Progynova is used as a Hormone Replacement Therapy (HRT) to alleviate the oestrogen deficiency symptoms like such as hot flushes, sweats, sleep disturbances, depressive moods, irritability, dizziness, headaches as well as vaginal dryness and burning in peri- and postmenopausal women. This medicine is also used for prevention of postmenopausal osteoporosis in cases where other medicines are not suitable for the patient and are at risk of of fractures due to osteoporosis.