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Company
Profile
Company Overview
Subsidiaries
Products
Certificate & Manufacture
Contents 01
02
03
04
Yinlai Li, CEO
• Master degree in Molecular Genetics,
Hangzhou Normal University
• Serial entrepreneur for 2 IVD upstream
material enterprises
• Over 10 years experience in IVD upstream
industry
• “Visionary, pragmatic, generous, reliable,
strong in execution”
Company Overview
A professional developer, manufacturer and solution provider of biomedical core raw materials
300+
Employees
4
Subsidiaries
SO13485 & CE
Certified
25
Authorized patents
$ 3 million+
Annually R&D Cost
Financing
Series A+ financing
(by LYFE capital)
Service Science, See the Future
Subsidiaries
• New site in Biopolis, close to research
and biotech clients
• GMP space for R&D and production of
CGT upstream materials
• Co-development and CDMO services
available
• Extending sales network to the
Southeast Asia
• Over 100 products covering
enzymes, cytokines, Ag/Ab
• Up to 10kg product per year
• Biological enzyme 200L/day
• Extraction reagent 1KG/day
• Mag-Microbeads 3KG/day
• ProteinA chromatography
media single batch 500L
• Up to 40,000L media yearly
• 4 automatic product lines
• Assembly up to 2 million POCT
products per day
Bioeast
Acnovia BiogenMicro
Aichek Bioeast SG/US
260
m²
2700
m²
6910
m²
8250
m²
3200
m²
Hangzhou
Suzhou Biopolis
> 20000
m²
Subsidiaries
Biomedical Core Raw Materials
POCT
Integrated Solutions
CGT upstream
Integrated Solutions
Chromatographic
Media Solutions
POCT
Products
Ab/Ag,
Cytokines
IVD Nano
Microbeads
Chromatographic Media
Hangzhou Bioeast Biotech is a global supplier of biomedical core raw materials and integrated solutions,
Hangzhou Aichek Medical Technology is the global service supplier of POCT integrated solution.
Hangzhou Acnovia Biosystems is the service provider of cell therapy, gene therapy and mRNA overall solution.
Suzhou BiogenMicro is a protein purification solution provider, supply Chromatographic products
Subsidiaries
Subsidiaries
Products
Dispersive
Model
Sandwich
Model
Centralized
Model
Magnetic Beads
concentration
Enzymes
Products
Multi molecular enzymes
Meet needs of amplification and NGS for various molecular diagnostics
Comparison of probe method hot start enzyme qPCR
Taq enzyme、UDG enzyme
DNA Testing
Reverse transcriptase, RI inhibitors
RNA testing
High-fidelity enzymes, T4 ligase, T4 PNK
NGS testing
Bsu、SSB、Bst、phi29
Isothermal amplification
Highly reversible direct amplification enzyme
Sample extraction for Fast Detection
Enzyme-derived products and molecular diagnostic auxiliary products
Enzyme premixes, molecular enzyme-related
kits, and
NGS library building kits, etc.
Enzyme premixes, molecular enzyme-related kits,
and
NGS library building kits, etc.
Premixes, NGS kits, etc. for research users Lyophilizable/Dryable Products and Services
Extraction reagents for viral DNA/RNA, gDNA, RNA, cf-DNA/ ct-
DNA, etc.
