive worries about real-life problems. 3. the person attempts to ignore or suppress such thoughts, impulses, or images, or to neutralize them with some other thought or action. 4. the person recognizes that the obsessional thoughts, impulses, or images are a product of his or her own mind (not imposed from without as in thought insertion(. • Compulsions as defined by (1) and (2( : 1. repetitive behaviors (eg, handwashing, ordering, checking) or mental acts (eg, praying, counting, repeating words silently) that the person feels driven to perform in response to an obsession, or according to rules that must be applied rigidly. 2. the behaviors or mental acts are aimed at preventing or reducing distress or preventing some dreaded event or situation; however, these behaviors or mental acts either are not connected in a realistic way with what they are designed to neutralize or prevent, or are clearly excessive.
  • 10. • B. At some point during the course of the disorder, the person has recognized that the obsessions or compulsions are excessive or unreasonable. Note: this does not apply to children. • C. The obsessions or compulsions cause marked distress; are time-consuming (take more than an hour a day); or significantly interfere with the person's normal routine, occupational (or academic) functioning, or usual social activities or relationships.
  • 11. • D. If another Axis I disorder is present, the content of the obsessions or compulsions is not restricted to it (eg, preoccupation with food in the presence of an eating disorder; hair pulling in the presence of trichotillomania; concern with appearance in the presence of body dysmorphic disorder; preoccupation with drugs in the presence of a substance use disorder; preoccupation with having a serious illness in the presence of hypochondriasis; preoccupation with sexual urges or fantasies in the presence of a paraphilia; or guilty ruminations in the presence of major depressive disorder). • E. The disturbance is not due to the direct effects of a substance (eg, a drug of abuse, a medication) or a general medical condition.
  • 12. CLINICAL FEATURES • many people manage to keep their symptoms secret • Patients with obsessive-compulsive disorder often go to physicians other than psychiatrists (e.g. pt. visit derma clinic for complication of exx cleaning).
  • 13. • Precipitance: about 50 to 70 percent of patients occurs after a stressful event ( puperty, menstruation, marriage, examination, death of close relative) • Course: (episodic or chronic) • Usu. Compulsions is 2ry to obsessions.
  • 14. • The most common pattern is an obsession of contamination, followed by washing or accompanied by compulsive avoidance of the presumably contaminated object. • The second most common pattern is an obsession of doubt, followed by a compulsion of checking.
  • 15. • the third is intrusive obsessional thoughts without a compulsion. • The fourth is the need for symmetry or precision, which can lead to a compulsion of slowness.
  • 16. Obsessions (N = 200) • Contamination 45% • Pathological doubt 42% • Need for symmetry 31% • Aggressive 28% • Sexual 26% • Other 13% • Multiple obsessions 60%
  • 17. Compulsions (N = 200) • Checking 63% • Washing 50% • Counting 36% • Need to ask or confess 31% • Symmetry and precision 28% • Hoarding 18% • Multiple comparisons 48%
  • 18. prognosis • About 20 to 30 percent of patients have significant improvement in their symptoms, • 40 to 50 percent have moderate improvement, • The remaining 20 to 40 percent of patients either remain ill or have a worsening of their symptoms.
  • 19. DIFFERENTIAL DIAGNOSIS • Nl. Preoccupation : e.g. one preoccupied about exams. • Depression • SCZ (e.g.: delusion, well be accepted by the pt. with out resistence). • Tic Dx. : (involuntary movement )here there is no resistance to it, • Obsessional personality: here the one is not distressed by his acts & will not try to resist them.
  • 20. Treatment • Psychotherapy : – Supportive : let the pt. talk about his problem, reassure, explain & advice . – CBT – Behavioral therapy: exposure & response prevention. • Pharmacotherapy: – Minor tranquilizer (anxioletics) – Antidepressants : • TCA ( clomepramine) • SSRI ( paroxetin) • ECT ( for depression ) • Psychosurgery: cingulotomy ( disconnect fronto- thalamic connection to decrease distress & anxiety with obsessions )
  • 22.
