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POISONING IN 
CHILDREN
Definition of poison, 
toxin, venoms. 
Introduction and 
diagnosis with clues
Poison: 
A substance(solid,liquid or gas), 
which if introduced in the living body, or 
brought into contact to a part therefore, 
will produce ill health or death, by its 
constitutional or local effects or both.
Toxins: 
Poisons produced by a natural 
biological process. 
Venom: 
Toxins that are injected by a bite 
or sting to cause their effect.
Poisoning in children 
Children are curious and explore their 
world with all their senses, including taste. As a 
result, the home and its surroundings can be a 
dangerous place where poisonous substances are 
inadvertently ingested. 
Common causes of poisoning in children are 
household products including kerosene oil, drugs, 
chemicals(corrosives) and pesticides.
Clues to poisoning in children: 
• Acute onset of symptoms in an otherwise 
healthy child. 
• Unexplained multisystem involvement. 
• Metabolic acidosis 
• Acute renal failure 
• Acute liver failure 
• Arrythmias in a child with no known cardiac 
illness.
Clues to nature of poisoning:
Features Toxins 
Bradycardia Digitalis,organophosphorus,betablockers,opioids 
Tachycardia Atropine,salicylates,amphetamine 
Tachypnoea Salicylates,ethylene glycol 
Apnea Barbiturates,alcohol,opioids 
Hypothermia Barbiturates 
Fever Atropine,organophoshphorus,salicylates,theophylline,quinine 
Flushed skin Carbon monoxide,cyanide 
Cyanosis Methemoglobinemia,carbon monoxide 
Diaphoresis Organophosphates,salicylates 
Hypertension Phenylpropanolamine, anticholinergics 
Miosis Organophosphates,opioids,barbiturates 
Mydriasis Atropine,amphetamines,alcohol 
Ataxia Phenytoin,alcohol,barbitutares, 
anticholinergics 
Paralysis Botulism, heavy metals 
Spasms Strychinne 
Diarrhoea Arsenic 
Jaundice Acetaminophen,carbon tetrachloride
Poisons introduction
Poisons introduction

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Poisons introduction

  • 2. Definition of poison, toxin, venoms. Introduction and diagnosis with clues
  • 3. Poison: A substance(solid,liquid or gas), which if introduced in the living body, or brought into contact to a part therefore, will produce ill health or death, by its constitutional or local effects or both.
  • 4. Toxins: Poisons produced by a natural biological process. Venom: Toxins that are injected by a bite or sting to cause their effect.
  • 5. Poisoning in children Children are curious and explore their world with all their senses, including taste. As a result, the home and its surroundings can be a dangerous place where poisonous substances are inadvertently ingested. Common causes of poisoning in children are household products including kerosene oil, drugs, chemicals(corrosives) and pesticides.
  • 6. Clues to poisoning in children: • Acute onset of symptoms in an otherwise healthy child. • Unexplained multisystem involvement. • Metabolic acidosis • Acute renal failure • Acute liver failure • Arrythmias in a child with no known cardiac illness.
  • 7. Clues to nature of poisoning:
  • 8. Features Toxins Bradycardia Digitalis,organophosphorus,betablockers,opioids Tachycardia Atropine,salicylates,amphetamine Tachypnoea Salicylates,ethylene glycol Apnea Barbiturates,alcohol,opioids Hypothermia Barbiturates Fever Atropine,organophoshphorus,salicylates,theophylline,quinine Flushed skin Carbon monoxide,cyanide Cyanosis Methemoglobinemia,carbon monoxide Diaphoresis Organophosphates,salicylates Hypertension Phenylpropanolamine, anticholinergics Miosis Organophosphates,opioids,barbiturates Mydriasis Atropine,amphetamines,alcohol Ataxia Phenytoin,alcohol,barbitutares, anticholinergics Paralysis Botulism, heavy metals Spasms Strychinne Diarrhoea Arsenic Jaundice Acetaminophen,carbon tetrachloride