Now a days everybody wants evidence or proof for any purpose.so govt.of india introduces AYUSH research portal for the devalopment and taking awareness regarding ayurveda where it consists of clinical trial and pre-clinical trial data.

1. Assignment-3
Collection of Research data
done on Ayurvedic Herbal
medicines
Presented to:
DR., S. M .TRIPATHI
(MD)
Presented by:
D. Gnana bhaskar
Reg no:16TMM2364
MS(Pharm)2nd SEM

2. Comparative clinical evaluation of herbal formulation with
multivitamin formulation for learning and memory enhancement

Jigna Shah *1, Ramesh Goyal 2
1 Shri Sarvajanik Pharmacy College, near arvind baug, Mehsana, Gujarat, India. 2 The
Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, India.
Vol.3 Issue 1, January-March 2010 ISSN 0974-2441, Asian Journal of Pharmaceutical and Clinical Research
Data suggest that both PHF and MV supplementation improves learning
and memory as compared to placebo in healthy young subjects. PHF
appears to be more active than MV. Both the drugs might be enhancing
learning and memory due to their antioxidant property or by contributing
to the production of important brain neurotransmitters such as
acetylcholine, adrenal hormones, steroids and cortisone or by
maintaining adequate levels of various micronutrients, which ultimately
affect mental functions and enhance learning abilities.
PHF (Tonix Healthcare, Ahmedabad, India)
and MV (Ami Healthcare, Ahmedabad, India).
PHF is polyherbal formulation containing
ashwagandha, jatamansi, sarpagandha,
shankhpushpi, shatavari, amalki, kauch bij
extract, khurasani ajmo, shilajit, mukta shukhti
pishti and praval pishti. MV is vitamin B
complex capsule containing vitamin B1 (10
mg), vitamin B2 (10 mg), vitamin B6 (3 mg),
vitamin B12 (15 µg), niacinamide (100 mg),
calcium pantothenate (50 mg) and folic acid
(1.5 mg), ascorbic acid (150 mg), biotin (100
µg).
About the formulation Conclusion

3. “Vasuliv Syrup
Extract of Glycyrrhiza glabra (Yashtimadhu) root 6,
Phyllanthus niruri (Bhumyamalaki) whole plant 7,
Boerhaavia diffusa (Punarnava) root 8, Eclipta alba
(Bhringraj) whole plant 9, Terminalia belerica (Bibhitaki)
fruit 10, Terminalia chebula (Haritaki) fruit 11, Picrorhiza
kurroa (Kutaki) root 12, Tephrosia purpurea (Sharpunkh)
whole plant 13, Cichorium intybus (Kasni) seed 14 and
Andrographis paniculata (Kalmegh) aerial
Pharmacological investigation of Polyherbal formulation on Carbon
tetrachloride (CCl4)-induced liver damage in wistar rats Vasuliv Syrup
1Vasu Research Centre, A Division of Vasu Healthcare Pvt. Ltd., 896/A, G.I.D.C., Makarpura, Vadodara – 390 010, Gujarat,
India.
 2Department of Pharmacognosy and Phytochemistry, Shri B. M. Shah College of Pharmaceutical Education and Research,
Dhansura road, College campus, Modasa – 383 315, Gujarat, India.
Hardik Soni1*, Priyanka Desai2, Natvarlal Patel2 and Ghanshyam Patel1
www.ssjournals.com ISSN: 2277-3312 Journal DOI:10.7439/ijpr
International Journal of Pharmacological Research
Conclusion
On the basis of study data, it can be concluded that Polyherbal
formulation (Vasuliv Syrup) has promising hepatoprotective
activity against CCl4-induced liver damage. It can be employed
as safe and effective treatment for hepato-toxicity or liver
damage.
About the formulation Conclusion

4. Safety evaluation of mercury based Ayurvedic formulation
(Sidh Makardhwaj) on brain cerebrum, liver & kidney in rats
Indian J Med Res 139, April 2014, pp 610-618
Department of Pharmacology, All India Institute of Medical Sciences & *Department of AYUSH, Ministry of Health & Family Welfare,
Government of India, New Delhi, India.
Gajendra Kumar, Amita Srivastava, Surinder Kumar Sharma* & Yogendra
Kumar Gupta
Sidh Makardhwaj is a popular Kupipakwa rasayan,
prepared with swarna (gold), parada (mercury), gandhaka
(sulphur) in a specific ratio (1:8:24) mentioned in Ayurvedic
Formulary of India1. It has been used in the Indian Systems of
Medicine for centuries with claimed efficacy and safety for the
treatment of rheumatoid arthritis, neurological disorders, as a
rasayana for vigour and longevity of .life. It is prepared by a
specific process of constant heating for more than 24 h converting
it in a stable compound (mercury sulphide).
The findings of the present study suggest that Sidh
Makardhwaj upto five times the equivalent human
dose administered for 28 days did not show any
toxicological effects on rat brain cerebrum, liver
and kidney
About the formulation Conclusion

