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Mic
                a


Mica: An integrated web platform to
   support epidemiological studies
         Etienne Morency (emorency@p3g.org)
Mic
       What is Mica ?                                   a
       Mica infrastructure (Maelstrom repository)
       Step 1: Mica Catalogues
       Step 2: Mica Variables
       Step 3: Processing, Integration and Dissemination
       Conclusion




    2                                        4/26/2012
Software Infrastructure                                             Mic
       Mealstrom-Research
        
                                                                    a
         Web portal to document studies that are using our harmonization
            tools
           Operational IT infrastructure that supports management of individual
            harmonization projects
               Integrated – Series of interrelated software (ONYX, OPAL, MICA,
                DataSHIELD and DataSHaPER). Solid “communication routes” with other
                resources (PhenX, Molgenis, DDI):
               Comprehensive – Support all steps of the harmonization process from
                study description to database federation and statistical analysis
               Open source – Based on state-of-the-art and widely used open source
                frameworks, highly customizable and secure, freely available.
       Toolkit to build websites for a study or a consortium
       Easy to install, to manage and extremely customizable (based on
        Drupal and PHP)

    3                                                           4/26/2012
Architecture                                        Mic
                                                    a
 3 architectures that links to the central repository (all
     share core information)


                                            Network


        Hosted
                     Maelstrom-
                     Research


                                                 Independent

 4                                         4/26/2012
Mic
         a


1. Identifying and cataloguing
          participating studies
Study Catalogue               Mic
                              a




9                 4/26/2012
Mic
      a


2. Identifying variables for
             harmonization
Mic
              a


3. Data processing, integration and
                      dissemination
Integration with Opal                                            Mic
                                                                 a
            Kora-gen       UK Biobank             LifeGene
            1800           50,000                 50,000
            participants   participants           participants




     Harmonized                           Harmonized
       Dataset                              Dataset




                                Mica
18                                              4/26/2012
Conclusion                                                      Mic
    Other Features                                             a
        Role-based access control (files, fields, content types)
        Dissemination of Publications/Events/Projects/News
        And many other extensions (calendar, publication
         workflow…)
        Updates
    Ongoing development
        Catalogues (Questionnaires, Access, Biosamples
         Physical Measures) / Follow-up
        Continue the integration with existing tools
        Implement the central repository: Maelstrom-Research
        Translations support
    20                                              4/26/2012

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Maelstrom-Research: Mica 2012 04-25

  • 1. Mic a Mica: An integrated web platform to support epidemiological studies Etienne Morency (emorency@p3g.org)
  • 2. Mic  What is Mica ? a  Mica infrastructure (Maelstrom repository)  Step 1: Mica Catalogues  Step 2: Mica Variables  Step 3: Processing, Integration and Dissemination  Conclusion 2 4/26/2012
  • 3. Software Infrastructure Mic  Mealstrom-Research  a Web portal to document studies that are using our harmonization tools  Operational IT infrastructure that supports management of individual harmonization projects  Integrated – Series of interrelated software (ONYX, OPAL, MICA, DataSHIELD and DataSHaPER). Solid “communication routes” with other resources (PhenX, Molgenis, DDI):  Comprehensive – Support all steps of the harmonization process from study description to database federation and statistical analysis  Open source – Based on state-of-the-art and widely used open source frameworks, highly customizable and secure, freely available.  Toolkit to build websites for a study or a consortium  Easy to install, to manage and extremely customizable (based on Drupal and PHP) 3 4/26/2012
  • 4. Architecture Mic a  3 architectures that links to the central repository (all share core information) Network Hosted Maelstrom- Research Independent 4 4/26/2012
  • 5.
  • 6. Mic a 1. Identifying and cataloguing participating studies
  • 7.
  • 8.
  • 9. Study Catalogue Mic a 9 4/26/2012
  • 10.
  • 11. Mic a 2. Identifying variables for harmonization
  • 12.
  • 13.
  • 14. Mic a 3. Data processing, integration and dissemination
  • 15.
  • 16.
  • 17.
  • 18. Integration with Opal Mic a Kora-gen UK Biobank LifeGene 1800 50,000 50,000 participants participants participants Harmonized Harmonized Dataset Dataset Mica 18 4/26/2012
  • 19.
  • 20. Conclusion Mic  Other Features a  Role-based access control (files, fields, content types)  Dissemination of Publications/Events/Projects/News  And many other extensions (calendar, publication workflow…)  Updates  Ongoing development  Catalogues (Questionnaires, Access, Biosamples Physical Measures) / Follow-up  Continue the integration with existing tools  Implement the central repository: Maelstrom-Research  Translations support 20 4/26/2012