Per contact probability of infection by Highly Pathogenic Avian Influenza
Preview of “asymptomatic Beijing H7N9 raises pandemic concerns” copy
1. Asymptomatic Beijing H7N9 Raises Pandemic Concerns http://www.recombinomics.com/News/04141302/H7N9_Beiji...
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Asymptomatic Beijing H7N9 Raises Pandemic Concerns
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Recombinomics Commentary 21:13
Vaccine Screening
April 14, 2013
active screening monitoring 4-year-old bamboo surname boys H7N9
Vaccine Development
avian influenza virus nucleic acid positive. The boy is currently no clinical
Expression Profiling symptoms
Drug Discovery The above translation describes an asymptomatic contact (4M) of the
index case (7F) in Beijing. The case was identified through screening of
Custom Therapies contacts of the earlier case. The detection of H7N9 is an asymptomatic
contacts raises concerns that H7N9 is far more widespread than
Patents represented by the 61 confirmed cases (see map), which includes 13
fatalities.
The confirmed cases have a case fatality are of more than 92% (13
fatalities out of 14 outcomes). All of the other confirmed cases are
hospitalized, including the above case who was hospitalized for
observation.
Sequences from this case would be useful. There are 4 public
sequences and all 4 have E627K. These sequences are from fatal
cases. Avian isolates are lacking E627K, but have Q226L. Differences
between severe / fatal cases and mild / asymptomatic cases remain to
be determined.
However, the detection of H7N9 in an asymptomatic contact raises
serious pandemic concerns.
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