5. Pharmacological Evaluation and ChemicalStandardization of an Ayurvedic
Formulation for Wound Healing Activity
The test drug was prepared in the
form of natural ointment with the
plants like Achyranthes aspera,
Allium cepa, and Canabis sativa
under the base of butter in a
specialized form of preparation.
Karuna Sagar Gangopadhyay, MD (Ay)1, Madhuchanda Khan, MVSc, PhD2,
Srikanta Pandit, MD (Ay)1, Shrabana Chakrabarti, MSc, PhD1, Tapan Kumar
Mondal, MVSc, PhD2, and Tuhin Kanti Biswas, MD (Ay), PhD1
The International Journal of Lower Extremity Wounds 2014, Vol. 13(1) 41–49 © The Author(s) 2014 Reprints and
permissions: sagepub.com/journalsPermissions.nav DOI: 10.1177/1534734614520705 ijl.sagepub.com
The West Bengal University of Health Sciences, Kolkata, India West Bengal University of Animal and Fishery Sciences,
Kolkata, India
Pharmacologically the drug KM is found potent in the punch wound model
as evidenced from physical, biochemical,and histological parameters.The plant is also
reported for potent activity in diabetic, burn, and immunocompromised wounds.24 Therefore,
the healing potential of KM may be due to the presence of this important plant. A cepa is
reported to be active against several microorganism like Streptococcus aureus, Bacilus
subtilis, and Pseudomonas aeruginosa.25 The antibacterial property of A cepa is an additional
benefit for treating infected wounds. Butter is used as a good homogenous substance. C sativa,
on the other hand, has the capability of tissue repair due to its anti-inflammatory property.26
Further research is needed to establish its specific mode of action.
About the formulation
Conclusion

6. Preliminary pharmacological evaluation of an
Ayurvedic formulation Dasamularista
Sultana Rajia*, M Shahabuddin Kabir Choudhuri, Mafruhi Sattar and Masum
Shahriar
Department of Pharmacy, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh
Oriental Pharmacy and Experimental Medicine 2006 6(3), 208-214
The results suggest Dasamularista reduced the intestinal
motility in our experimental models and have antidiarrhoeal
effect. Dasamularista did not alter the acetic acid induced
abdominal writhing,but the significant reduction on the onset
of sleeping time and increased duration of sleep indicates the
formulation may have effect on the central nervous system.
Further studies are suggested with individual ingredients and
as a formulation.
About the formulation Conclusion

7. Pharmacognostic evaluation of an ayurvedic
formulation Eladi Gutika
Sunita Shailajan, Sasikumar Menon1, Manasi Yeragi, Vishakha Kelkar
Herbal Research Lab, Ramnarain Ruia College, Matunga, 1Therapeutic Drug Monitoring Laboratory, Sion,
Mumbai, India
DOI:10.4103/0973-8258.94352, International Journal of Green Pharmacy(302-306), Int J
Green Pharm 2011;5:302-6.
Eladi Gutika (EG), is an Ayurvedic polyherbal formulation of
seven ingredients namelyEla (Ellettaria cardamomum),Tejpatra
(Cinnamomumtamala),Tvak(Cinnamomumverum),Pippali(Piperl
ongum),Madhuka(Glycirrhizaglabra),Kharjura,(Phoenixsylvestri
s),Mrdvika (Vitisvinifera), Sita (Sugar) and Madhu (Honey). It is
prescribed for the treatment of cough and asthma. Due to lack of
modern pharmacopoeial standards laid down and followed for
processing of EG, the medicine may not have desired quality and
batch to batch consistency. Hence, there is a need for
standardization of EG using modern bioanalytical tools
Values and the results of such reproducible modern techniques
can make the traditional medicines more acceptable in the local
and global market. Thus, rationally designed, carefully
standardised, synergistic traditional herbal formulations and
botanical drug products with robust scientific evidence can also
be alternative to modern medicin
About the formulation Conclusion

8. WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES
Volume 4, Issue 05, 708-715. Research Article ISSN 2278 – 4357 ,,.
PHARMACOLOGICAL EVALUATION AND DEVELOPMENT OF AN ANTIULCER POLYHERBAL
FORMULATION
Mohammed Sajid, UtkarshaPagdhare* and Vasanti Suvarna
Department of Pharmaceutical Chemistry, S.V.K.M’S, Dr. Bhanuben Nanavati College
of Pharmacy, Mithibhai College Campus, V.M. Road. Vile Parle- (W),
Mumbai - 400 056, India.
(PHF) containing the extracts of
amla(Emblicaofficinalis) fruitsandtulsi(Ocimum
sanctum) leaves, andneem(Azadirachtaindica)
The phytochemical screening of
Embilicaofficinalis,Azadirachtaindica and Ocimum
sanctumextracts,showed presence of
alkaloids,tannins,glycosides and absence of
proteins.The mixture of extracts showed significant
reduction in ulcer index and showed significant ulcer
protectionin ethanol induced ulcer model
About the formulation Conclusion

9. Evaluation of Ayurvedic compound formulations III- Laghugangadhar Churna
Anshu Rathi*, Vartika Rai, Sayyada Khatoon, Subha Rastogi, Ajay
Kumar Singh Rawat, Shanta Mehrotra & M M Pandey
Pharmacognosy and Ethnopharmacology Division, National Botanical Research Institute, Lucknow 226 001, Uttar Pradesh
Indian Journal of Traditional Knowledge Vol. 9 (3), July 2010, pp. 576-580
Lagugangadhar Churna (LGC), a common
compound preparation used for treatment of
diarrhoea and dysentery. This compound
preparation is composed of six medicinal plant
ingredients like exudates of S. malabarica, rhizome
of C. rotundus, stem bark of S. racemosa, flower of
W. fruticosa, fruit pulp of A. marmelos and seeds
of H. antidysenterica.
The development of pharmacopoeial standards of
Laghugangadhar Churna was based on outcome of microscopical,
physicochemical and HPTLC finger print profiles. The results
were found to be highly accurate, quick and reliable for routine
monitoring based on quality control of raw material, processed
powder and compound preparations. The ingredients C. rotundus
and H. antidysenterica are also used in other compound
formulations like Ashwagandhadi churna, Katphaladi churna and
Palashbijadi churna and these preparations can also be
standardized by similar protocols. With the growing demand of
herbal drugs in the herbal drug market, it is suggested that this
standardization tool will help in maintaining the quality and batch
to batch consistency of many important Ayurvedic preparations
including Laghugangadhar Churna
About the formulation Conclusion

10. Evaluation of stability study of Ayurvedic formulation – Rasayana Churna
Biswajyoti Patgiri, Hardik Soni*, Surendra Bhatt
Journal of Pharmacognosy and Phytochemistry 2014; 2 (5): 126-130
Department of Rasashastra &
Bhaishajya Kalpana, Institute forPost Graduate Teaching and Researchin Ayurveda (IPGT&RA), GujaratAyurved University,
Jamnagar – 361008, Gujarat, India.
Rasayana Churna is a traditional Ayurvedic
formulation, which comprises dried powders of three
well known rejuvenating drugs viz. dried stem of
Guduchi (Tinospora cordifolia Miers.), dried fruit of
Gokshur (Tribulus terrestris Linn.) and dried
pericarp of Amalaki (Emblica officinalis Gaertn.) in
equal proportion
The present investigation supports that the Rasayana Churna was
suitable at accelerated condition up to 6 month storage. it can be
extrapolated that shelf life of Rasayana Churna is 25.12 months
(2.09 years) for countries which comes under climatic zone I & II
and 16.60 months (1.38 years) for countries which comes under
climatic zone III & IV. Real time stability data of Rasayana Churna
showed very good stability up to 1 year.
About the formulation Conclusion

11. FORMULATION AND EVALUATION OF CHURNA FOR DIGESTIVE PROPERTY
D. Chamundeeswari a , P. Kanimozhi a, Vasanthkumar a,
C.Umamaheswara Reddy a
Sri Ramachandra Journal of Medicine Nov. 2007,(39-43)
Department of Pharmacognosy Sri Ramachandra College of Pharmacy Sri Ramachandra University,
Porur, Chennai – 600 116 Sri Ramachandra College of Pharmacy
The raw materials such as rhizomes of Zingiber
officinale (2 parts), fruits of Foeniculum vulgarae (2
parts), barks of Cinnamomum zeylanicum (1 part)
and fruits of Trachyspermum ammi (1 part) were
used for the preparation of the formulation
The physical parameters evaluated confirm the standard
of the formulated churna. The invitro study of enzymatic
activity carried out by above methods brings out the fact
that the formulated churna possess the property of digesting
starch, lipids and proteins similar to that of marketed
formulation GASTRAP.
About the formulation Conclusion

12. THANKYOU SIR