Molecular
Latex Microspheres & Fluorescence Microspheres
Products
ST2, AMH, G17, 25-OH-VD
and other projects domestic
customers market share of
about 50%
G-17, D-D, SAA program
antigens have covered 30% of
the national market
27 series
~500
products
Cardiac
Tumor
Other
Gastroi
ntestin
al
Inflam
mation
Drug of
abuse
Blood
clots
Respira
tory
Antigen&Antibody
GMP Grade Core Material for CGT & mRNA Therapy
Products
星汉德生物
Cell Therapy
30+ Prodcts
Antibody
CD3、CD28
Cytokines
CAR-T CAR-NK
QC Kit
Residue Detection Kit
Reference Customers
Magnetic beads
T、NK Beads
Gene Therapy
10+Products
Elisa Kit
Rapid Test Kit Benzonase Nuclease
Reference Customers
AAV Antibody
PrepareTemplate
mRNA
Synthesis
Capping
Tailing E.coli Poly(A) Polymerase
DNase l
Murine RNase Inhibitor
Thermostable Inorganic Pyrophosphatese
T7 RNA Polymerase
BSA I
Single stranded capping enzyme
mRNA Cap 2 ˊ-O-M ethyltransferase
Raw Enzymes
Ø The first single-chain capping enzyme system launched in China
BSA - Enzyme activity detection T7 RNA Polymerase - transcription effect comparison for
different lengths of RNA
Cap0 RNA percentage comparison in different temprature
25℃ 30℃ 35℃ 40℃ 45℃ 50℃
vaccinia
capping
enzyme
51% 78% 93% 94% 91% 19%
Single
stranded
capping
enzyme
74% 90% 94% 94% 89% 87%
DNase l- DNA digestion Comparison
GMP Grade Core Material for CGT & mRNA Therapy
Products
mRNA Therapy
Affinity Chromatography
Ion Exchange Chromatography
Hydrophobic Interaction Chromatography
Gel Filtration Chromatography
Multimodal Chromatography
BiogenMicro supplies Chromatographic Solutions
Products
The 2nd Generation BiogCapTM Agarose
High stiffness & Low Back-Pressure
BiogCapTM Large Pore size Agarose
Aichek is a global POCT integrated solution provider
Products
l Drug of Abuse Tests( Urine, Oral Fluid, Hair)
l Infectious Diseases(HIV, HCV, HbsAg, H.pylori)
l Respiratory Diseases(Covid-19, Flu A+B, RSV)
l Tumor Markers(FOB, PSA)
l Cardiovascular Diseases(CTNI, CK-MB, MYO)
l Fertility(HCG, LH)
Rapid Test CDMO
l Rapid Tests
l Immunoturbidity(HbA1c, SAA etc)
l Immunofluorescence Tests(Coming soon)
l CLIA(Coming soon)
l Product design & development
l Quality system construction & counseling
l Commissioned declare registration
l Commercial contract manufacturing service
Certificate and Manufacture
Certificate
Bioeast Workshop
Certificate and Manufacture
Aichek Workshop
Sample Pad Handling Machine
1unit
Fully-Automatic NC Membrane
Dispensing Machine 5units
Fully-automatic Conjugate-pad
Dispensing Machine 6units
Oven 12units
~2400 m2
100,000 Class clean workshop Automatic Cassette Assembly
Machine*6units
Certificate and Manufacture
Hello To The World
Thank you for
listening

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Bioeast Company Profile.pdf

  • 2. Company Overview Subsidiaries Products Certificate & Manufacture Contents 01 02 03 04
  • 3. Yinlai Li, CEO • Master degree in Molecular Genetics, Hangzhou Normal University • Serial entrepreneur for 2 IVD upstream material enterprises • Over 10 years experience in IVD upstream industry • “Visionary, pragmatic, generous, reliable, strong in execution” Company Overview A professional developer, manufacturer and solution provider of biomedical core raw materials 300+ Employees 4 Subsidiaries SO13485 & CE Certified 25 Authorized patents $ 3 million+ Annually R&D Cost Financing Series A+ financing (by LYFE capital) Service Science, See the Future
  • 4. Subsidiaries • New site in Biopolis, close to research and biotech clients • GMP space for R&D and production of CGT upstream materials • Co-development and CDMO services available • Extending sales network to the Southeast Asia • Over 100 products covering enzymes, cytokines, Ag/Ab • Up to 10kg product per year • Biological enzyme 200L/day • Extraction reagent 1KG/day • Mag-Microbeads 3KG/day • ProteinA chromatography media single batch 500L • Up to 40,000L media yearly • 4 automatic product lines • Assembly up to 2 million POCT products per day Bioeast Acnovia BiogenMicro Aichek Bioeast SG/US 260 m² 2700 m² 6910 m² 8250 m² 3200 m² Hangzhou Suzhou Biopolis > 20000 m² Subsidiaries
