Children are naturally curious and may accidentally ingest poisonous substances found in the home. Common causes of poisoning in children include household products like kerosene, drugs, chemicals, and pesticides. Signs of poisoning can include an acute onset of symptoms in an otherwise healthy child, unexplained involvement of multiple body systems, and conditions like metabolic acidosis, acute renal or liver failure, or arrhythmias without a known heart condition. Clues to the specific toxin ingested may include features like changes in heart rate, breathing rate, temperature, skin appearance, sweating, blood pressure, pupil size, movement coordination, paralysis, spasms, diarrhea, or jaundice.