  • 23. Case: • Jens is German and 18 years old. He stopped going to high school because of his illness.
  • 24. Problem • When he was almost 15 years old, Jen's parents noticed that after his newspaper and magazine delivery rounds, Jens would wash his hands more and more often and for a longer and longer time. Eventually he ended up spending more than an hour under the shower. When asked about it, Jens told his parents that he felt as if he were being contaminated by a popular women's magazine.
  • 25. • He also feared that through contact with boys from less academic schools, he might become like them—"common, slimy, impulsive, aggressive, and stupid." Because he was afraid that he might be touched by such schoolboys in the bus, he insisted that his mother take him to school every day by car.
  • 26. • Jens soon came to regard the walls, furniture, and other objects in his parents' home as contaminated by their less educated visitors. Only his own room, where no one else was allowed, seemed uninfected. He soon came to regard entire streets, buildings, shops, and playgrounds as contaminated, and he often went out of his way to avoid passing these places.
  • 27. • He gave up his beloved tennis and also stopped playing on the football team. He spent almost all of his spare time in his room with the blinds down, sitting for hours in his chair doing nothing. He even refused to put on his washed and ironed clothing unless his mother had washed and ironed it under his supervision. In the end he could no longer read newspapers and magazines and could no longer touch his school books. He soon became a complete failure at school because he could no longer follow the lessons and no longer did any school work.
  • 28. • Worst of all were his evening rituals in the shower, where he spent hours using several bottles of shower gel. He would clean his fingernails until they bled, and his skin became chapped and sore. When his parents tried to prevent him from showering excessively, he became aggressive.
  • 29. • To their desperate attempts to make him realize that his fear of contamination and his endless washing were devoid of any realistic foundation, he constantly responded, "I know it's nonsense, but I just have to do it; I can't help it." He was often quite desperate and unhappy about his situation and kept crying about it.
  • 30. History. • Jens grew up as the second of four children. The father was an architect, and the mother worked as a librarian. His birth and childhood were quite normal. From infancy Jens was always very well behaved, orderly, and helpful. At school he was ambitious, and his grades were above average. He always kept his room clean and tidy and did not want playmates to come and make it untidy. At about the age of 13 he grew a lot in height, and at the age of 14 he was already more than 1.8 m tall, with the physical appearance of a young man. Before his illness he was very keen on sports, especially tennis, football, and cycling.
  • 31. • His 49-year-old father came from a family of professional soldiers, with a very strict and efficiency-oriented upbringing, and his 50- year-old mother came from a similar family and had always made very high demands on herself. A cousin of the father was reported to suffer from a severe compulsion neurosis, but otherwise there was no information about psychiatric disorders in the family.
  • 32. Findings • On referral Jens appeared shy and reticent, with apparent difficulties in talking about himself and particularly about his emotions. He was aware that his obsessions and compulsions were his own ideas or impulses and that they were nonsensical. Initially he had tried to resist them, but eventually he realized that he simply could not do it.
  • 33. • In the beginning giving in to the impulses relieved his tensions, but later on it became a torture. There was no evidence of hallucinatory experiences or delusional ideas. His speech was normal, and no catatonic features were observed. Throughout the interview he appeared mildly depressed. No cognitive deficiencies were detected, and he was fully oriented in all respects.
  • 34. DISCUSSION • Jens meets the criteria for an obsessive-compulsive disorder with mixed obsessional thoughts and acts. For several years he experienced obsessions of contamination and compulsions of washing that were repetitive and unpleasant, causing severe distress and interference with social and individual functioning. He acknowledged that the obsessions and compulsions originated from his own mind and that they were unreasonable. He had initially tried to resist his compulsions, but eventually he had to give in to them. There is no evidence of primary schizophrenic or affective disorders.
  • 35. • A few depressive symptoms are mentioned, but not enough to meet the criteria of a depressive episode, and such symptoms obviously appear secondary to his obsessive-compulsive disorder. Exaggerated personality traits of an anancastic nature are described, but they are not sufficient to meet the criteria for a personality disorder, which his young age will also hardly allow.