  • 5. Biomedical Core Raw Materials POCT Integrated Solutions CGT upstream Integrated Solutions Chromatographic Media Solutions POCT Products Ab/Ag, Cytokines IVD Nano Microbeads Chromatographic Media Hangzhou Bioeast Biotech is a global supplier of biomedical core raw materials and integrated solutions, Hangzhou Aichek Medical Technology is the global service supplier of POCT integrated solution. Hangzhou Acnovia Biosystems is the service provider of cell therapy, gene therapy and mRNA overall solution. Suzhou BiogenMicro is a protein purification solution provider, supply Chromatographic products Subsidiaries Subsidiaries
  • 7. Enzymes Products Multi molecular enzymes Meet needs of amplification and NGS for various molecular diagnostics Comparison of probe method hot start enzyme qPCR Taq enzyme、UDG enzyme DNA Testing Reverse transcriptase, RI inhibitors RNA testing High-fidelity enzymes, T4 ligase, T4 PNK NGS testing Bsu、SSB、Bst、phi29 Isothermal amplification Highly reversible direct amplification enzyme Sample extraction for Fast Detection Enzyme-derived products and molecular diagnostic auxiliary products Enzyme premixes, molecular enzyme-related kits, and NGS library building kits, etc. Enzyme premixes, molecular enzyme-related kits, and NGS library building kits, etc. Premixes, NGS kits, etc. for research users Lyophilizable/Dryable Products and Services Extraction reagents for viral DNA/RNA, gDNA, RNA, cf-DNA/ ct- DNA, etc. Molecular
  • 8. Latex Microspheres & Fluorescence Microspheres Products ST2, AMH, G17, 25-OH-VD and other projects domestic customers market share of about 50% G-17, D-D, SAA program antigens have covered 30% of the national market 27 series ~500 products Cardiac Tumor Other Gastroi ntestin al Inflam mation Drug of abuse Blood clots Respira tory Antigen&Antibody
  • 9. GMP Grade Core Material for CGT & mRNA Therapy Products 星汉德生物 Cell Therapy 30+ Prodcts Antibody CD3、CD28 Cytokines CAR-T CAR-NK QC Kit Residue Detection Kit Reference Customers Magnetic beads T、NK Beads Gene Therapy 10+Products Elisa Kit Rapid Test Kit Benzonase Nuclease Reference Customers AAV Antibody
  • 10. PrepareTemplate mRNA Synthesis Capping Tailing E.coli Poly(A) Polymerase DNase l Murine RNase Inhibitor Thermostable Inorganic Pyrophosphatese T7 RNA Polymerase BSA I Single stranded capping enzyme mRNA Cap 2 ˊ-O-M ethyltransferase Raw Enzymes Ø The first single-chain capping enzyme system launched in China BSA - Enzyme activity detection T7 RNA Polymerase - transcription effect comparison for different lengths of RNA Cap0 RNA percentage comparison in different temprature 25℃ 30℃ 35℃ 40℃ 45℃ 50℃ vaccinia capping enzyme 51% 78% 93% 94% 91% 19% Single stranded capping enzyme 74% 90% 94% 94% 89% 87% DNase l- DNA digestion Comparison GMP Grade Core Material for CGT & mRNA Therapy Products mRNA Therapy
  • 11. Affinity Chromatography Ion Exchange Chromatography Hydrophobic Interaction Chromatography Gel Filtration Chromatography Multimodal Chromatography BiogenMicro supplies Chromatographic Solutions Products The 2nd Generation BiogCapTM Agarose High stiffness & Low Back-Pressure BiogCapTM Large Pore size Agarose
  • 12. Aichek is a global POCT integrated solution provider Products l Drug of Abuse Tests( Urine, Oral Fluid, Hair) l Infectious Diseases(HIV, HCV, HbsAg, H.pylori) l Respiratory Diseases(Covid-19, Flu A+B, RSV) l Tumor Markers(FOB, PSA) l Cardiovascular Diseases(CTNI, CK-MB, MYO) l Fertility(HCG, LH) Rapid Test CDMO l Rapid Tests l Immunoturbidity(HbA1c, SAA etc) l Immunofluorescence Tests(Coming soon) l CLIA(Coming soon) l Product design & development l Quality system construction & counseling l Commissioned declare registration l Commercial contract manufacturing service
  • 15. Aichek Workshop Sample Pad Handling Machine 1unit Fully-Automatic NC Membrane Dispensing Machine 5units Fully-automatic Conjugate-pad Dispensing Machine 6units Oven 12units ~2400 m2 100,000 Class clean workshop Automatic Cassette Assembly Machine*6units Certificate and Manufacture
  • 16. Hello To The World