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Asymptomatic Beijing H7N9 Raises Pandemic Concerns                     http://www.recombinomics.com/News/04141302/H7N9_Beiji...




                                             Home      Founder       What's New       In The News         Consulting



           H1N1 Consulting
                                             Audio:Feb11 Feb21 Mar21 Apr4             twitter
           Paradigm Shift

           Viral Evolution
                                             Commentary
                                             Asymptomatic Beijing H7N9 Raises Pandemic Concerns
           Intervention Monitoring
                                             Recombinomics Commentary 21:13
           Vaccine Screening
                                             April 14, 2013
                                             active screening monitoring 4-year-old bamboo surname boys H7N9
           Vaccine Development
                                             avian influenza virus nucleic acid positive. The boy is currently no clinical
           Expression Profiling              symptoms

           Drug Discovery                    The above translation describes an asymptomatic contact (4M) of the
                                             index case (7F) in Beijing. The case was identified through screening of
           Custom Therapies                  contacts of the earlier case. The detection of H7N9 is an asymptomatic
                                             contacts raises concerns that H7N9 is far more widespread than
           Patents                           represented by the 61 confirmed cases (see map), which includes 13
                                             fatalities.

                                             The confirmed cases have a case fatality are of more than 92% (13
                                             fatalities out of 14 outcomes). All of the other confirmed cases are
                                             hospitalized, including the above case who was hospitalized for
                                             observation.

                                             Sequences from this case would be useful. There are 4 public
                                             sequences and all 4 have E627K. These sequences are from fatal
                                             cases. Avian isolates are lacking E627K, but have Q226L. Differences
                                             between severe / fatal cases and mild / asymptomatic cases remain to
                                             be determined.

                                             However, the detection of H7N9 in an asymptomatic contact raises
                                             serious pandemic concerns.

                                             Media Link

                                             Recombinomics Presentations

                                             Recombinomics Publications

                                             Recombinomics Paper at Nature Precedings




1 of 2                                                                                                            4/15/13 5:22 PM
Asymptomatic Beijing H7N9 Raises Pandemic Concerns                 http://www.recombinomics.com/News/04141302/H7N9_Beiji...




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                                        © 2013 Recombinomics. All rights reserved.




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Preview of “asymptomatic Beijing H7N9 raises pandemic concerns” copy

  • 1. Asymptomatic Beijing H7N9 Raises Pandemic Concerns http://www.recombinomics.com/News/04141302/H7N9_Beiji... Home Founder What's New In The News Consulting H1N1 Consulting Audio:Feb11 Feb21 Mar21 Apr4 twitter Paradigm Shift Viral Evolution Commentary Asymptomatic Beijing H7N9 Raises Pandemic Concerns Intervention Monitoring Recombinomics Commentary 21:13 Vaccine Screening April 14, 2013 active screening monitoring 4-year-old bamboo surname boys H7N9 Vaccine Development avian influenza virus nucleic acid positive. The boy is currently no clinical Expression Profiling symptoms Drug Discovery The above translation describes an asymptomatic contact (4M) of the index case (7F) in Beijing. The case was identified through screening of Custom Therapies contacts of the earlier case. The detection of H7N9 is an asymptomatic contacts raises concerns that H7N9 is far more widespread than Patents represented by the 61 confirmed cases (see map), which includes 13 fatalities. The confirmed cases have a case fatality are of more than 92% (13 fatalities out of 14 outcomes). All of the other confirmed cases are hospitalized, including the above case who was hospitalized for observation. Sequences from this case would be useful. There are 4 public sequences and all 4 have E627K. These sequences are from fatal cases. Avian isolates are lacking E627K, but have Q226L. Differences between severe / fatal cases and mild / asymptomatic cases remain to be determined. However, the detection of H7N9 in an asymptomatic contact raises serious pandemic concerns. Media Link Recombinomics Presentations Recombinomics Publications Recombinomics Paper at Nature Precedings 1 of 2 4/15/13 5:22 PM
  • 2. Asymptomatic Beijing H7N9 Raises Pandemic Concerns http://www.recombinomics.com/News/04141302/H7N9_Beiji... Home | Founder | What's New | In The News | Contact Us Webmaster: webmaster@recombinomics.com © 2013 Recombinomics. All rights reserved. 2 of 2 4/15/13 5:22 PM