2. Rh - no D antigen on the RBC Rh+ has the D antigen on the RBC A potential problem exists when an Rh- mother and an Rh+ father conceive a child who is Rh+
6. Prevention Screening on first prenatal visit history blood test antibody screen indirect coombs-measures the # of antibodies in the maternal blood
7. Preventive Measures If not sensitized we want to keep her that way Give Rhogam at 28 weeks Give Rhogam if any episodes of bleeding Give Rhogam post partum if baby is Rh+ and mom is not sensitized
8. RhoGam Rh+ antibodies Temporary passive immunity Give within 72 hours of birth IM into the deltoid Kleihauer-Bletke test
9. ABO Incompatibility #1 #2 Genotype Blood type A A AA A A B AB AB A O AO A B A AB AB B B BB B B O BO B O O OO O
10. Occurs in 20% of pregnancies Most cases are limited to a type O mother who has a A or B fetus The B fetus of an A mom and the A fetus of a B mother are occasionally affected O infants because they have NO antigenic sites are never affected regardless of the mom’s blood type
11. Anti A and Anti B antibodies are naturally occurring, women are naturally exposed to the A and B antigens through the foods they eat and through exposure to infection by gram negative bacteria As a result some women have high serum anti A and anti B titers before they get pregnant, which will then cross the placenta and produce hemolysis of fetal RBC’s
12. No antepartaltreatment Nurse should note if potential exists Occasionally the affected newborn may need bililights or exchange transfusion