2. What are Regenerative
Medicines?
The main aim of Regenerative Medicines is to restore the
function of deceased or damaged tissues or organs using a
variety of approaches. From cell based through tissue
engineering to develop new medical devices, regenerative
medicine potentially offers huge benefits.
3. People suffering from chronic
debilitating illnesses are currently
faced with a relatively short list of
options:
Long Term
Drug
Therapy
Organ
Transplant
Medical Devices
(Eg. Pacemakers)
8. Cellular Therapy
– Each of the 200+ types of cells in the
Human Body has been derived from
a single cell- the fertilized egg.
– As the fertilized egg develops, it
forms Embryonic Stem Cells (ESCs).
– As the cells develop, they
differentiate into more specialized
cell types and organize into
structures that become tissues and
organs.
9. Autologous Therapy
This therapy is done using a
patient’s own cells. Different
aspects to this therapy are still
subject to on- going tests at two
London Hospitals which treats
100 heart attack patients with
stem cells from their own bone
marrow to help repair damaged
heart tissue. Initial results from
such studies have been
encouraging.
10. Allogenic Therapy
This therapy uses cells from
matched donors. The London
Project to cure Blindness from
June 2007 aimed to develop a
cure for age- related eye sight
degeneration using matched
donors. This approach may pose
more concerns as they have the
potential to cause immune
rejection and may be given to
multiple people.
11. Tissue Engineering
This involves modifying cells or
tissues in some ways so that they
can repair, regenerate or replace
tissue in the body. Perhaps the
best known example of such an
approach was the tissue
engineered section of windpipe
made of a patient whose airways
had been severely damaged by
tuberculosis.
12. Gene Therapy
There are different approaches
to gene therapy, the most
obvious is to identify a medical
condition that can be treated by
a specific protein, and then to
deliver the gene coding for that
protein to the affected cells.